Acta Dermatovenerologica Alpina Pannonica et Adriatica最新文献_第9页

Oral postbiotics derived from Lactobacillus sp. in treatment of atopic dermatitis: a meta-analysis. 从乳杆菌中提取的口服后生物制剂治疗特应性皮炎:一项荟萃分析。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-06-01

Natalia Tanojo, Irmadita Citrashanty, Budi Utomo, Yulianto Listiawan, Evy Ervianti, Damayanti, Sawitri

{"title":"Oral postbiotics derived from Lactobacillus sp. in treatment of atopic dermatitis: a meta-analysis.","authors":"Natalia Tanojo, Irmadita Citrashanty, Budi Utomo, Yulianto Listiawan, Evy Ervianti, Damayanti, Sawitri","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The use of postbiotics, which are defined as dead microorganisms and/or their components that provide health benefits to the target host, has been shown to reduce the severity of atopic dermatitis (AD) in several studies.Methods: A systematic literature review was conducted in Pubmed, the Cochrane Library, Science Direct, Clinicaltrials.gov, and Google Scholar, covering the period from January 2012 to July 2022 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. AD patients of all ages that received oral postbiotics or placebo as treatment were the focus of the study. The main study outcome was the scoring of atopic dermatitis (SCORAD) and other measures, such as extension area, disease intensity, and adverse events. The final data were pooled using a fixed-effect model.Results: A meta-analysis of three studies found that, compared to placebo, SCORAD was lower in subjects that were given oral postbiotics from Lactobacillus sp. (mean difference: -2.90, 95% confidence interval [CI; -4.21, -1.59], p < 0.00001). From the comparison of two studies, the differences in disease extension (mean difference: -2.40, 95% CI [-7.67, 2.81], p = 0.37) and intensity (mean difference: -0.27, 95% CI [-0.84, 0.30], p = 0.36) were not significant.Conclusions: The administration of oral postbiotics from Lactobacillus sp. has the potential to alleviate the severity of AD as indicated by a reduction in SCORAD scores.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 2","pages":"41-47"},"PeriodicalIF":1.2,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9692907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proposal of Slovenian guidelines for the diagnosis of neonatal erythroderma with a case report of Omenn syndrome. 斯洛文尼亚新生儿红皮病诊断指南的建议与奥曼综合征病例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-06-01

Mateja Starbek Zorko, Ana Štublar Krašovec, Vlasta Dragoš

{"title":"Proposal of Slovenian guidelines for the diagnosis of neonatal erythroderma with a case report of Omenn syndrome.","authors":"Mateja Starbek Zorko, Ana Štublar Krašovec, Vlasta Dragoš","doi":"","DOIUrl":"","url":null,"abstract":"Diagnosing and treating neonatal and infantile erythroderma can be challenging due to the wide variety of potential causes. Neonatal erythroderma is rare and is associated with a high mortality rate due to complications of erythroderma itself and potential life-threatening underlying diseases. Prolonged erythroderma should always be a warning sign and an indication for referral to a hospital where a multidisciplinary team approach is possible. The role of a pediatric dermatologist is to keep in mind the wide spectrum of differential diagnoses that could be causing the condition and the determination of the final diagnosis. To avert a delay in establishing the correct diagnosis, we suggest adhering to specific guidelines. We reviewed available guidelines and adapted a step-by-step approach for use in Slovenia. We also discuss a case of a neonate with erythroderma to illustrate the applicability of the proposed guidelines. Our patient presented with persistent erythroderma, pustules on the trunk and limbs, and intertriginous dermatitis. Despite local corticosteroid treatment, the skin redness persisted. After the exclusion of a systemic infection and additional tests, Omenn syndrome was diagnosed as the underlying cause.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 2","pages":"57-61"},"PeriodicalIF":1.2,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9695891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral postbiotics derived from Lactobacillus sp. in treatment of atopic dermatitis: a meta-analysis. 从乳杆菌中提取的口服后生物制剂治疗特应性皮炎:一项荟萃分析。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-06-01 DOI: 10.15570/actaapa.2023.9

Natalia Tanojo, I. Citrashanty, B. Utomo, Y. Listiawan, Evy Ervianti, Damayanti, Sawitri, Acta Dermatovenerologica, Adriatica Acta, D. Apa

{"title":"Oral postbiotics derived from Lactobacillus sp. in treatment of atopic dermatitis: a meta-analysis.","authors":"Natalia Tanojo, I. Citrashanty, B. Utomo, Y. Listiawan, Evy Ervianti, Damayanti, Sawitri, Acta Dermatovenerologica, Adriatica Acta, D. Apa","doi":"10.15570/actaapa.2023.9","DOIUrl":"https://doi.org/10.15570/actaapa.2023.9","url":null,"abstract":"INTRODUCTION\u0000The use of postbiotics, which are defined as dead microorganisms and/or their components that provide health benefits to the target host, has been shown to reduce the severity of atopic dermatitis (AD) in several studies.\u0000\u0000\u0000METHODS\u0000A systematic literature review was conducted in Pubmed, the Cochrane Library, Science Direct, Clinicaltrials.gov, and Google Scholar, covering the period from January 2012 to July 2022 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. AD patients of all ages that received oral postbiotics or placebo as treatment were the focus of the study. The main study outcome was the scoring of atopic dermatitis (SCORAD) and other measures, such as extension area, disease intensity, and adverse events. The final data were pooled using a fixed-effect model.\u0000\u0000\u0000RESULTS\u0000A meta-analysis of three studies found that, compared to placebo, SCORAD was lower in subjects that were given oral postbiotics from Lactobacillus sp. (mean difference: -2.90, 95% confidence interval [CI; -4.21, -1.59], p < 0.00001). From the comparison of two studies, the differences in disease extension (mean difference: -2.40, 95% CI [-7.67, 2.81], p = 0.37) and intensity (mean difference: -0.27, 95% CI [-0.84, 0.30], p = 0.36) were not significant.\u0000\u0000\u0000CONCLUSIONS\u0000The administration of oral postbiotics from Lactobacillus sp. has the potential to alleviate the severity of AD as indicated by a reduction in SCORAD scores.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 1","pages":"41-47"},"PeriodicalIF":1.2,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85192202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tinea genitalis profunda, a diagnostic challenge: a case report and literature review. 生殖器深癣，一个诊断挑战:一个病例报告和文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-06-01 DOI: 10.15570/actaapa.2023.14

Maruša Selan, B. Hrvatin Stancic, M. Dolenc-Voljč

{"title":"Tinea genitalis profunda, a diagnostic challenge: a case report and literature review.","authors":"Maruša Selan, B. Hrvatin Stancic, M. Dolenc-Voljč","doi":"10.15570/actaapa.2023.14","DOIUrl":"https://doi.org/10.15570/actaapa.2023.14","url":null,"abstract":"Tinea genitalis is a relatively new entity of dermatophyte infection, observed mainly in young adults. By definition, it is localized on the mons pubis and on the labia in women, and on the penile shaft in men. It has been described as a \"lifestyle disease\" and potentially sexually transmitted disease. We report the case of a 35-year-old patient, an immigrant woman, with tinea genitalis profunda, presenting with painful deep infiltrative papules and plaques, purulent inflammation, and signs of secondary impetiginization. Concomitantly, tinea corporis, tinea faciei, tinea colli, and tinea capitis were diagnosed. Her skin lesions developed over an approximately 2-month period. The zoophilic dermatophyte Trichophyton mentagrophytes was cultivated from the pubogenital lesions, as well as Escherichia coli and Klebsiella pneumoniae. The patient was treated systemically with terbinafine, antibiotics, and short-term corticosteroid, and topically with antimycotic and antibiotic cream. During almost 3 weeks of hospitalization, satisfactory improvement was achieved. A literature review with new clinical and epidemiological observations is presented for this rare type of tinea, which poses a diagnostic and treatment challenge.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"35 1","pages":"71-74"},"PeriodicalIF":1.2,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91301888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erythema exudativum multiforme-like exanthema in a patient with Q fever: a case report and literature review. Q热并发多形性渗出性红斑1例并文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-06-01

Nika Jutraž, Borut Žgavec, Violeta Hosta, Svjetlana Ponorac

引用次数: 0

Exanthematous lichen planus in a child and Mycoplasma pneumoniae: a case report and literature review. 儿童扁平苔疹伴肺炎支原体:1例报告并文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-06-01

Olga Točkova, Marija Boljanović, Borut Žgavec, Svjetlana Ponorac

引用次数: 0

Serum survivin in acne versus post-acne scarring and the possible effect of isotretinoin therapy on its level. 痤疮患者血清生存素与痤疮后瘢痕形成及异维甲酸治疗对其水平的可能影响。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-03-01 DOI: 10.15570/actaapa.2023.2

T. Hussein, Nourane Tawfik Abdelsalam Tawfik, Mennatullah Mohamed Abbas Abd-Rabboh, Alsayeda A A Taha

{"title":"Serum survivin in acne versus post-acne scarring and the possible effect of isotretinoin therapy on its level.","authors":"T. Hussein, Nourane Tawfik Abdelsalam Tawfik, Mennatullah Mohamed Abbas Abd-Rabboh, Alsayeda A A Taha","doi":"10.15570/actaapa.2023.2","DOIUrl":"https://doi.org/10.15570/actaapa.2023.2","url":null,"abstract":"INTRODUCTION Acne vulgaris is a common chronic inflammatory disorder of the pilosebaceous unit. Survivin is an apoptosis inhibitor protein, and it contributes crucially to cell cycle regulation. This study measures the serum level of survivin in acne and post-acne scarring patients, and assesses the possible effect of isotretinoin therapy on its level. METHODS Sixty participants, including 40 acne patients (Group IA, IB), and 20 age- and sex-matched controls (Group II) were included. Group IA included 20 patients with active moderate-to-severe acne without scarring, and this group was further prescribed oral isotretinoin therapy for 3 months. Group IB included 20 patients with post-acne scarring of a duration not more than 6 months, without evident active acne lesions. Serum survivin levels were measured in the three groups using an enzyme-linked immunosorbent assay. RESULTS There was a statistically significant higher serum survivin level in the acne scar group, followed by the active acne group, than in controls. In addition, there was a statistically significant reduction in survivin levels after treatment, and it was positively correlated with a reduction in the global acne grading system (GAGS) in the active acne group. CONCLUSIONS Survivin may play a role in the evolution of acne and acne scarring, and it could be a possible target for isotretinoin therapy.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"58 1","pages":"7-10"},"PeriodicalIF":1.2,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85093976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermoscopy: the ultimate tool for diagnosis of nail psoriasis? A review of the diagnostic utility of dermoscopy in nail psoriasis. 皮肤镜检查:指甲银屑病的终极诊断工具?皮肤镜检查在甲癣诊断中的应用综述。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-03-01 DOI: 10.15570/actaapa.2023.3

A. Yorulmaz

{"title":"Dermoscopy: the ultimate tool for diagnosis of nail psoriasis? A review of the diagnostic utility of dermoscopy in nail psoriasis.","authors":"A. Yorulmaz","doi":"10.15570/actaapa.2023.3","DOIUrl":"https://doi.org/10.15570/actaapa.2023.3","url":null,"abstract":"Dermoscopy is a highly practical noninvasive diagnostic tool. Several dermoscopic algorithms have been proposed in the evaluation of skin diseases, which allow clinicians not only to identify and make differential diagnosis, but also to determine the treatment choices in challenging clinical circumstances. Over the years, we have witnessed a rapid increase in the utilization of dermoscopy in the assessment of nail disorders. However, to assess the diagnostic utility of dermoscopy in inflammatory nail diseases, current evidence is insufficient. Nail psoriasis is a significant challenge because of the difficulties in its diagnosis. Detection of nail involvement is of utmost importance in psoriasis because it is highly associated with arthritis, which is an indication for systemic treatment. Dermoscopy holds promise as a potential tool in the diagnosis of nail psoriasis, capable of providing characteristic clinical findings without any delay and discomfort. This review summarizes current evidence regarding the unique dermoscopic features of nail psoriasis. It addresses whether dermoscopy may serve as the gold-standard diagnostic tool, excluding the necessity of histopathological examination for the ultimate diagnosis of nail psoriasis.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"12 1","pages":"11-15"},"PeriodicalIF":1.2,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89531268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Primary biliary cholangitis-cause or association with psoriasis: a case report. 原发性胆道胆管炎与牛皮癣相关:1例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-03-01 DOI: 10.15570/actaapa.2023.6

Patricija Tomše, Valerija Balkovec

{"title":"Primary biliary cholangitis-cause or association with psoriasis: a case report.","authors":"Patricija Tomše, Valerija Balkovec","doi":"10.15570/actaapa.2023.6","DOIUrl":"https://doi.org/10.15570/actaapa.2023.6","url":null,"abstract":"Primary biliary cholangitis is a chronic progressive cholestatic granulomatous and destructive inflammatory lesion of small intralobular and septal bile ducts that primarily affects women. The exact etiology of this disease has not yet been elucidated; however, it is believed to be the result of a combination of environmental triggers in genetically predisposed individuals. It can manifest itself simultaneously with, before, or after the onset of psoriasis and other skin autoimmune diseases. Standard treatment is ursodeoxycholic acid. A 65-year-old patient presenting with elevated hepatic laboratory findings that had persisted for several years and normal abdominal ultrasound was additionally diagnosed with primary biliary cholangitis after 2 years on a biological drug for psoriasis. She did not have other symptoms except elevated liver tests. The skin showed a strong response to biological therapy and treatment with ursodeoxycholic acid prompted lowering of liver enzymes. The skin was clear all throughout the treatment. This article emphasizes the importance of additional diagnostic workups in patients with psoriasis and elevated hepatic laboratory findings.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"58 1","pages":"23-26"},"PeriodicalIF":1.2,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77180648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Treatment of periorbital syringomas with intradermal botulinum toxin A monotherapy versus carbon dioxide laser: a case report. 皮内肉毒杆菌毒素A单药治疗与二氧化碳激光治疗眼眶周围注射器瘤1例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-03-01 DOI: 10.15570/actaapa.2023.4

Sheila Hustadi Budiawan, A. Arimuko, L. Norawati, A. Madjid, W. Widita

引用次数: 0