Bulletin of Tokyo Dental College最新文献

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Posterior Open Bite Due to Failure of Maxillary Molar Eruption. 上颌磨牙出牙失败后开咬。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2016-01-01 DOI: 10.2209/tdcpublication.2016-0800
Toshihiko Yasumura, K. Sueishi
{"title":"Posterior Open Bite Due to Failure of Maxillary Molar Eruption.","authors":"Toshihiko Yasumura, K. Sueishi","doi":"10.2209/tdcpublication.2016-0800","DOIUrl":"https://doi.org/10.2209/tdcpublication.2016-0800","url":null,"abstract":"Posterior open bite can cause problems with occlusion. It arises from systemic or local factors such as physical or functional interference, ankylosis, and failure of eruption. Primary failure of eruption (PFE) is a rare condition that is difficult to differentiate from ankylosis and requires complex treatment strategies. Here we report a 12-year-old girl who was referred to our hospital by her dentist for re-evaluation of eruption failure of the left maxillary secondary premolar and first and second molars with congenitally missing maxillary lateral teeth. The maxillary first molar was extracted for a therapeutic diagnosis. The left maxillary secondary premolar and second molar reacted well to subsequent orthodontic treatment. Auto-transplantation of the mandibular premolar to the maxil-lary arch was carried out to achieve optimal overjet, overbite, and occlusion. The active treatment period spanned 4 years and 1 month. Assessment of the patient's medical and dental history, prior trauma, and clinical conditions resulted in a therapeutic diagnosis of PFE. Satisfactory orthodontic treatment results were achieved.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"57 4 1","pages":"281-290"},"PeriodicalIF":0.5,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.2016-0800","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68185387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Participation of Patient Community Members in Communication Classes for Dental Students at Tokyo Dental College. 病人社群成员在东京牙科学院牙科学生交流课上的参与。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2016-01-01 DOI: 10.2209/tdcpublication.2015-0037
N. Takahashi, Hitoshi Yamamoto, Satoshi Murakami, S. Hirata, N. Sugihara, Riuji Mochizuki, Toshiyuki Takahashi, Yuko Sato, E. Kawada
{"title":"Participation of Patient Community Members in Communication Classes for Dental Students at Tokyo Dental College.","authors":"N. Takahashi, Hitoshi Yamamoto, Satoshi Murakami, S. Hirata, N. Sugihara, Riuji Mochizuki, Toshiyuki Takahashi, Yuko Sato, E. Kawada","doi":"10.2209/tdcpublication.2015-0037","DOIUrl":"https://doi.org/10.2209/tdcpublication.2015-0037","url":null,"abstract":"In 2009, the Ministry of Education, Culture, Sports, Science and Technology launched its \"Program for Promoting University Education and Student Support, Theme A: Program for Promoting University Education Reform\". The ministry's stated aims were to 1) enhance student training centered on the needs of the individual patient; 2) improve their ability to make comprehensive diagnosis and treatment plans; and 3) instill high ethical standards and good communication skills. One of the main pillars of this project was to establish an educational organization aimed at encouraging public participation, the \"Patient Community\". The aim was to have members of this community roleplay patients in the Communication Studies component of the 1st-4th years of dental school. It was hoped that they would be able to respond to the students in a more realistic manner than simulated patients. Here, the number of Patient Community members and number who attended Communication Studies classes in 2010, 2011, 2012, and 2014 were investigated. The results showed that the number registered in the Patient Community increased annually, as did the number participating in Communication Studies classes, which rose in accordance with the number of classes held. No difference was observed in the number of attendees per Communication Studies class by grade (years 1-4). The number of members never attending Community Studies classes increased annually, although some members repeatedly attended. These findings suggest that the members who regularly participate tend to remain the same.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"21 1","pages":"189-93"},"PeriodicalIF":0.5,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68185587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regional Anatomical Observation of Morphology of Greater Palatine Canal and Surrounding Structures. 大腭管及其周围结构的区域解剖观察。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2016-01-01 DOI: 10.2209/tdcpublication.2016-1100
Masashi Suzuki, Yuya Omine, Yoshiaki Shimoo, Masahito Yamamoto, A. Kaketa, M. Kasahara, Masamitu Serikawa, S. Rhee, Tadatoshi Matsubayashi, S. Matsunaga, S. Abe
{"title":"Regional Anatomical Observation of Morphology of Greater Palatine Canal and Surrounding Structures.","authors":"Masashi Suzuki, Yuya Omine, Yoshiaki Shimoo, Masahito Yamamoto, A. Kaketa, M. Kasahara, Masamitu Serikawa, S. Rhee, Tadatoshi Matsubayashi, S. Matsunaga, S. Abe","doi":"10.2209/tdcpublication.2016-1100","DOIUrl":"https://doi.org/10.2209/tdcpublication.2016-1100","url":null,"abstract":"In maxillary molar region implant therapy, support is sometimes obtained from trabecular bone comprising the maxillary tuberosity, pterygoid process of the sphenoid bone, and pyramidal process of the palatine bone. Great care is necessary in such cases due to the presence of the greater palatine canal, which forms a passageway for the greater palatine artery, vein, and nerve. However, clinical anatomical reports envisioning embedding of pterygomaxillary implants in this trabecular bone region have been limited in number. In this study, the 3-D morphology of the greater palatine canal region, including the maxillary tuberosity region and points requiring particular care in pterygomaxillary implantation, were therefore investigated. Micro-CT was used to image 20 dentulous jaws (40 sides) harvested from the dry skulls of Japanese individuals with a mean age of 28.2 years at time of death. The skulls were obtained from the Jikei University School of Medicine cadaver repository. Three-dimensional reconstruction of the trabecular bone region, including the greater palatine canal, was performed using software for 3-D measurement of trabecular bone structure. Trabecular bone region morphometry was performed with the hamular notch-incisive papilla (HIP) plane as the reference plane. The results showed a truncated-cone structure with the greater palatine foramen as the base extending to the pterygopalatine fossa. This indicates the need for care with respect to proximity of the dental implant body to the greater palatine canal and the risk of perforation if it is embedded in the maxillary tuberosity region at an inclination of 60° toward the lingual side. Moreover, caution must be exercised to avoid possible damage to the medial wall of the maxillary sinus if the inclination of the embedded dental implant body is almost perpendicular to the HIP plane.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"15 1","pages":"223-231"},"PeriodicalIF":0.5,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.2016-1100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68185701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Tooth Loss in Problem-oriented, Irregular, and Regular Attenders at Dental Offices. 牙齿脱落的问题导向,不定期和定期到牙科诊所就诊。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2016-01-01 DOI: 10.2209/tdcpublication.57.11
K. Yoshino, Koji Ito, M. Kuroda, N. Sugihara
{"title":"Tooth Loss in Problem-oriented, Irregular, and Regular Attenders at Dental Offices.","authors":"K. Yoshino, Koji Ito, M. Kuroda, N. Sugihara","doi":"10.2209/tdcpublication.57.11","DOIUrl":"https://doi.org/10.2209/tdcpublication.57.11","url":null,"abstract":"The aim of this retrospective study was to compare number of teeth lost among regular attenders (RAs), irregular attenders (IRAs), and problem-oriented attenders (POAs) at dental offices over a 10-yr observation period. Information on tooth loss was obtained from general practitioners. Patients were divided into 3 groups based on appointment adherence. A total of 1,886 teeth were lost in 1,400 patients. The mean number of teeth lost in men was 2.2±2.6 per patient over 10 yr in POAs, 1.2±1.7 in IRAs, and 1.5±1.5 in RAs. This number was significantly lower in IRAs (p = 0.011) or RAs (p=0.012) than in POAs. When the dependent variable was defined as \"a patient with at least 2 or more extracted teeth\", the independent variables showed the following correlations with tooth loss: IRAs (OR: 0.54; 95%CI: 0.35-0.84), RAs (OR: 0.65; 95%CI: 0.47-0.89), man (OR: 1.43; 95%CI: 1.11-1.83), hypertension (OR: 1.38; 95%CI: 1.04-1.85), 20-25 present teeth (OR: 2.41; 95%CI: 1.81-3.22), and 1-19 present teeth (OR: 3.75; 95%CI: 2.73-5.16). The risk of tooth loss showed a 0.65-fold increase in RAs undergoing maintenance compared with POAs. Motivating patients to visit the dentist more regularly and undergo maintenance is important. The present results may be of use to dental professionals in providing patients with detailed information on potential tooth loss and associated risk factors with the aim of achieving such a change in behavior.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"57 1 1","pages":"11-9"},"PeriodicalIF":0.5,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.57.11","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68186933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Effect of Cuff Pressure Elevation on Internal Diameter of Tracheal Tube in Simulated Trachea. 模拟气管中袖套压力升高对气管内径的影响。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2016-01-01 DOI: 10.2209/tdcpublication.57.7
Yukiko Matsuki, N. Matsuura, T. Ichinohe
{"title":"Effect of Cuff Pressure Elevation on Internal Diameter of Tracheal Tube in Simulated Trachea.","authors":"Yukiko Matsuki, N. Matsuura, T. Ichinohe","doi":"10.2209/tdcpublication.57.7","DOIUrl":"https://doi.org/10.2209/tdcpublication.57.7","url":null,"abstract":"Application of nitrous oxide during anesthesia causes an increase in tracheal tube cuff pressure over time. The purpose of this study was to investigate the effect of an increase in cuff pressure on 3 types of tube (the Portex, Mallinckrodt, and Parker) commonly used for nasotracheal intubation. A cylindrical vessel was used to simulate a trachea. Cuff pressure was set at 0 cmH2O (R0) or 20 cmH2O (R20) at room temperature, or at 20 cmH2O (H20), 40 cmH2O (H40), 60 cmH2O (H60), or 80 cmH2O (H80) in 38°C hot water and pressure applied for 30 min. The value obtained at R0 was used as a reference (100%) and the rate of change under each condition determined. No change was observed at R20 in any of the 3 groups. In 38°C hot water, internal diameter in the Portex group decreased by 5.4% at H20 and 7.3% at H40, while that in the Mallinckrodt group decreased by 6% at H40. No significant change was observed in internal diameter in the Parker group, even when cuff pressure was increased. The internal diameter in the Portex group was the smallest at all cuff pressures in hot water. When the nasotracheal intubation tubes selected were placed in a simulated trachea and cuff pressure increased, internal diameter in the Portex and Mallinckrodt groups decreased.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"57 1 1","pages":"7-10"},"PeriodicalIF":0.5,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.57.7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68187050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Radiopacity Measurement of Restorative Resins Using Film and Three Digital Systems for Comparison with ISO 4049: International Standard. 用胶片和三数字系统测量恢复树脂的不透明度与ISO 4049:国际标准的比较。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2015-01-01 DOI: 10.2209/tdcpublication.56.207
R. Kapila, Y. Matsuda, K. Araki, T. Okano, K. Nishikawa, T. Sano
{"title":"Radiopacity Measurement of Restorative Resins Using Film and Three Digital Systems for Comparison with ISO 4049: International Standard.","authors":"R. Kapila, Y. Matsuda, K. Araki, T. Okano, K. Nishikawa, T. Sano","doi":"10.2209/tdcpublication.56.207","DOIUrl":"https://doi.org/10.2209/tdcpublication.56.207","url":null,"abstract":"This study compared Ultra Speed Occlusal Film (USOF) and 3 digital systems in determining the radiopacity of 5 different restorative resins in terms of equivalents of aluminum thickness. Whether those digital systems could be used to determine whether radiopacity was in line with International Organization for Standardization (ISO) recommendations was also investigated. Disks of each of 5 restorative resins and an aluminum step wedge were exposed at 65 kVp and 10 mA on USOF and imaged with each digital system. Optical density on the film was measured with a transmission densitometer and the gray values on the digital images using Image J software. Graphs showing gray value/optical density to step wedge thickness were constructed. The aluminum equivalent was then calculated for all the resins using a regression equation. All the resins were more radiopaque than 1 mm of aluminum, and therefore met the ISO 4049 recommendations for restorative resins. Some resins showed statistically higher aluminum equivalents with digital imaging. The use of traditional X-ray films is declining, and digital systems offer many advantages, including an easy, fast, and reliable means of determining the radiopacity of dental materials.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"56 4 1","pages":"207-14"},"PeriodicalIF":0.5,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.56.207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68187186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Metabolic Syndrome, Lifestyle, and Dental Caries in Japanese School Children. 日本学龄儿童的代谢综合征、生活方式和龋齿。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2015-01-01 DOI: 10.2209/tdcpublication.56.233
H. Osawa, N. Sugihara, T. Ukiya, Y. Ishizuka, D. Birkhed, Masaru Hasegawa, T. Matsukubo
{"title":"Metabolic Syndrome, Lifestyle, and Dental Caries in Japanese School Children.","authors":"H. Osawa, N. Sugihara, T. Ukiya, Y. Ishizuka, D. Birkhed, Masaru Hasegawa, T. Matsukubo","doi":"10.2209/tdcpublication.56.233","DOIUrl":"https://doi.org/10.2209/tdcpublication.56.233","url":null,"abstract":"The number of children with Metabolic Syndrome (MetS) has recently been increasing in Japan. Few studies have investigated the relationship between MetS and oral health. The aim of this study was to investigate the association between MetS, lifestyle, and oral health status in school children. Our goal is to utilize these results in health education aimed at preventing the onset of MetS in school children and adults. A total of 689 Japanese children (365 boys and 324 girls) aged between 10 and 13 years were examined and waist circumference (WC), ratio of WC to height, blood pressure, fasting blood sugar (FBS), high density lipoprotein-cholesterol, and triglyceride values determined together with oral health status, including dental caries experience (DMFT). The results revealed that 6.5% of the children fell under the health board recognized \"MetS or high risk of MetS\" (MetS/HR) classification. A total of 140 (20%) children had a high Streptococcus mutans count. The mean WC, FBS, and DMFT values were significantly greater in children with a high salivary S. mutans count (p<0.05). Multiple logistic regression analysis revealed a statistically significance association between MetS/HR, non-breakfast eaters (odds ratio (OR): 2.70), no regular exercise (OR: 2.60), and a high salivary S. mutans count (≥10(5) CFU/ml; OR: 2.18; p<0.05). The present results indicate that lifestyle and salivary S. mutans count could be useful in screening children for MetS/HR. These variables may be useful in targeting interventions aimed at preventing MetS in school children.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"56 4 1","pages":"233-41"},"PeriodicalIF":0.5,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.56.233","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68187292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Case of Severe Maxillary Protrusion Accompanied by Crowding and Scissor Bite. 上颌严重突出伴拥挤、剪咬1例。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2015-01-01 DOI: 10.2209/tdcpublication.56.243
Hidenori Katada, K. Sueishi
{"title":"Case of Severe Maxillary Protrusion Accompanied by Crowding and Scissor Bite.","authors":"Hidenori Katada, K. Sueishi","doi":"10.2209/tdcpublication.56.243","DOIUrl":"https://doi.org/10.2209/tdcpublication.56.243","url":null,"abstract":"This case involved a 30-year-old woman who visited our hospital with the main complaint of protrusion of the maxillary incisors and upper and lower lips. She had difficulty closing her lips, and a chin button was observed when the lips were closed. The skeletal pattern showed maxillary protrusion and mandibular retrusion, and the mandible showed severe high angle. Labial inclination of both the maxillary and mandibular incisors was found, as well as crowding. In addition, the maxillary left second molar showed buccal displacement, and scissor bite was evident in the left second molar region. The bilateral molar relationship was cusp-to-cusp class II malocclusion. Angle class II maxillary protrusion accompanied by crowding and left second molar scissor bite was diagnosed. Surgical orthodontic treatment was judged as the best approach to treat the jaw deformities. However, in line with the wishes of the patient, treatment was undertaken using implant anchors instead. Straight-wire brackets with a 0.022-inch slot were fitted. A lingual arch was placed in the mandible and plate-type implant anchors in the first molar region of the maxilla. Almost no change was observed in skeletal pattern as no surgery was performed. The maxillary incisors moved back 10 mm, however, and the mandibular incisors showed an improvement of 4 mm from L1 to APo. The upper and lower lips consequently moved back 7 mm with respect to the E-line. Active treatment required 3 years and 6 months. Esthetic and functional improvements were achieved.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"56 4 1","pages":"243-51"},"PeriodicalIF":0.5,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.56.243","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68187339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Basic Finite Element Analysis of Para-periodontal Ligament in All-ceramic Zirconia Fixed Partial Denture. 全陶瓷氧化锆固定局部义齿牙周旁韧带的基本有限元分析。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2015-01-01 DOI: 10.2209/tdcpublication.56.215
Syuntaro Nomoto, S. Matsunaga, Toru Sato, Mamoru Yotsuya, S. Abe
{"title":"Basic Finite Element Analysis of Para-periodontal Ligament in All-ceramic Zirconia Fixed Partial Denture.","authors":"Syuntaro Nomoto, S. Matsunaga, Toru Sato, Mamoru Yotsuya, S. Abe","doi":"10.2209/tdcpublication.56.215","DOIUrl":"https://doi.org/10.2209/tdcpublication.56.215","url":null,"abstract":"The purpose of the present study was to investigate the validity of incorporating a para-periodontal ligament in the test mold used in a basic fracture test of a zirconia all-ceramic fixed partial denture (FPD). A simplified three-dimensional finite element analysis model was designed based on the three-unit FPD fracture test. Two types of model, one with and one without a para-periodontal ligament between the abutment and base mold, were fabricated. Microfocus CT of the missing first molar area in a dry human mandible was performed. A three-dimensional model was then fabricated based on the data obtained. A load of 600 N was applied to the center of the pontic and stress distribution observed. The model with the para-periodontal ligament showed stress dispersion to the dental root with rotation of the abutment mold. Stress distribution in the finite element analysis model with a para-periodontal ligament showed greater similarity with that in the mandibular model than with that in the other two models without a para-periodontal ligament.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"56 4 1","pages":"215-22"},"PeriodicalIF":0.5,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.56.215","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68187263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Transient Receptor Potential Cation Channel Subfamily Vanilloid Member 3 is not Involved in Plasma Membrane Stretch-induced Intracellular Calcium Signaling in Merkel Cells. 瞬时受体电位阳离子通道亚家族香草酸蛋白3成员不参与默克尔细胞质膜拉伸诱导的细胞内钙信号传导。
IF 0.5
Bulletin of Tokyo Dental College Pub Date : 2015-01-01 DOI: 10.2209/tdcpublication.56.259
A. Higashikawa, Y. Kojima, Masaki Sato, M. Kimura, Kazuhiro Ogura, H. Mochizuki, T. Sase, Akinori Shinya, Kunio Kobune, Tadashi Furuya, Toru Sato, Y. Shibukawa, M. Tazaki
{"title":"Transient Receptor Potential Cation Channel Subfamily Vanilloid Member 3 is not Involved in Plasma Membrane Stretch-induced Intracellular Calcium Signaling in Merkel Cells.","authors":"A. Higashikawa, Y. Kojima, Masaki Sato, M. Kimura, Kazuhiro Ogura, H. Mochizuki, T. Sase, Akinori Shinya, Kunio Kobune, Tadashi Furuya, Toru Sato, Y. Shibukawa, M. Tazaki","doi":"10.2209/tdcpublication.56.259","DOIUrl":"https://doi.org/10.2209/tdcpublication.56.259","url":null,"abstract":"Merkel cells (MCs), which form part of the MC-neurite complex, making contact with sensory afferents to drive mechanosensory transduction mechanisms, express transient receptor potential (TRP) cation channel subfamily vanilloid (V) members 1, 2, and 4, as well as ankyrin subfamily member 1. While these proteins are involved in sensing plasma membrane stretch, less is known about the functional properties of TRPV subfamily member 3 (TRPV3) during membrane stretch in MCs. The aim of this study was to determine whether TRPV3 channels were involved in mechanosensory activity by measuring intracellular free Ca(2+) concentrations ([Ca(2+)]i) in MCs isolated from hamster buccal mucosa. Application of a hypotonic extracellular solution to quinacrine-positive MCs elicited a transient increase in [Ca(2+)]i. When TRPV3 channel antagonist 2,2-diphenyltetrahydrofuran was added to the hypotonic extracellular solution, however, no effect was observed on hypotonic stimulation-induced increase in [Ca(2+)]i. These results suggest that TRPV3 channels are not involved in the mechanosensory mechanism during membrane stretch in MCs.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"56 4 1","pages":"259-62"},"PeriodicalIF":0.5,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/tdcpublication.56.259","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68186899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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