Acta Dermatovenerologica Alpina Pannonica et Adriatica最新文献_第9页

HIV-1 subtype diversity and phylogenetic insight into non-B subtype transmission in Slovenia, 1989-2013 1989-2013年斯洛文尼亚HIV-1亚型多样性和非b亚型传播的系统发育观察

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.20

Jana Mlakar, Maja M. Lunar, Ana B. Abecasis, Anne-Mieke Vandamme, Janez Tomažič, Tomaž D. Vovko, Blaž Pečavar, Gabriele Turel, Mario Poljak

{"title":"HIV-1 subtype diversity and phylogenetic insight into non-B subtype transmission in Slovenia, 1989-2013","authors":"Jana Mlakar, Maja M. Lunar, Ana B. Abecasis, Anne-Mieke Vandamme, Janez Tomažič, Tomaž D. Vovko, Blaž Pečavar, Gabriele Turel, Mario Poljak","doi":"10.15570/actaapa.2023.20","DOIUrl":"https://doi.org/10.15570/actaapa.2023.20","url":null,"abstract":"Disease progression, drug resistance mutations, and treatment strategies may vary by HIV-1 subtype. This study determined HIV-1 subtypes circulating in Slovenia, a Central European country with an HIV-1 epidemic driven by men who have sex with men, focusing on molecular epidemiology of non-B subtypes.A total of 367 HIV-1 sequences were included. Subtype was assigned by employing eight different HIV subtyping tools coupled with maximum likelihood phylogenetic analyses.The subtyping tools COMET, jpHMM, and REGA 3.0 exhibited the best performance on the dataset studied. Phylogenetic analyses showed a 14.7% prevalence of non-B subtypes, with subtype A detected most frequently (4.9%), followed by CRF02_AG (2.4%), subtype C (1.1%), subtypes D, G, and CRF01_AE (0.8% each), and subtypes F and CRF22_01A1 (0.3% each). A subtype could not be assigned to 12 sequences (3.3%), indicating potential unique recombinant forms. Non-B subtypes were significantly associated with a heterosexual route of transmission and infection acquired in Eastern Europe, Africa, or Asia.In a country where subtype B is predominant, non-B subtypes were observed in one out of seven patients, a non-negligible proportion, which underlines the importance of systematic surveillance of HIV subtype diversity and the corresponding molecular epidemiology.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thirty years of Acta Dermatovenerologica Alpina Pannonica et Adriatica: from the journal’s beginnings to an impact factor 《亚得里亚海皮肤病性病学报》三十年:从期刊创刊到影响因子

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.15

Jovan Miljković, Anja Šterbenc

引用次数: 0

Molecular epidemiology of the 2022 monkeypox virus outbreak in Slovenia 斯洛文尼亚2022年猴痘病毒暴发的分子流行病学

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.21

Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Nataša Knap, Alen Suljič, Tomaž Mark Zorec, Maja Mastnak, Miroslav Petrovec, Mario Poljak, Misa Korva, Tatjana Avšič-Županc

{"title":"Molecular epidemiology of the 2022 monkeypox virus outbreak in Slovenia","authors":"Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Nataša Knap, Alen Suljič, Tomaž Mark Zorec, Maja Mastnak, Miroslav Petrovec, Mario Poljak, Misa Korva, Tatjana Avšič-Županc","doi":"10.15570/actaapa.2023.21","DOIUrl":"https://doi.org/10.15570/actaapa.2023.21","url":null,"abstract":"Monkeypox virus (MPXV), typically endemic in West and Central Africa, has raised global concern due to the recent outbreak in several non-endemic countries with human-to-human transmission. Here we present a comprehensive analysis of MPXV genomes from Slovenia.Two real-time polymerase chain reaction (RT-PCR) assays for Orthopoxvirus (OPV) and MPXV genes were used for laboratory confirmation of mpox. Complete MPXV genomic sequences were obtained using nanopore long reads and Illumina technology. Phylogenetic analyses compared the Slovenian MPXV sequences with the global sequences.A total of 49 laboratory-confirmed mpox cases were diagnosed in Slovenia in 2022, mainly affecting males under 40. In 48 cases, a complete genome sequence was obtained and phylogenetic analysis revealed five distinct lineages (B.1, B.1.14, B.1.2, B.1.3, and A.2.1), with B.1 and B.1.3 dominating, suggesting multiple introductions into Slovenia. Genome analysis revealed significant divergence from the reference MPXV-M5312_HM12_Rivers.The genetic diversity observed in the Slovenian MPXV sequences sheds light on the complex dynamics of the 2022 mpox outbreak and highlights the need for further research to understand the impact of mutations on MPXV functional characteristics and their role in the evolution and diversification of current lineages.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the incidence of anogenital warts and serological test results for other sexually transmitted infections 肛门生殖器疣发病率及其他性传播感染血清学检测结果分析

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.17

Neşe Göçer Gürok

{"title":"Analysis of the incidence of anogenital warts and serological test results for other sexually transmitted infections","authors":"Neşe Göçer Gürok","doi":"10.15570/actaapa.2023.17","DOIUrl":"https://doi.org/10.15570/actaapa.2023.17","url":null,"abstract":"Anogenital warts (AGWs) are proliferative lesions mainly presenting in the anal, genital, and perianal regions. They are one of the most prevalent sexually transmitted infections globally.The study included patients that presented at the Dermatology Clinic of Health Sciences, University Elaziğ, Fethi Sekin City Hospital between January 2019 and December 2022 and were diagnosed with AGWs. Patients that presented with this diagnosis and were screened for other sexually transmitted infections (HBsAg, anti-HBs, anti-HCV, anti-HIV, VDRL, and TPHA) were identified. Epidemiological and demographic patient data and the results of serological tests for other sexually transmitted infections in the last 4 years were analyzed. The patient data and examination results were collected retrospectively based on the hospital automated patient records.AGW incidence was significantly higher in males. The mean patient age was 32, and the mean female patient age was lower than that of males. It was observed that the number of patients that were followed up with an AGW diagnosis increased significantly during the last 4 years (p < 0.05). The study detected 2.2% HBsAg, 0.6% TPHA, 0.3% VDRL, 0.5% anti-HCV, and 56.5% anti-HBs positivity. No anti-HIV-positive patients were identified. None of the patients had more than one sexually transmitted infection on serology testing.Although the serological findings were higher when compared to certain studies and quite low when compared to others, it would be beneficial to evaluate all patients with AGWs for other sexually transmitted infections.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positivity of celiac disease–specific antibodies and non-celiac hypersensitivity in psoriasis 牛皮癣患者乳糜泻特异性抗体阳性和非乳糜泻超敏反应

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.18

Marina Vekić-Mužević, Lucija Tomić, Nives Pondeljak, Elvira Lazić Mosler

{"title":"Positivity of celiac disease–specific antibodies and non-celiac hypersensitivity in psoriasis","authors":"Marina Vekić-Mužević, Lucija Tomić, Nives Pondeljak, Elvira Lazić Mosler","doi":"10.15570/actaapa.2023.18","DOIUrl":"https://doi.org/10.15570/actaapa.2023.18","url":null,"abstract":"Plaque psoriasis and celiac disease are multisystemic diseases. The association of psoriasis and enteropathy with histological changes similar to celiac disease has already been described, and it has also been found that a gluten-free diet improves psoriatic changes. This study assesses the relationship between celiac disease antibodies and psoriasis.The study included 112 participants: 60 with psoriasis in a test group and 52 healthy subjects in a control group. Within the psoriasis group, participants were further divided into two subgroups: one consisting of patients with both psoriasis and psoriatic arthritis (n = 17) and another comprising patients with psoriasis alone (n = 43). After informed consent was obtained, the Dermatology Life Quality Index (DLQI) score and Psoriasis Area and Severity Index (PASI) score were evaluated. Laboratory tests included assessment of anti-deaminated gliadin peptide antibodies (DGP), anti-gliadin antibodies (AGA), and anti-tissue transglutaminase antibodies (tTG).Immunoglobulin G (IgG) and immunoglobulin A (IgA) DGP antibodies were detected more frequently and at higher serum concentrations in patients with psoriasis compared to healthy controls (p = 0.03, p = 0.04, respectively). Similarly, elevated levels of IgG-tTG antibodies (p = 0.003) and IgA-DGP antibodies (p = 0.02) were observed in the same test group.A relationship between positivity to celiac disease antibodies and psoriasis, particularly with regard to AGA, has been identified. Further studies are required to elucidate the nature, pathophysiology, and significance of these findings.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic radiation dermatitis induced by cardiac catheterization: a case report and literature review. 心导管置管诱发慢性放射性皮炎1例并文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2022-12-01 DOI: 10.15570/actaapa.2022.25

Ting-Ting Cheng, Hui-Ju Yang

引用次数: 0

A diagnostic challenge in an atypical variant of microcystic adnexal carcinoma mimicking ulcerative basal cell carcinoma: a case report and brief literature review. 模拟溃疡性基底细胞癌的微囊性附件癌的非典型变异的诊断挑战:一个病例报告和简短的文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2022-12-01

Nurul Indah Pratiwi, Khairuddin Djawad, Jonathan Kurnia Wijaya, Mahmud Ghaznawie, Siswanto Wahab, Airin Nurdin

{"title":"A diagnostic challenge in an atypical variant of microcystic adnexal carcinoma mimicking ulcerative basal cell carcinoma: a case report and brief literature review.","authors":"Nurul Indah Pratiwi, Khairuddin Djawad, Jonathan Kurnia Wijaya, Mahmud Ghaznawie, Siswanto Wahab, Airin Nurdin","doi":"","DOIUrl":"","url":null,"abstract":"Microcystic adnexal carcinoma (MAC) is a rare adnexal tumor with eccrine and pillar differentiations with a localized and aggressive nature, often misdiagnosed as other dermatoses. The most common clinical manifestations of MAC are yellowish or skin-colored papules, nodules, and plaques. However, in some rare cases an atypical manifestation such as ulceration that resembles malignancies such as basal cell carcinoma (BCC) can also occur. Diagnosis of MAC mainly relies on the aid of histopathology. Due to potential infiltration to other structures such as in perineural invasion, wide surgical excision or Mohs micrographic surgery is the preferred surgical option. We report the case of a 75-year-old male patient with ulcerative lesion on the forehead that clinically resembled BCC in addition to typical dermoscopic findings of BCC. However, histopathology confirmed a diagnosis of MAC, prompting physicians to be more aware of this condition when encountering chronic ulcerative lesions. After wide excision and a 1-year follow-up, the patient exhibited no signs of recurrences and will continue long-term follow-up.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body-focused repetitive behaviors in children and adolescents, clinical characteristics, and the effects of treatment choices on symptoms: a single-center retrospective cohort study. 儿童和青少年以身体为中心的重复行为、临床特征和治疗选择对症状的影响:一项单中心回顾性队列研究

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2022-12-01 DOI: 10.15570/actaapa.2022.24

Zehra Topal Hangül, T. Tuman, Bengü Altunay-Tuman, Gizem Saygılı, A. Tufan

{"title":"Body-focused repetitive behaviors in children and adolescents, clinical characteristics, and the effects of treatment choices on symptoms: a single-center retrospective cohort study.","authors":"Zehra Topal Hangül, T. Tuman, Bengü Altunay-Tuman, Gizem Saygılı, A. Tufan","doi":"10.15570/actaapa.2022.24","DOIUrl":"https://doi.org/10.15570/actaapa.2022.24","url":null,"abstract":"INTRODUCTION\u0000This study determines clinical features of body-focused repetitive behaviors (BFRBs) among a sample of Turkish children and adolescents, evaluates the naturalistic treatments selected in this sample, and determines the effects of those treatments during a 3-month follow-up.\u0000\u0000\u0000METHODS\u0000The study included a cohort of 67 patients 9 to 17 years old attending a tertiary center between March and June 2013 with complaints of nail biting, skin picking, and/or hair pulling. The patients completed psychometric scales and were evaluated for symptom severity, improvement, and adverse effects after an initial interview and at control visits during the 4th and 8th weeks.\u0000\u0000\u0000RESULTS\u0000The most common BFRB was nail biting. In nail-biting behavior, subjective awareness was higher, and urges prior to the behavior and release after the behavior were found to be higher. Although there was no significant difference between the choice of treatment and the course of psychiatric measures, significant improvement was found in functionality after treatment.\u0000\u0000\u0000CONCLUSIONS\u0000Despite its limitations, the small number of studies on BFRBs increases the importance of studies in this area.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90728298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of top-cited articles on melanoma. 关于黑色素瘤的热门文章分析。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2022-12-01

Ka Siu Fan, Ka Hay Fan, Pak Lim Tse, Hao Ding, Runqing Su, Hiu Tat Kwok

{"title":"Analysis of top-cited articles on melanoma.","authors":"Ka Siu Fan, Ka Hay Fan, Pak Lim Tse, Hao Ding, Runqing Su, Hiu Tat Kwok","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: This bibliometric analysis evaluates the most influential studies in clinical research on melanoma.Methods: Based on the bibliometric theory, articles in the Thomson Reuters Web of Science database were analyzed. Full English-language articles were searched for using the terms melanoma, superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma, and acral lentiginous melanoma. The 100 most-cited articles were analyzed by topic, author, journal of publication, year of publication, institution, and country of origin.Results: The search returned 243,109 articles, with the majority from the past 3 decades: 1991-2000 (n = 29), 2001-2010 (n = 28), and 2011-2020 (n = 30). The top 100 cited articles had mean and median citations of 2,159 and 1,793, respectively. An article on the use of ipilimumab in metastatic melanoma, by Hodi et al., was most cited (8,150). The New England Journal of Medicine had the most citations (58,489), and Nature published the most articles (n = 21). The United States published the most articles (n = 81), led by the National Cancer Institute (n = 16). The majority of articles explored management (n = 68), prognosis (n = 57), and immunotherapy (n = 27).Conclusions: This analysis serves as a guide for future research and highlights key areas of research, particularly in genetics and immunotherapy, that have influenced current knowledge of melanoma.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic radiation dermatitis induced by cardiac catheterization: a case report and literature review. 心导管置管诱发慢性放射性皮炎1例并文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2022-12-01

Ting Ting Cheng, Hui-Ju Yang

引用次数: 0