AIMS Bioengineering最新文献

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An overview on platelet concentrates in tissue regeneration in periodontology 血小板在牙周病组织再生中的应用综述
IF 2.3
AIMS Bioengineering Pub Date : 2023-01-01 DOI: 10.3934/bioeng.2023005
Kapil D. Bhangdiya, A. Wankhede, P. Madhu, Amit Reche
{"title":"An overview on platelet concentrates in tissue regeneration in periodontology","authors":"Kapil D. Bhangdiya, A. Wankhede, P. Madhu, Amit Reche","doi":"10.3934/bioeng.2023005","DOIUrl":"https://doi.org/10.3934/bioeng.2023005","url":null,"abstract":"Recent research on the use of platelet concentration in medicinal dentistry has enhanced the potential for tissue regeneration. The ability of platelets to enhance tissue regeneration by using different forms of platelet concentration (blood component) such as platelet-rich plasma (PRP), platelet-rich fibrin (PRF), standard platelet-rich fibrin, advanced platelet-rich fibrin, etc. PRP became widely used once its potential for tissue regeneration was discovered; however, the use of anticoagulants restricted the easy use of PRP as compared to PRF; however, after the discovery of PRF because of the easy formulation, it became widely used in medicinal dentistry. The purpose of this review is to elaborate on the importance of platelet concentration in periodontal regeneration.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"129 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89892994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Detection and analysis of coagulation effect in vein using MEMS laminar flow for the early heart stroke diagnosis MEMS层流检测和分析静脉凝血效果在早期心梗诊断中的应用
IF 2.3
AIMS Bioengineering Pub Date : 2023-01-01 DOI: 10.3934/bioeng.2023001
Vasudeva Reddy Tatiparthi, M. Rao, Santosh Kumar, Hindumathi
{"title":"Detection and analysis of coagulation effect in vein using MEMS laminar flow for the early heart stroke diagnosis","authors":"Vasudeva Reddy Tatiparthi, M. Rao, Santosh Kumar, Hindumathi","doi":"10.3934/bioeng.2023001","DOIUrl":"https://doi.org/10.3934/bioeng.2023001","url":null,"abstract":"The primary objective of the research article is to describe the functionality of wrist watch which acts as a digital stethoscope to measure health constraints such as heart pulse through blood pressure. The second objective is the detection of blockages of an artery due to fatty, cholesterol-deposited, over a period when the blood is passing through due to stress and exercise, etc. Pressure and velocity are two inputs with their respective results of contrast and expansion of veins at the outputs. The major parameters in detecting the laminar flow are pressure and velocity. These parameters of a vein are analyzed by integrating valves in the vein. The movement of blood laminar flow in the vein is captured by a MEMS-based piezoelectric sensor by its functionality. The proposed design performance accuracy is estimated by modeling of vein's laminar flow when blood is circulating. The coagulation effect of the vein is used to measure heart stroke by placing MEMS along with the stent, as MEMS are tiny in size. The functionality of a digital Stethoscope works on the piezoelectric effect that generates an electrical signal when pressure is applied from the vein. The accuracy, functionality, and performance of the design can be analyzed by COMSOL multi-physics. Applications of MEMS include detection, prevention, and alert during the second heart stroke, and also used in the bionic eye and automotive electronics.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"81 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74243431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Enhancing public health strategies for tungiasis: A mathematical approach with fractional derivative 加强对通虫病的公共卫生战略:分数阶导数的数学方法
AIMS Bioengineering Pub Date : 2023-01-01 DOI: 10.3934/bioeng.2023023
Norliyana Nor Hisham Shah, Rashid Jan, Hassan Ahmad, Normy Norfiza Abdul Razak, Imtiaz Ahmad, Hijaz Ahmad
{"title":"Enhancing public health strategies for tungiasis: A mathematical approach with fractional derivative","authors":"Norliyana Nor Hisham Shah, Rashid Jan, Hassan Ahmad, Normy Norfiza Abdul Razak, Imtiaz Ahmad, Hijaz Ahmad","doi":"10.3934/bioeng.2023023","DOIUrl":"https://doi.org/10.3934/bioeng.2023023","url":null,"abstract":"<abstract> <p>In this study, we formulate a mathematical model in the framework of the Atangana-Baleanu fractional derivative in Caputo sense to study the transmission of tungiasis. In this formulation, interactions between the human host and the sand fleas are taken into consideration, including factors like infestation rate, incubation duration, and recovery rate. We calculate the basic reproduction parameter for the system, symbolized by $mathcal{R}_0$ with the help of the next-generation matrix technique. A novel numerical scheme for encapsulating the non-local and memory-dependent aspects of the system is conceptualized via the Atangana-Baleanu fractional derivative. We prove the existence and uniqueness of the solution of the model of the infection and establish stability of the steady-states of the model. In addition to this, numerical simulations are carried out to evaluate the efficiency of interventions like campaigns for better sanitation and treatment, and to investigate the influence of various management techniques on the prevalence of tungiasis. The outcomes of the numerical simulations give us information about the possible efficacy of different control strategies in lowering the incidence of tungiasis. This research gives quantitative tools to enhance decision-making processes in public health treatments and advances our understanding of the dynamics of the tungiasis.</p> </abstract>","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135312433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real data-based optimal control strategies for assessing the impact of the Omicron variant on heart attacks 评估欧米克隆变异对心脏病发作影响的真正基于数据的最优控制策略
IF 2.3
AIMS Bioengineering Pub Date : 2023-01-01 DOI: 10.3934/bioeng.2023015
F. Evirgen, Fatma Özköse, Mehmet Yavuz, N. Özdemir
{"title":"Real data-based optimal control strategies for assessing the impact of the Omicron variant on heart attacks","authors":"F. Evirgen, Fatma Özköse, Mehmet Yavuz, N. Özdemir","doi":"10.3934/bioeng.2023015","DOIUrl":"https://doi.org/10.3934/bioeng.2023015","url":null,"abstract":"This paper presents an investigation into the relationship between heart attacks and the Omicron variant, employing a novel mathematical model. The model incorporates two adjustable control parameters to manage the number of infected individuals and individuals with the Omicron variant. The study examines the model's positivity and boundedness, evaluates the reproduction number (R0), and conducts a sensitivity analysis of the control parameters based on the reproduction number. The model's parameters are estimated using the widely utilized least squares curve fitting method, employing real COVID-19 cases from Türkiye. Finally, numerical simulations demonstrate the efficacy of the suggested controls in reducing the number of infected individuals and the Omicron population.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"22 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72695638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Signal transduction from ligand-receptor binding associated with the formation of invadopodia in an invasive cancer cell 在侵袭性癌细胞中,配体-受体结合的信号转导与侵足形成相关
IF 2.3
AIMS Bioengineering Pub Date : 2022-01-01 DOI: 10.3934/bioeng.2022017
Noorehan Yaacob, S. Shafie, Takashi Suzuki, M. A. Admon
{"title":"Signal transduction from ligand-receptor binding associated with the formation of invadopodia in an invasive cancer cell","authors":"Noorehan Yaacob, S. Shafie, Takashi Suzuki, M. A. Admon","doi":"10.3934/bioeng.2022017","DOIUrl":"https://doi.org/10.3934/bioeng.2022017","url":null,"abstract":"Invadopodia are finger-like protrusions that are commonly spotted at the membrane of the invasive cancer cell. These structures are a major cause of death among cancer patients through metastasis process. Signal transduction stimulated upon contact between ligand and membrane receptors is identified as one of key factors in invadopodia formation. In this study, a time-dependent mathematical model of signal and ligand is investigated numerically. The moving boundary of plasma membrane is taken as a zero-level set function and is moved by the velocity that accounted as the difference of gradient between intra-cellular signal and extra-cellular ligand. The model is solved using a combination of ghost with linear extrapolation and finite difference methods. The results showed that the stimulation of signal from membrane associated ligand consequently moved the plasma membrane outward as time increases. The highest densities of signal and ligand are recorded on the membrane and slowly diffused into intra-cellular and extra-cellular regions, respectively.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"9 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90040668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of “natural therapy” technology in the framework of social and psychological rehabilitation of the elderly “自然疗法”技术在老年人社会心理康复框架中的应用
IF 2.3
AIMS Bioengineering Pub Date : 2022-01-01 DOI: 10.3934/bioeng.2022022
M. Anishchenko, Ellina G. Pozdniakova-Kyrbiatieva, Y. Mosaiev, O. Krasnokutskyi, Volodymyr V. Glazunov
{"title":"Use of “natural therapy” technology in the framework of social and psychological rehabilitation of the elderly","authors":"M. Anishchenko, Ellina G. Pozdniakova-Kyrbiatieva, Y. Mosaiev, O. Krasnokutskyi, Volodymyr V. Glazunov","doi":"10.3934/bioeng.2022022","DOIUrl":"https://doi.org/10.3934/bioeng.2022022","url":null,"abstract":"The article is devoted to the peculiarities of using “natural therapy” technology in the process of social and psychological rehabilitation of the elderly. The article analyzes the relevance of the problem of social isolation, maladaptation and loneliness of elderly people in different countries of the world, and in Ukraine in particular, leading to sustainable social and psychological dysfunctions and substantiates the need to overcome them. The author's methodology for evaluating the effectiveness of socio-psychological rehabilitation sessions with the elderly using the rehabilitation implements of natural therapy is proposed. The mechanisms and technologies of social and psychological rehabilitation of the elderly using the rehabilitation concept of natural therapy are proposed and have been tested. As part of the research, an experiment was conducted among 100 people, half of whom were engaged in an individual rehabilitation course using the technology of the ecological rehabilitation concept of natural therapy. The article describes the results of the proposed classes for the participants of the experimental group and presents proposals in the field of improving rehabilitation measures based on natural therapy in the framework of the social and psychological rehabilitation of the elderly.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"44 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72612952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surveillance of elderlies at home: sensors, portable medical imaging devices, medical data management on smart phone 监测家中老人:传感器、便携式医疗成像设备、智能手机医疗数据管理
IF 2.3
AIMS Bioengineering Pub Date : 2022-01-01 DOI: 10.3934/bioeng.2022026
J. Demongeot, K. Oshinubi
{"title":"Surveillance of elderlies at home: sensors, portable medical imaging devices, medical data management on smart phone","authors":"J. Demongeot, K. Oshinubi","doi":"10.3934/bioeng.2022026","DOIUrl":"https://doi.org/10.3934/bioeng.2022026","url":null,"abstract":"<jats:p xml:lang=\"fr\" />","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"30 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82777256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Computational simulations of the effects of social distancing interventions on the COVID-19 pandemic 社交距离干预措施对COVID-19大流行影响的计算模拟
IF 2.3
AIMS Bioengineering Pub Date : 2022-01-01 DOI: 10.3934/bioeng.2022016
S. Khoshnaw, A. S. Mohammed
{"title":"Computational simulations of the effects of social distancing interventions on the COVID-19 pandemic","authors":"S. Khoshnaw, A. S. Mohammed","doi":"10.3934/bioeng.2022016","DOIUrl":"https://doi.org/10.3934/bioeng.2022016","url":null,"abstract":"The spread of the COVID-19 pandemic has been considered as a global issue. Based on the reported cases and clinical data, there are still required international efforts and more preventative measures to control the pandemic more effectively. Physical contact between individuals plays an essential role in spreading the coronavirus more widely. Mathematical models with computational simulations are effective tools to study and discuss this virus and minimize its impact on society. These tools help to determine more relevant factors that influence the spread of the virus. In this work, we developed two computational tools by using the R package and Python to simulate the COVID-19 transmissions. Additionally, some computational simulations were investigated that provide critical questions about global control strategies and further interventions. Accordingly, there are some computational model results and control strategies. First, we identify the model critical factors that helps us to understand the key transmission elements. Model transmissions can significantly be changed for primary tracing with delay to isolation. Second, some types of interventions, including case isolation, no intervention, quarantine contacts and quarantine contacts together with contacts of contacts are analyzed and discussed. The results show that quarantining contacts is the best way of intervening to minimize the spread of the virus. Finally, the basic reproduction number R0 is another important factor which provides a great role in understanding the transmission of the pandemic. Interestingly, the current computational simulations help us to pay more attention to critical model transmissions and minimize their impact on spreading this disease. They also help for further interventions and control strategies.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"38 1 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85396887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Spatial mechanistic modeling for prediction of 3D multicellular spheroids behavior upon exposure to high intensity pulsed electric fields 高强度脉冲电场作用下三维多细胞球体行为预测的空间机制建模
IF 2.3
AIMS Bioengineering Pub Date : 2022-01-01 DOI: 10.3934/bioeng.2022009
Annabelle Collin, Hadrien Bruhier, Jelena Kolosnjaj, M. Golzio, M. Rols, C. Poignard
{"title":"Spatial mechanistic modeling for prediction of 3D multicellular spheroids behavior upon exposure to high intensity pulsed electric fields","authors":"Annabelle Collin, Hadrien Bruhier, Jelena Kolosnjaj, M. Golzio, M. Rols, C. Poignard","doi":"10.3934/bioeng.2022009","DOIUrl":"https://doi.org/10.3934/bioeng.2022009","url":null,"abstract":"The objective of this work was to investigate the growth specificities of cancer cells spheroids subjected to pulsed electric field. Multicellular HCT-116-GFP spheroids were exposed to different electric field intensities and the volume of multicellular spheroids was monitored by fluorescence and bright field microscopy. Thanks to an advanced mathematical model, based on differential equations and well-adapted estimation strategies, our modeling enables us to characterize the multicellular spheroids growth after permeabilizing pulsed electric field. In particular, we identify the percentage of cells which are destroyed and the percentage of cells which exhibit an altered growth pattern for different magnitudes of the electric field. We also quantify the growth resumption upon reversible and partially irreversible electroporation. Our preliminary results provide a first quantification of the impact of electroporation on multicellular spheroids growth, and suggest a booming growth of partially irreversible electric pulses, leading to an accelerated regrowth.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"51 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87871149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sulfated polysaccharide-rich extract from Navicula incerta: physicochemical characteristics, antioxidant activity, and anti-hemolytic property 海navicula的硫酸酸化多糖提取物:理化特性、抗氧化活性和抗溶血性能
IF 2.3
AIMS Bioengineering Pub Date : 2022-01-01 DOI: 10.3934/bioeng.2022027
R. González-Vega, C. L. Del‐Toro‐Sánchez, R. Moreno-Corral, J. A. López-Elías, Aline Reyes-Díaz, Norma García-Lagunas, E. Carvajal‐Millan, Diana Fimbres-Olivarría
{"title":"Sulfated polysaccharide-rich extract from Navicula incerta: physicochemical characteristics, antioxidant activity, and anti-hemolytic property","authors":"R. González-Vega, C. L. Del‐Toro‐Sánchez, R. Moreno-Corral, J. A. López-Elías, Aline Reyes-Díaz, Norma García-Lagunas, E. Carvajal‐Millan, Diana Fimbres-Olivarría","doi":"10.3934/bioeng.2022027","DOIUrl":"https://doi.org/10.3934/bioeng.2022027","url":null,"abstract":"A sulfated polysaccharide from Navicula incerta (SPNi) was extracted, and its physicochemical characteristics, antioxidant activity, and anti-hemolytic property were investigated. The polysaccharide yield was 4.8% (SPNi weight/biomass dry weight). Glucose, galactose, mannose, and xylose were the primary sugars. The sulfate content and Mw values were 0.46% and 45 kDa, respectively. The FT-IR spectrum showed characteristic bands at 3276,1079,1255, and 820 cm−1, related to -OH, C-O-C, S=O, and C-O-S stretching vibration. The 1H-NMR analysis revealed signals of anomeric protons, indicating the presence of CH2-O and CH-O groups. SPNi registered ferric-reducing antioxidant power (up to 1.47 µmol TE/g) and 54% anti-radical activity on ABTS+. This polysaccharide registered 90% hemolysis inhibition achieving integrity of the erythrocyte membrane. The results indicate that SPNi could be a candidate for biotechnology applications where antioxidant activity and hemolysis inhibition are required.","PeriodicalId":45029,"journal":{"name":"AIMS Bioengineering","volume":"1 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88352406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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