Adela María Guirado-Vico, Mª Carmen Rodríguez-García
{"title":"Effectiveness of Antiseptic and Antibiotic Use to Prevent Central Line-Associated Bloodstream Infections in ICU Patients: A Systematic Review and Narrative Synthesis of Randomized Clinical Trials.","authors":"Adela María Guirado-Vico, Mª Carmen Rodríguez-García","doi":"10.1097/NAN.0000000000000645","DOIUrl":"10.1097/NAN.0000000000000645","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to conduct a narrative synthesis of randomized trials to evaluate the evidence on the effectiveness of antibiotics and antiseptics in preventing central line-associated bloodstream infection (CLABSI) in intensive care unit patients.</p><p><strong>Methods: </strong>A systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, CINAHL, and Scopus databases were searched for randomized controlled trials published from 2012 to March 2024. The methodological quality of the included studies was independently evaluated by 2 reviewers using the Critical Appraisal Skills Programme Spanish [Español] appraisal tool. Following data extraction, a narrative synthesis was performed to integrate and interpret the findings across studies. The protocol was registered in advance in the Prospective Register of Systematic Reviews (PROSPERO).</p><p><strong>Results: </strong>Nineteen randomized trials were appraised using the Critical Appraisal Skills Programme Spanish [Español] tool, of which 13 high-quality studies (score ≥6) were included in the review. These trials assessed antiseptic (alcohol, chlorhexidine), antibiotic (rifampin), or combined interventions versus standard care. Antiseptic and antibiotic-impregnated catheters and alcohol caps were associated with reduced CLABSI rates, hospital stay, and costs, while evidence for alcohol lock therapy was inconclusive.</p><p><strong>Conclusion: </strong>This review supports the use of antiseptic and antibiotic-coated catheters as promising measures to prevent CLABSI in critically ill patients. However, caution is warranted with alcohol lock therapy due to limited and conflicting evidence.</p>","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 5","pages":"298-308"},"PeriodicalIF":4.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Clinical and Economic Value of ClearGuard HD in the Inpatient Setting for Hemodialysis Catheter Management.","authors":"Max Holder, Jason Battle, Jamie Kelly","doi":"10.1097/NAN.0000000000000654","DOIUrl":"10.1097/NAN.0000000000000654","url":null,"abstract":"<p><strong>Objective: </strong>This study was the first to assess inpatient use of ClearGuardTM HD antimicrobial barrier caps for the reduction of hemodialysis catheter-related central line-associated bloodstream infections (CLABSI) compared to the use of Tego™️ needlefree connectors with Curos™️ caps.</p><p><strong>Methods: </strong>Retrospective observational data were used to evaluate the effect of ClearGuard on the CLABSI rate and standardized infection ratio (SIR) compared to the baseline rate and ratio. Financial analysis was conducted to measure return on investment.</p><p><strong>Results: </strong>Compared to the baseline period, data from the implementation period showed a long-term CLABSI reduction from 1.91/month/site (95% CI: [0.91-4.00]) to 0.71/month/site (95% CI: [0.33-1.53]), a 63% reduction (95% CI: [46%-74%]) in CLABSIs (P < .00005). The overall SIR was reduced by 57%, from a baseline of 0.721 to 0.310. The annual cost savings were estimated at $1.6 million.</p><p><strong>Conclusion: </strong>The findings from the ClearGuard study and ongoing use across hospitals indicate a clinically significant reduction in hemodialysis catheter-related CLABSI events and associated costs.</p>","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 5","pages":"269-277"},"PeriodicalIF":4.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13533473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Blacker, Nathalia Guarienti Missima, Gustaf Ljungman, Peter Frykholm
{"title":"Need-Based Innovation: From Idea to Evidence in Vascular Access.","authors":"Christopher Blacker, Nathalia Guarienti Missima, Gustaf Ljungman, Peter Frykholm","doi":"10.1097/NAN.0000000000000651","DOIUrl":"10.1097/NAN.0000000000000651","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to describe the Biodesign methodology and its application in developing and evaluating a new medical device to reduce short peripheral intravenous catheter dislodgement.</p><p><strong>Methods: </strong>First, the Stanford Biodesign method, a systematic process for designing new medical technologies, was presented in six detailed steps. Second, examples from a recently published randomized clinical trial were used to illustrate how Biodesign can be applied to identify unmet needs in vascular access, generate concepts, and validate a solution.</p><p><strong>Results: </strong>The resulting product from the Biodesign process was a type of force-activated separation device (FASD). The trial of the FASD demonstrated a 73% relative risk reduction in short peripheral intravenous catheter dislodgement in the intervention group compared with the control, with no device-related adverse events. Other complication rates remained unchanged.</p><p><strong>Conclusions: </strong>The Biodesign methodology offers a systematic approach to innovation in infusion therapy. The FASD case illustrates how need-driven design and evidence generation can produce clinically meaningful solutions.</p>","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 5","pages":"261-268"},"PeriodicalIF":4.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multi-Chamber Bag Parenteral Nutrition: A Brief Review of Clinical Applications.","authors":"Andrew Mays","doi":"10.1097/NAN.0000000000000660","DOIUrl":"https://doi.org/10.1097/NAN.0000000000000660","url":null,"abstract":"","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 5","pages":"278-281"},"PeriodicalIF":4.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial Intelligence Competency: A New Imperative for Infusion Nurses.","authors":"Susan Lown","doi":"10.1097/NAN.0000000000000663","DOIUrl":"https://doi.org/10.1097/NAN.0000000000000663","url":null,"abstract":"","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 5","pages":"259-260"},"PeriodicalIF":4.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soon Yeng Soo Hoo, Joan Uy, Anne McDade, Julie Ji Yeon Hyun, Karla Aguiba, Michelle Waite, Niantao Deng, David Brieger
{"title":"Patient Self-Monitoring of Peripheral Intravenous Catheters Using the Visual Infusion Phlebitis Score: A Pilot Study.","authors":"Soon Yeng Soo Hoo, Joan Uy, Anne McDade, Julie Ji Yeon Hyun, Karla Aguiba, Michelle Waite, Niantao Deng, David Brieger","doi":"10.1097/NAN.0000000000000655","DOIUrl":"10.1097/NAN.0000000000000655","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate patients' knowledge of using the Visual Infusion Phlebitis (VIP) score for self-monitoring of peripheral intravenous catheters (PIVCs) during hospitalization.</p><p><strong>Methods: </strong>A descriptive comparative pilot study was conducted on 64 inpatients aged ≥18 years by using a structured Patient Knowledge Evaluation Questionnaire (PKEQ) on days 1, 2, and 3 of hospitalization. Patients received education on using the VIP score after admission. Patient knowledge levels, phlebitis scores, and major adverse events were compared between younger participants aged ≥18 years to <70 years and older participants aged >70 years.</p><p><strong>Results: </strong>Results were statistically significant for patient knowledge of using the VIP score on day 1 (P < .015) and day 2 (P < .037) after PIVC insertion but not for day 3. Patients' accuracy of scoring was comparable with nurses' scores. Major in-hospital adverse events were not statistically different. Patients of all ages ≥18 years to >70 years applied their knowledge of the VIP score for accurate assessment and monitoring of their PIVCs for visual signs of phlebitis.</p><p><strong>Conclusion: </strong>These findings could guide innovative clinical practice developments in safe PIVC care by promoting patient education on using the VIP score for early visual detection of PIVC-related complications.</p>","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 5","pages":"282-297"},"PeriodicalIF":4.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nursing Continuing Professional Development for Nursing Contact Hours and CRNI® Recertification Units.","authors":"","doi":"10.1097/NAN.0000000000000669","DOIUrl":"https://doi.org/10.1097/NAN.0000000000000669","url":null,"abstract":"","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 5","pages":"E16-E19"},"PeriodicalIF":4.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natasha Marques Frota, Odézio Damasceno Brito, Francisco Marcelo Leandro Cavalcante, Mariana de Jesus Meszaros, Ana Clécia Silva Monteiro, Ana Luiza Coelho Martins, Livia Moreira Barros, Ana Railka de Souza Oliveira Kumakura
{"title":"Approaches to Teaching Peripheral Venous Puncture: A Scoping Review.","authors":"Natasha Marques Frota, Odézio Damasceno Brito, Francisco Marcelo Leandro Cavalcante, Mariana de Jesus Meszaros, Ana Clécia Silva Monteiro, Ana Luiza Coelho Martins, Livia Moreira Barros, Ana Railka de Souza Oliveira Kumakura","doi":"10.1097/NAN.0000000000000643","DOIUrl":"10.1097/NAN.0000000000000643","url":null,"abstract":"<p><p>This scoping review aimed to describe and analyze educational methodologies used for teaching peripheral venipuncture to nursing students. The study was conducted according to the guidelines of the Joanna Briggs Institute and the PRISMA-ScR. Primary studies that addressed educational methodologies used for teaching peripheral venipuncture were included. The research question was as follows: \"What are the educational methodologies used for teaching nursing students about peripheral venipuncture?\" The searches were carried out in the MEDLINE, SciELO, LILACS, BDENF, Embase, Scopus, and ScienceDirect databases. The results were evaluated through the synthesis of the selected articles. Thirty-seven studies were included, and the most frequent methodologies were clinical simulation with manikins, educational hypermedia, instructional videos, digital games, interactive software, and virtual reality. Simulation was noted for enhancing technical performance, while digital resources promoted engagement, self-confidence, and autonomous learning. The most common study designs were experimental, descriptive, and methodological, with the use of validated instruments to assess knowledge, skills, and student perception. The mapped educational methodologies facilitate the teaching of peripheral venipuncture, contributing to the development of technical competencies and safety in practice. The adoption of hybrid approaches, integrating digital technologies with supervised practice, is recommended to strengthen nursing education in peripheral venipuncture.</p>","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 4","pages":"224-237"},"PeriodicalIF":4.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shanshan Wu, Zhanzhi Peng, Jie Chen, Heting Meng, A-Li Wang, Yihong Qiu, Wanjiao Li
{"title":"Incidence and Risk Factors of Catheter-Related Thrombosis in Oncology Patients With Internal Jugular and Subclavian Implanted Ports: A Retrospective Single-Center Study.","authors":"Shanshan Wu, Zhanzhi Peng, Jie Chen, Heting Meng, A-Li Wang, Yihong Qiu, Wanjiao Li","doi":"10.1097/NAN.0000000000000652","DOIUrl":"10.1097/NAN.0000000000000652","url":null,"abstract":"<p><strong>Objective: </strong>This study compared the clinical characteristics of catheter-related thrombosis (CRT) associated with internal jugular and subclavian vein-implanted ports.</p><p><strong>Methods: </strong>This retrospective study enrolled patients who were newly implanted with a vascular access port between January and December 2022. Relevant patient and clinical information, including demographic data, catheter details, and CRT results, were mainly obtained from the hospital's electronic medical record database. Follow-up was conducted until the time of the patient's first occurrence of thrombus at the infusion port or the last vascular color Doppler ultrasound available for patients without thrombus up to the study deadline (December 2024).</p><p><strong>Results: </strong>Among 647 patients who underwent B-ultrasound examinations due to different reasons, such as discomfort symptoms, catheter dysfunction, and pre-extubation thrombus screening, 277 patients (42.8%) experienced CRT, and the median time to thrombosis was 14 (12, 16) months. It was most frequently located at the entrance of the catheterized vein (36.6%). Breast cancer and internal jugular vein catheterization were risk factors for CRT. After pairwise comparisons, there was a significant difference in the median time (4 [2, 7] vs 5 [3, 10] months) between the early onset thrombus (hypoechoic), and older thrombi (hyperechoic signal) (adjusted P = .021).</p><p><strong>Conclusion: </strong>For cancer patients who undergo ultrasound examinations for various reasons, the risk of CRT is relatively high. More attention should be paid to patients with breast cancer and with internal jugular vein implantation around 14 months after catheterization.</p>","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 4","pages":"238-248"},"PeriodicalIF":4.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Ethylene Tetrafluoroethylene (ETFE) and Polypropylene (PP) Peripheral Intravenous Catheter Biomaterials on the Incidence of Phlebitis.","authors":"Indra Atsah, Takdir Tahir, Yuliana Syam","doi":"10.1097/NAN.0000000000000648","DOIUrl":"10.1097/NAN.0000000000000648","url":null,"abstract":"<p><p>This study was conducted to determine the relationship between the peripheral intravenous catheter biomaterial type and the incidence of phlebitis. This prospective cohort study aims to determine the effect of ethylene tetrafluoroethylene (ETFE) and polypropylene (PP) biomaterials on the incidence of phlebitis. The study was conducted in the internal medicine ward of 1 of the hospitals in Makassar City, Indonesia. Phlebitis was assessed using the Visual Infusion Phlebitis scale based on the Maddox scale. Data were analyzed using SPSS software version 23. A total of 30 samples were included in this study, each consisting of 15 samples in the ETFE and PP biomaterial groups. The analysis showed a significant difference in the duration of catheter use until the occurrence of phlebitis between the 2 groups (P = .05). However, there were significant differences in the scale of phlebitis (P = .01) and bacterial count (P = .002), where PP biomaterial showed a higher rate of phlebitis occurrence and bacterial colonization than ETFE. These findings suggest that PP biomaterials are more prone to cause phlebitis than ETFE. Therefore, nurses are advised to be more selective in choosing the peripheral intravenous catheter biomaterial type to minimize the risk of phlebitis complications in patients.</p>","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 4","pages":"213-220"},"PeriodicalIF":4.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}