Clinics and Practice最新文献

{"title":"Assessment of the Effect of Kinesiology Taping on Scar Treatment in Children.","authors":"Justyna Pogorzelska, Agata Michalska, Anna Zmyślna","doi":"10.3390/clinpract15070131","DOIUrl":"10.3390/clinpract15070131","url":null,"abstract":"<p><p><b>Background</b>: The consequences of injuries resulting from accidents are among the most common health disorders in children. A scar forms at the site of the injury. In the treatment of scars, not all methods used in adults can be used in children. The authors attempted to assess the effectiveness of using KT kinesiology taping on scars in children. The aim of the work is to assess the effect of KT on the treatment of keloid, hypertrophic scars, and postoperative adhesions in children. <b>Methods</b>: The study included 30 patients aged 4 to 10 years. The subjects were divided into three groups: group G1-9 patients with keloid scars, group G2-14 with hypertrophic scars, group G3-7 with postoperative adhesions. The patients underwent kinesiology taping for 8 weeks. The analyzed parameters were determined using the VSS scale and ultrasonography. <b>Results</b>: The analysis of the VSS scale results in relation to the type of scars showed a significant (<i>p</i> < 0.001) downward trend in the measured parameters for keloid and hypertrophic scars. Analysis of ultrasound results in relation to the type of scars showed a significant (<i>p</i> < 0.001) downward trend in the measured parameters, comparing parameters I and II for all types of scars. <b>Conclusions</b>: Kinesiology taping significantly changes the following scar parameters: deformability, pigmentation, and perfusion in the case of keloid and hypertrophic scars.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic Fractures in Adults and the Importance of Associated Injuries-A Current Multi-Disciplinary Approach.","authors":"Jakub Ohla, Piotr Walus, Michał Wiciński, Bartłomiej Małkowski, Bartosz Turoń, Adam Jabłoński, Michał Gawryjołek, Katie Kellett, Jan Zabrzyński","doi":"10.3390/clinpract15070130","DOIUrl":"10.3390/clinpract15070130","url":null,"abstract":"<p><strong>Background: </strong>Pelvic ring fractures are a significant and growing health problem in the field of trauma and orthopedic surgery. The aim of this paper was to present a concise description of these musculoskeletal injuries, available classification systems, and vascular and genitourinary complications.</p><p><strong>Results: </strong>The most common complications of serious pelvic ring fractures are arterial and venous hemorrhages, as well as urethral injuries. Arterial hemorrhages most often originate from the trunk or branches of the iliac artery, and the standard treatment is pelvic stabilization and implementation of intravascular procedures. In the case of venous hemorrhages, peritoneal pelvic packing is the most important.</p><p><strong>Conclusions: </strong>A multi-disciplinary approach and treatment algorithmization are important to facilitate the prioritization of therapeutic procedures. Treatment of patients with pelvic ring fractures should take place in specialized trauma centers.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12294093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Activity in Mental Health Treatment: Clinician Perspectives and Practices.","authors":"Madeline Crichton, Barbara Fenesi","doi":"10.3390/clinpract15070129","DOIUrl":"10.3390/clinpract15070129","url":null,"abstract":"<p><p><b>Background/Objectives</b>: The beneficial effects of physical activity on mental health and well-being are well established. The integration of physical activity into psychotherapeutic treatment for mental health difficulty holds promise as an avenue to reduce symptoms and support well-being. Mental health clinicians have previously indicated an interest in the use of physical activity in treatment, but it is unclear to what extent physical activity interventions are implemented in clinical mental health care. The present study aimed to understand mental health clinicians' practices related to physical activity, as well as to investigate their related training and knowledge. <b>Methods</b>: Semi-structured interviews were conducted with mental health clinicians, including registered psychologists, psychotherapists, and social workers. Inductive content analysis was performed to identify key themes related to practices, training experiences, and training interests. <b>Results</b>: Clinicians reported making recommendations for physical activity and using a range of in-session strategies to include physical activity in mental health treatment. Clinicians reported that their knowledge and training about physical activity was obtained primarily from informal sources. Clinicians indicated an interest in further training, with an emphasis on practical strategies. <b>Conclusions</b>: Mental health clinicians demonstrated an interest in the use of physical activity as part of psychotherapeutic treatment. Some clinicians routinely integrate physical activity into treatment, while others express a need for further training in this area.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Series on the Efficacy of the Pharmacological Treatment of Lipedema: The Italian Experience with Exenatide.","authors":"Laura Patton, Valeria Reverdito, Alessandra Bellucci, Micaela Bortolon, Annalisa Macrelli, Lorenzo Ricolfi","doi":"10.3390/clinpract15070128","DOIUrl":"10.3390/clinpract15070128","url":null,"abstract":"<p><p><b>Background:</b> Lipedema is a chronic disease of subcutaneous adipose tissue that predominantly affects women and is frequently associated with endocrinopathies such as insulin resistance and obesity. Its pathogenesis is still unclear, and treatment, which requires a multi-disciplinary approach, is prolonged over time and is not always effective. There is currently no drug treatment available for this disease. <b>Methods:</b> Five different cases of women with lipedema and insulin resistance, treated with Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) and once-weekly exenatide, in association or not with lifestyle changes (diet or physical activity) for 3 to 6 months are described. Changes in anthropometric parameters, symptoms, clinical findings and the thickness of superficial adipose tissue measured by ultrasound were evaluated. <b>Results:</b> Treatment with exenatide, whether combined with a change in diet or physical activity, resulted in a reduction in the characteristic symptoms of lipedema, in pain evoked by pinching the adipose tissue fold and in the thickness of subcutaneous adipose tissue at the levels of the lower limbs, abdomen and upper limbs. In four out of five cases, a reduction in body weight was observed, particularly during the first three months of treatment and in cases with greater metabolic impairment. Clinical, instrumental and subjective improvements were also observed in cases where there was no reduction in body weight and in patients who had previously undergone lower limb liposuction. <b>Conclusions:</b> The improvement in symptoms and clinical signs of lipedema, in addition to the reduction in adipose tissue in patients with lipedema and insulin resistance with exenatide, suggests a novel pharmacological approach to the disease, which can be combined with other conservative and surgical treatments to promote weight reduction. These results also highlight the association of this disease with metabolic alterations and the fundamental role of an accurate diagnosis followed by the treatment of comorbidities and excess weight in these patients.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preeclampsia as a Risk Factor of Postmenopausal Cardiovascular Disease: A Cross-Sectional Study.","authors":"Pasquale Palmiero, Pierpaolo Caretto, Francesca Amati, Marco Matteo Ciccone, Maria Maiello","doi":"10.3390/clinpract15070126","DOIUrl":"10.3390/clinpract15070126","url":null,"abstract":"<p><p><b>Introduction:</b> Preeclampsia (PE) is a pregnancy-specific disorder characterized by hypertension and organ dysfunction, affecting 5-8% of pregnancies globally and increasing women's long-term risk of cardiovascular disease (CVD). This study investigates the association between prior PE and cardiovascular health in postmenopausal women. <b>Methods:</b> A total of 108 postmenopausal women with a history of PE and 100 controls without PE were enrolled. Clinical data, blood pressure readings, and echocardiographic assessments were obtained. Statistical analysis was conducted using SPSS version 20.0. <b>Results:</b> Women with prior PE showed a higher prevalence of eccentric left ventricular hypertrophy (37% vs. 23%, <i>p</i> < 0.02) and diastolic dysfunction (51% vs. 39%, <i>p</i> < 0.003). Maternal history of hypertension was also more common in the PE group (55% vs. 26%, <i>p</i> < 0.003). Obesity was more frequent in the PE group, but did not reach statistical significance (<i>p</i> < 0.09). <b>Conclusions:</b> Prior PE was linked to an increased risk of postmenopausal cardiac abnormalities, including left ventricular hypertrophy and diastolic dysfunction. A maternal history of hypertension was also more common among women with prior PE, suggesting a familial connection; PE should be acknowledged as a significant predictor of long-term cardiovascular risk, requiring lifelong monitoring and preventive measures.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial Effect of Platelet-Rich Fibrin as an Adjunct to Nonsurgical Therapy After Subgingival Professional Mechanical Plaque Removal for Periodontitis: A Systematic Review and Meta-Analysis.","authors":"Monica Tanady, Fatimah Maria Tadjoedin, Sri Lelyati C Masulili, Nadhia Anindhita Harsas, Adityo Widaryono","doi":"10.3390/clinpract15070127","DOIUrl":"10.3390/clinpract15070127","url":null,"abstract":"<p><p><b>Background and Objectives:</b> Periodontitis is an inflammatory disease that compromises the supporting structures of the teeth, leading to irreversible tissue damage and tooth loss. While subgingival professional mechanical plaque removal (PMPR) remains the gold standard treatment, there is increasing interest in adjunctive therapies. Platelet-rich fibrin (PRF) has gained attention as a promising biomaterial to enhance periodontal healing and regeneration. This study aimed to evaluate the clinical and immunological effectiveness of PRF as an adjunct to PMPR. <b>Materials and Methods:</b> Clinical studies published between January 2019 and August 2024 were included from the ProQuest, PubMed, PMC, ScienceDirect, Scopus, and EBSCO databases. Seven studies met the inclusion criteria, focusing on adults with periodontitis treated with PRF + PMPR compared to PMPR alone. Primary outcomes included changes in clinical and immunological parameters. Risk of bias was assessed using the Cochrane ROB2 tool. Meta-analysis was conducted using both fixed-effect and random-effects models, depending on heterogeneity. <b>Results:</b> The meta-analysis demonstrated significant improvements in clinical outcomes in the PRF + PMPR group, with reductions in probing pocket depth (SMD: -1.43 mm; 95% CI: -2.05 to -0.81; <i>p</i> < 0.00001), clinical attachment level (SMD: -1.34 mm; 95% CI: -1.95 to -0.73; <i>p</i> < 0.0001), bleeding on probing (SMD: -0.75 mm; 95% CI: -1.11 to -0.39; <i>p</i> < 0.00001), gingival recession (SMD: -0.79 mm; 95% CI: -1.33 to -0.25; <i>p</i> = 0.004), and gingival index (SMD: -0.82 mm; 95% CI: -1.37 to -0.28; <i>p</i> = 0.003). Favorable trends were also observed in IL-10, TGF-β, VEGF, PDGF-BB, periostin, and type I collagen levels. <b>Conclusions:</b> PRF enhances clinical and immunological outcomes and supports periodontal tissue stability when used as an adjunct to non-surgical therapy.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Effects of Multiple Ischemic Compression Applications on Pain Sensitivity and Biomechanical Properties of Myofascial Trigger Points.","authors":"Sebastian Szajkowski, Jarosław Pasek, Grzegorz Cieślar","doi":"10.3390/clinpract15070125","DOIUrl":"10.3390/clinpract15070125","url":null,"abstract":"<p><p><b>Background:</b> Myofascial trigger points (MTrPs) are hyperirritable spots within taut bands of skeletal muscle fibers, often developing in overloaded muscles. Ischemic compression (IC) is a frequently used therapeutic technique for MTrP treatment. <b>Material and Methods:</b> Seventy-nine participants with MTrPs in the upper trapezius muscle were included. Three IC protocols were used. In group 1, the compression force was increased once; in group 2, twice; and in group 3, three times-each time up to the pain threshold, then held constant until the pain subsided. Evaluations included pressure pain threshold (PPT), pressure pain perception (PPP), and myotonometric measurements. <b>Results:</b> PPT values increased significantly in group 2 (<i>p</i> = 0.009) and group 3 (<i>p</i> = 0.009), while PPP values decreased significantly in both groups (group 2: <i>p</i> = 0.016; group 3: <i>p</i> = 0.041) post-intervention. Group 1 showed a significant reduction in muscle tone (<i>p</i> < 0.001), and group 2 in muscle stiffness (<i>p</i> = 0.036). Muscle elasticity significantly improved in all groups: group 1 (<i>p</i> = 0.022), group 2 (<i>p</i> = 0.001), and group 3 (<i>p</i> = 0.042). <b>Conclusions:</b> IC applied with a constant force at the individual's pain perception threshold effectively elevates the pain threshold and enhances the biomechanical parameters of muscle fibers in the trigger point area.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Passive Immunity: Three Neonatal Influenza Cases Highlighting Impact of Missed Maternal Vaccination.","authors":"Irina Profir, Cristina-Mihaela Popescu, Gabriel Valeriu Popa, Aurel Nechita","doi":"10.3390/clinpract15070124","DOIUrl":"10.3390/clinpract15070124","url":null,"abstract":"<p><p><b>Background</b>: Neonatal influenza is a rare condition. Young infants have immature immune defenses and are unable to receive direct vaccination; this can result in significant illness. Maternal anti-influenza immunization during pregnancy provides passive antibodies to the newborn via transplacental transfer, significantly decreasing the incidence and severity of influenza in early infancy. Nevertheless, the vaccination coverage during pregnancy remains low in many regions, leaving certain neonates without adequate protection. <b>Methods</b>: We present three cases of laboratory-confirmed influenza infection in neonates admitted to the \"Sf. Ioan\" Clinical Emergency Pediatric Hospital in Galați and conduct a literature review. The clinical presentation, co-infections, timing of antiviral therapy, laboratory findings, maternal vaccination status, and outcomes (including the hospitalization duration and recovery) were systematically analyzed for each case. <b>Results</b>: All three neonates were full-term and previously healthy, born to mothers who had not received influenza vaccinations during their pregnancies. They presented at ages ranging from 2 to 4 weeks with fever, respiratory symptoms including a cough, nasal congestion, and respiratory distress, as well as feeding difficulties. One case involved a co-infection with Bordetella pertussis, which manifested as a severe paroxysmal cough, cyanosis, and apnea. Laboratory findings in the cases with influenza alone indicated leukopenia accompanied by normal C-reactive protein levels. In the co-infection case, leukocytosis, lymphocytosis, and thrombocytosis were observed. All the infants received oseltamivir treatment within 48 h of the symptom onset; the case with pertussis co-infection also received azithromycin. Each infant required supplemental oxygen, but none necessitated mechanical ventilation. Clinical improvement was observed in all cases, with hospitalization ranging from 6 to 7 days and complete recovery without complications. <b>Conclusions</b>: Neonatal influenza may result in considerable morbidity, particularly in infants born to unvaccinated mothers. Positive outcomes, however, have been correlated with early diagnosis and antiviral treatment. Pertussis co-infection may exacerbate clinical progression, underscoring the importance of maternal immunization against both influenza and pertussis. In this case series, we aim to present three cases of laboratory-confirmed influenza in neonates born to mothers who were not immunized against influenza during pregnancy. These cases highlight the clinical presentations of neonatal influenza, underscore the risks associated with pertussis co-infection, and reinforce the importance of maternal influenza and Tdap vaccination for preventing severe outcomes in newborns.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking the Subjective Units of Distress Scale: Validity and Clinical Utility of the SUDS.","authors":"Elizabeth Mattera, Brian Zaboski","doi":"10.3390/clinpract15070123","DOIUrl":"10.3390/clinpract15070123","url":null,"abstract":"<p><p>The Subjective Units of Distress Scale (SUDS) is a widely used self-report measure clinicians rely on during exposure and response prevention (ERP) to monitor progress, guide exposure pacing, and assess intervention efficacy. However, despite its ubiquity in clinical and research settings, foundational investigations of its psychometrics are often atheoretical, fail to evaluate its longitudinal properties, and lack a rigorous construct validation framework. This paper addresses these shortcomings by evaluating the SUDS as a measure of state negative affective intensity using the Strong Program of Construct Validation. Our evaluation demonstrates that the SUDS suffers from significant psychometric weaknesses, including construct underrepresentation, construct irrelevance, poorly defined measurement occasions, and structural limitations, challenging its validity as a precise measure of subjective distress. These limitations have crucial implications for clinical practice, potentially leading to misinterpretations of patient distress and compromising treatment decisions. We discuss these clinical implications, highlight them with a brief clinical vignette, outline a research roadmap for potential improvement using modern psychometric methods, and provide practical recommendations for clinicians currently using the SUDS. Given these validity concerns, caution is warranted when interpreting SUDS scores in both clinical and research contexts until its psychometric properties are more robustly established and understood.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Survival and Prognostic Factors in Patients Undergoing Liver Resection for Primary Hepatic Carcinoma-A Follow-Up Study.","authors":"Unenbat Gurbadam, Gantuya Dorj, Aryabilig Otgongerel, Munkhtsetseg Janlav, Serod Khuyagaa, Tsenguun Ganbat, Tserendorj Demchig, Amgalantuul Batdelger, Batsaikhan Bayartugs, Munkhdelger Byambaragchaa, Yerbolat Amankeldi, Munkhzaya Chogsom, Chinburen Jigjidsuren, Bayart-Uils Bayar, Lkham Nyam-Osor","doi":"10.3390/clinpract15070121","DOIUrl":"10.3390/clinpract15070121","url":null,"abstract":"<p><p><b>Background:</b> Mongolia has a high incidence of hepatocellular carcinoma (HCC), with 85.6 cases per 100,000 population and 70% diagnosed at an advanced stage. HCC accounts for 35% of all cancer-related deaths in the country. The primary treatment for HCC remains hepatotectomy. This study aims to investigate the factors affecting the prognosis of patients undergoing liver resection for HCC in Mongolia. <b>Materials and Methods:</b> A retrospective cohort study was conducted using data from the National Cancer Centre's eHealth program and cancer registry. The study enrolled 1100 patients who underwent liver resection from 2015 to 2018, with a follow-up period of 5.25-9.25 years to determine survival rates. <b>Results:</b> The study included 980 patients, with a male-to-female ratio of 1.2:1 and an average age of 60 years. Tumour stage II patients had the highest survival rate (46.55%), and those with stage IIIb had the lowest (1.51%) (<i>p</i> = 0.0001). Smaller tumours (≤5 cm) were associated with better survival (<i>p</i> = 0.0006). Histologically, 19.4% had liver cirrhosis, and 80.7% had liver fibrosis. The preoperative median AFP level was 23.9 ng/mL (range 0-121,000 ng/mL). The average survival time post-liver resection was 6.675 years (<i>p</i> = 0.0006). Factors such as blood loss (<i>p</i> = 0.0004), vascular invasion (MaVI-<i>p</i> < 0.0001, MVI <i>p</i> = 0.0011), tumour size ≤ 5 cm (<i>p</i> = 0.0007), and elevated AST and ALT levels significantly influenced long-term survival (<i>p</i> = 0.0004, respectively). <b>Conclusions:</b> The study identified key prognostic factors influencing survival rates in HCC patients post-liver resection. Minimising blood loss, early detection, and managing vascular invasion, along with early-stage detection and treatment, are crucial for improving patient outcomes.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"15 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12293281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}