Zdravstveno Varstvo最新文献_第10页

Screening Strategy Modification Based on Personalized Breast Cancer Risk Stratification and its Implementation in the National Guidelines - Pilot Study. 基于个体化乳腺癌风险分层的筛查策略修改及其在国家指南中的实施-试点研究。

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0027

Mateja Krajc, D Gareth Evans, Ana Blatnik, Katarina Lokar, Tina Žagar, Sonja Tomšič, Janez Žgajnar, Vesna Zadnik

{"title":"Screening Strategy Modification Based on Personalized Breast Cancer Risk Stratification and its Implementation in the National Guidelines - Pilot Study.","authors":"Mateja Krajc, D Gareth Evans, Ana Blatnik, Katarina Lokar, Tina Žagar, Sonja Tomšič, Janez Žgajnar, Vesna Zadnik","doi":"10.2478/sjph-2020-0027","DOIUrl":"https://doi.org/10.2478/sjph-2020-0027","url":null,"abstract":"Background: One of the most consistent models for estimating personalized breast cancer (BC) risk is the Tyrer-Cuzick algorithm that is incorporated into the International Breast Cancer Intervention Study (IBIS) software. Our main objective was to provide criteria for the classification of the Slovenian population, which has BC incidence below the European average, into risk groups, and to evaluate the integration of the criteria in Slovenian guidelines. Our main focus was on women age <50 with higher BC risk, since no organized BC screening is available for these women.Methods: Slovenian age-specific BC risks were incorporated into IBIS software and threshold values of risk categories were determined. Risk categories were assigned according to the individual's ten-year risk for women aged 40 and older, and lifetime risk for women between 20 and 39. To test the software, we compared screening strategies with the use vs. no use of IBIS.Results: Of the 197 women included in the study IBIS assigned 75.1% to the BC risk group, and the rest to the moderately increased risk. Without IBIS 80 women were offered mammographic and 33 ultrasound screening. In contrast, 28 instead of 80 would have been offered mammographic screening and there would have been no referrals for ultrasound if IBIS had been used.Conclusions: The Slovenian IBIS has been developed, tested and suggested for personalized breast cancer risk assessment. The implementation of the software with the consideration of Slovenian risk thresholds enables a more accurate and nationally unified assessment.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"211-218"},"PeriodicalIF":1.5,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/58/sjph-59-211.PMC7583429.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38649207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Expanded Newborn Screening Program in Slovenia using Tandem Mass Spectrometry and Confirmatory Next Generation Sequencing Genetic Testing. 斯洛文尼亚利用串联质谱法和确证性新一代测序基因测试扩大新生儿筛查计划。

IF 1.6 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0032

Barbka Repič Lampret, Žiga Iztok Remec, Ana Drole Torkar, Mojca Žerjav Tanšek, Andraz Šmon, Vanesa Koračin, Vanja Čuk, Daša Perko, Blanka Ulaga, Ana Marija Jelovšek, Maruša Debeljak, Jernej Kovač, Tadej Battelino, Urh Grošelj

{"title":"Expanded Newborn Screening Program in Slovenia using Tandem Mass Spectrometry and Confirmatory Next Generation Sequencing Genetic Testing.","authors":"Barbka Repič Lampret, Žiga Iztok Remec, Ana Drole Torkar, Mojca Žerjav Tanšek, Andraz Šmon, Vanesa Koračin, Vanja Čuk, Daša Perko, Blanka Ulaga, Ana Marija Jelovšek, Maruša Debeljak, Jernej Kovač, Tadej Battelino, Urh Grošelj","doi":"10.2478/sjph-2020-0032","DOIUrl":"10.2478/sjph-2020-0032","url":null,"abstract":"Introduction: In the last two decades, the introduction of tandem mass spectrometry in clinical laboratories has enabled simultaneous testing of numerous acylcarnitines and amino acids from dried blood spots for detecting many aminoacidopathies, organic acidurias and fatty acid oxidation disorders. The expanded newborn screening was introduced in Slovenia in September 2018. Seventeen metabolic diseases have been added to the pre-existing screening panel for congenital hypothyroidism and phenylketonuria, and the newborn screening program was substantially reorganized and upgraded.Methods: Tandem mass spectrometry was used for the screening of dried blood spot samples. Next-generation sequencing was introduced for confirmatory testing. Existing heterogeneous hospital information systems were connected to the same laboratory information system to allow barcode identification of samples, creating reports, and providing information necessary for interpreting the results.Results: In t he first y ear of t he expanded newborn screening a total of 15,064 samples w ere screened. Four patients were confirmed positive with additional testing.Conclusions: An expanded newborn screening program was successfully implemented with the first patients diagnosed before severe clinical consequences.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"256-263"},"PeriodicalIF":1.6,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2c/85/sjph-59-256.PMC7583424.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38649212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Increasing Scabies Incidence in Croatia: A Call for Coordinated Action Among Dermatologists, Physicians and Epidemiologists. 克罗地亚日益增加的疥疮发病率:呼吁皮肤科医生、内科医生和流行病学家采取协调行动。

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0033

Liborija Lugović-Mihić, Marija Delaš Aždajić, Sanja Kurečić Filipović, Iva Bukvić, Ivana Prkačin, Danijela Štimac Grbić, Mirjana Lana Kosanović Ličina

{"title":"An Increasing Scabies Incidence in Croatia: A Call for Coordinated Action Among Dermatologists, Physicians and Epidemiologists.","authors":"Liborija Lugović-Mihić, Marija Delaš Aždajić, Sanja Kurečić Filipović, Iva Bukvić, Ivana Prkačin, Danijela Štimac Grbić, Mirjana Lana Kosanović Ličina","doi":"10.2478/sjph-2020-0033","DOIUrl":"https://doi.org/10.2478/sjph-2020-0033","url":null,"abstract":"Introduction: The aim of our study was to examine the scabies incidence in the Croatian population and to analyse potential related factors.Methods: This mixed ecological study is based on a retrospective medical record review. National data from communicable disease reports was sourced and analysed for an 11-year period (2007-2017), with more focus on the period 2014-2017. Descriptive statistics were used to calculate trends. Differences between the groups were studied using Chi-square test and Kendall's tau (τ) correlation coefficient. Levels of significance were set at p<0.05 or p<0.01.Results: From 2007 to 2017, scabies infestation in Croatia increased by 6-fold, particularly affecting children and young adults (19 years or younger). In the period 2014-2017, border counties which are part of migration flows were the counties with the highest average scabies incidences. A linear trend of increase in the number of tourists, immigrants and scabies infestations was noted on the national level for the analysed period, although a significant association was not observed. Regarding outbreaks of scabies within institutions, more than 80% of outbreaks occurred in institutions for adults. In the capital, Zagreb, the crude incidence rate increased 3-fold between 2014 and 2017.Conclusions: The increased incidence of scabies, large disparities between counties, and prolonged outbreaks within families due to under-recognition and misdiagnoses points to a need for increased awareness among health practitioners. To the best of our knowledge, this is the first recent epidemiologic analysis on this topic, not only in Croatia but within the wider geographic region as well.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"264-272"},"PeriodicalIF":1.5,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/06/df/sjph-59-264.PMC7583432.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38553577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Measles Outbreak in a Roma Community in the Eastern Region of Slovakia, May to October 2018. 2018年5月至10月斯洛伐克东部地区罗姆人社区麻疹疫情

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0028

Henrieta Hudečková, Janka Stašková, Ján Mikas, Adriana Mečochová, Edita Staroňová, Alexandra Polčičová, Tibor Baška, Martin Novák, Nora Malinovská, Jana Zibolenová, Viera Švihrová, Elena Nováková, Mária Štefkovičová

{"title":"Measles Outbreak in a Roma Community in the Eastern Region of Slovakia, May to October 2018.","authors":"Henrieta Hudečková, Janka Stašková, Ján Mikas, Adriana Mečochová, Edita Staroňová, Alexandra Polčičová, Tibor Baška, Martin Novák, Nora Malinovská, Jana Zibolenová, Viera Švihrová, Elena Nováková, Mária Štefkovičová","doi":"10.2478/sjph-2020-0028","DOIUrl":"https://doi.org/10.2478/sjph-2020-0028","url":null,"abstract":"Background: Despite the effective National Immunization Programme of Slovakia, some population groups are incompletely vaccinated or unvaccinated. We aimed to describe the measles outbreak spread in Eastern Slovakia between May and October 2018, affecting the Roma communities in relation to the existing immunity gaps.Methods: We defined a group of persons living in socially closed communities with low vaccination coverage.Results: Of 439 measles cases (median age: 10 years), 264 (60.1%) were vaccinated, 137 (31.2%) received two doses and 127 (28.9%) one dose of measles vaccines, 155 (35.3%) were unvaccinated and 20 (4.6%) had an unknown vaccination status. Samples from 102 patients (with two-dose vaccination status) were additionally tested for antibodies against rubella and mumps. Of 102 cases, 68 (66.7%) cases had a positive IgM and 23 (22.5 %) IgG antibodies against measles. For rubella, only 20 (19.6%) cases had seropositive IgG levels, for mumps higher positivity was detected in 60 persons (58.8%). We could detect only a small percentage with positive serology results of rubella IgG antibodies across all age groups. We have assumed that rubella antibodies had to be produced following the vaccination. Their absence in the cases with two doses of MMR suggests that these vaccines could not have been administrated despite the fact that this data was included in the medical records. Sequential analysis of two samples showed measles genotype B3.Conclusion: This outbreak can outline the existence of a vulnerable group of the Roma. Low vaccinate coverage represents a serious public health threat.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"219-226"},"PeriodicalIF":1.5,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/64/0b/sjph-59-219.PMC7583425.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38649208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Barriers Affecting the Oral Health of People Diagnosed with Depression: A Systematic Review. 影响抑郁症患者口腔健康的障碍:系统综述。

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0034

Miloš Stepović, Dalibor Stajić, Zlata Rajković, Milena Maričić, Marija Sekulić

{"title":"Barriers Affecting the Oral Health of People Diagnosed with Depression: A Systematic Review.","authors":"Miloš Stepović, Dalibor Stajić, Zlata Rajković, Milena Maričić, Marija Sekulić","doi":"10.2478/sjph-2020-0034","DOIUrl":"https://doi.org/10.2478/sjph-2020-0034","url":null,"abstract":"Introduction: The problems of oral health of people diagnosed with depression are not adequately recognized, either in developed or developing countries. Social stigma, lack of self-interest, or even inadequate approaches of dental doctors towards the unique situation of this group of people this lead to excessive oral health problems.Methods: The bibliographic database PubMed/Medline, Google Scholar, and Whiley online library were searched using the following text and MeSH as separate key terms and in combination: depression and oral health/dental caries/periodontal disease/tooth loss/utilization of oral health services/and barriers. The content of documents was analysed using qualitative methodology.Results: Twenty-six original studies were included in the review. Level/severity of depression, medication and medical comorbidity are the most important medical barriers influencing the oral health of people diagnosed with depression. Dental fear and anxiety are mostly combined with low oral hygiene and bad oral health. Socioeconomic status, dental insurance, bad habits and education also have important roles in the oral health status of people diagnosed with depression.Conclusion: Including individuals with depression and oral health problems in national health programs, creating specific prevention programs, or subsidizing the cost of treatment are some of the recommendations suggested as solutions.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"273-280"},"PeriodicalIF":1.5,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4b/f0/sjph-59-273.PMC7583427.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38553578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Training Family Doctors and Primary Care Nurses in Evidence-based Prevention, Screening and Management of Cardiovascular Risks in Western Ukraine: A Longitudinal Study. 培训家庭医生和初级保健护士在乌克兰西部的循证预防、筛查和管理心血管风险:一项纵向研究。

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0029

Ivanna Shushman, Pavlo Kolesnyk, Yochai Schonmann, Michael Harris, Thomas Frese

{"title":"Training Family Doctors and Primary Care Nurses in Evidence-based Prevention, Screening and Management of Cardiovascular Risks in Western Ukraine: A Longitudinal Study.","authors":"Ivanna Shushman, Pavlo Kolesnyk, Yochai Schonmann, Michael Harris, Thomas Frese","doi":"10.2478/sjph-2020-0029","DOIUrl":"https://doi.org/10.2478/sjph-2020-0029","url":null,"abstract":"Introduction: The Ukrainian primary healthcare programme of preventive and screening recommendations has not been evidence-based. The traditional system of continuous medical education in Ukraine places participants in the role of passive listeners. This study explored the effects of an interactive training course on evidence-based prevention and screening of cardiovascular risks, on changes in Ukrainian family doctors' (FDs) and primary care nurses' (PCNs) knowledge and readiness to change practice over time.Methods: Three hundred and seven FDs and PCNs participated in the study. Changes in participants' knowledge were assessed with 20 multiple choice questions, and their readiness to change practice with a five-item questionnaire. These were administered before, immediately after, three and twelve months after training.Results: The mean pre-course knowledge score was 6.1 (SD 1.8) out of 20, increasing to 14.9 (SD 2.3) immediately afterwards (p<0.001). Three months later it was 10.2 (SD 3.2) and at one year it was 10.4 (SD 3.3), both of which were significantly higher than the pre-training level (p<0.005). The percentage of participants that were highly motivated to change their practice increased from 18.4% before the training to 62.3% immediately afterwards (p<0.001). Three months later, this fell to 40.4%. At 12 months it further reduced to 27.4%, but was still significantly higher than the baseline level (p<0.001).Conclusions: The interactive training was effective in increasing both participants' knowledge and their readiness to change their clinical practice. The impact of the training diminished over time, but was still evident a year later.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"227-235"},"PeriodicalIF":1.5,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/01/sjph-59-227.PMC7583428.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38649209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Changing Epidemiology of Presumptive Community-associated-methicillin-resistant Staphylococcus Aureus in Slovenia in 2014-2015 Compared To 2010. 与2010年相比，2014-2015年斯洛文尼亚推定社区相关耐甲氧西林金黄色葡萄球菌流行病学的变化

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0030

Urška Dermota, Irena Grmek Košnik, Sandra Janežič, Maja Rupnik

{"title":"Changing Epidemiology of Presumptive Community-associated-methicillin-resistant Staphylococcus Aureus in Slovenia in 2014-2015 Compared To 2010.","authors":"Urška Dermota, Irena Grmek Košnik, Sandra Janežič, Maja Rupnik","doi":"10.2478/sjph-2020-0030","DOIUrl":"https://doi.org/10.2478/sjph-2020-0030","url":null,"abstract":"Introduction: Although the distinction between the Community-Associated-Methicillin-Resistant Staphylococcus aureus (CA-MRSA) and Hospital-Associated-Methicillin-Resistant S. aureus (HA-MRSA) has blurred in recent years, the CA-MRSA is an important group because of its potential to cause fulminant and severe infections. Its importance has further increased with the emergence of Livestock-Associated-Methicillin-Resistant S. aureus (LA-MRSA).Methods: In the present study we analysed clonal distributions and virulence factors in presumptive CA-MRSA isolated from January 2014 to December 2015 and compared the results with our previous study from 2010. Phenotypic definition for presumptive CA-MRSA was based on resistance to cefoxitin and oxacillin and susceptibility to at least two of the following four antibiotics: ciprofloxacin, erythromycin, clindamycin and gentamicin.Results: In 2014 and 2015 altogether 304 MRSA isolates fulfilled our screening phenotypic definition, 45 isolates were cultivated from clinical specimens and 259 from screening specimens. Sequence types ST398, LA-MRSA and mecC MRSA increased significantly in 2015 compared to 2010 (p-value <0.05) and were spread over Slovenia.Conclusion: The clonal distribution of presumptive CA-MRSA has changed within the study period in Slovenia. In 2015 the most frequent clone among clinical and screening specimens was a pig-associated clone, ST398, but the number of confirmed ST398 infections remains low. While previously ST398 and mecC positive MRSA strains were geographically limited, they have spread throughout the country since 2010.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"236-244"},"PeriodicalIF":1.5,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/f1/sjph-59-236.PMC7583430.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38649210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Introducing the Early Trauma Inventory Self Report - Short Form and its Qualitative and Quantitative Validation for the Slovenian General Population. 介绍早期创伤清单自我报告-简短形式及其定性和定量验证斯洛文尼亚一般人群。

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-10-18 eCollection Date: 2020-12-01 DOI: 10.2478/sjph-2020-0031

Jelena Ristić-Ilić, Andrej Kastelic

{"title":"Introducing the Early Trauma Inventory Self Report - Short Form and its Qualitative and Quantitative Validation for the Slovenian General Population.","authors":"Jelena Ristić-Ilić, Andrej Kastelic","doi":"10.2478/sjph-2020-0031","DOIUrl":"https://doi.org/10.2478/sjph-2020-0031","url":null,"abstract":"Introduction: Traumatic experience in childhood or adolescence has a significant impact on the development of chronic mental and physical conditions in adulthood. Thus, it is very important for health professionals, especially primary care physicians to have an inventory in order to detect early trauma for planning appropriate treatment, such as the Early Trauma Inventory (ETI). The aim of this paper is to test the psychometric properties of the Slovenian translation of the short, self-rated version (ETISR-SF), and to further validate the instrument.Methods: The research was done in two parts - qualitative and quantitative. In the qualitative part, a questionnaire was translated and culturally adapted using the Delphi method. For the quantitative part, 51 patients with substance use disorders hospitalized at the Centre for the Treatment of Drug Addictions were recruited, along with 133 controls. The psychometric properties of the questionnaire were checked. Internal consistency was calculated using Cronbach's alpha, test-retest reliability was examined graphically using a Bland-Altman plot. Discriminant validity between groups was gauged using the independent samples t-test.Results: Consensus in the Delphi study was reached in the second round. Cronbach's alpha varied between 0.60 - 0.85. Of the four domains, physical abuse had the lowest Cronbach's alpha. The test-retest reliability is high for all domains, with correlation coefficients ranging from 0.82 to 0.96. The non-clinical sample differed significantly from the clinical sample.Conclusion: The Slovenian translation of ETISR-SF is a satisfactory instrument for the evaluation of trauma before the age of 18.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 4","pages":"245-255"},"PeriodicalIF":1.5,"publicationDate":"2020-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/d1/sjph-59-245.PMC7583426.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38649211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Slovenian Cross-Cultural Adaptation and Validation of Health-Related Quality of Life Measures for Chronic Otitis Media (COMQ-12), Vertigo (DHI, NVI) and TINNITUS (THI). 慢性中耳炎（COMQ-12）、眩晕（DHI、NVI）和 TINNITUS（THI）与健康相关的生活质量测量的斯洛文尼亚跨文化适应性和验证。

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-06-25 eCollection Date: 2020-09-01 DOI: 10.2478/sjph-2020-0016

Domen Vozel, Nejc Steiner, Nina Božanić Urbančič, Dejan Mladenov, Saba Battelino

{"title":"Slovenian Cross-Cultural Adaptation and Validation of Health-Related Quality of Life Measures for Chronic Otitis Media (COMQ-12), Vertigo (DHI, NVI) and TINNITUS (THI).","authors":"Domen Vozel, Nejc Steiner, Nina Božanić Urbančič, Dejan Mladenov, Saba Battelino","doi":"10.2478/sjph-2020-0016","DOIUrl":"10.2478/sjph-2020-0016","url":null,"abstract":"Purpose: To provide physicians and patients with the tools needed to evaluate patients' problems and health-related quality of life by cross-culturally adapting and validating the Chronic Otitis Media Questionnaire 12 (COMQ-12), the Dizziness Handicap Inventory (DHI), the Neuropsychological Vertigo Inventory (NVI) and the Tinnitus Handicap Inventory (THI).Materials and methods: COMQ-12, DHI, NVI and THI were translated into the Slovenian language and completed by patients treated at our department for chronic otitis media, vertigo or tinnitus. The control group for each questionnaire consisted of healthy volunteers. Internal consistency, test-retest reliability, discriminant validity, diagnostic accuracy and cut-off value were determined for each questionnaire.Results: Test-retest reliability was excellent for DHI (ICC A=0.946) and NVI (p=0.315, ICC A=0.975), good to excellent for COMQ-12 (p=0.680, ICC A=0.858) and satisfactory for THI (p=0.120). Discriminant validity was confirmed for each questionnaire (p>0.05) using the Mann-Whitney U test (COMQ-12, DHI, THI) or the Welch t-test (NVI). COMQ-12 had acceptable (α=0.796) and DHI (α=0.910), NVI (α=0.950) and THI (α=0.924) perfect internal consistency. COMQ-12 and DHI had excellent, NVI acceptable and THI perfect diagnostic accuracy (AUC=0.987, AUC=0.999, AUC=0.781 and AUC=1.000 respectively). Cut-off values determined by Youden's index were 7, 7, 9 and 56 for COMQ-12, THI, DHI and NVI, respectively.Conclusion: Slovenian COMQ-12, DHI, NVI and THI are a valid and accurate tool for the diagnosis and measurement of health-related quality of life in patients with chronic otitis media, vertigo and tinnitus. They could aid general practitioners, occupational health specialists, neurologists and otorhinolaryngologists.","PeriodicalId":45127,"journal":{"name":"Zdravstveno Varstvo","volume":"59 3","pages":"120-127"},"PeriodicalIF":1.5,"publicationDate":"2020-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2a/2d/sjph-59-120.PMC7478096.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38499473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Key Challenges in Modelling an Epidemic - What have we Learned from the COVID-19 Epidemic so Far. 流行病建模的主要挑战——迄今为止，我们从COVID-19流行病中学到了什么?

IF 1.5 4区医学

Zdravstveno Varstvo Pub Date : 2020-06-25 eCollection Date: 2020-09-01 DOI: 10.2478/sjph-2020-0015

Ivan Eržen, Tina Kamenšek, Miha Fošnarič, Janez Žibert

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引用次数: 9