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Risk Factors and Comorbidities in Young Indian Patients with Hypertension: REAL YOUNG (Hypertension) Study. 印度年轻高血压患者的危险因素和合并症:REAL Young(高血压)研究
IF 2.2
Integrated Blood Pressure Control Pub Date : 2021-02-26 eCollection Date: 2021-01-01 DOI: 10.2147/IBPC.S272548
Nagaraj Desai, Govindan Unni, Rajeev Agarwala, Santosh Salagre, Sanjay Godbole, Ashish Dengra, Mahesh V Abhyankar, Santosh Revankar
{"title":"Risk Factors and Comorbidities in Young Indian Patients with Hypertension: REAL YOUNG (Hypertension) Study.","authors":"Nagaraj Desai,&nbsp;Govindan Unni,&nbsp;Rajeev Agarwala,&nbsp;Santosh Salagre,&nbsp;Sanjay Godbole,&nbsp;Ashish Dengra,&nbsp;Mahesh V Abhyankar,&nbsp;Santosh Revankar","doi":"10.2147/IBPC.S272548","DOIUrl":"https://doi.org/10.2147/IBPC.S272548","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the risk factors and comorbidities among the young Indian adults with hypertension.</p><p><strong>Patients and methods: </strong>This was a retrospective, multicentric real-world study which included patients diagnosed with and receiving treatment for hypertension. Data were collected from the medical records of clinics/hospitals across 623 study sites in India. Patients of either sex and aged 18-45 years were included. Demographic details (age, sex, anthropometric measurement), medical and family history, sedentary lifestyle, smoking status and alcohol consumption data were extracted. Descriptive and comparative analysis (Mann-Whitney <i>U</i> and chi-squared test) was done.</p><p><strong>Results: </strong>Out of 15,006 young patients diagnosed with hypertension (men=63.6%), 65.7% belonged to the age group of >35-45 years. The median body mass index was 27.0 kg/m<sup>2</sup>. Patients diagnosed with only hypertension were 29.1% while other predominant comorbidities with hypertension were diabetes mellitus (42.4%) and dyslipidemia (7.8%). Hypertension with diabetes mellitus were prevalent in the age group of >35-45 years (43.8%). More than half of the patients with hypertension (n=7656) had a sedentary lifestyle. Overall, 35.6%, 47.3%, and 56.7% of the patients were alcoholic, smokers (present and former), and had a family history of hypertension, respectively.</p><p><strong>Conclusion: </strong>The results showed that among the young population, hypertension was common in the age group of >35-45 years and diabetes mellitus and dyslipidemia were common comorbidities. Family history, sedentary lifestyle, smoking, alcohol consumption, and body mass index may also contribute to hypertension.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"14 ","pages":"31-41"},"PeriodicalIF":2.2,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d3/27/ibpc-14-31.PMC7924245.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25431615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Are Community Health Center Patients Interested in Self-Measured Blood Pressure Monitoring (SMBP) - And Can They Do It? 社区卫生中心的病人对自我测量血压监测(SMBP)感兴趣吗?他们能做到吗?
IF 2.2
Integrated Blood Pressure Control Pub Date : 2021-02-12 eCollection Date: 2021-01-01 DOI: 10.2147/IBPC.S285007
Debosree Roy, Margaret Meador, Nana Sasu, Kate Whelihan, Joy H Lewis
{"title":"Are Community Health Center Patients Interested in Self-Measured Blood Pressure Monitoring (SMBP) - And Can They Do It?","authors":"Debosree Roy,&nbsp;Margaret Meador,&nbsp;Nana Sasu,&nbsp;Kate Whelihan,&nbsp;Joy H Lewis","doi":"10.2147/IBPC.S285007","DOIUrl":"https://doi.org/10.2147/IBPC.S285007","url":null,"abstract":"<p><strong>Introduction: </strong>Self-measured blood pressure monitoring (SMBP) helps diagnose and manage hypertension from outside the clinic, which has implications for patient empowerment and outcomes, continuity of care, and resilience in care communities catering to vulnerable populations.</p><p><strong>Methods: </strong>We instituted a protocol for SMBP among hypertensive patients at 9 community health centers in 3 states and administered questionnaires to patients before and after the protocol was instituted to assess knowledge and engagement with disease management, beliefs and attitudes towards, and experience doing SMBP. Questionnaires included 16 items designed to evaluate patient perceptions and beliefs about SMBP. These included a series of questions using a 5-point Likert scale, binary questions related to their perceived ability to comply with specific SMBP guidelines and open-ended questions to obtain descriptions of experiences with SMBP.</p><p><strong>Results: </strong>The pre-questionnaire was completed by 478 patients and the post-questionnaire was completed by 372. Seventy-seven percent of respondents knew their ideal blood pressure and their engagement with blood pressure management increased significantly (p=0.0024) after completing the protocol. Additionally, 85% of respondents said that they had a positive experience doing SMBP. Open-ended responses revealed insight regarding why patients chose to do SMBP and factors patients appreciated about SMBP.</p><p><strong>Discussion: </strong>When trained properly and supported, community health center patients are capable of and motivated to perform accurate SMBP. Our study provides evidence that health center patients can follow detailed SMBP protocols and monitor their own blood pressure from the safety of their homes, which is critical to their care continuum, particularly in days of a pandemic.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"14 ","pages":"19-29"},"PeriodicalIF":2.2,"publicationDate":"2021-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/a2/ibpc-14-19.PMC7886240.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25381466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Evidence of Nonadherence in Cases of Pseudoresistant Hypertension. 假性顽固性高血压病例的不依从证据。
IF 2.2
Integrated Blood Pressure Control Pub Date : 2021-02-11 eCollection Date: 2021-01-01 DOI: 10.2147/IBPC.S264057
João Marcos de Menezes Zanatta, Luciana Neves Cosenso-Martin, Valquíria da Silva Lopes, Jéssica Rodrigues Roma Uyemura, Aleandra Marton Polegati Santos, Manoel Ildefonso Paz Landim, Juan Carlos Yugar-Toledo, José Fernando Vilela-Martin
{"title":"Evidence of Nonadherence in Cases of Pseudoresistant Hypertension.","authors":"João Marcos de Menezes Zanatta, Luciana Neves Cosenso-Martin, Valquíria da Silva Lopes, Jéssica Rodrigues Roma Uyemura, Aleandra Marton Polegati Santos, Manoel Ildefonso Paz Landim, Juan Carlos Yugar-Toledo, José Fernando Vilela-Martin","doi":"10.2147/IBPC.S264057","DOIUrl":"10.2147/IBPC.S264057","url":null,"abstract":"<p><p>Resistant hypertension (RH) is characterized by the use of three or more antihypertensive drugs without reaching the goal of controlling blood pressure (BP). For a definitive diagnosis of RH, it is necessary to exclude causes of pseudoresistance, including the white-coat effect, errors in BP measurement, secondary hypertension, therapeutic inertia, and poor adherence to lifestyle changes and pharmacological treatment. Herein, we report the history of a patient with long-standing uncontrolled BP, even when using seven antihypertensive drugs. Causes of secondary hypertension that justified the high BP levels were investigated, in addition to the other causes of pseudo-RH. In view of the difficult-to-control BP situation, it was decided to hospitalize the patient for better investigation. After 5 days, he had BP control with practically the same medications previously used. Finally, all factors related to the presence of pseudo-RH are discussed, especially poor adherence to treatment. Poor adherence to antihypertensive treatment is common in daily medical practice, and its investigation is of fundamental importance for better management of BP.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"14 ","pages":"9-17"},"PeriodicalIF":2.2,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/b1/ibpc-14-9.PMC7887157.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25381465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Blood Pressure Control with Reference to Intensive Blood Pressure Targets Among Hypertension Patients on Chronic Follow-Up at Dessie Referral Hospital, Northeast Ethiopia. 埃塞俄比亚东北部Dessie转诊医院高血压患者慢性随访中强化血压指标的血压控制
IF 2.2
Integrated Blood Pressure Control Pub Date : 2021-01-22 eCollection Date: 2021-01-01 DOI: 10.2147/IBPC.S268186
Kassahun Bogale, Assasu Aderaw
{"title":"Blood Pressure Control with Reference to Intensive Blood Pressure Targets Among Hypertension Patients on Chronic Follow-Up at Dessie Referral Hospital, Northeast Ethiopia.","authors":"Kassahun Bogale,&nbsp;Assasu Aderaw","doi":"10.2147/IBPC.S268186","DOIUrl":"https://doi.org/10.2147/IBPC.S268186","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a risk factor for heart, brain, kidney, and other diseases. It is also the major cause of premature death. Thus, it is important to prevent, treat, and control hypertension and to reduce the risk of cardiovascular disease.</p><p><strong>Objective: </strong>To determine the level of blood pressure control and associated factors based on the new intensive blood pressure goals (<130/80 mmHg).</p><p><strong>Methods: </strong>A cross-sectional study design was used to assess the level of blood pressure control and associated factors from February 15 to April 15, 2019. Two hundred and sixteen patients were selected through a systematic sampling technique.</p><p><strong>Results: </strong>From 203 hypertension patients incorporated in the study, 102 (50.2%) were females. The mean age of patients documented during the last date of follow-up was 55.2 (SD=±14.47). About 51.2% of patients were less than 5 years from the day of diagnosis of hypertension. The majority of the study participants (111, 54.7%) were using two antihypertensives. The most common anti-hypertensive medication was hydrochlorothiazide (HCT), at 25 (12.3%). The most common combination drug therapy used was the combination of HCT and calcium channel blockers, at 62 (30.5%). Heart failure (22, 20.8%), stroke (18, 16.98%), and dyslipidemia (17, 16.04%) were the top three comorbidities. Based on the new intensive targets of blood pressure control (<130/80 mmHg), the blood pressure was controlled for only 25 (12%) patients.</p><p><strong>Conclusion: </strong>The level of blood pressure control for hypertensive patients on chronic follow-up at Dessie Referral Hospital was very poor.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"14 ","pages":"1-7"},"PeriodicalIF":2.2,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/7c/ibpc-14-1.PMC7837537.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25314492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ambulatory Blood Pressure Profiles and Correlation with Cardiovascular Risk Factors in a Sample of 390 University Employees in Tanzania. 坦桑尼亚390名大学员工动态血压特征及其与心血管危险因素的相关性
IF 2.2
Integrated Blood Pressure Control Pub Date : 2020-12-23 eCollection Date: 2020-01-01 DOI: 10.2147/IBPC.S280763
Godfrey Chuwa, Pilly Chillo
{"title":"Ambulatory Blood Pressure Profiles and Correlation with Cardiovascular Risk Factors in a Sample of 390 University Employees in Tanzania.","authors":"Godfrey Chuwa,&nbsp;Pilly Chillo","doi":"10.2147/IBPC.S280763","DOIUrl":"https://doi.org/10.2147/IBPC.S280763","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a major risk factor for cardiovascular morbidity and mortality. Increasingly, evidence suggests that 24-hour ambulatory blood pressure (BP) monitoring (ABPM) is more accurate than clinic BP in predicting cardiovascular risk. However, this association has not been widely studied in subSaharan Africa, especially in Tanzania.</p><p><strong>Aim: </strong>To explore the relationship between 24-hour ABPM profiles and cardiovascular risk factors in comparison with clinic BP among Muhimbili University of Health and Allied Sciences (MUHAS) employees.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted from October 2018 to February 2019. Socio-demographic and cardiovascular risk information was gathered. We used an automated ABPM device to record 24-hour ambulatory BP. Correlation between BP profiles and cardiovascular risk factors was done using Pearson's correlation coefficient, and independent factors for hypertension were determined using logistic regression analysis. <i>P</i>-value of <0.05 was considered statistically significant.</p><p><strong>Results: </strong>In total, 390 employees participated. Their mean age was 40.5 ± 8.9 years, and 53.6% were men. The mean office systolic and diastolic BP were 126±12 mmHg and 78±13 mmHg, respectively, while the corresponding values for mean 24-hour ABPM were 122±14 and 75±10 mmHg. The prevalence of hypertension was 23.1%. The prevalence of white coat hypertension was 16.2%, while masked hypertension and nocturnal non-dipping were present in 11.5 and 66.7%, respectively. Overall, the mean 24-hour systolic BP showed the strongest correlations with cardiovascular risk factors while mean office systolic BP showed least. Independent associated factors of hypertension were male gender, age ≥40 years, family history of hypertension, central obesity, raised cholesterol and uric acid levels, all p<0.01.</p><p><strong>Conclusion: </strong>Compared to office BP, ABPM measurements had stronger correlations with cardiovascular risk factors in this population, and therefore likely to reflect true BP. ABPM has revealed high proportion of masked, white coat and nocturnal non-dipping, supporting use of ABPM to detect these clinically important BP profiles.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"13 ","pages":"197-208"},"PeriodicalIF":2.2,"publicationDate":"2020-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/d3/ibpc-13-197.PMC7767712.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38766337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peri-Procedural Blood Pressure Changes and Their Relationship with MACE in Patients Undergoing Percutaneous Coronary Intervention: A Cross-Sectional Study. 经皮冠状动脉介入治疗患者术中血压变化及其与MACE的关系:一项横断面研究。
IF 2.2
Integrated Blood Pressure Control Pub Date : 2020-12-10 eCollection Date: 2020-01-01 DOI: 10.2147/IBPC.S268848
Susan Labib, Hussein Heshmat Kassem, Hossam Kandil
{"title":"Peri-Procedural Blood Pressure Changes and Their Relationship with MACE in Patients Undergoing Percutaneous Coronary Intervention: A Cross-Sectional Study.","authors":"Susan Labib,&nbsp;Hussein Heshmat Kassem,&nbsp;Hossam Kandil","doi":"10.2147/IBPC.S268848","DOIUrl":"https://doi.org/10.2147/IBPC.S268848","url":null,"abstract":"<p><strong>Background: </strong>Peri-procedural blood-pressure (BP) changes were investigated and correlated to Major adverse cardiovascular events (MACE) as predictor of outcome for patients undergoing percutaneous coronary intervention (PCI); whether acute coronary syndrome (Unstable angina, or MI; STEMI or NSTEMI) or scheduled for elective PCI.</p><p><strong>Methods: </strong>Resting BP in the 204 recruited patients undergoing PCI throughout 2018 was measured thrice - in the ward before transferring to the cardiac catheterization lab (cath lab), in the cath lab, and after transfer to the recovery room. Patients were categorized based on their systolic and diastolic BP peri-procedural difference as systolic (SBP): with a large difference (>20 mmHg, n=47), with a small difference (≤20 mmHg, n=157) (shock patients excluded); diastolic (DBP): with a large difference (>10 mmHg, n=65), and with a small difference (≤10 mmHg, n=139). The primary end-points were MACE including all-cause mortality, non-fatal myocardial infarction, and stroke during the hospital stay. The Mann-Whitney U and Chi-square tests were used to analyze the data accordingly (p<0.005).</p><p><strong>Results: </strong>Within the category of MACE, cardiac mortality was the only adverse cardiac event encountered in the study sample. Cardiac mortality was significantly higher in both the large SBP-difference group versus the other group (10.6% vs 0.6%, p=0.003) and the large DBP-difference group versus the small-difference group (7.7% vs 0.7%, p=0.013).</p><p><strong>Conclusion: </strong>Peri-procedural systolic and diastolic BP differences, greater than 20 mmHg and 10 mmHg, respectively, correlated with MACE in all patients undergoing PCI.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"13 ","pages":"187-195"},"PeriodicalIF":2.2,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/IBPC.S268848","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38736215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Anthropometric Indexes for Predicting High Blood Pressure in Vietnamese Adults: A Cross-Sectional Study. 预测越南成人高血压的人体测量指标:一项横断面研究。
IF 2.2
Integrated Blood Pressure Control Pub Date : 2020-12-01 eCollection Date: 2020-01-01 DOI: 10.2147/IBPC.S281996
Quan Nguyen Minh, Minh Hoang Nguyen Vo
{"title":"Anthropometric Indexes for Predicting High Blood Pressure in Vietnamese Adults: A Cross-Sectional Study.","authors":"Quan Nguyen Minh,&nbsp;Minh Hoang Nguyen Vo","doi":"10.2147/IBPC.S281996","DOIUrl":"https://doi.org/10.2147/IBPC.S281996","url":null,"abstract":"<p><strong>Background: </strong>The rate of hypertension and obesity is increasing in Vietnamese society. This study aimed to focus on assessing the relationship between anthropometric indexes (body mass index (BMI), waist-to-height ratio (WHtR), waist-to-hip ratio (WHR)) and high blood pressure to determine which is the best predictor for high blood pressure among adults over 18 years in Vietnam.</p><p><strong>Methods: </strong>A cross-sectional study of 1636 people was conducted. People who were over 18 years old, healthy or had hyperlipidemia and on the treatment were recruited. Patients with cancer, heart disease, diabetes, kidney disease, and hypertension were excluded. Information on demographics, smoking and drinking habits, weight, height, waist circumference, and blood pressure was collected. Areas under receiver operating characteristic curves (AUCs) were examined to determine the predictability of anthropometric indicators for high blood pressure in men and women. Logistic regression analysis, stratified by gender, was performed to examine the association between anthropometric indexes and high blood pressure.</p><p><strong>Results: </strong>In this study, the percentage of people with high blood pressure was 10.51%. The AUC for the WHtR was significantly greater than for the BMI for both genders. Logistic regression demonstrated that only WHtR had a significant positive association with high blood pressure among women. The optimal WHtR cut-off value for predicting high blood pressure in men and women were 0.47 and 0.50, respectively.</p><p><strong>Conclusion: </strong>Among the indicators analyzed in this study, WHtR was the best for the predicting of the presence of high blood pressure, in both men and women. However, WHtR could only explain the changes of high blood pressure in women.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"13 ","pages":"181-186"},"PeriodicalIF":2.2,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/2e/ibpc-13-181.PMC7718968.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38688461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Prevalence of Hypertension and Its Associated Factors Among Gimbi Town Residents, Ethiopia: A Community-Based Cross-Sectional Study. 埃塞俄比亚金比镇居民的高血压患病率及其相关因素:一项基于社区的横断面研究。
IF 1.5
Integrated Blood Pressure Control Pub Date : 2020-11-26 eCollection Date: 2020-01-01 DOI: 10.2147/IBPC.S277582
Birhanu Yadecha, Firew Tekle, Getahun Fetensa, Ashenafi Habte, Bisrat Zeleke
{"title":"Prevalence of Hypertension and Its Associated Factors Among Gimbi Town Residents, Ethiopia: A Community-Based Cross-Sectional Study.","authors":"Birhanu Yadecha, Firew Tekle, Getahun Fetensa, Ashenafi Habte, Bisrat Zeleke","doi":"10.2147/IBPC.S277582","DOIUrl":"10.2147/IBPC.S277582","url":null,"abstract":"<p><strong>Background: </strong>Globally, sixty-two percent of cerebrovascular disease and forty-nine percent of ischemic heart disease are attributable to increased blood pressure. Half of the patients with stroke and heart disease were due to hypertension.</p><p><strong>Objective: </strong>This study aimed to identify prevalence of hypertension and its associated factors in Gimbi town, Ethiopia.</p><p><strong>Methods: </strong>We conducted a community-based cross-sectional study from May to June 2017 on 471 participants in Gimbi town, western Ethiopia. A systematic sampling method was used to recruit study participants. Data collectors used structured questionnaires to gather data through face to face interview. The standardized procedure followed to measure blood pressure and anthropometric measurements by trained extension health workers. We entered data into Epi-data and exported to SPSS version 20.00 for analysis. Variables having a P-value less than or equal to 0.05 were declared as statistically significant in multivariable analysis.</p><p><strong>Results: </strong>Four hundred seventy-one participants were included with a response rate of 98.85%, and 248 (52.6%) were female. The prevalence of isolated systolic and diastolic hypertension was 9.55% and 9.3%, respectively. Of 157 (33.5%) hypertensive participants, 117 (24.8%) were newly diagnosed. Age 35-55 [AOR: 2.335 95% CI (1.360-4.009)], ≥55 [(AOR: 3.566 95% CI (1.288-9.876))], occupation, government employee [(AOR: 3.072 95% CI (1.458-6.474))], merchants [(AOR: 3.177 95% CI (1.290-7.824))], ever alcohol drinker [(AOR: 2.333 95% CI (1.320-4.122))], and family history of hypertension [(AOR: 6.642 95% CI (4.068-10.843))] were found to be predictor variables for hypertension.</p><p><strong>Conclusion: </strong>The findings of this study indicated a hidden high prevalence of hypertension indicating the need for stakeholders' collaboration to design and implement a mobile blood pressure screening programs at the community level.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"13 ","pages":"171-179"},"PeriodicalIF":1.5,"publicationDate":"2020-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/87/ibpc-13-171.PMC7705951.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38673167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Matrix Metalloproteinases and Hypertension-Mediated Organ Damage: Current Insights. 基质金属蛋白酶和高血压介导的器官损伤:当前的见解。
IF 2.2
Integrated Blood Pressure Control Pub Date : 2020-11-02 eCollection Date: 2020-01-01 DOI: 10.2147/IBPC.S223341
Valeria Bisogni, Alberto Cerasari, Giacomo Pucci, Gaetano Vaudo
{"title":"Matrix Metalloproteinases and Hypertension-Mediated Organ Damage: Current Insights.","authors":"Valeria Bisogni,&nbsp;Alberto Cerasari,&nbsp;Giacomo Pucci,&nbsp;Gaetano Vaudo","doi":"10.2147/IBPC.S223341","DOIUrl":"https://doi.org/10.2147/IBPC.S223341","url":null,"abstract":"<p><p>Matrix metalloproteinases (MMPs) are important extracellular enzymes involved in many physiological and pathological processes. Changes in the activity and concentration of specific MMPs, as well as the unbalance with their inhibitors (tissue inhibitors of metalloproteinases - TIMPs), have been described as a part of the pathogenic cascade promoted by arterial hypertension. MMPs are able to degrade various protein substrates in the extracellular matrix, to influence endothelial cells function, vascular smooth muscle cells migration, proliferation and contraction, and to stimulate cardiomyocytes changes. All these processes can be activated by chronically elevated blood pressure values. Animal and human studies demonstrated the key function of MMPs in the pathogenesis of hypertension-mediated vascular, cardiac, and renal damage, besides age and blood pressure values. Thus, the role of MMPs as biomarkers of hypertension-mediated organ damage and potential pharmacological treatment targets to prevent further cardiovascular and renal complications in hypertensive population is increasingly supported. In this review, we aimed to describe the main scientific evidence about the behavior of MMPs in the development of vascular, cardiac, and renal damage in hypertensive patients.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"13 ","pages":"157-169"},"PeriodicalIF":2.2,"publicationDate":"2020-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/IBPC.S223341","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38590921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Adherence to Lifestyle Modifications and Associated Factors Among Adult Hypertensive Patients Attending Chronic Follow-Up Units of Dessie Referral Hospital, North East Ethiopia, 2020. 埃塞俄比亚东北部Dessie转诊医院慢性随访单元成年高血压患者生活方式改变依从性及相关因素
IF 2.2
Integrated Blood Pressure Control Pub Date : 2020-10-23 eCollection Date: 2020-01-01 DOI: 10.2147/IBPC.S275575
Atsedemariam Andualem, Habtam Gelaye, Yitayish Damtie
{"title":"Adherence to Lifestyle Modifications and Associated Factors Among Adult Hypertensive Patients Attending Chronic Follow-Up Units of Dessie Referral Hospital, North East Ethiopia, 2020.","authors":"Atsedemariam Andualem,&nbsp;Habtam Gelaye,&nbsp;Yitayish Damtie","doi":"10.2147/IBPC.S275575","DOIUrl":"https://doi.org/10.2147/IBPC.S275575","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a major health problem throughout the world which affects over one billion people due to severe complications and inadequate control. Even though lifestyle modification is one of the most effective ways to prevent and control hypertension, only little emphasis has been given for it compared with treating hypertension with medication. Therefore, the aim of this study was to assess adherence to lifestyle modifications and associated factors among hypertensive patients attending Dessie referral hospital.</p><p><strong>Materials and methods: </strong>Institutional-based cross-sectional study design was conducted among 301 hypertensive patients during May and June, 2020. The study participants were selected with a convenient sampling technique due to the COVID-19 pandemic. Data were collected using pre-tested and structured face to face interviewer-administered questionnaire and checked, cleaned and entered into Epi data version 4.4 and exported to SPSS version 25.0 software for analysis. The associations between independent variables and dependent variable were analyzed using binary logistic regression models.</p><p><strong>Results: </strong>A total of 301 respondents participated in the study yielding a response of 100%. The overall adherence in this study was only 23.6%. Independent predictors of adherence to lifestyle modifications were divorced (AOR=0.35; 95% CI (0.13-0.94)) and widowed (AOR=0.27; 95% CI (0.10-0.75)), secondary school education (AOR=4.85; 95% CI (1.54-15.22)), no regular income (AOR=0.22; 95% CI (0.08-0.65)) or monthly income of ≥3000 ETB (AOR=5.58; 95% CI (2.46-12.66)), having co-morbidities (AOR=2.37; CI (1.23-4.57)), good knowledge about the disease (AOR=1.83; CI (0.92-3.65)) and good self-efficacy (AOR=3.64; CI (1.75-7.55)).</p><p><strong>Conclusion and recommendations: </strong>The overall adherence to recommended lifestyle modifications was very low. The independent predictors were marital status, educational level, monthly income, having co-morbidities, knowledge and self-efficacy. Therefore, multifaceted and collaborative implementation of strategies about lifestyle modifications for hypertension prevention and control are needed to address barriers at the patient, provider, system and community levels.</p>","PeriodicalId":45299,"journal":{"name":"Integrated Blood Pressure Control","volume":"13 ","pages":"145-156"},"PeriodicalIF":2.2,"publicationDate":"2020-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/IBPC.S275575","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38544178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
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