Journal of Transplantation最新文献_第10页

Heart transplantation in congenital heart disease: in whom to consider and when? 先天性心脏病的心脏移植:何时考虑谁?

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-02-07 DOI: 10.1155/2013/376027

Christine H Attenhofer Jost, Dörthe Schmidt, Michael Huebler, Christian Balmer, Georg Noll, Rosmarie Caduff, Matthias Greutmann

{"title":"Heart transplantation in congenital heart disease: in whom to consider and when?","authors":"Christine H Attenhofer Jost, Dörthe Schmidt, Michael Huebler, Christian Balmer, Georg Noll, Rosmarie Caduff, Matthias Greutmann","doi":"10.1155/2013/376027","DOIUrl":"https://doi.org/10.1155/2013/376027","url":null,"abstract":"Due to impressive improvements in surgical repair options, even patients with complex congenital heart disease (CHD) may survive into adulthood and have a high risk of end-stage heart failure. Thus, the number of patients with CHD needing heart transplantation (HTx) has been increasing in the last decades. This paper summarizes the changing etiology of causes of death in heart failure in CHD. The main reasons, contraindications, and risks of heart transplantation in CHD are discussed and underlined with three case vignettes. Compared to HTx in acquired heart disease, HTx in CHD has an increased risk of perioperative death and rejection. However, outcome of HTx for complex CHD has improved over the past 20 years. Additionally, mechanical support options might decrease the waiting list mortality in the future. The number of patients needing heart-lung transplantation (especially for Eisenmenger's syndrome) has decreased in the last years. Lung transplantation with intracardiac repair of a cardiac defect is another possibility especially for patients with interatrial shunts. Overall, HTx will remain an important treatment option for CHD in the near future.","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"376027"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/376027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31442859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Transplant coordinators' perceived impact of availability of multiple generic immunosuppression therapies on patients, workload, and posttransplant maintenance therapy. 移植协调员感知到的多种通用免疫抑制疗法对患者、工作量和移植后维持治疗的影响。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-01-08 DOI: 10.1155/2013/897434

K Parker, E A Zagadailov, A S Bruno, A M Wiland

{"title":"Transplant coordinators' perceived impact of availability of multiple generic immunosuppression therapies on patients, workload, and posttransplant maintenance therapy.","authors":"K Parker, E A Zagadailov, A S Bruno, A M Wiland","doi":"10.1155/2013/897434","DOIUrl":"https://doi.org/10.1155/2013/897434","url":null,"abstract":"Background. No studies have evaluated the impact of multiple generic immunosuppression medications on transplant coordinators (TCs) and patients. Methods. A cross-sectional, multicenter online survey of TCs managing transplant recipients' outpatient immunosuppression was undertaken to assess TCs' perceptions of the impact of multiple generic immunosuppression therapies on patients and workload. Results. Forty-six of 106 transplant centers contacted (43%) completed the survey, with usable information from 34 TCs (53% in centers performing >100 solid organ transplants annually, 82% registered nurses, and 68% with >5-year experience working with transplant patients). TCs indicated that \"change in strength,\" \"switching from branded to generics,\" \"heavy pill burden,\" and \"switching from one generic to another\" were the four most frequent reasons for patient confusion regarding immunosuppression. TCs reported increased patient confusion over the previous year for patients on generic immunosuppression therapy: 44% answered ≥3 patient calls/day regarding confusion over immunosuppression therapy. Most TCs indicated increased workload since the introduction of generic immunosuppression therapy. TCs perceived \"acute rejection rates,\" \"rate of graft loss,\" and \"poor patient adherence\" as the three most likely consequences of multiple generic immunosuppression therapy. Conclusion. TCs associated availability of multiple generic immunosuppression therapy with increased patient confusion and time spent addressing patient concerns.","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"897434"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/897434","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31200859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Should we consider patients with coexistent hepatitis B or C infection for orthotopic heart transplantation? 原位心脏移植是否应考虑合并乙肝或丙肝感染的患者?

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-11-07 DOI: 10.1155/2013/748578

Baskar Sekar, Pippa J Newton, Simon G Williams, Steven M Shaw

引用次数: 2

Preoperative cardiac variables of diastolic dysfunction and clinical outcomes in lung transplant recipients. 肺移植受者舒张功能障碍的术前心脏变量与临床结果。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-09-12 DOI: 10.1155/2013/391620

Ajay Yadlapati, Joseph P Lynch, Rajan Saggar, David Ross, John A Belperio, Stephen Weigt, Abbas Ardehali, Tristan Grogan, Eric H Yang, Jamil Aboulhosn

{"title":"Preoperative cardiac variables of diastolic dysfunction and clinical outcomes in lung transplant recipients.","authors":"Ajay Yadlapati, Joseph P Lynch, Rajan Saggar, David Ross, John A Belperio, Stephen Weigt, Abbas Ardehali, Tristan Grogan, Eric H Yang, Jamil Aboulhosn","doi":"10.1155/2013/391620","DOIUrl":"https://doi.org/10.1155/2013/391620","url":null,"abstract":"Background. Orthotopic lung transplantation is now widely performed in patients with advanced lung disease. Patients with moderate or severe ventricular systolic dysfunction are typically excluded from lung transplantation; however, there is a paucity of data regarding the prognostic significance of abnormal left ventricular diastolic function and elevated pretransplant pulmonary pressures. Methods. We reviewed the characteristics of 111 patients who underwent bilateral and unilateral lung transplants from 200 to 2009 in order to evaluate the prognostic significance of preoperative markers of diastolic function, including invasively measured pulmonary capillary wedge pressure (PCWP) and echocardiographic variables of diastolic dysfunction including mitral A > E and A' > E'. Results. Out of 111 patients, 62 were male (56%) and average age was 54.0 ± 10.5 years. Traditional echocardiographic Doppler variables of abnormal diastolic function, including A' > E' and A > E, did not predict adverse events (P = 0.49). Mildly elevated pretransplant PCWP (16-20 mmHg) and moderately/severely elevated PCWP (>20 mmHg) were not associated with adverse clinical events after transplant (P = 0.30). Additionally, all clinical endpoints did not show any statistical significance between the two groups. Conclusions. Pre-lung transplant invasive and echocardiographic findings of elevated pulmonary pressures and abnormal left ventricular diastolic function are not predictive of adverse posttransplant clinical events. ","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":" ","pages":"391620"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/391620","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40269469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Liver Transplantation without Perioperative Transfusions Single-Center Experience Showing Better Early Outcome and Shorter Hospital Stay. 肝移植无围手术期输血单中心经验显示更好的早期结果和更短的住院时间。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-12-12 DOI: 10.1155/2013/649209

Nicolás Goldaracena, Patricio Méndez, Emilio Quiñonez, Gustavo Devetach, Lucio Koo, Carlos Jeanes, Margarita Anders, Federico Orozco, Pablo D Comignani, Ricardo C Mastai, Lucas McCormack

{"title":"Liver Transplantation without Perioperative Transfusions Single-Center Experience Showing Better Early Outcome and Shorter Hospital Stay.","authors":"Nicolás Goldaracena, Patricio Méndez, Emilio Quiñonez, Gustavo Devetach, Lucio Koo, Carlos Jeanes, Margarita Anders, Federico Orozco, Pablo D Comignani, Ricardo C Mastai, Lucas McCormack","doi":"10.1155/2013/649209","DOIUrl":"https://doi.org/10.1155/2013/649209","url":null,"abstract":"Background. Significant amounts of red blood cells (RBCs) transfusions are associated with poor outcome after liver transplantation (LT). We report our series of LT without perioperative RBC (P-RBC) transfusions to evaluate its influence on early and long-term outcomes following LT. Methods. A consecutive series of LT between 2006 and 2011 was analyzed. P-RBC transfusion was defined as one or more RBC units administrated during or ≤48 hours after LT. We divided the cohort in \"No-Transfusion\" and \"Yes-Transfusion.\" Preoperative status, graft quality, and intra- and postoperative variables were compared to assess P-RBC transfusion risk factors and postoperative outcome. Results. LT was performed in 127 patients (\"No-Transfusion\" = 39 versus \"Yes-Transfusion\" = 88). While median MELD was significantly higher in Yes-Transfusion (11 versus 21; P = 0.0001) group, platelet count, prothrombin time, and hemoglobin were significantly lower. On multivariate analysis, the unique independent risk factor associated with P-RBC transfusions was preoperative hemoglobin (P < 0.001). Incidence of postoperative bacterial infections (10 versus 27%; P = 0.03), median ICU (2 versus 3 days; P = 0.03), and hospital stay (7.5 versus 9 days; P = 0.01) were negatively influenced by P-RBC transfusions. However, 30-day mortality (10 versus 15%) and one- (86 versus 70%) and 3-year (77 versus 66%) survival were equivalent in both groups. Conclusions. Recipient MELD score was not a predictive factor for P-RBC transfusion. Patients requiring P-RBC transfusions had worse postoperative outcome. Therefore, maximum efforts must be focused on improving hemoglobin levels during waiting list time to prevent using P-RBC in LT recipients. ","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"649209"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/649209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32054410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Systemic heparinisation in laparoscopic live donor nephrectomy. 腹腔镜活体供肾切除术中的全身肝素化治疗。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-12-16 DOI: 10.1155/2013/138926

Charlotte Crotty, Yasmin Tabbakh, Sarah A Hosgood, Michael L Nicholson

{"title":"Systemic heparinisation in laparoscopic live donor nephrectomy.","authors":"Charlotte Crotty, Yasmin Tabbakh, Sarah A Hosgood, Michael L Nicholson","doi":"10.1155/2013/138926","DOIUrl":"https://doi.org/10.1155/2013/138926","url":null,"abstract":"Introduction. Systemic heparinisation is advocated during laparoscopic live donor nephrectomy (LDN) as a preventative measure against renal vascular thrombosis during the warm ischaemic interval. This study compares the outcome with and without the administration of systemic heparinisation. Methods. A retrospective analysis was performed on 186 consecutive LDN patients between April 2008 and November 2012. Systemic heparin (2000-3000 IU) was administered intravenously to donors (hep n = 109). From January 2010, heparin was not used systemically in this group of LDN (no hep n = 77). Outcome measures included donor and recipient complications, initial graft function, and 12 month graft survival. Results. The demographics of both heparinised and non-heparinised donors were similar. The warm ischaemic time (WIT) was comparable in both groups (WIT; hep 5 ± 3 versus no hep 5 ± 3 minutes; P = 1.000). There was no difference in complication rates, no episodes of graft thrombosis, and no incidences of primary nonfunction in either group. Delayed graft function occurred in 4/109 and 1/77 (3.6% versus 1.2%; P = 0.405) and there was no significant difference in graft survival (P = 0.650). Conclusion. Omitting systemic heparinisation during laparoscopic donor nephrectomy is a feasible and safe approach that does not compromise donor or recipient outcome. ","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"138926"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/138926","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32054409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Occurrence of Fatal and Nonfatal Adverse Outcomes after Heart Transplantation in Patients with Pretransplant Noncytotoxic HLA Antibodies. 移植前非细胞毒性 HLA 抗体患者心脏移植后致命和非致命不良后果的发生率。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-07-29 DOI: 10.1155/2013/519680

Luciano Potena, Andrea Bontadini, Sandra Iannelli, Fiorenza Fruet, Ornella Leone, Francesco Barberini, Laura Borgese, Valentina Manfredini, Marco Masetti, Gaia Magnani, Francesco Fallani, Francesco Grigioni, Angelo Branzi

{"title":"Occurrence of Fatal and Nonfatal Adverse Outcomes after Heart Transplantation in Patients with Pretransplant Noncytotoxic HLA Antibodies.","authors":"Luciano Potena, Andrea Bontadini, Sandra Iannelli, Fiorenza Fruet, Ornella Leone, Francesco Barberini, Laura Borgese, Valentina Manfredini, Marco Masetti, Gaia Magnani, Francesco Fallani, Francesco Grigioni, Angelo Branzi","doi":"10.1155/2013/519680","DOIUrl":"10.1155/2013/519680","url":null,"abstract":"HLA antibodies (HLA ab) in transplant candidates have been associated with poor outcome. However, clinical relevance of noncytotoxic antibodies after heart transplant (HT) is controversial. By using a Luminex-based HLA screening, we retested pretransplant sera from HT recipients testing negative for cytotoxic HLA ab and for prospective crossmatch. Out of the 173 consecutive patients assayed (52 ± 13y; 16% females; 47% ischemic etiology), 32 (18%) showed pretransplant HLA ab, and 12 (7%) tested positive against both class I and class II HLA. Recipients with any HLA ab had poorer survival than those without (65 ± 9 versus 82 ± 3%; P = 0.02), accounting for a doubled independent mortality risk (P = 0.04). In addition, HLA-ab detection was associated with increased prevalence of early graft failure (35 versus 15%; P = 0.05) and late cellular rejection (29 versus 11%; P = 0.03). Of the subgroup of 37 patients suspected for antibody mediated rejection (AMR), the 9 with pretransplant HLA ab were more likely to display pathological AMR grade 2 (P = 0.04). By an inexpensive, luminex-based, HLA-screening assay, we were able to detect non-cytotoxic HLA ab predicting fatal and nonfatal adverse outcomes after heart transplant. Allocation strategies and desensitization protocols need to be developed and prospectively tested in these patients. ","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"519680"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31689918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current practice of heart donor evaluation in Germany: multivariable risk factor analysis confirms practicability of guidelines. 德国心脏供者评价的当前实践:多变量风险因素分析证实了指南的实用性。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-09-30 DOI: 10.1155/2013/701854

Sylke Ruth Zeissig, Carl-Ludwig Fischer-Froehlich, Frank Polster, Nils R Fruehauf, Guenter Kirste, Irene Schmidtmann

{"title":"Current practice of heart donor evaluation in Germany: multivariable risk factor analysis confirms practicability of guidelines.","authors":"Sylke Ruth Zeissig, Carl-Ludwig Fischer-Froehlich, Frank Polster, Nils R Fruehauf, Guenter Kirste, Irene Schmidtmann","doi":"10.1155/2013/701854","DOIUrl":"https://doi.org/10.1155/2013/701854","url":null,"abstract":"Background. Organ shortage has liberalised the acceptance criteria of grafts for heart transplantation, but which donor characteristics ultimately influence the decision to perform transplantation? For the first time this was evaluated using real-time donor data from the German organ procurement organization (DSO). Observed associations are discussed with regard to international recommendations and guidelines. Methods. 5291 German donors (2006-2010) were formally eligible for heart donation. In logistic regression models 160 donor parameters were evaluated to assess their influence on using grafts for transplantation (random split of cases: 2/3 study sample, 1/3 validation sample). Results. Successful procurement was determined by low donor age (OR 0.87 per year; 95% CI [0.85-0.89], P < 0.0001), large donor height (OR 1.04 per cm; 95% CI [1.02-1.06], P < 0.0001), exclusion of impaired left ventricular function or wall motion (OR 0.01; 95% CI [0.002-0.036], P < 0.0001), arrhythmia (OR 0.05; 95% CI [0.009-0.260], P = 0.0004), and of severe coronary artery disease (OR 0.003; 95% CI [<0.001-0.01], P < 0.0001). Donor characteristics differed between cases where the procedure was aborted without and with allocation initiated via Eurotransplant. ","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"701854"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/701854","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31839644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Impact of right-sided nephrectomy on long-term outcomes in retroperitoneoscopic live donor nephrectomy at single center. 右侧肾切除术对腹膜后单中心活体供肾切除术长期预后的影响。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-10-21 DOI: 10.1155/2013/546373

Kazuya Omoto, Taiji Nozaki, Masashi Inui, Tomokazu Shimizu, Toshihito Hirai, Yugo Sawada, Hideki Ishida, Kazunari Tanabe

{"title":"Impact of right-sided nephrectomy on long-term outcomes in retroperitoneoscopic live donor nephrectomy at single center.","authors":"Kazuya Omoto, Taiji Nozaki, Masashi Inui, Tomokazu Shimizu, Toshihito Hirai, Yugo Sawada, Hideki Ishida, Kazunari Tanabe","doi":"10.1155/2013/546373","DOIUrl":"https://doi.org/10.1155/2013/546373","url":null,"abstract":"Objective. To assess the long-term graft survival of right-sided retroperitoneoscopic live donor nephrectomy (RPLDN), we compared the outcomes of right- and left-sided RPLDN. Methods. Five hundred and thirty-three patients underwent live donor renal transplantation with allografts procured by RPLDN from July 2001 to August 2010 at our institute. Of these, 24 (4.5%) cases were selected for right-sided RPLDN (R-RPLDN) according to our criteria for donor kidney selection. Study variables included peri- and postoperative clinical data. Results. No significant differences were found in the recipients' postoperative graft function and incidence of slow graft function. Despite significant increased warm ischemic time (WIT: mean 5.9 min versus 4.7 min, P < 0.001) in R-RPLDN compared to that in L-RPLDN, there was no significant difference between the two groups regarding long-term patient and graft survival. The complication rate in R-RPLDN was not significantly different compared to that in L-RPLDN (17% versus 6.5%, P = 0.132). No renal vein thrombosis was experienced in either groups. Conclusions. Although our study was retrospective and there was only a small number of R-RPLDN patients, R-RPLDN could be an option for laparoscopic live donor nephrectomy because of similar results, with the sole exception of WIT, in L-RPLDN, and its excellent long-term graft outcomes. ","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"546373"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/546373","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31863344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

High-urgency renal transplantation: indications and long-term outcomes. 急症肾移植:指征和长期结果。

IF 2.5

Journal of Transplantation Pub Date : 2013-01-01 Epub Date: 2013-02-07 DOI: 10.1155/2013/314239

Lampros Kousoulas, Nikos Emmanouilidis, Wilfried Gwinner, Jürgen Klempnauer, Frank Lehner

{"title":"High-urgency renal transplantation: indications and long-term outcomes.","authors":"Lampros Kousoulas, Nikos Emmanouilidis, Wilfried Gwinner, Jürgen Klempnauer, Frank Lehner","doi":"10.1155/2013/314239","DOIUrl":"https://doi.org/10.1155/2013/314239","url":null,"abstract":"The concept of high-urgency (HU) renal transplantation was introduced in order to offer to patients, who are not able to undergo long-term dialysis treatment, a suitable renal graft in a short period of time, overcoming by this way the obstacle of the prolonged time spent on the waiting list. The goal of this study was to evaluate the patient and graft survivals after HU renal transplantation and compare them to the long-term outcomes of the non-high-urgency renal transplant recipients. The clinical course of 33 HU renal transplant recipients operated on at our center between 1995 and 2010 was retrospectively analyzed. The major indication for the HU renal transplantation was the imminent lack of access for either hemodialysis or peritoneal dialysis (67%). The patient survival of the study population was 67%, 56%, and 56%, whereas the graft survival was 47%, 35% and 35%, at 5, 10, and 15 years, respectively. In the comparison between our study population and the non-HU renal transplant recipients, our study population presented statistically significant (P < 0.05) lower patient survival rates. The HU renal transplant recipients also presented lower graft survival rates, but statistical significance (P < 0.05) was reached only in the 5-year graft survival rate.","PeriodicalId":45795,"journal":{"name":"Journal of Transplantation","volume":"2013 ","pages":"314239"},"PeriodicalIF":2.5,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/314239","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31296153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2