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Warfarin and Polypharmacy Challenges in Sudan: Drug Interactions in Patient Cohort. 苏丹的华法林和多种药物治疗挑战:病人群体中的药物相互作用。
IF 2.1
Integrated Pharmacy Research and Practice Pub Date : 2024-06-26 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S458827
Ahmed A A Omer, Abdal Mahmoud Elsiddig, Imad M Taj
{"title":"Warfarin and Polypharmacy Challenges in Sudan: Drug Interactions in Patient Cohort.","authors":"Ahmed A A Omer, Abdal Mahmoud Elsiddig, Imad M Taj","doi":"10.2147/IPRP.S458827","DOIUrl":"10.2147/IPRP.S458827","url":null,"abstract":"<p><strong>Purpose: </strong>Warfarin plays an important role in anticoagulation therapy despite the availability of the newest oral anticoagulants, and achieving optimal anticoagulation is challenging due to its narrow therapeutic range and variable dose. This study aimed to highlight polypharmacy and drug interactions in patients receiving warfarin therapy at Medani Heart Centre, Sudan.</p><p><strong>Methods: </strong>This retrospective hospital-based study was conducted from May 2017 to October 2018. Each concurrent medication prescribed for 104 patients was collected and checked for drug-drug interactions using Medscape Reference-Drug Interaction Checker. The data were analysed by using SPSS 20, and descriptive statistics were used.</p><p><strong>Results: </strong>The results revealed that 95.2% of patients had more than three medications in their profile, (3-5), (6-9) and more than 10 medications were prescribed for 40.4%, 44.2% and 10.6% of patients, respectively. A total of 93.3% of patients had drug-drug interactions, as follows: (1-5), (6-10), (11-15), (16-20) and more than 20 drug-drug interactions were found in 31.7%, 32.7%, 19.2%, 5.8% and 3.8% of patients, respectively. A total of 178 warfarin-drug interactions were identified in 88.5% of the patients. The INR ranged between 2 and 2.99 in 13.4% of patients, and INR values below 2 and above 5 were found in 44.2% and 21.2% of patients, respectively. Analgesics (n=54; 30.3%), cardiovascular drugs (n=51; 28.6%), and anticoagulants (n=46; 25.8%) were the most common drug classes that interact with warfarin. Significant and serious types of interactions with warfarin were found in 51% and 37.5% of patients, respectively.</p><p><strong>Conclusion: </strong>This study highlights the complexity of managing warfarin therapy amid prevalent polypharmacy. A substantial majority of patients experienced multiple drug interactions. The identification of significant and serious interactions emphasizes the need for vigilant management strategies, including improved communication among healthcare professionals and targeted education for both providers and patients, to enhance the safety and efficacy of warfarin therapy.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"81-89"},"PeriodicalIF":2.1,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11214771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Yemeni Physicians' Attitudes and Perceived Barriers Toward Ward-Based Clinical Pharmacist in Hospital Settings. 也门医生对医院病房临床药师的态度和认知障碍。
IF 2.1
Integrated Pharmacy Research and Practice Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S464258
Najmaddin A H Hatem, Mohammed A Kubas, Seena A Yousuf, Abdunaser Rassam, Mohamed Izham Mohamed Ibrahim
{"title":"Yemeni Physicians' Attitudes and Perceived Barriers Toward Ward-Based Clinical Pharmacist in Hospital Settings.","authors":"Najmaddin A H Hatem, Mohammed A Kubas, Seena A Yousuf, Abdunaser Rassam, Mohamed Izham Mohamed Ibrahim","doi":"10.2147/IPRP.S464258","DOIUrl":"10.2147/IPRP.S464258","url":null,"abstract":"<p><strong>Background: </strong>Clinical pharmacy services (CPSs) are still in their infancy in Yemen. Furthermore, pharmacists are not members of a multidisciplinary healthcare team, so their responsibilities are limited to drug dispensing and marketing. This study examines physicians' attitudes and perceived obstacles regarding the inclusion of clinical pharmacists in hospital medical wards.</p><p><strong>Methods: </strong>A descriptive observational study was carried out using a validated, self-administered bilingual questionnaire. The study's questionnaire was conducted among physicians in three leading hospitals. Those hospitals were at the forefront of establishing clinical pharmacy units and embracing clinical pharmacy services. Data were analyzed using descriptive statistics.</p><p><strong>Results: </strong>Sixty-five responses were included. Our data results indicated that physicians believed the most important contributions for clinical pharmacists to improve patient care were \"attending medical rounds\", followed by \"order review\". About 75% of physicians showed positive attitudes toward the clinical pharmacist role. However, more than 70% of physicians believed that clinical pharmacists should leave patient care to other healthcare professionals and focus on drug products. Not enough clinical pharmacist staff working in the health center was considered the top perceived barrier (83.1%), followed by \"clinical pharmacist responsibilities were not clearly defined\" and \"clinical pharmacist recommendations are not properly documented\".</p><p><strong>Conclusion: </strong>Strategies to expand clinical pharmacy services in Yemen should focus on several key areas. Protocols must be established to clearly outline the collaboration between clinical pharmacists and physicians. Additionally, fostering inter-professional relationships is crucial to overcoming resistance and increasing awareness and understanding of CPS adoption among healthcare team members.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"69-80"},"PeriodicalIF":2.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11192290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attitude and Practice of Pharmacy Students Toward Traditional Herbal Medicines, Sudan. 苏丹药剂学学生对传统草药的态度和实践。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2024-05-28 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S465056
Ebaa I Mahmoud, Mariam A Yousif, Ahmed H Arbab
{"title":"Attitude and Practice of Pharmacy Students Toward Traditional Herbal Medicines, Sudan.","authors":"Ebaa I Mahmoud, Mariam A Yousif, Ahmed H Arbab","doi":"10.2147/IPRP.S465056","DOIUrl":"10.2147/IPRP.S465056","url":null,"abstract":"<p><strong>Purpose: </strong>Traditional herbal medicines (THMs) are widely used in Sudan, but there is scarcity of research on pharmacy students' attitudes and utilization of THMs. This study aims to assess the attitudes and practices of pharmacy students toward THM.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted among randomly selected undergraduate pharmacy students at the University of Khartoum (Sudan). Data were collected using a validated self-administered questionnaire adapted from previous studies. A statistical package for the social sciences was used for data analysis.</p><p><strong>Results: </strong>Among the 264 respondents, the average age was 21.8 years, and 84.8% of them were females. Nearly 85% of respondents were residents of Khartoum. The overall respondent's attitudes towards THMs were positive, it ranged from high (19.7%), moderate (79.9%). About 87.8% of respondents are interested in learning more about THMs. In addition, 36.4%, and 50.4% of respondents strongly agreed or agreed that THMs should be officially licensed and controlled. A 17.8% and 63.3% of respondents, respectively, reported using traditional herbal remedies either always or occasionally. Supermarkets (35.2%) and friends/family (36.4%) were the main sources of THMs for the participants, and oral administration was the most used route (87.1%). More than 90% of respondents said they would suggest THMs to others, and the most common justifications for doing so were their accessibility (46.6%) and affordability (16.3%). The most widely used herbs were <i>Mentha spicata, Zingiber officinale, Acacia nilotica, Hibiscus sabdariffa, and Syzygium aromaticum</i>. Data revealed a significant association between attitude levels and respondents' gender (p=0.046), year of study (p=0.000), and residence (p=0.017).</p><p><strong>Conclusion: </strong>Most undergraduate pharmacy students had a positive attitude and utilized THMs. Development of effective educational initiatives, research, and regulations are recommended to ensure the appropriate utilization of traditional herbal remedies.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"61-68"},"PeriodicalIF":2.9,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Clinical Pharmacist Intervention in the Intensive Care Unit, Wad Medani, Sudan: A Cross-Sectional, Prospective Study. 临床药剂师干预对苏丹 Wad Medani 重症监护室的影响:一项横断面前瞻性研究。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2024-05-09 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S459170
Yousif B Hamadalneel, Hifa O Ahmed
{"title":"Impact of Clinical Pharmacist Intervention in the Intensive Care Unit, Wad Medani, Sudan: A Cross-Sectional, Prospective Study.","authors":"Yousif B Hamadalneel, Hifa O Ahmed","doi":"10.2147/IPRP.S459170","DOIUrl":"10.2147/IPRP.S459170","url":null,"abstract":"<p><strong>Purpose: </strong>Critical care pharmacists are uniquely qualified to provide a key role within the critical care multi-disciplinary team in managing the aspect of therapy, given their contributions to improved patient outcomes, medication safety, and reduced cost of the drug. Therefore, the purpose of this study was to assess the frequency, type, and impact of clinical pharmacist interventions in the Intensive Care Unit and their physicians' acceptance.</p><p><strong>Methods: </strong>This was a cross-sectional, prospective study. Data were gathered over six months (15th June 2023 to 15th December 2023) on a daily basis, with a minimum sample size of 384 interventions. All patients admitted to the ICU at Wad Medani Teaching Hospital, Gezira State, Sudan during the study period were included.</p><p><strong>Results: </strong>In general, a total of 510 interventions were made for 123 patients throughout the six months course of study. Among them, 493 (96.7%) clinical pharmacist interventions were agreed by physicians. Among categories of interventions, most of the recommendations were concerned about safety 34.11% (174/510), in which drug discontinuation due to long duration was the highest one 48.27% (48/174) followed by the renal dose adjustment 30.46% (53/174). Another clinical intervention involving indication accounted for 23.33% (119/510) in second place. Regarding the cost-saving interventions the study showed that, of the total number of interventions, 124 had a costrelated component, accounting for (24.31%) of the total interventions. Among all the interventions, the addition of drug, with a frequency of 103 (20.2%) was the most recurring intervention, followed by dosing at 100 (19.6%), and renal dose adjustment at 53 (10.4%).</p><p><strong>Conclusion: </strong>This study demonstrated how clinical pharmacists might enhance critical care patients' quality management while reducing the costs associated with medication and care. In addition, it contributes valuable insights into the integration of clinical pharmacists in ICU settings, especially in resource-limited environments.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"43-49"},"PeriodicalIF":2.9,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11090122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge and Attitude of Community Pharmacists Toward Cow Milk Protein Allergy Complications and Treatment in Children: A Cross-Sectional Study in Sudan. 社区药剂师对儿童牛奶蛋白过敏并发症和治疗的认识和态度:苏丹横断面研究
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S454850
Zahraa Elrasheed Ali, Abdelrahim Elameen, Fatima A Fadul, Rawan R Babikir, Ahmed H Arbab
{"title":"Knowledge and Attitude of Community Pharmacists Toward Cow Milk Protein Allergy Complications and Treatment in Children: A Cross-Sectional Study in Sudan.","authors":"Zahraa Elrasheed Ali, Abdelrahim Elameen, Fatima A Fadul, Rawan R Babikir, Ahmed H Arbab","doi":"10.2147/IPRP.S454850","DOIUrl":"10.2147/IPRP.S454850","url":null,"abstract":"<p><strong>Background: </strong>Cow's milk protein allergy is the most frequent type of food allergy in newborns and young children. It affects numerous body systems. A community pharmacist possessing adequate knowledge and appropriate practices is crucial for the management of the disease.</p><p><strong>Objectives: </strong>: This study aimed to assess the knowledge and attitude of community pharmacists toward the complications and treatment of cow milk protein allergy.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted among 332 randomly selected community pharmacists in the Capital of Sudan (Khartoum state). Data were collected using a validated and internally consistent (Cronbach Alpha = 0.712) self-administered questionnaire Descriptive statistics and Chi-square analysis were conducted using Statistical Package for the Social Sciences version 25.</p><p><strong>Results: </strong>The response rate was 95.8%, and about 47.8% of the population had 1-5 years of experience as community pharmacists, and 37.4% of them had a post-graduate degree. Only 30.8% of respondents had good knowledge, while 40.6% had poor knowledge, and 28.6% had scored as having fair knowledge of complications of Cow's milk protein allergy. Regarding knowledge toward treatment, 65.1% of respondents had a poor knowledge, 24.5% had fair knowledge, and only 10.4% had good knowledge. Overall, 39.62% of participants had a positive attitude, and 60.38% had a negative attitude toward this disease. Data analysis showed no significant association between the sociodemographic characteristics of respondents and their knowledge and attitude.</p><p><strong>Conclusion: </strong>Community pharmacists in Khartoum State had inadequate knowledge and attitude about the complications and treatment of cow milk protein allergy. As a result, we recommend the implementation of strategies to raise pharmacists' knowledge and attitude.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"51-60"},"PeriodicalIF":2.9,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11088822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug Use Evaluation of Tenofovir/Lamivudine/Dolutegravir (TLD) Fixed-Dose Combination for Initiation and Transition Among HIV-Infected Individuals Attending Lumame Primary Hospital, North West Ethiopia. 对埃塞俄比亚西北部 Lumame 初级医院就诊的 HIV 感染者使用替诺福韦/拉米夫定/多度拉韦 (TLD) 固定剂量复方制剂进行初始和过渡用药评估。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2024-04-18 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S455351
Bantayehu Addis Tegegne, Agumas Alemu Alehegn, Mengistie Kassahun
{"title":"Drug Use Evaluation of Tenofovir/Lamivudine/Dolutegravir (TLD) Fixed-Dose Combination for Initiation and Transition Among HIV-Infected Individuals Attending Lumame Primary Hospital, North West Ethiopia.","authors":"Bantayehu Addis Tegegne, Agumas Alemu Alehegn, Mengistie Kassahun","doi":"10.2147/IPRP.S455351","DOIUrl":"https://doi.org/10.2147/IPRP.S455351","url":null,"abstract":"<p><strong>Background: </strong>A key strategy for quality improvement is drug use evaluation, which looks at the safe, appropriate use of medication principles. Tenofovir/Lamivudine/Dolutegravir (TLD-FDC) usage has not yet been sufficiently examined in published literature. The purpose of this study was to assess how TLD were used by HIV-positive patients Using WHO drug use evaluation standards in Lumame Primary Hospital, North West Ethiopia.</p><p><strong>Methods: </strong>Using WHO drug use evaluation standards, a retrospective study design was used to evaluate the appropriateness of TLD use. Systematic random sampling was utilized to gather patient medical records containing TLD. Accordingly, 100 records that met the inclusion criteria were selected and reviewed between April 1 and 15, 2021. Five criteria, namely, indication, dose, contraindication, drug interaction, and TLD safety monitoring were used to evaluate the appropriateness of TLD utilization.</p><p><strong>Results: </strong>80% of patients were transited to TLD from other regimens. The median time on TLD was found to be 13 months with 9 months to 18 months IQR. The latest CD4 count as well as CD4 count at the initiation or transition of TLD was not done for 75% and 89% of the patients, respectively. 3/4 (75%) of the patients were found to have a scheduled medication refill history. TLD dosing, indications, and contraindications were found to be 100% appropriate. No, TLD safety monitoring tests were done for 21% of the patients in this study. However, viral load, liver/kidney function, and serum creatinine tests were done for 77% (95% CI: 74%-79%), 5% (95% CI: 2%-8%), and 14% (95% CI: 11%-17%) of the patients, respectively. More over, In 93% (95% CI: 91%-95%) of the patients, the TLD interaction was appropriate; in 7%, it was not. All recording, documenting, and reporting technologies were available and used efficiently, except for the Electronic Dispensing Tool.</p><p><strong>Conclusion: </strong>Generally, good adherence to national and WHO guidelines was obtained regarding dose, indication, and contraindications. However, improvement in safety monitoring tests and CPT utilization is recommended. Drug interactions satisfied the majority of the criteria's threshold, while certain standards were not followed.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"31-42"},"PeriodicalIF":2.9,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Rational Medicines Use Based on World Health Organization Core Indicators: A Cross-Sectional Study in Five Health Districts in Mauritania. 基于世界卫生组织核心指标的合理用药评估:毛里塔尼亚五个卫生区的横断面研究。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2024-03-28 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S447664
Mohamed Ali Ag Ahmed, Raffaella Ravinetto, Khadijetou Diop, Verónica Trasancos Buitrago, Catherine Dujardin
{"title":"Evaluation of Rational Medicines Use Based on World Health Organization Core Indicators: A Cross-Sectional Study in Five Health Districts in Mauritania.","authors":"Mohamed Ali Ag Ahmed, Raffaella Ravinetto, Khadijetou Diop, Verónica Trasancos Buitrago, Catherine Dujardin","doi":"10.2147/IPRP.S447664","DOIUrl":"https://doi.org/10.2147/IPRP.S447664","url":null,"abstract":"<p><strong>Introduction: </strong>The rational use of medicines is essential for preventing adverse medicine reactions, achieving therapeutic outcomes, and optimizing treatment costs. While the irrational use of medicines is frequently reported in sub-Saharan Africa, to the best of our knowledge no formal studies have taken place in Mauritania thus far. The main objective of this study was therefore to analyze the rational use of medicines in public and private not-for-profit health facilities, in five health districts in Mauritania.</p><p><strong>Methods: </strong>We conducted a cross-sectional study to assess the rational use of medicines. We used the standard indicators derived from the methodologies of the World Health Organization (WHO) and International Network for Rational Use of Drugs (INRUD). Data were prospectively collected from 1050 prescriptions/patients, in thirty-one public and private not-for-profit health posts/centers in 5 health districts. The data were analyzed using the Statistical Package for the Social Sciences. P value less than 0.05 at 95% confidence interval considered for significance of relationships for associations in statistical test.</p><p><strong>Results: </strong>The average number of medicines per prescription was 2.21; 83.1% (1931/2325) of medicines were prescribed by generic name, but only 54% (1253/2325) were on the National Essential Medicine List (NEML). Antibiotics were prescribed in 62.4% (655/1050) of the consultations, and injectable medicines were prescribed in 15.6% (164/1050) of the consultations. The average consultation time was 16.32 minutes, and the average dispensing time was 97 seconds. Dispensed medicines were correctly labeled, and 83% (871/1050) of patients met the correct administration schedule. The NEML, and the \"restricted NEML\" for 76 commonly-used medicines, were available in all surveyed health facilities, but the National Therapeutic Guidelines were available in only 60.26% of them.</p><p><strong>Conclusion: </strong>Our findings indicate a possible excess of antibiotics prescriptions, and a likely lack of knowledge of the National Therapeutic Guidelines. There is a need to investigate in more detail the prescription patterns versus disease-specific therapeutic guidelines, and to qualitatively investigate the factors that contribute to the observed irrational prescribing. Moreover, training local staff in the rational use of medicines seems important.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"17-29"},"PeriodicalIF":2.9,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10984847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosimilars Would Reduce Health Care Costs But Are Yet Poorly Known - Patient Survey Study Among Biological Medicine Users. 生物仿制药可降低医疗成本,但人们对其知之甚少--生物药用户患者调查研究。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2024-02-03 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S440888
Mari Pölkki, Tuire Prami
{"title":"Biosimilars Would Reduce Health Care Costs But Are Yet Poorly Known - Patient Survey Study Among Biological Medicine Users.","authors":"Mari Pölkki, Tuire Prami","doi":"10.2147/IPRP.S440888","DOIUrl":"10.2147/IPRP.S440888","url":null,"abstract":"<p><strong>Background: </strong>From the beginning of the year 2024, gradually implemented amendment to the Medicines Act will enable interchange of biological medicines in pharmacies in Finland. The legislative change aims to reduce health care costs.</p><p><strong>Methods: </strong>Opinions of the biological medicine users regarding substitution in pharmacies and knowledge about biological medicines were determined by a patient survey in community pharmacies and via patient organizations in Finland.</p><p><strong>Results: </strong>In total, 199 users of biological medicines responded to the survey. The respondents did not always know which product they were using, an originator or a biosimilar. This was more prominent among patients with biosimilars determined according to brand names. The more recently the biological medicine had been prescribed, the more likely a biosimilar was in use. Only about 40% of the respondents would enable pharmacies to substitute their biological medicine to a lower cost product. The most common obstacle to the idea of interchange in pharmacies was that the respondents wanted to keep the product the doctor had prescribed for them. In general, biosimilar users were more accepting towards possible interchange than originator users.</p><p><strong>Conclusion: </strong>Although the most recent treatments appear to be initiated with biosimilars, interchange in pharmacies could enable an efficient way to lower health care costs. However, guidance and awareness regarding biosimilars and biological medicines in general would improve patients' willingness towards the change, but also help pharmacists and prescribing doctors in their meaningful role.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"9-16"},"PeriodicalIF":2.9,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10849140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Entrepreneurship in Pharmacy: Attitudes and Perceptions Among Saudi Pharmacists and Students. 探索药剂学中的创业精神:沙特药剂师和学生的态度与观念。
IF 2.1
Integrated Pharmacy Research and Practice Pub Date : 2024-01-18 eCollection Date: 2024-01-01 DOI: 10.2147/IPRP.S441142
Mohammed Alnuhait, Nada Falah Alqurashi, Ghodwah Zubair Abdullatif, Manar Sami Maash, Refal Fagieha, Haneen Alshareef, Foud O Bahamdain, Waad Alghamdi, Abdullah A Alhifany
{"title":"Exploring Entrepreneurship in Pharmacy: Attitudes and Perceptions Among Saudi Pharmacists and Students.","authors":"Mohammed Alnuhait, Nada Falah Alqurashi, Ghodwah Zubair Abdullatif, Manar Sami Maash, Refal Fagieha, Haneen Alshareef, Foud O Bahamdain, Waad Alghamdi, Abdullah A Alhifany","doi":"10.2147/IPRP.S441142","DOIUrl":"10.2147/IPRP.S441142","url":null,"abstract":"<p><strong>Introduction: </strong>Entrepreneurship has recently become a focus in community development, innovation, and economic growth, including within pharmaceutical organizations. However, it remains a relatively new aspect of pharmacy education. For the effective incorporation of entrepreneurship in this field, a robust educational foundation is critical, one that emphasizes risk-taking, strategic planning, competitive spirit, and a sense of social responsibility. This study aims to evaluate Saudi pharmacists' attitudes towards entrepreneurship in their practice.</p><p><strong>Methods: </strong>A cross-sectional survey design to assess the attitudes of pharmacists and pharmacy students in Saudi Arabia towards entrepreneurship. The study sample consisted of 302 individuals, selected through convenience sampling, all of whom were either licensed pharmacists or pharmacy students in Saudi Arabia. The survey was conducted electronically and disseminated online throughout the duration of January 2023, spanning a one-month period. The research sought to provide a deeper understanding of how entrepreneurship is perceived within the pharmacy field.</p><p><strong>Results: </strong>The study involved 302 pharmacists in Saudi Arabia, with the majority being pharmacy students and Doctor of Pharmacy holders. Over 60% of the participants worked for the government sector. Results showed a strong interest in entrepreneurship, with nearly 80% expressing interest and believing in the entrepreneurial potential of pharmacists. However, there was a knowledge gap, as only 52% were familiar with entrepreneurship concepts, and most had not taken entrepreneurship courses. More than half of the participants reported insufficient institutional support for entrepreneurship. Remarkably, only 1% had started a pharmaceutical business.</p><p><strong>Conclusion: </strong>In conclusion, this study emphasizes the interest in entrepreneurship among pharmacists, highlighting the need for raising familiarity and formal education in the field. Factors such as working in the government sector were associated with higher willingness to become entrepreneurs, while the lack of awareness and institutional support hindered the entrepreneurial mindset.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"13 ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10802168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Promoting Internship Excellence: Key Strategies Employed by Pharmacy Schools for Successful Development. 促进卓越实习:药学院成功发展的关键策略》。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2023-12-05 eCollection Date: 2023-01-01 DOI: 10.2147/IPRP.S444727
Najmaddin A H Hatem
{"title":"Promoting Internship Excellence: Key Strategies Employed by Pharmacy Schools for Successful Development.","authors":"Najmaddin A H Hatem","doi":"10.2147/IPRP.S444727","DOIUrl":"https://doi.org/10.2147/IPRP.S444727","url":null,"abstract":"<p><p>Various early pharmacy practice experiences, such as introductory, advanced, and postgraduate internship programs, are part of the journey of future pharmacists during their educational experience in pharmacy schools. Pharmacy schools have the potential to enhance the quality of their internship programs by establishing strategies to provide comprehensive instruction and practical experience for students. Hence, this commentary shade light on the critical tactics employed by pharmacy schools to guarantee the growth and success of pharmacy students during their different internship programs.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"12 ","pages":"239-245"},"PeriodicalIF":2.9,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138811840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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