Allergy & Rhinology最新文献_第8页

Radiologic Contrast Media Desensitization for Delayed Cardiac Catheterization. 放射性造影剂脱敏治疗延迟性心脏导管插入术。

IF 2.2

Allergy & Rhinology Pub Date : 2019-12-16 eCollection Date: 2019-01-01 DOI: 10.1177/2152656719892844

Neha Sanan, Marija Rowane, Robert Hostoffer

引用次数: 2

No Bull: A Case of Alpha-Gal Syndrome Associated With Buffalo Meat Sensitivity. 没有公牛:一个与水牛肉敏感相关的α - gal综合征病例。

IF 2.2

Allergy & Rhinology Pub Date : 2019-12-08 eCollection Date: 2019-01-01 DOI: 10.1177/2152656719893366

Marija Rowane, Reimus Valencia, Benjamin Stewart-Bates, Jason Casselman, Robert Hostoffer

{"title":"No Bull: A Case of Alpha-Gal Syndrome Associated With Buffalo Meat Sensitivity.","authors":"Marija Rowane, Reimus Valencia, Benjamin Stewart-Bates, Jason Casselman, Robert Hostoffer","doi":"10.1177/2152656719893366","DOIUrl":"https://doi.org/10.1177/2152656719893366","url":null,"abstract":"Introduction: Alpha (⍺)-gal syndrome (AGS) is an immunoglobulin E (IgE) antibody response against the glycoprotein carbohydrate galactose-⍺-1,3-galactose-β-1-(3)4-N-acetylglucosamine-R (Gal⍺-1,3Galβ1-(3)4GlcNAc-R or ⍺-gal) that is present in Ixodida (tick) saliva and noncatarrhine mammals as well as cetuximab, antivenom, and the zoster vaccine. The most frequently observed anaphylactic reactions in AGS are observed after beef, pork, lamb, and deer meat consumption. We present the first case of anaphylaxis to buffalo meat.Case report: A 55-year-old man presented with a history of recurrent urticaria that only developed approximately 7 hours after buffalo consumption. The patient denied history of Ixodidae bites but admitted to frequent hiking outdoors. Anti-⍺-1,3-gal IgE was positive (30.80 kU/L). The patient was advised to strictly avoid red meat.Discussion: The prevalence of AGS has been increased in all continents in the past decade, and several Ixodidae species have been associated with this hypersensitivity. The list of IgE-mediated reactions to various types of meat has expanded to kangaroo, whale, seal, and crocodile, although these have not been associated with AGS. van Nunen only cautioned against consumption of exotic meats, such as buffalo, but no published case report describes AGS associated with anaphylaxis to this type of meat.Conclusion: AGS is a mammalian meat allergy that has been increasingly prevalent worldwide, especially in Ixodidae endemic regions of Australia and the United States. Multiple AGS case reports published in the past decade demonstrate rapidly increasing understanding of underlying mechanisms provoking ongoing sensitization to help devise management strategies and dietary information. We offer the first case report of delayed anaphylaxis to buffalo meat.","PeriodicalId":45192,"journal":{"name":"Allergy & Rhinology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2019-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2152656719893366","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37459912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Malignant Chondroid Syringoma With Nose and Paranasal Sinus Extension: A Case Report. 恶性软骨样淋巴瘤伴鼻及副鼻窦延伸1例。

IF 2.2

Allergy & Rhinology Pub Date : 2019-12-03 eCollection Date: 2019-01-01 DOI: 10.1177/2152656719893367

Raghul Sekar, Raja Kalaiarasi, Sivaraman Ganesan, Arun Alexander, Sunil K Saxena

引用次数: 5

Familial Success in Allergen Desensitization. 过敏原脱敏的家族成功

IF 2.3

Allergy & Rhinology Pub Date : 2019-11-19 eCollection Date: 2019-01-01 DOI: 10.1177/2152656719890315

Marija Rowane, Ryan Shilian, Devi K Jhaveri, Haig H Tcheurekdjian, Theordore H Sher, Robert Hostoffer

{"title":"Familial Success in Allergen Desensitization.","authors":"Marija Rowane, Ryan Shilian, Devi K Jhaveri, Haig H Tcheurekdjian, Theordore H Sher, Robert Hostoffer","doi":"10.1177/2152656719890315","DOIUrl":"10.1177/2152656719890315","url":null,"abstract":"Introduction: Allergic rhinitis (AR) is a widely prevalent immunoglobulin E-mediated inflammatory nasal condition resulting from reexposure to an allergen in a sensitized individual. The genetic associations behind AR and other allergic conditions have been studied. However, familial success with AR therapies, specifically allergen desensitization through subcutaneous immunotherapy (SCIT), has never been reported in the literature. Pharmocogenetics has been gradually applied to link heritable genetic variants with drug responses, such as intergenic region variants APOBEC3B and APOBEC3C and β2-adrenergic receptor and glycoprotein ADAM33 polymorphisms as predictive biomarkers for biologic treatment response in asthma. We provide the first reported survey of familial success with SCIT.Methods: We administered a month-long, institutional review board-approved (20190493) questionnaire to 200 adult patients receiving SCIT in a suburban allergy/immunology practice. The anonymous survey inquired about demographics, target allergens for their SCIT, current symptom improvement on SCIT, and family history of allergies and SCIT management.Results: Twenty-six percent (52 of 200, 26%) SCIT patients reported familial success with the same allergy treatment modality. AR diagnosis and symptom improvement from SCIT was similar among previous/same (18 of 52, 38%; 26 of 52, 54%) and subsequent (10 of 52, 21%; 19 of 52, 40%) generations of family members. A combination of seasonal and perennial allergies was most prevalent (81%) among this population.Conclusion: In a subpopulation of SCIT patients, there appears to be a familial success rate with this allergen desensitization treatment. This is the first reported pharmocogenetic evidence of assessing hereditary influence on effective AR therapy. Understanding pharmacogenetic associations involved with SCIT may improve allergists' recommendations for this treatment option.","PeriodicalId":45192,"journal":{"name":"Allergy & Rhinology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2019-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42453965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic Endonasal Repair of Spontaneous Cerebrospinal Fluid Leaks Using Multilayer Composite Graft and Vascularized Pedicled Nasoseptal Flap Technique 经鼻内窥镜下应用多层复合移植物和带血管蒂鼻中隔瓣技术修复自发性脑脊液泄漏

IF 2.2

Allergy & Rhinology Pub Date : 2019-11-01 DOI: 10.1177/2152656719888622

Natalie Kim-Orden, Jasper Shen, Maya Or, Kevin Hur, G. Zada, B. Wrobel

{"title":"Endoscopic Endonasal Repair of Spontaneous Cerebrospinal Fluid Leaks Using Multilayer Composite Graft and Vascularized Pedicled Nasoseptal Flap Technique","authors":"Natalie Kim-Orden, Jasper Shen, Maya Or, Kevin Hur, G. Zada, B. Wrobel","doi":"10.1177/2152656719888622","DOIUrl":"https://doi.org/10.1177/2152656719888622","url":null,"abstract":"Background Endoscopic repair of cerebrospinal fluid (CSF) fistulas is a fundamental practice in anterior skull base surgery due to high success rates and low morbidity profile. However, spontaneous CSF (sCSF) leaks have the highest recurrence rate compared to other etiologies. The most effective management is undetermined due to variations in graft materials and limited evidence. Objective We present the largest study of a standardized endoscopic repair technique for sCSF leaks. Methods Single-institution retrospective review of patients who underwent endoscopic sCSF leak repair between October 2011 and January 2018. All patients underwent repair using a temporary lumbar drain, intrathecal fluorescein, and multilayer reconstruction using bilayered fascia lata autograft and vascularized nasoseptal flap. Results Twenty patients (100% female, mean age: 53.2 years) with 25 separate sCSF leak sites were included. Obesity was present in 15 of 20 patients (mean body mass index [BMI] = 35.3). No patients had previous sinus surgery. Locations of skull base defects included: cribriform plate (44%), ethmoid (32%), lateral sphenoid (12%), and planum sphenoidale (12%). The mean follow-up was 22.8 months and 92% of the leak sites (23/25) were successfully repaired primarily. There were no neurological complications or cases of meningitis. Two patients (mean BMI = 52) with persistent postoperative CSF leaks and elevated intracranial pressure were successfully managed with ventriculoperitoneal shunt placement. BMI was associated with likelihood of repair failure (P = .003). Conclusions At our institution, endoscopic repair of sCSF leaks using a composite autograft of fascia and a nasoseptal flap demonstrates high success rates. Elevated BMI was a statistically significant risk factor for revision.","PeriodicalId":45192,"journal":{"name":"Allergy & Rhinology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2152656719888622","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65514839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

IF 2.2

Allergy & Rhinology Pub Date : 2019-07-01 DOI: 10.1177/2152656719860820

F. Sadeghi, Mohammad Shirkhoda

{"title":"Allergy-Related Diseases and Risk of Breast Cancer: The Role of Skewed Immune System on This Association","authors":"F. Sadeghi, Mohammad Shirkhoda","doi":"10.1177/2152656719860820","DOIUrl":"https://doi.org/10.1177/2152656719860820","url":null,"abstract":"Background The role of allergy in breast cancer (BC) development remains inconclusive. A comprehensive review article is required to present and discuss all findings on this topic and to clarify the association between allergic disorders and the risk of BC. Objective We aimed to explain the association between atopy, different types of allergic disorders, and the risk of BC. Moreover, we explored the immunological mechanism behind this association. Methods We electronically reviewed publications in PubMed from 1979 to 2018 relating to atopy, allergy, asthma, atopic dermatitis, allergic rhinitis, food allergy, drug allergy, immunoglobulin E (IgE) or prick test, and BC. Results Most of the identified studies demonstrated nonsignificant results. However, the pattern of the results indicated an increased risk of BC in individuals with a history of allergies. The majority of studies reported higher prevalence of atopic dermatitis and allergic rhinitis among individuals with BC compared to the control groups. Similarity, most of the studies revealed an increased risk of BC among people with a positive history of atopic using IgE specific or prick test. However, a null association was reported in most of the asthmatic studies, and controversial results were detected in the individuals with history of food and drug allergies. Conclusion The majority of findings were not statistically significant. Moreover, bias and other methodological problems are the major issues, which make it challenging to compare the findings of different studies and reach a strong conclusive result. However, the pattern of the results from most studies indicated that allergic diseases might be associated with an increased risk of BC. Skewed immune system toward T-helper 2 might have an important role in this association.","PeriodicalId":45192,"journal":{"name":"Allergy & Rhinology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2152656719860820","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47213411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Localized Sinonasal Amyloidosis 局限性鼻窦淀粉样变

IF 2.2

Allergy & Rhinology Pub Date : 2019-07-01 DOI: 10.1177/2152656719860821

Nur Wahidah Wahid, T. Abed, S. Meghji, J. Gilbertson, M. Barnes

引用次数: 4

Role of Food Allergy Education: Measuring Teacher Knowledge, Attitudes, and Beliefs. 食物过敏教育的作用:测量教师的知识、态度和信念。

IF 2.2

Allergy & Rhinology Pub Date : 2019-06-20 eCollection Date: 2019-01-01 DOI: 10.1177/2152656719856324

Nicole Canon, Maya Gharfeh, Danielle Guffey, Sara Anvari, Carla M Davis

{"title":"Role of Food Allergy Education: Measuring Teacher Knowledge, Attitudes, and Beliefs.","authors":"Nicole Canon, Maya Gharfeh, Danielle Guffey, Sara Anvari, Carla M Davis","doi":"10.1177/2152656719856324","DOIUrl":"https://doi.org/10.1177/2152656719856324","url":null,"abstract":"Introduction Almost 6 million children suffer from food allergies with roughly 2 affected per classroom. Deficiencies in knowledge and discrepancies in attitudes within school staff when addressing food allergies are associated with barriers to care. In this study, school teacher knowledge, beliefs, and attitudes were measured before and after a food allergy educational session. Methods Three hundred seventy-five personnel of similar age, socioeconomic status, ethnicity, and educational level completed the Chicago Food Allergy Research survey before and after a 1-hour educational session in 6 private schools in Houston randomly assigned into an intervention (n = 4) and control group (n = 2). Responses were measured using frequencies and percentages. The group score differences and survey question comparisons were evaluated with a linear mixed-effects model. Results Posttest, the intervention group had knowledge scores 19.58% points higher than control (95% confidence interval = 16.62–22.53; P < .001) with no differences pretest. Odds of agreeing that injectable epinephrine is important was higher in the intervention schools posteducation. Within the intervention group, personnel were more likely to agree to injectable epinephrine use for children posteducation. Conclusion A 1-hour educational session improved knowledge and attitudes in personnel in the intervention schools. Given the growing prevalence of food allergy, the emphasis on food allergy education is crucial to allow for familiarization of the condition, early recognition of anaphylaxis, and promotion of injectable epinephrine use.","PeriodicalId":45192,"journal":{"name":"Allergy & Rhinology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2152656719856324","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37377870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Intraseptal Mucocele as a Long-term Complication of Revision Septorhinoplasty: A Case Report and Review of a Rare Entity. 鼻中隔翻修成形术的长期并发症:一例罕见病例报告及回顾。

IF 2.2

Allergy & Rhinology Pub Date : 2019-05-29 eCollection Date: 2019-01-01 DOI: 10.1177/2152656719845325

Jordan W Rawl, Nicholas A Rossi, Mohamad R Chaaban, Paul Brindley

引用次数: 3

Spontaneous Regression of Swollen Submandibular Glands in IgG4-Related Disease. igg4相关疾病中颌下腺肿胀的自发消退

IF 2.2

Allergy & Rhinology Pub Date : 2019-05-02 eCollection Date: 2019-01-01 DOI: 10.1177/2152656718816738

Masanobu Suzuki, Yuji Nakamaru, Dai Takagi, Aya Honma, Takayoshi Suzuki, Emi Takakuwa, Shinya Morita, Sarah Vreugde, Akihiro Homma

{"title":"Spontaneous Regression of Swollen Submandibular Glands in IgG4-Related Disease.","authors":"Masanobu Suzuki, Yuji Nakamaru, Dai Takagi, Aya Honma, Takayoshi Suzuki, Emi Takakuwa, Shinya Morita, Sarah Vreugde, Akihiro Homma","doi":"10.1177/2152656718816738","DOIUrl":"https://doi.org/10.1177/2152656718816738","url":null,"abstract":"Background: IgG4-related disease is a new clinical entity frequently associated with swelling of the submandibular glands (SMGs). The long-term outcome of SMG swelling without steroid therapy remains unknown.Objective: To examine whether swollen SMGs spontaneously regress without steroid therapy in the context of IgG4-related disease and to identify biomarkers that can predict the spontaneous regression of SMG swelling.Methods: The SMG volume of 49 patients diagnosed with IgG4-related disease was calculated by measuring the axial and coronal planes of computed tomography scans. The change in SMG volume over time was measured and examined by treatment regimen, clinical data, and serum complement level.Results: We found 28 of 49 (57%) IgG4-related disease patients to have swollen SMGs, with 15 of 20 (75%) of the swollen SMGs regressing without steroid therapy. The time required for the SMGs swelling to regress was significantly shorter in the steroid therapy group than in the no-steroid therapy group. Serum complement components at the initial visit were significantly lower in the regressed SMG group than in the nonregressed SMG group.Conclusion: We observed 75% of swollen SMGs spontaneously regressed in patients with IgG4-related disease. The time required for the swollen SMGs to regress was longer in patients without steroid therapy than in those with steroid therapy. Serum complement level could be used as a predictor for the spontaneous regression of swollen SMGs in patients with IgG4-related disease.","PeriodicalId":45192,"journal":{"name":"Allergy & Rhinology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2019-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2152656718816738","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39904805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2