Acta Dermatovenerologica Alpina Pannonica et Adriatica最新文献_第9页

Safety and efficacy of intralesional injection of enalapril versus triamcinolone acetonide in the treatment of keloids 病灶内注射依那普利与曲安奈德治疗瘢痕疙瘩的安全性和有效性比较

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.16

Basma Hamada Mohamed, Samar Eltahlawy, Walaa Ahmed Marzouk, Noha E. Mohamad

{"title":"Safety and efficacy of intralesional injection of enalapril versus triamcinolone acetonide in the treatment of keloids","authors":"Basma Hamada Mohamed, Samar Eltahlawy, Walaa Ahmed Marzouk, Noha E. Mohamad","doi":"10.15570/actaapa.2023.16","DOIUrl":"https://doi.org/10.15570/actaapa.2023.16","url":null,"abstract":"Keloids are pathologic conditions characterized by fibroblast hyper-proliferation and excess collagen deposition. Enalapril, one of the angiotensin-converting enzyme inhibitors, has recently been highlighted as a new therapeutic modality in treating keloids. This study evaluates the effectiveness of intralesional injection of enalapril versus triamcinolone acetonide (TAA) in keloids.Forty patients with multiple keloids were enrolled in our study. Enalapril and TAA were injected intralesionally in one session per month for three sessions. The clinical outcomes were assessed via the Vancouver Scar Scale (VSS) and the Patient and Observer Scar Assessment Scale (POSAS).In both groups, according to VSS and POSAS, there was a high statistically significant difference (p-value ≤ 0.01) before treatment, at the end of each session, and 3 months after treatment. There was no significant difference between both groups regarding degree of improvement. Patients treated with TAA developed more significant complications than those in the enalapril group (p-value < 0.05).Both enalapril and TAA had the same clinical effect. Enalapril could be a safe alternative to steroids in the treatment of keloid and hypertrophic scars. Further studies on enalapril are needed on a large sample of patients with further focus on the mechanism of this innovative drug.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Swelling of inguinal lymph nodes in a patient with HIV: a case report HIV患者腹股沟淋巴结肿大1例报告

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.23

Mark Sergej Bartenjev, Maja Mastnak, Darja Keše, Andreja Murnik Rauh

引用次数: 0

Colocalizing paraneoplastic alopecia areata and nodular basal cell carcinoma 副肿瘤性斑秃和结节性基底细胞癌的共定位

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.24

Martina Lambertini, Costantino Ricci, Bor Hrvatin Stancic, Martina Mussi, Barbara Corti, Cosimo Misciali, Bianca Maria Piraccini, Emi Dika

引用次数: 0

HIV-1 subtype diversity and phylogenetic insight into non-B subtype transmission in Slovenia, 1989-2013 1989-2013年斯洛文尼亚HIV-1亚型多样性和非b亚型传播的系统发育观察

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.20

Jana Mlakar, Maja M. Lunar, Ana B. Abecasis, Anne-Mieke Vandamme, Janez Tomažič, Tomaž D. Vovko, Blaž Pečavar, Gabriele Turel, Mario Poljak

{"title":"HIV-1 subtype diversity and phylogenetic insight into non-B subtype transmission in Slovenia, 1989-2013","authors":"Jana Mlakar, Maja M. Lunar, Ana B. Abecasis, Anne-Mieke Vandamme, Janez Tomažič, Tomaž D. Vovko, Blaž Pečavar, Gabriele Turel, Mario Poljak","doi":"10.15570/actaapa.2023.20","DOIUrl":"https://doi.org/10.15570/actaapa.2023.20","url":null,"abstract":"Disease progression, drug resistance mutations, and treatment strategies may vary by HIV-1 subtype. This study determined HIV-1 subtypes circulating in Slovenia, a Central European country with an HIV-1 epidemic driven by men who have sex with men, focusing on molecular epidemiology of non-B subtypes.A total of 367 HIV-1 sequences were included. Subtype was assigned by employing eight different HIV subtyping tools coupled with maximum likelihood phylogenetic analyses.The subtyping tools COMET, jpHMM, and REGA 3.0 exhibited the best performance on the dataset studied. Phylogenetic analyses showed a 14.7% prevalence of non-B subtypes, with subtype A detected most frequently (4.9%), followed by CRF02_AG (2.4%), subtype C (1.1%), subtypes D, G, and CRF01_AE (0.8% each), and subtypes F and CRF22_01A1 (0.3% each). A subtype could not be assigned to 12 sequences (3.3%), indicating potential unique recombinant forms. Non-B subtypes were significantly associated with a heterosexual route of transmission and infection acquired in Eastern Europe, Africa, or Asia.In a country where subtype B is predominant, non-B subtypes were observed in one out of seven patients, a non-negligible proportion, which underlines the importance of systematic surveillance of HIV subtype diversity and the corresponding molecular epidemiology.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thirty years of Acta Dermatovenerologica Alpina Pannonica et Adriatica: from the journal’s beginnings to an impact factor 《亚得里亚海皮肤病性病学报》三十年:从期刊创刊到影响因子

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.15

Jovan Miljković, Anja Šterbenc

引用次数: 0

Molecular epidemiology of the 2022 monkeypox virus outbreak in Slovenia 斯洛文尼亚2022年猴痘病毒暴发的分子流行病学

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.21

Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Nataša Knap, Alen Suljič, Tomaž Mark Zorec, Maja Mastnak, Miroslav Petrovec, Mario Poljak, Misa Korva, Tatjana Avšič-Županc

{"title":"Molecular epidemiology of the 2022 monkeypox virus outbreak in Slovenia","authors":"Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Nataša Knap, Alen Suljič, Tomaž Mark Zorec, Maja Mastnak, Miroslav Petrovec, Mario Poljak, Misa Korva, Tatjana Avšič-Županc","doi":"10.15570/actaapa.2023.21","DOIUrl":"https://doi.org/10.15570/actaapa.2023.21","url":null,"abstract":"Monkeypox virus (MPXV), typically endemic in West and Central Africa, has raised global concern due to the recent outbreak in several non-endemic countries with human-to-human transmission. Here we present a comprehensive analysis of MPXV genomes from Slovenia.Two real-time polymerase chain reaction (RT-PCR) assays for Orthopoxvirus (OPV) and MPXV genes were used for laboratory confirmation of mpox. Complete MPXV genomic sequences were obtained using nanopore long reads and Illumina technology. Phylogenetic analyses compared the Slovenian MPXV sequences with the global sequences.A total of 49 laboratory-confirmed mpox cases were diagnosed in Slovenia in 2022, mainly affecting males under 40. In 48 cases, a complete genome sequence was obtained and phylogenetic analysis revealed five distinct lineages (B.1, B.1.14, B.1.2, B.1.3, and A.2.1), with B.1 and B.1.3 dominating, suggesting multiple introductions into Slovenia. Genome analysis revealed significant divergence from the reference MPXV-M5312_HM12_Rivers.The genetic diversity observed in the Slovenian MPXV sequences sheds light on the complex dynamics of the 2022 mpox outbreak and highlights the need for further research to understand the impact of mutations on MPXV functional characteristics and their role in the evolution and diversification of current lineages.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the incidence of anogenital warts and serological test results for other sexually transmitted infections 肛门生殖器疣发病率及其他性传播感染血清学检测结果分析

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.17

Neşe Göçer Gürok

{"title":"Analysis of the incidence of anogenital warts and serological test results for other sexually transmitted infections","authors":"Neşe Göçer Gürok","doi":"10.15570/actaapa.2023.17","DOIUrl":"https://doi.org/10.15570/actaapa.2023.17","url":null,"abstract":"Anogenital warts (AGWs) are proliferative lesions mainly presenting in the anal, genital, and perianal regions. They are one of the most prevalent sexually transmitted infections globally.The study included patients that presented at the Dermatology Clinic of Health Sciences, University Elaziğ, Fethi Sekin City Hospital between January 2019 and December 2022 and were diagnosed with AGWs. Patients that presented with this diagnosis and were screened for other sexually transmitted infections (HBsAg, anti-HBs, anti-HCV, anti-HIV, VDRL, and TPHA) were identified. Epidemiological and demographic patient data and the results of serological tests for other sexually transmitted infections in the last 4 years were analyzed. The patient data and examination results were collected retrospectively based on the hospital automated patient records.AGW incidence was significantly higher in males. The mean patient age was 32, and the mean female patient age was lower than that of males. It was observed that the number of patients that were followed up with an AGW diagnosis increased significantly during the last 4 years (p < 0.05). The study detected 2.2% HBsAg, 0.6% TPHA, 0.3% VDRL, 0.5% anti-HCV, and 56.5% anti-HBs positivity. No anti-HIV-positive patients were identified. None of the patients had more than one sexually transmitted infection on serology testing.Although the serological findings were higher when compared to certain studies and quite low when compared to others, it would be beneficial to evaluate all patients with AGWs for other sexually transmitted infections.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positivity of celiac disease–specific antibodies and non-celiac hypersensitivity in psoriasis 牛皮癣患者乳糜泻特异性抗体阳性和非乳糜泻超敏反应

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-01-01 DOI: 10.15570/actaapa.2023.18

Marina Vekić-Mužević, Lucija Tomić, Nives Pondeljak, Elvira Lazić Mosler

{"title":"Positivity of celiac disease–specific antibodies and non-celiac hypersensitivity in psoriasis","authors":"Marina Vekić-Mužević, Lucija Tomić, Nives Pondeljak, Elvira Lazić Mosler","doi":"10.15570/actaapa.2023.18","DOIUrl":"https://doi.org/10.15570/actaapa.2023.18","url":null,"abstract":"Plaque psoriasis and celiac disease are multisystemic diseases. The association of psoriasis and enteropathy with histological changes similar to celiac disease has already been described, and it has also been found that a gluten-free diet improves psoriatic changes. This study assesses the relationship between celiac disease antibodies and psoriasis.The study included 112 participants: 60 with psoriasis in a test group and 52 healthy subjects in a control group. Within the psoriasis group, participants were further divided into two subgroups: one consisting of patients with both psoriasis and psoriatic arthritis (n = 17) and another comprising patients with psoriasis alone (n = 43). After informed consent was obtained, the Dermatology Life Quality Index (DLQI) score and Psoriasis Area and Severity Index (PASI) score were evaluated. Laboratory tests included assessment of anti-deaminated gliadin peptide antibodies (DGP), anti-gliadin antibodies (AGA), and anti-tissue transglutaminase antibodies (tTG).Immunoglobulin G (IgG) and immunoglobulin A (IgA) DGP antibodies were detected more frequently and at higher serum concentrations in patients with psoriasis compared to healthy controls (p = 0.03, p = 0.04, respectively). Similarly, elevated levels of IgG-tTG antibodies (p = 0.003) and IgA-DGP antibodies (p = 0.02) were observed in the same test group.A relationship between positivity to celiac disease antibodies and psoriasis, particularly with regard to AGA, has been identified. Further studies are required to elucidate the nature, pathophysiology, and significance of these findings.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135700532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic radiation dermatitis induced by cardiac catheterization: a case report and literature review. 心导管置管诱发慢性放射性皮炎1例并文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2022-12-01 DOI: 10.15570/actaapa.2022.25

Ting-Ting Cheng, Hui-Ju Yang

引用次数: 0

A diagnostic challenge in an atypical variant of microcystic adnexal carcinoma mimicking ulcerative basal cell carcinoma: a case report and brief literature review. 模拟溃疡性基底细胞癌的微囊性附件癌的非典型变异的诊断挑战:一个病例报告和简短的文献复习。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2022-12-01

Nurul Indah Pratiwi, Khairuddin Djawad, Jonathan Kurnia Wijaya, Mahmud Ghaznawie, Siswanto Wahab, Airin Nurdin

{"title":"A diagnostic challenge in an atypical variant of microcystic adnexal carcinoma mimicking ulcerative basal cell carcinoma: a case report and brief literature review.","authors":"Nurul Indah Pratiwi, Khairuddin Djawad, Jonathan Kurnia Wijaya, Mahmud Ghaznawie, Siswanto Wahab, Airin Nurdin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Microcystic adnexal carcinoma (MAC) is a rare adnexal tumor with eccrine and pillar differentiations with a localized and aggressive nature, often misdiagnosed as other dermatoses. The most common clinical manifestations of MAC are yellowish or skin-colored papules, nodules, and plaques. However, in some rare cases an atypical manifestation such as ulceration that resembles malignancies such as basal cell carcinoma (BCC) can also occur. Diagnosis of MAC mainly relies on the aid of histopathology. Due to potential infiltration to other structures such as in perineural invasion, wide surgical excision or Mohs micrographic surgery is the preferred surgical option. We report the case of a 75-year-old male patient with ulcerative lesion on the forehead that clinically resembled BCC in addition to typical dermoscopic findings of BCC. However, histopathology confirmed a diagnosis of MAC, prompting physicians to be more aware of this condition when encountering chronic ulcerative lesions. After wide excision and a 1-year follow-up, the patient exhibited no signs of recurrences and will continue long-term follow-up.</p>","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"31 4","pages":"151-155"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0