Case Reports in Otolaryngology最新文献

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Seromucinous Hamartoma of the Lateral Nasal Wall with Infiltration of the Orbit: A Rare Case Report and Review of the Literature. 鼻侧壁浆液黏液错构瘤伴眼眶浸润一例罕见病例报告及文献复习。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/1923015
Lentiona Basiari, Maria Michali, Ioannis Komnos, Georgios Tsirves, Victoria Tsoumani, Ioannis Kastanioudakis
{"title":"Seromucinous Hamartoma of the Lateral Nasal Wall with Infiltration of the Orbit: A Rare Case Report and Review of the Literature.","authors":"Lentiona Basiari,&nbsp;Maria Michali,&nbsp;Ioannis Komnos,&nbsp;Georgios Tsirves,&nbsp;Victoria Tsoumani,&nbsp;Ioannis Kastanioudakis","doi":"10.1155/2023/1923015","DOIUrl":"https://doi.org/10.1155/2023/1923015","url":null,"abstract":"<p><p>Seromucinous hamartoma is a rare benign glandular proliferation arising from the respiratory epithelium of the sinonasal tract and nasopharynx. It was described for the first time in 1974 by Baillie and Batsakis. Since then, few cases have been reported in the literature with most of them occurring in the posterior nasal septum. We report the case of a 52-year-old woman that presented to our department with left periorbital edema, pain, and dacryorrhea due to seromucinous hamartoma arising from the left inferior turbinate and extending through the lateral nasal wall into the maxilla, the nasolacrimal duct, and the orbit. Endoscopic medial maxillectomy and endoscopic transnasal orbital tumor resection were performed. The patient remains symptom-free for 16 months, till her most recent follow-up. Seromucinous hamartoma of the nasal cavity is an exceedingly rare diagnosis, especially in the lateral nasal wall. It should be included in the differential diagnosis of nasal tumors. According to the literature review, this is the first case report of seromucinous hamartoma with orbit infiltration. Endonasal endoscopic resection is the treatment of choice.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"1923015"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10406194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transnasal Endoscopic Treatment of Tension Pneumocephalus Caused by Posttraumatic or Iatrogenic Ethmoidal Damage. 经鼻内镜治疗创伤后或医源性筛损伤所致张力性脑气。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/2679788
Goran Latif Omer, Riccardo Maurizi, Beatrice Francavilla, Kareem Rekawt Hama Rashid, Gianluca Velletrani, Hasan Mustafa Salah, Giulia Marzocchella, Mohammed Ibrahim Mohialdeen Gubari, Stefano Di Girolamo
{"title":"Transnasal Endoscopic Treatment of Tension Pneumocephalus Caused by Posttraumatic or Iatrogenic Ethmoidal Damage.","authors":"Goran Latif Omer,&nbsp;Riccardo Maurizi,&nbsp;Beatrice Francavilla,&nbsp;Kareem Rekawt Hama Rashid,&nbsp;Gianluca Velletrani,&nbsp;Hasan Mustafa Salah,&nbsp;Giulia Marzocchella,&nbsp;Mohammed Ibrahim Mohialdeen Gubari,&nbsp;Stefano Di Girolamo","doi":"10.1155/2023/2679788","DOIUrl":"https://doi.org/10.1155/2023/2679788","url":null,"abstract":"<p><strong>Background: </strong>Tension pneumocephalus is a neurosurgical emergency caused by progressive accumulation of air in the intracranial spaces mediated by a valve mechanism. Tension pneumocephalus usually presents with headaches, reduced consciousness, and even death. One of the most common causes is an ethmoidal defect resulted by nasal surgery or facial traumas.</p><p><strong>Methods: </strong>A literature review about tension pneumocephalus resulting from ethmoidal damages was performed. Surgery strategies included decompression by frontal burr holes and multilayer repair of the ethmoidal defect. In this paper, an endoscopic technique that exploits the ethmoidal defect to decompress the intracranial spaces and to resolve tension pneumocephalus with fewer complications and shorter hospitalization in comparison to frontal craniotomy is proposed.</p><p><strong>Conclusion: </strong>The proposed endonasal endoscopic technique could be effectively used as a first-line treatment for symptomatic tension pneumocephalus caused by posttraumatic or iatrogenic ethmoidal defect.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"2679788"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10127460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Laryngeal Cryptococcosis that Responded to Itraconazole. 伊曲康唑治疗喉隐球菌病1例。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/8847838
Sorane Maezumi, Ray Motohashi, Yusuke Shoji, Kiyoaki Tsukahara
{"title":"A Case of Laryngeal Cryptococcosis that Responded to Itraconazole.","authors":"Sorane Maezumi,&nbsp;Ray Motohashi,&nbsp;Yusuke Shoji,&nbsp;Kiyoaki Tsukahara","doi":"10.1155/2023/8847838","DOIUrl":"https://doi.org/10.1155/2023/8847838","url":null,"abstract":"<p><p>Laryngeal cryptococcosis is a rare condition. While there is no reliable evidence regarding the treatment of laryngeal cryptococcosis, oral fluconazole was successful in most previous cases. We experienced a case where we could not continue fluconazole because of adverse drug effects. An 88-year-old female was referred to our department with a 5-month history of sore throat and cough. She had used oral steroids and a corticosteroid inhaler for poorly controlled asthma. Flexible laryngoscopy showed leukoplakia of the vocal cords and subglottic mucosa, and biopsy revealed cryptococcal infection. We started the treatment with fluconazole but changed to itraconazole because of adverse events. Since laryngoscopy performed 6 months later was unremarkable and drug interactions had occurred, we stopped the itraconazole use at 6 months. Our experience suggests that itraconazole is also useful for treating laryngeal cryptococcosis.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"8847838"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9756717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clival Defect Resulting in Spontaneous Cerebrospinal Fluid Rhinorrhea: Case Report and Review of Literature. 斜坡缺损致自发性脑脊液鼻漏1例报告及文献复习。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/3205191
Maryam Aljawi, Mahdi Shkoukani
{"title":"Clival Defect Resulting in Spontaneous Cerebrospinal Fluid Rhinorrhea: Case Report and Review of Literature.","authors":"Maryam Aljawi,&nbsp;Mahdi Shkoukani","doi":"10.1155/2023/3205191","DOIUrl":"https://doi.org/10.1155/2023/3205191","url":null,"abstract":"<p><p>Spontaneous cerebrospinal fluid (CSF) rhinorrhea develops in patients without any history of trauma. Multiple factors have been theoretically debated. Also, localizing the defect may result in a challenge for the rhinologist. The common locations are the cribriform plate and the lateral recess of the sphenoid. Clival CSF rhinorrhea is rare, and only few cases have been reported so far. A 52-year-old female presented to the otolaryngology clinic with 7 years of history of left-side clear fluid rhinorrhea as a drop, which progressed to be runnier after she had pneumonia with severe cough secondary to COVID-19 infection. CSF was confirmed by a beta-2-transferrin test. During the perioperative evaluation, she developed meningitis which was treated with IV ceftriaxone and IV vancomycin antibiotics. The magnetic resonance imaging (MRI) and computerized tomography (CT) scan showed clival defect with pseudomeningocele which was initially not easy to see on CT. The patient underwent an endoscopic approach to the skull base to repair the defect with a pedicled septal flap. Also, a lumbar drain with intrathecal fluorescein administration was utilized. The postoperative course was uneventful without any complications. There was no evidence of recurrence with a 9-month follow-up postoperatively.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"3205191"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9926001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case Report of Thyroglossal Duct Cyst Carcinoma Coexisting with Thyroid Carcinoma in an Adolescent. 青少年甲状腺舌管囊肿癌合并甲状腺癌1例。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/6640087
Kleanthi Mylopotamitaki, Dionisios Klonaris, Georgios Kazamias, Christos Simandirakis, Irene Vourliotaki, Efthimios Karakostas
{"title":"A Rare Case Report of Thyroglossal Duct Cyst Carcinoma Coexisting with Thyroid Carcinoma in an Adolescent.","authors":"Kleanthi Mylopotamitaki,&nbsp;Dionisios Klonaris,&nbsp;Georgios Kazamias,&nbsp;Christos Simandirakis,&nbsp;Irene Vourliotaki,&nbsp;Efthimios Karakostas","doi":"10.1155/2023/6640087","DOIUrl":"https://doi.org/10.1155/2023/6640087","url":null,"abstract":"<p><strong>Background: </strong>Thyroglossal duct cysts (TDC) represent approximately 70% of all congenital neck masses, and up to 1% of them contain thyroid tissue malignancies. Clinical presentation of TDC carcinomas is usually indistinguishable from benign tumors preoperatively, and differential diagnosis can be challenging. We present a rare case of TDC carcinoma concurrent with thyroid cancer in an adolescent. <i>Case Presentation</i>. A 16-year-old Caucasian female, otherwise healthy, was referred with a painless, gradually expanding lump on the neck. Physical examination revealed a well-circumscribed, moderately hard, tender mass of the anterior neck midline anteroinferior to the hyoid bone. Imaging findings suggested TDC as the most likely diagnosis. The patient had a Sistrunk procedure under general anesthesia. Histopathological findings diagnosed a BRAF<sup>V600E</sup>-positive papillary thyroid carcinoma (PTC) in a TDC. A thyroid gland and neck ultrasound revealed a highly suspicious finding for malignancy right level VI lymph node, which was not confirmed by fine needle aspiration cytology (FNAC). Under general anesthesia, total thyroidectomy and central compartment lymph node neck dissection were performed. Histopathological findings revealed a thyroid parenchymal locus of PTC, as well as three lymph nodes infiltrated by PTC. The patient received adjuvant radioactive iodine ablation (RAI) therapy and is closely followed.</p><p><strong>Conclusion: </strong>TDC carcinomas in conjunction with thyroid carcinomas in young patients are rare. Preoperative diagnosis can be challenging, as the vast majority of neck masses in young patients are benign in nature, and most malignant tumors lack specific clinical features. The diagnostic accuracy of FNAC is considered unsatisfactory due to its frequently cystic nature. Definitive diagnosis is based on histopathological findings. Clinicians should maintain a high level of suspicion for coexisting thyroid malignancies. Although surgical extirpation of the malignancy is considered standard of care, the treatment of TDC cancer should always be individualized by a multidisciplinary team.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"6640087"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10626429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transdural Skull Base Infiltration by Glioblastoma: Case Report and Review of the Literature. 胶质母细胞瘤经硬膜颅底浸润一例报告及文献复习。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/4727288
Michael Thrull, Khaled Atasi, Lennart-Maximilian Boese, Mahmut Cakar, Ullrich Heller, Nils Jansen, Leoni-Christine Menzel, Hassan Omaimen, Katharina Theis, Damir Karacic, Diyan Dimov, Roland Coras, Randolf Klingebiel
{"title":"Transdural Skull Base Infiltration by Glioblastoma: Case Report and Review of the Literature.","authors":"Michael Thrull,&nbsp;Khaled Atasi,&nbsp;Lennart-Maximilian Boese,&nbsp;Mahmut Cakar,&nbsp;Ullrich Heller,&nbsp;Nils Jansen,&nbsp;Leoni-Christine Menzel,&nbsp;Hassan Omaimen,&nbsp;Katharina Theis,&nbsp;Damir Karacic,&nbsp;Diyan Dimov,&nbsp;Roland Coras,&nbsp;Randolf Klingebiel","doi":"10.1155/2023/4727288","DOIUrl":"https://doi.org/10.1155/2023/4727288","url":null,"abstract":"<p><p>We report the rare occurrence of a temporal glioblastoma multiforme (GBM) showing transdural tumor extension into adjacent mastoid cells. As the dura mater provides a barrier to intraaxial tumors, GBM seldom penetrates into the skull base, even though it is a high-grade astrocytoma with a tendency to spread. Yet, some mechanisms of GBM-induced skull invasion have been identified, making this entity a very rare but nonetheless relevant differential diagnosis in otherwise ambiguous cases of an intracerebral tumor extending into the skull base. In addition, imaging markers that may assist in distinguishing extra- from intraaxial tumor infiltration of the temporal bone are described.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"4727288"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soccer and Benign Paroxysmal Positional Vertigo. 足球与良性阵发性位置性眩晕。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/3744863
Nikolaj Warming, Stephanie Balslev Andersen, Dan Dupont Hougaard
{"title":"Soccer and Benign Paroxysmal Positional Vertigo.","authors":"Nikolaj Warming,&nbsp;Stephanie Balslev Andersen,&nbsp;Dan Dupont Hougaard","doi":"10.1155/2023/3744863","DOIUrl":"https://doi.org/10.1155/2023/3744863","url":null,"abstract":"<p><p><i>Introduction</i>. Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo among adults. The etiology of BPPV is unknown in approximately 50 percent of cases. This condition is also termed primary BPPV, if the etiology is unknown, and secondary BPPV if patients have identified predisposing factors. A few studies suggest that there is a correlation between the development of BPPV and specific sports. <i>Case Report</i>. A 19-year-old male presented with recurrent episodes of vertigo during soccer play. Eight months prior to referral, the patient was involved in a car accident with a mild head trauma. The patient was later diagnosed with BPPV several times. <i>Discussion</i>. Soccer might be a plausible BPPV trigger, especially if there is a prehistory of head trauma. This is most likely due to the demands of the game such as the change of directions, repetitive head impacts (headers or head collisions), accelerations/decelerations, jumps, foot landings, and rapid head movements.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"3744863"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10778813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Clinical Impact of Vascular Endothelial Growth Factor/Receptor (VEGF/R) Inhibitors on Voice. 血管内皮生长因子/受体(VEGF/R)抑制剂对声音的临床影响。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/1902876
Christina Hui Lee Ng, Edward J Damrose
{"title":"The Clinical Impact of Vascular Endothelial Growth Factor/Receptor (VEGF/R) Inhibitors on Voice.","authors":"Christina Hui Lee Ng,&nbsp;Edward J Damrose","doi":"10.1155/2023/1902876","DOIUrl":"https://doi.org/10.1155/2023/1902876","url":null,"abstract":"<p><strong>Background: </strong>Vascular endothelial growth factor/receptor (VEGF/R) inhibitors are used in chemotherapy protocols to limit tumor angiogenesis. Recent evidence shows they are associated with hoarseness, but their impact on vocal cord function has not been fully identified.</p><p><strong>Objectives: </strong>To describe the preliminary laryngeal findings in patients undergoing chemotherapy with VEGF/R inhibitors, and to describe possible mechanisms of their effect on vocal fold function.</p><p><strong>Methods: </strong>A retrospective case series was conducted in a tertiary medical center between July 2008 and August 2022. Cancer patients developing hoarseness while undergoing chemotherapy with VEGF/R inhibitors underwent videolaryngostroboscopy.</p><p><strong>Results: </strong>The study included four patients. There were three females and one male, treated for breast, lung, and unknown primary cancer, respectively. All 4 patients developed hoarseness 2-7 days after initiating treatment with the VEGF/R inhibitor drugs aflibercept (<i>n</i> = 1) and bevacizumab (<i>n</i> = 3). In all patients, videolaryngostroboscopy revealed vocal fold bowing and pronounced glottic insufficiency. There were no signs of mucositis or paralysis. In three patients, treatment involved speech therapy, with or without vocal fold augmentation. The average follow-up was 10 months (range 8-12 months). In 2 patients, there was a return of normal voice quality with resolution of vocal fold bowing. In one patient, who remained on chemotherapy, there was persistent bowing.</p><p><strong>Conclusions: </strong>VEGF/R inhibitors are associated with vocal fold bowing and glottic insufficiency. This appears to be a reversible side effect. To our knowledge, this is only the second clinical description of the effect of VEGF/R inhibitors on vocal fold function.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"1902876"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9284173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemotympanum as a Complication of a Valsalva Maneuver during Childbirth. 分娩时Valsalva术并发鼓室积血。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/3328895
Tali Teitelbaum, Isaac Shochat, Golda Grinblat, Mohamad Taha, Itzhak Braverman
{"title":"Hemotympanum as a Complication of a Valsalva Maneuver during Childbirth.","authors":"Tali Teitelbaum,&nbsp;Isaac Shochat,&nbsp;Golda Grinblat,&nbsp;Mohamad Taha,&nbsp;Itzhak Braverman","doi":"10.1155/2023/3328895","DOIUrl":"https://doi.org/10.1155/2023/3328895","url":null,"abstract":"<p><strong>Background: </strong>Hemotympanum may occur due to otic barotrauma secondary to Valsalva maneuver during the second phase of labor. A pressure differential across the tympanic membrane (TM) of about five psi can cause rupture. The increased intrathoracic and intraabdominal pressure spikes repeatedly manifested by \"pushing\" during second-stage labor easily approach (and may exceed) this level. <i>Clinical Presentation</i>. This case report describes a healthy thirty-seven-year-old multipara patient admitted for the 40-weeks' gestational age routine follow-up that proceeded to active labor followed by an aural fullness and bloody otorrhea. Otoscopic examination with a light microscope confirmed the hemotympanum of the right tympanic membrane.</p><p><strong>Conclusion: </strong>Forceful Valsalva can cause hemotympanum. Investigating the benefits and disadvantages of the pushing methods could help reduce such complications in the future. A prompt evaluation of an otolaryngologist should be requested in the event of a new postpartum hearing disturbance or bloody otorrhea.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"3328895"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10045166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lymphoepithelial Carcinoma Originated from the Sinonasal Cavity: Case Report and Literature Review. 起源于鼻腔的淋巴上皮癌:病例报告及文献复习。
IF 0.6
Case Reports in Otolaryngology Pub Date : 2023-01-01 DOI: 10.1155/2023/4217102
Hassan Alhazzani, Saleh Alabood, Ahmed Alhussien, Sahar Alsadah, Abdulrahman Alghulikah, Shuaa Asiri, Ibrahim Alarifi
{"title":"Lymphoepithelial Carcinoma Originated from the Sinonasal Cavity: Case Report and Literature Review.","authors":"Hassan Alhazzani,&nbsp;Saleh Alabood,&nbsp;Ahmed Alhussien,&nbsp;Sahar Alsadah,&nbsp;Abdulrahman Alghulikah,&nbsp;Shuaa Asiri,&nbsp;Ibrahim Alarifi","doi":"10.1155/2023/4217102","DOIUrl":"https://doi.org/10.1155/2023/4217102","url":null,"abstract":"<p><strong>Background: </strong>Sinonasal lymphoepithelial carcinoma (SNLEC) is a rare neoplasm, representing less than 1% of all types of carcinomas and approximately 3% of head and neck tumors. It can affect the nasopharynx due to the rich lymphoid tissue present in this region. Clinical SNLEC presentation varies, ranging from asymptomatic to nonspecific sinonasal symptoms. We report a case of SNLEC and review the literature for SNLEC presentation, diagnosis, management options, and outcomes. <i>Case Presentation</i>. A 38-year-old male, medically free, presented to the emergency department complaining of nasal obstruction, right facial numbness, persistent right-sided headache, intermittent orbital pain, and a history of on/off epistaxis. Imaging showed a destructive mass in the right sphenoid sinus extending to different sinuses and infratemporal fossa. Biopsy confirmed the diagnosis of SNLEC, with immunohistochemistry being positive for Epstein-Barr virus (EBV) and CK8/18. Induction chemotherapy was started with three cycles of cisplatin and gemcitabine, followed by concurrent chemoradiation therapy.</p><p><strong>Conclusion: </strong>SNLEC is rare, with limited reported cases from around the world. It is mostly seen in adults between their fifth and seventh decades with male predominance. SNLEC is diagnosed using imaging, immunohistochemistry, and EBV testing given its strong association with EBV. Owing to the limited cases, there is no standard approach to treating SNLEC. However, most cases managed with radiation and with and without other modalities showed an excellent response in terms of tumor nonrecurrence.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2023 ","pages":"4217102"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9531842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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