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Educating the handicraft factory workers about tobacco cessation and to assess its effectiveness by motivational interviewing: An Intervention study. 手工业工厂工人戒烟教育及动机性访谈效果评估:干预研究。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Rajeev Mahajan, Jitender Solanki, Raghvendra S Kurdekar, Sarika Gupta, Ashish Modh, OmPrakash Yadav
{"title":"Educating the handicraft factory workers about tobacco cessation and to assess its effectiveness by motivational interviewing: An Intervention study.","authors":"Rajeev Mahajan,&nbsp;Jitender Solanki,&nbsp;Raghvendra S Kurdekar,&nbsp;Sarika Gupta,&nbsp;Ashish Modh,&nbsp;OmPrakash Yadav","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco use is considered to be global pandemic. The study was done to assess the effectiveness of smoking cessation intervention among workers by motivational interviewing among handicraft factories, Jodhpur, Rajasthan.</p><p><strong>Methodology: </strong>An interventional study was carried out among 400 handicraft factory workers on the basis of inclusion and exclusion criterion. Twenty one handicraft factories were taken into consideration. Training, Standardization and Calibration of Examiners was carried out in the public health department. The structured pre-tested proforma and Fagerstrom questionnaire was used to record the data. Four sessions of intervention were given to workers. Follow ups were carried out after 1 month, 3month and 6month. Paired t-test was used to compare Fagerstrom/smoking analysis mean scores among study and control groups before and after intervention.</p><p><strong>Results: </strong>showed that in study group, a percentage change of +1.2%, seen in high dependence category and -1.5 in very high dependence and after 6 months the change was+14.2%, 18.7%, -19.2% in Very low dependence, Low dependence, Medium dependence, -11.8% was seen in high dependence category and -1.8 in very high dependence. When comparison was done among Fagerstrom/smoking analysis mean scores among study subjects before and after intervention. It was found that there was a significant difference between the mean scores of Fagerstrom/smoking analysis between baseline - 3 months, 3 months to 6 months and 6 months to 9 months among study group as compared to control group.</p><p><strong>Conclusion: </strong>Tobacco addiction produces neurological and behavioural change, optima; approach involving behavioural change and pharmacotherapy are needed.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34968014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteosarcoma: A Diagnostic Dilemma. 骨肉瘤:诊断困境。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Swati Pant, Swati Tripathi, Ramakant Dandriyal, Madhusudan Astekar, Atul Joshi
{"title":"Osteosarcoma: A Diagnostic Dilemma.","authors":"Swati Pant,&nbsp;Swati Tripathi,&nbsp;Ramakant Dandriyal,&nbsp;Madhusudan Astekar,&nbsp;Atul Joshi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Osteosarcoma is a primeval disease which is still partly understood. It is a malignancy of mesenchymal cells that have the capacity to generate osteoid or immature bone. There have been an abundance of debate and controversies about the nature, aggressiveness, behavior, and various treatment modalities of this entity. Different histologic variation has been common in osteosarcoma; hence multiple diagnostic approaches are vital in all cases. Detection of precise anatomic and histologic variants is of prime importance in view of better outcome. The purpose behind writing this case report was to highlight the importance of various investigation techniques for an affirmative diagnosis.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34968567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nedaplatin and irinotecan with concurrent thoracic radiotherapy followed by docetaxel consolidation in patients with locally advanced non-small cell lung cancer. 局部晚期非小细胞肺癌患者的奈达铂和伊立替康联合胸部放疗后多西他赛巩固治疗。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Fumihiro Oshita, Shuji Murakami, Tetsuro Kondo, Haruhiro Saito, Kouzo Yamada, Yuko Nakayama
{"title":"Nedaplatin and irinotecan with concurrent thoracic radiotherapy followed by docetaxel consolidation in patients with locally advanced non-small cell lung cancer.","authors":"Fumihiro Oshita,&nbsp;Shuji Murakami,&nbsp;Tetsuro Kondo,&nbsp;Haruhiro Saito,&nbsp;Kouzo Yamada,&nbsp;Yuko Nakayama","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>We conducted a phase II study of nedaplatin (NP) and irinotecan (CPT) with concurrent thoracic radiotherapy (TRT) followed by docetaxel for locally advanced non-small cell lung cancer (NSCLC) to determine the safety and efficacy of the treatment. Patients with stage IIIA or IIIB NSCLC were treated with 3 cycles of chemotherapy comprising NP at 50 mg/m<sup>2</sup> and CPT at 50 mg/m<sup>2</sup> on days 1 and 8 every 4 weeks with concurrent TRT (2 Gy/day, total 66 Gy) followed by 3 cycles of docetaxel at 60 mg/m<sup>2</sup> on day 1 every 3 weeks.</p><p><strong>Conclusion: </strong>Fifteen patients were registered, and 8 were able to receive the entire treatment regimen. Grade 4 neutropenia and thrombocytopenia occurred in 6 and 1 patient, respectively, receiving NP and CPT with concurrent TRT. Major non-hematological toxicities were nausea, vomiting and fatigue. Grade 3 pneumonitis and esophagitis occurred in one patient each, and 4 patients developed febrile neutropenia. Docetaxel consolidation was associated with mild toxicities. Two patients died of late pulmonary failure 3 to 4 months after treatment completion, and the study was terminated. Twelve patients responded, and the median survival time, and the 1-year and 3-year survival rates were 39.3 months, 86.7% and 60.0%, respectively. In conclusion, NP and CPT with concurrent TRT is effective for patients with locally advanced NSCLC, but frequently induces pulmonary damage.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34968012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bidi smoking: an underestimated issue of Indian society. 比迪烟：印度社会一个被低估的问题。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Solanki Jitender, Gupta Sarika, Prachi Sharma, Priyanka Mishra
{"title":"Bidi smoking: an underestimated issue of Indian society.","authors":"Solanki Jitender, Gupta Sarika, Prachi Sharma, Priyanka Mishra","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Bidi smoking has always been an under-talked issue of Indian society. Bidis are rolled in tendu leaves which are non porous and have low combustibility due to which they affect the smoker's lungs even more. In spite of the increased toxicology associated with bidis, they are often ignored. The reason for this can be attributed to their home-made production, decreased taxation and the greater prevalence of bidis in rural areas. Since bidis are rolled and packed at home, packaging does not have any warnings about the harmful effects of bidi smoking. Many cases of smoking-associated cancer have been recorded in the country lately. This raises a concern about the economic balance of the nation, as to whether there is a revenue generation with tax on the sale of tobacco or if there is an economic loss due to the various diseases that result from bidi smoking.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34968571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Entering the Double Digits-Ewing Sarcoma In Adult Maxilla. 进入成人上颌骨双指-尤文氏肉瘤。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Mala Kamboj, Anju Devi, Virendra Singh, Sunita Singh
{"title":"Entering the Double Digits-Ewing Sarcoma In Adult Maxilla.","authors":"Mala Kamboj,&nbsp;Anju Devi,&nbsp;Virendra Singh,&nbsp;Sunita Singh","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Ewing sarcoma is a rare malignant pediatric sarcoma of bone and soft tissues, which is more unusual in head and neck region. Although the exact histogenesis is still unknown, various cells have been proposed as cells of origin namely, endothelial, hematopoietic, fibroblastic, mesenchymal stem cells or neural derived mesenchymal stem cells. ES is more common in younger age group and among the gnathic bones, mandible is affected more than maxilla. This paper presents the first case of Ewing Sarcoma in the maxilla being reported in the adult age group from India and among the very few reported worldwide.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34967067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Basal cell adenoma of palatal glands. 腭腺基底细胞腺瘤。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Gayathri Ramesh, Amrita Raj, Ramesh Nagarajappa, Amit Pandey
{"title":"Basal cell adenoma of palatal glands.","authors":"Gayathri Ramesh,&nbsp;Amrita Raj,&nbsp;Ramesh Nagarajappa,&nbsp;Amit Pandey","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Salivary gland neoplasms represent less than 3% of all tumors in the general population of which benign adenomas account for 65.5%. Basal cell adenoma which is classified as a subtype of monomorphic adenomas accounts for 1-2% of all salivary gland epithelial tumors, and more than 80% of them arise in the major salivary glands, mostly the parotid gland and has female predominance reporting mostly in the elderly age groups. We here report a case of basal cell adenoma of trabecular type in a male patient of age 45 years in the minor salivary glands of left posterior palatal region.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34967070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term benefit of intra-arterial bevacizumab for recurrent glioblastoma. 动脉内贝伐单抗治疗复发性胶质母细胞瘤的长期疗效。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Rachel A Alter, Timothy G White, Andrew A Fanous, Shamik Chakraborty, Christopher G Filippi, David J Pisapia, Apostolos John Tsiouris, John A Boockvar
{"title":"Long-term benefit of intra-arterial bevacizumab for recurrent glioblastoma.","authors":"Rachel A Alter,&nbsp;Timothy G White,&nbsp;Andrew A Fanous,&nbsp;Shamik Chakraborty,&nbsp;Christopher G Filippi,&nbsp;David J Pisapia,&nbsp;Apostolos John Tsiouris,&nbsp;John A Boockvar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Standard treatment for recurrent GBM is not yet established. We present a case demonstrating the benefit of intra-arterial (IA) bevacizumab with blood brain barrier disruption (BBBD) for the treatment of recurrent GBM. A 31 year-old man diagnosed with GBM, following primary resection, received temozolomide. After a second resection, he received one dose of IA bevacizumab with BBBD using mannitol, preventing regrowth for 2.5 years. Following tumor regrowth, the patient received another dose of IA bevacizumab with BBBD, which has prevented regrowth for another year.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34968568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of oxidative stress in epithelial ovarian cancer in Egyptian patients. 氧化应激在埃及上皮性卵巢癌患者中的作用。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Asmaa Ramadan, Reda Hemida, Ahmed Nowara, Laila A Eissa, Amal M El-Gayar
{"title":"Role of oxidative stress in epithelial ovarian cancer in Egyptian patients.","authors":"Asmaa Ramadan,&nbsp;Reda Hemida,&nbsp;Ahmed Nowara,&nbsp;Laila A Eissa,&nbsp;Amal M El-Gayar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Ovarian cancer has the highest mortality rate amongst all gynecologic malignancies. 90% of the cases are epithelial ovarian cancer (EOC). Ovarian cancer associated with reduction in the serum level of antioxidants super oxide dismutase (SOD) and glutathione peroxidase (GPX) and increasing in the serum level of Malondialdehyde (MDA).</p><p><strong>Objective: </strong>To find correlation between oxidative stress and epithelial ovarian cancer.</p><p><strong>Methods: </strong>In this cross-sectional study fifty-six female patients with EOC, twenty four female patients with benign ovarian tumors and ten healthy females were included in the current research study where serum level of SOD, GPX and MDA were measured.</p><p><strong>Results: </strong>Levels of SOD and GPX were found to be significantly higher in benign group when compared with malignant group (P1<0.05). There was a significant negative association between malignancy and each of SOD and GPX (p<0.05). While there was a significant positive association between malignancy and MDA (p<0.05). There was a significant negative correlation between tumor stage and level of SOD and GPX (p<0.05). Moreover, there was a significance positive correlation between tumor stage and MDA (p< 0.05).</p><p><strong>Conclusion: </strong>Patients with epithelial ovarian cancer has decreased preoperative serum level of SOD and GPX antioxidants and increased level of MDA. These findings were associated with advanced tumor stage. The study confirmed the role of oxidative stress in development of epithelial ovarian cancer.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34968010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cancer-meter: measure and cure. 癌症测量仪:测量和治疗。
Journal of Experimental Therapeutics and Oncology Pub Date : 2017-05-01
Sunil Kumar Kashyap, Birendra Kumar Sharma, Amitabh Banerjee
{"title":"Cancer-meter: measure and cure.","authors":"Sunil Kumar Kashyap,&nbsp;Birendra Kumar Sharma,&nbsp;Amitabh Banerjee","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>This paper presents a theory and system on \"Cancer-Meter'. This idea came through the statement that \"cancer is curable if it is measurable\". The Cancer-Meter proves that it is possible. This paper proposes the cancer-meter in two ways, theoretical and electronically, as per the measurement and treatment. By the mathematics, first part is defined but the second part is based on computer programming, electrical and electronics. Thus, the cancer-meter is a programmed-electrical-electronic device which measures and cures the cancer both.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34968572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple myeloma with an unusual oral presentation. 多发性骨髓瘤伴有不寻常的口头表现。
Journal of Experimental Therapeutics and Oncology Pub Date : 2016-07-01
Anjali Nayak, Meghanand T Nayak
{"title":"Multiple myeloma with an unusual oral presentation.","authors":"Anjali Nayak,&nbsp;Meghanand T Nayak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Multiple myeloma (MM) is a dyscrasia caused by neoplastic proliferation of somatically mutated plasma cells. Myeloma cells divide and expand within the bone marrow affecting multiple locations in the body where bone marrow is present. Oral manifestations, though common are usually not diagnosed. This report describes rare oral manifestations of multiple myeloma like oral petechiae and gingival swelling presented in a 40-year-old male patient. The diagnosis was established by blood examination & skeletal survey, while oral findings were later correlated with the diagnosis of MM. A brief review on MM is presented along with the demonstration of rare oral manifestations.</p>","PeriodicalId":45335,"journal":{"name":"Journal of Experimental Therapeutics and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34966191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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