Journal of Clinical Neonatology最新文献

{"title":"Effect of light-emitting diode phototherapy on serum electrolyte levels in neonates with unconjugated hyperbilirubinemia: A prospective single-center study","authors":"Naadia Nazim, B. Gaur, F. Ahmad, B. Maini, Rupa R Singh","doi":"10.4103/jcn.jcn_42_23","DOIUrl":"https://doi.org/10.4103/jcn.jcn_42_23","url":null,"abstract":"Background: Neonatal unconjugated hyperbilirubinemia (NUH) is one of the common morbidities found in the 1st week of life. Phototherapy has been found to be the safest of all the known treatments for neonatal jaundice. Light-emitting diode phototherapy does, however, have some side effects, just like any other therapeutic approach. Objectives: We aimed to study the effect of light-emitting diode phototherapy and their duration on the serum electrolyte (serum sodium, potassium, chloride, and calcium) levels in neonates with unconjugated hyperbilirubinemia (UH) and to study the effect of phototherapy modes on them. Materials and Methods: All stable icteric neonates, gestational age >35 weeks, who received phototherapy for UH were included in the study. A double-surface light-emitting diode phototherapy system (spectrum 430–470 nm) was used. These neonates were subjected to different phototherapy modes: normal and intensive. Total serum bilirubin and serum electrolytes were measured at the start and the end of phototherapy. Paired t-test, independent t-test, and Chi-square test were used for the comparisons. Results: A total of 100 neonates were admitted for phototherapy. The male: female ratio was 1.08:1. The mean birth weight, mean gestational age, mean age, and mean duration of phototherapy of jaundiced neonates were 2.50 ± 0.603 kg, 36.8 ± 2.04 weeks, 2.56 ± 1.05 days, and 29.34 ± 6.51 h, respectively. The mean Na, K, Cl, and Ca levels before phototherapy were 140.10 ± 14.88 meq/L, 4.51 ± 0.55 meq/L, 105.65 ± 6.53 meq/L, and 8.90 ± 0.55 mg/dl and after phototherapy were 139.62 ± 5.38 meq/L, 4.36 ± 0.48 meq/L, 103.89 ± 6.85 meq/L, and 8.33 ± 0.72 mg/dl, respectively (P < 0.001). The duration of phototherapy was found to correlate with serum Ca levels significantly negative (P < 0.05). Conclusion: This study shows that serum electrolyte levels were significantly decreased during light-emitting diode phototherapy. These levels were affected more by the duration of phototherapy than by its mode. Phototherapy-induced dyselectrolytemia is a significant concern, as electrolyte abnormalities result in severe short-term and long-term adverse effects.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"79 - 85"},"PeriodicalIF":0.2,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45021283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of parents regarding care of neonate undergoing phototherapy","authors":"Sneha Raut, Bhagyashree A. Jogdeo, S. Joshi","doi":"10.4103/jcn.jcn_5_23","DOIUrl":"https://doi.org/10.4103/jcn.jcn_5_23","url":null,"abstract":"Background: Neonatal jaundice is the most common problem in the 1st week of the neonate. About 60% of neonates are diagnosed with neonatal jaundice visibly in the 1st week of life. About 5%–10% of neonates have clinical significance requiring phototherapy or other treatment. Jaundice is caused by bilirubin deposition in the skin. Objective: The objective of this study was to assess the level of knowledge among parents regarding the care of neonates undergoing phototherapy, and to assess the effectiveness of the information booklet. Materials and Methods: In the present study, the researcher adopted a quasi-experimental pretest, posttest control group design. The sample size was 120, control group 60, and experimental group 60. Nonprobability purposive sampling technique was used to collect the data. Researcher used prevalidated structured questionnaire. The average time taken by each sample for answering the question was 15–20 min. Data analysis was done mainly using descriptive and inferential statistics. Results: The findings show that knowledge among parents of neonates regarding care of phototherapy in the pretest 71.67% sample were having good knowledge, 25% were having poor knowledge, and 3.33% sample were having excellent knowledge. In the posttest experimental, 70% sample were having excellent knowledge. Conclusion: The study shows that the knowledge of the parents improved substantially after the administration of the information booklet. No association was found with any of the demographic variables.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"60 - 64"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48947207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic clues for pneumoperitoneum in premature infants through ultrasonography: Two newborn cases","authors":"Tugay Tepe, M. Ozdemir, M. Konak, H. Soylu","doi":"10.4103/jcn.jcn_3_23","DOIUrl":"https://doi.org/10.4103/jcn.jcn_3_23","url":null,"abstract":"Pneumoperitoneum (PP) is a life-threatening condition that requires urgent intervention depending on etiology. Besides traditional methods for detecting free air in the abdominal cavity, abdominal ultrasonography may be an alternative tool for diagnosing intestinal injuries. We report two premature infants with PP diagnosed through bedside abdominal ultrasonography (BAUS). The first case was an extremely low-birth weight infant with PP due to necrotizing enterocolitis. The second case was 35 gestational-aged premature infants who had sudden abdominal distension. Abdominal ultrasonography use is trending in follow-up, especially in intensive care units and emergency departments. It is important to perform BAUS serially as a part of point-of-care ultrasonography application and consider with the physical examination in high-risk infants.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"72 - 74"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46650928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of nucleated red blood cells in diagnosis and prognosis of asphyxia in preterm neonates","authors":"M. Zakerihamidi, A. Moradi, F. Bagheri, H. Boskabadi","doi":"10.4103/jcn.jcn_97_22","DOIUrl":"https://doi.org/10.4103/jcn.jcn_97_22","url":null,"abstract":"Introduction: Nucleated red blood cell (NRBC) count can be used as a simple indicator for evaluation of the severity and primary outcomes of perinatal asphyxia. The current study has aimed to define the predictive value of NRBC count in the diagnosis and outcomes of preterm neonates with asphyxia. Materials and Methods: This cohort study was performed on 353 preterm (gestational age <37 weeks) neonates (168 asphyxia [47.6%] and 185 nonasphyxia [52.4%] neonates) from 2017 to 2021. The neonatal data were recorded. Denver II test was performed at 6, 12, 18, and 24-month follow-up visits. The children were then categorized into two groups of favorable and nonfavorable outcomes (death or developmental delay). Results: NRBC count and NRBC/100 white blood count (WBC) in asphyxia preterm neonates (30 ± 69.6 × 102/mm3 and 9.6 ± 11.2) were significantly higher than nonasphyxia preterm neonates (32.3 ± 54.4 × 102/mm3 and 7.6 ± 9) (P < 0.001). Furthermore, NRBC count and NRBC/100 WBC in preterm asphyxia neonates with unfavorable outcomes (29.2 ± 52.4 × 102/mm3 and 32.17 ± 80.8 × 102/mm3) were significantly higher than those with normal outcomes (15 ± 30.4 × 102/mm3 and 10.14 ± 19.17 × 102/mm3) (P < 0.001). NRBC count >370 had sensitivity and specificity of 69.5% and 57.3%, whereas NRBC/100 WBC >8% had sensitivity and specificity of 63.2% and 63.6% in diagnosing asphyxia in preterm neonates. Furthermore, NRBC count >370 had sensitivity and specificity of 72.6% and 53.8%, whereas NRBC/100 WBC >8% had sensitivity and specificity of 70.5% and 65.1% for the prognosis of asphyxia preterm neonates. Conclusions: According to our findings, NRBC/100 WBC >370 and total NRBC >8% are suitable sensitive predictors of the prognosis of preterm neonates with asphyxia. Evaluation of NRBC count and NRBC/100 WBC can help in the diagnosis of asphyxia and prognosing unfavorable outcomes of asphyxia in asphyxia preterm neonates.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"47 - 52"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43535112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of cytomegalovirus infections in blood donors and the newborn versus utility of leukocyte-reduced blood transfusion in the premature newborn: An observation from Eastern India","authors":"Arijit Das, Dinesh Munian, Chikam Maity, Sumita Pandey, Sandip Paul, P. Bhattacharya","doi":"10.4103/jcn.jcn_8_23","DOIUrl":"https://doi.org/10.4103/jcn.jcn_8_23","url":null,"abstract":"Purpose and Objectives: Leukocyte-reduced blood components prevent the transmission of cytomegalovirus (CMV) infection; however, provision of universal leukoreduced blood involves a huge resource constraint to developing countries. The present study aimed to identify the seroprevalence of CMV among voluntary blood donors and newborns who were transfused with nonleukoreduced blood in the recent past (control). With the availability of leukoreduced blood, the pre- and posttransfusion CMV serology was analyzed in the newborn (cohort) who had received entirely leukoreduced blood to understand its utility. Methods: Eight hundred and fifty-two healthy blood donors and 40 newborns (control) who received nonleukoreduced blood in the recent past were observed for the seroprevalence of CMV. In the other arm, 45 newborns (premature) were transfused with leukoreduced blood and observed for CMV seroprevalence during both pre- and posttransfusion periods. To identify the evidence of recent infection in these population, CMV immunoglobulin G (IgG) avidity was performed in a proportion of the participants in all the groups. Quality control of the leukoreduced blood components was also checked as per standards. Results: The overall seroprevalence of CMV in blood donors, posttransfused newborns (control), and the cohort group was high. In the blood donors, a limited number of CMV IgG avidity tests showed a high infectivity rate (85.19%). A similar result was also observed in the newborn population in both the groups for recent CMV infections. Conclusion: The present study showed a high prevalence of CMV infections in blood donors and newborns. The leukoreduced blood transfusion might be effective for preventing other serious adverse outcomes except CMV.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"65 - 71"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42557200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional intelligence and neonatal intensive care unit","authors":"S. Manzar","doi":"10.4103/jcn.jcn_12_23","DOIUrl":"https://doi.org/10.4103/jcn.jcn_12_23","url":null,"abstract":"","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"77 - 78"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42246216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted individualized versus standardized preterm human breast milk fortification: A randomized controlled trial","authors":"A. Ahuja, Temjen Longkumer, Deepa Sikriwal, R. Mallaiah","doi":"10.4103/jcn.jcn_111_22","DOIUrl":"https://doi.org/10.4103/jcn.jcn_111_22","url":null,"abstract":"Introduction: Extrauterine growth retardation (EUGR) is one of the major problems faced in most preterm neonates. The only way to prevent EUGR is by providing adequate amount of calories through fortification of human breast milk. Human milk fortification (HMF) is now considered a standard practice to prevent EUGR in most of the neonatal units. We compared targeted individualized fortification (TIF) versus standardized fortification (SF) of breast milk with HMF to assess catch-up growth in preterm neonates. Materials and Methods: We conducted a prospective randomized control study at a tertiary neonatal intensive care unit in urban India for 1 year. Appropriate for gestational age neonates ≤32 weeks of gestation or with birth weight ≤1800 g were enrolled and followed up for 50 corrected weeks for the assessment of catch-up growth. Results: A total of 32 infants were enrolled; 25 neonates completed the study (TIF: n = 13; SF: n = 12). The mean birth weight and head circumference were 1268.76 g and 27.23 cm in the TIF group and 1172.83 g and 26.58 cm in the SF group, respectively (both P > 0.05). At the end of the study, catch-up growth for weight was achieved by 10 (77%) neonates in the TIF group and 2 (17%) neonates in the SF groups. Similarly, catch-up growth for head circumference was achieved by 7 (54%) and 1 (8%) neonates in the TIF and SF groups, respectively. However, there was a significant difference in weight (P = 0.00071) and head circumference (P = 0.001752) in the TIF group at the end of the study. Conclusion: TIF is feasible in clinical practice. In preterm neonates, it helps in achieving catch-up growth faster and may decrease the rates of EUGR.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"53 - 59"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47000956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons learned from the first hospital-wide neonatal resuscitation program mock code: Enhancing patient safety in neonatal resuscitation","authors":"A. Almudeer, I. Taha, Mohammed Alarifi, M. Temsah","doi":"10.4103/jcn.jcn_10_23","DOIUrl":"https://doi.org/10.4103/jcn.jcn_10_23","url":null,"abstract":"","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"75 - 76"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47705382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual course of pneumonia in a term neonate with suspected multisystem inflammatory syndrome secondary to severe acute respiratory syndrome coronavirus 2 infection","authors":"Ashish Ragireddy, R. Das, B. Mallick, Debasish Nanda","doi":"10.4103/jcn.jcn_96_22","DOIUrl":"https://doi.org/10.4103/jcn.jcn_96_22","url":null,"abstract":"Neonatal multisystem inflammatory syndrome secondary to severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection is a relatively new entity with only a few cases being reported in the literature. We report the case of a 25-day-old term neonate who presented with severe respiratory distress, required respiratory support, and systemic antibiotics at admission. Two-dimensional echocardiography revealed the features of pulmonary arterial hypertension. Computed tomography scan of the chest was suggestive of features of organizing pneumonia. In view of multisystem involvement, raised inflammatory markers, and high anti-SARS-CoV2 antibody, intravenous immunoglobulin was administered, following which the baby improved and weaned off to room air and eventually discharged.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"34 - 37"},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46272226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes, and perceptions of health-care workers about human milk banking in Singapore","authors":"N. Koh, C. Chien, S. Saffari, R. Samuel","doi":"10.4103/jcn.jcn_99_22","DOIUrl":"https://doi.org/10.4103/jcn.jcn_99_22","url":null,"abstract":"Background: The use of human milk provides substantial short- and long-term benefits. With the establishment of the first donor human milk bank in Singapore, high-risk preterm and critically ill infants whose mothers have an inadequate milk supply can have access to pasteurized donor human milk. Materials and Methods: A self-administered anonymous questionnaire was conducted among doctors and nurses working in the special care unit and neonatal intensive care unit of KK Women's and Children's Hospital. The questionnaire was divided into three main sections, namely, demographics, knowledge assessment, and opinion. The aims of the survey were to assess the knowledge, attitudes, and perceptions of health-care workers on breast milk donation and milk bank, and to identify any differing perceptions among different racial and ethnic groups. Results: A total of 38 doctors and 140 nurses from various racial and religious backgrounds participated in this survey. More than 50% of respondents know the benefits of breast milk over formula milk; however, knowledge of the milk donation process and the effect of pasteurization on donated breast milk can be improved on. In the opinion section, 78.7% of survey respondents were supportive of the human milk bank. Sixty-eight (38.2%) respondents felt that recipients should receive milk from donors of the same race and ethnicity, whereas 56 (31.5%) disagreed and 53 (30%) were neutral. Conclusion: Donor human milk banking is well received and supported by health-care workers. Knowledge of milk donation, screening, pasteurization, and storage can be improved on. Further evaluation is required to determine the underlying concerns that different ethnic groups may have.","PeriodicalId":45332,"journal":{"name":"Journal of Clinical Neonatology","volume":"12 1","pages":"22 - 26"},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48414171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}