Case Reports in Otolaryngology最新文献_第5页

Combination Immunosuppressive Therapy in Primary Autoimmune Inner Ear Disease in Pregnancy 联合免疫抑制治疗妊娠期原发性自身免疫性内耳疾病

IF 0.6

Case Reports in Otolaryngology Pub Date : 2022-03-18 DOI: 10.1155/2022/9210780

Saikrishna Ananthapadmanabhan, J. Jabbour, David Brown, V. Sivapathasingam

{"title":"Combination Immunosuppressive Therapy in Primary Autoimmune Inner Ear Disease in Pregnancy","authors":"Saikrishna Ananthapadmanabhan, J. Jabbour, David Brown, V. Sivapathasingam","doi":"10.1155/2022/9210780","DOIUrl":"https://doi.org/10.1155/2022/9210780","url":null,"abstract":"Objective Autoimmune inner ear disease (AIED) is a rare disorder characterized by rapidly progressive, sensorineural hearing loss that demonstrates good responsiveness to corticosteroid and immunosuppressive therapy. The pathophysiology is likely driven by chronic trafficking of immune cells into the inner ear, targeting inner ear proteins to coordinate inflammation. Suppression or modulation of the immune response can minimize cochleitis allowing for potential recovery of hearing. It is an otologic emergency requiring a multidisciplinary approach to management to commence immunosuppressive therapy. This can be achieved using steroids, immunomodulators, plasmapheresis, intravenous immunoglobulin, or biologic agents. Treatment decisions are further complicated in pregnancy and require supervision by an obstetrician and maternal-fetal medicine (MFM) specialist. Concerns include safe dosing of steroids and potential for transplacental migration of immune complexes. We provide the first comprehensive literature review on AIED and its implications in pregnancy. We frame our discussion in the context of the second reported case of primary AIED in pregnancy and the first to show excellent response to immunosuppressive therapy. Methods We reviewed the presented case and literature on AIED. Results A 27-year-old, pregnant, HSP-70 positive woman was diagnosed with AIED and had excellent recovery of hearing and balance following a combination of steroid treatment, augmented by oral immunomodulators, plasmapheresis, and IVIG. Conclusion AIED is a diagnostic challenge, and treatment considerations are complex when encountered in pregnancy. Management requires multidisciplinary involvement between otolaryngologists, immunologists, and obstetricians to balance maternal and fetal health outcomes.","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"5 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85010195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent Stapedial Artery Encountered during Cochlear Implantation 人工耳蜗植入过程中遇到持续性镫骨动脉

IF 0.6

Case Reports in Otolaryngology Pub Date : 2022-02-22 DOI: 10.1155/2022/8179062

H. Jones, J. Hintze, A. Gendre, C. Wijaya, F. Glynn, L. Viani, P. Walshe

引用次数: 1

Ipsilateral Vestibular Schwannoma after Cochlear Implantation 人工耳蜗植入术后同侧前庭神经鞘瘤

IF 0.6

Case Reports in Otolaryngology Pub Date : 2022-02-18 DOI: 10.1155/2022/4918785

S. Tüpker, N. Ay, L. Scholtz, H. Gehl, V. Mautner, P. Goon, H. Sudhoff, I. Todt

{"title":"Ipsilateral Vestibular Schwannoma after Cochlear Implantation","authors":"S. Tüpker, N. Ay, L. Scholtz, H. Gehl, V. Mautner, P. Goon, H. Sudhoff, I. Todt","doi":"10.1155/2022/4918785","DOIUrl":"https://doi.org/10.1155/2022/4918785","url":null,"abstract":"Objective The vestibular schwannoma incidence rate is approximately 4.2 per 100,000/year. Thus far, about 700,000 cochlear implantations have been performed worldwide; therefore, the occurrence of vestibular schwannoma postcochlear implantations can be assumed to be infrequent. Recent developments allow safe observation and surveillance of the implanted-side internal auditory canal (IAC) and cochlea by magnetic resonance imaging (MRI), even after cochlear implantation. Patients. A 71-year-old woman with sudden hearing loss and a contralateral vestibular schwannoma without clinical and genetic signs of neurofibromatosis type II. Intervention(s). Ipsilateral cochlear implantation and contralateral vestibular schwannoma extirpation with regular tumor follow-up. Main Outcome Measure(s). Comparison of ipsilateral pre and postcochlear implantation 3T MRI T1 GAD. Results We observed a tumor growing at the fundus of the internal auditory canal 1 year after cochlear implantation on the ipsilateral side. Although first detected after cochlear implantation beside a known vestibular schwannoma on the contralateral side, a scan slice thickness of 2 mm cannot fully exclude the preoperative persistence of a small tumor. Based on the clinical findings and after genetic exclusion of NFII, the patient was classified as a NFII mosaic type. Conclusion Even after cochlear implantation, tumors in the IAC causing vertigo, facial palsy, and affecting the audiologic outcome can be detected by MRI. The MRI slice thickness used before cochlear implantation should be under 2 mm.","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"105 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85893900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coexisting Thyroglossal Duct Cyst with Papillary Thyroid Cancer: A Case Report and Literature Review. 甲状腺舌管囊肿合并甲状腺乳头状癌1例报告并文献复习。

IF 0.6

Case Reports in Otolaryngology Pub Date : 2021-12-26 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6111308

Abdullah A Alarfaj, Ahmed Zekri, Ibrahim Alyaeesh, Ahmed Alomairin, Abdulrahman Al Naim

{"title":"Coexisting Thyroglossal Duct Cyst with Papillary Thyroid Cancer: A Case Report and Literature Review.","authors":"Abdullah A Alarfaj, Ahmed Zekri, Ibrahim Alyaeesh, Ahmed Alomairin, Abdulrahman Al Naim","doi":"10.1155/2021/6111308","DOIUrl":"https://doi.org/10.1155/2021/6111308","url":null,"abstract":"Thyroglossal duct cysts (TGDCs) are common developmental anomalies in which the thyroglossal duct is not obliterated. Coexisting papillary thyroid cancer and TGDC are uncommon and should be investigated thoroughly to rule out TGDC carcinoma. We report a rare case of coexisting papillary thyroid cancer and TGDC in a 48-year-old man, who presented with a history of recurrent mild painful midline neck swelling, and ultrasound (US) revealed a TGDC that was subsequently managed conservatively. On follow-up after 1.6 years, a thyroid US and a fine-needle aspiration (FNA) biopsy were performed, which showed malignant papillary thyroid carcinoma. Total thyroidectomy, the Sistrunk procedure, and central neck dissection were implemented. After three days, the patient was discharged on 150 mg of levothyroxine. Follow-up was unremarkable with no complications. The authors would like to stress the importance of regular TGDC and thyroid gland follow-ups for early detection and diagnosis of thyroid malignancy via clinical examination and US.","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"6111308"},"PeriodicalIF":0.6,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39788037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed-Onset Neuropathic Pain after Septoplasty. 鼻中隔成形术后的延迟性神经性疼痛。

IF 0.6

Case Reports in Otolaryngology Pub Date : 2021-12-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9966318

Foteini-Stefania Koumpa, Mark Ferguson, Hesham Saleh

引用次数: 0

A Rare Complication of Fine-Needle Aspiration of Neck Structures. 颈部结构细针抽吸的罕见并发症。

IF 0.6

Case Reports in Otolaryngology Pub Date : 2021-12-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8944119

Yazeed M Qadadha, Nainika Nanda, Chad Ennis, Timothy McCulloch

引用次数: 0

Importance of Imaging in Congenital Unilateral Vocal Fold Paralysis: A Case of Neck Neuroblastoma Presenting with Unilateral Vocal Fold Paralysis. 影像学在先天性单侧声带麻痹中的重要性:一例颈部神经母细胞瘤表现为单侧声带麻痹。

IF 0.6

Case Reports in Otolaryngology Pub Date : 2021-12-06 eCollection Date: 2021-01-01 DOI: 10.1155/2021/7368567

W X Yeo, C Y Chan, K K H Tan

引用次数: 0

Bilateral Recurrent Laryngeal Nerve Palsy following Total Thyroidectomy in Triple A Syndrome, an Unexpected but Critical Complication. 全甲状腺切除术后双侧喉返神经麻痹的三重A综合征，一个意想不到的但关键的并发症。

IF 0.6

Case Reports in Otolaryngology Pub Date : 2021-11-19 eCollection Date: 2021-01-01 DOI: 10.1155/2021/1315117

Mathieu Chamberland, Marc-Antoine Poulin, Danielle Beaudoin

引用次数: 0

INI1-Intact Sinonasal Carcinoma with Rhabdoid Features. 完整鼻窦癌伴横纹肌样特征。

IF 0.6

Case Reports in Otolaryngology Pub Date : 2021-11-18 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6075130

Erin Mulry, Danielle M Blake, Poornima Hegde, Todd E Falcone

{"title":"INI1-Intact Sinonasal Carcinoma with Rhabdoid Features.","authors":"Erin Mulry, Danielle M Blake, Poornima Hegde, Todd E Falcone","doi":"10.1155/2021/6075130","DOIUrl":"https://doi.org/10.1155/2021/6075130","url":null,"abstract":"Sinonasal malignancies are known for their associated poor prognosis and diversity of histologic features. While poor prognosis is largely due to advanced disease at presentation, histologic features also play a significant role. Therefore, accurate pathologic diagnosis is of utmost importance. Here, we describe a 63-year-old male with chronic left-sided nasal obstruction and left-sided epistaxis who was found to have a large mass occupying most of the nasal cavity extending through the nasopharynx to just below the nasopharyngeal surface of the soft palate. During surgical excision, the mass was noted to originate from the floor of the maxillary sinus with erosion of the medial wall of the maxillary sinus. Pathology revealed a diagnosis of INI1-intact poorly differentiated composite carcinoma with rhabdoid phenotype and sarcomatoid and squamous cell carcinoma foci arising within an inverted papilloma. Included in this report is a detailed description of both the patient's medical course and this pathologically novel sinonasal neoplasm. We aim to elucidate this rare tumor's complex features in order to improve future diagnosis and stimulate prospective research on sinonasal malignancies with complex histology.","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"6075130"},"PeriodicalIF":0.6,"publicationDate":"2021-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39763167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ALK-Positive Anaplastic Large Cell Lymphoma: A Diagnostic Dilemma for the Otolaryngologist in a Resource Poor Setting. alk阳性间变性大细胞淋巴瘤:一个诊断困境的耳鼻喉科医生在资源贫乏的设置。

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Case Reports in Otolaryngology Pub Date : 2021-11-01 eCollection Date: 2021-01-01 DOI: 10.1155/2021/3756742

Nicholas Figaro, Rickhi Ramoutar, Rodolfo Arozarena, Dawn Meyers, Solaiman Juman

引用次数: 0