Academic Pathology最新文献_第10页

Diagnostic yield and repeat biopsies in rectal and nonrectal colorectal adenocarcinoma: Are we hedging on rectal biopsies? 直肠和非直肠结直肠腺癌的诊断率和重复活检:我们是否要对直肠活检进行回避?

IF 1

Academic Pathology Pub Date : 2023-01-01 DOI: 10.1016/j.acpath.2022.100063

Michel Kmeid MD , Rupinder Brar MD , Luz Sullivan MD , Mustafa Erdem Arslan MD , Neharika Shrestha MD , Edward C. Lee MD , Anne Chen MD , Timothy A. Jennings MD , Hwajeong Lee MD

{"title":"Diagnostic yield and repeat biopsies in rectal and nonrectal colorectal adenocarcinoma: Are we hedging on rectal biopsies?","authors":"Michel Kmeid MD , Rupinder Brar MD , Luz Sullivan MD , Mustafa Erdem Arslan MD , Neharika Shrestha MD , Edward C. Lee MD , Anne Chen MD , Timothy A. Jennings MD , Hwajeong Lee MD","doi":"10.1016/j.acpath.2022.100063","DOIUrl":"10.1016/j.acpath.2022.100063","url":null,"abstract":"<div><p>Patients with rectal cancer undergo more repeat biopsies compared to those with nonrectal colon cancer prior to management. We investigated the factors driving the higher frequency of repeat biopsies in patients with rectal cancer. We compared clinicopathologic features of diagnostic and nondiagnostic (in regard to invasion) rectal (n = 64) and colonic (n = 57) biopsies from colorectal cancer patients and characterized corresponding resections. Despite similar diagnostic yield, repeat biopsy was more common in rectal carcinoma, especially in patients receiving neoadjuvant therapy (p < 0.05). The presence of desmoplasia (odds ratio 12.9, p < 0.05) was a strong predictor of making a diagnosis of invasion in both rectal and nonrectal colon cancer biopsies. Diagnostic biopsies had more desmoplasia, intramucosal carcinoma component and marked inflammation, and less low-grade dysplasia component (p < 0.05). Diagnostic yield of biopsy was higher for tumors with high-grade tumor budding, mucosal involvement by high-grade dysplasia/intramucosal carcinoma without low-grade dysplasia and diffuse surface desmoplasia irrespective of tumor location. Sample size, amount of benign tissue, appearance, and T stage did not affect diagnostic yield. Repeat biopsy of rectal cancer is primarily driven by management implications. Diagnostic yield in colorectal cancer biopsies is multifactorial and is not due to differing pathologists’ diagnostic approach per tumor site. For rectal tumors, a multidisciplinary strategic approach is warranted to avoid repeat biopsy when unnecessary.</p></div>","PeriodicalId":44927,"journal":{"name":"Academic Pathology","volume":"10 1","pages":"Article 100063"},"PeriodicalIF":1.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9198895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Supporting a culture of patient safety: Resident-led patient safety event reviews in a pathology residency training program 支持患者安全文化：病理住院医师培训项目中住院医师领导的患者安全事件审查

IF 1

Academic Pathology Pub Date : 2023-01-01 DOI: 10.1016/j.acpath.2023.100069

Catherine M. Tucker MD , Rebecca Jaffe MD , Allison Goldberg MD

{"title":"Supporting a culture of patient safety: Resident-led patient safety event reviews in a pathology residency training program","authors":"Catherine M. Tucker MD , Rebecca Jaffe MD , Allison Goldberg MD","doi":"10.1016/j.acpath.2023.100069","DOIUrl":"10.1016/j.acpath.2023.100069","url":null,"abstract":"<div><p>Patient safety is a critical component of quality patient care at any healthcare institution. In order to support a culture of patient safety, and in the context of a hospital-wide patient safety initiative at our institution, we have created and implemented a new patient safety curriculum within our training program. The curriculum is embedded in an introductory course for first-year residents, in which residents gain an understanding of the multifaceted role of the pathologist in patient care. The patient safety curriculum is a resident-centered event review process and includes 1) identification and reporting of a patient safety event, 2) event investigation and review, and 3) presentation of findings to the residency program including core faculty and safety champions for the consideration of implementation of the identified systems solution. Here we discuss the development of our patient safety curriculum, which was trialed over a series of seven event reviews conducted between January 2021 and June 2022. Resident involvement in patient safety event reporting and patient safety event review outcomes were measured. All event reviews conducted thus far have resulted in the implementation of the solutions discussed during event review presentations based on cause analysis and identification of strong action items. Ultimately this pilot will serve as the basis by which we implement a sustainable curriculum in our pathology residency training program centered on supporting a culture of patient safety, and in line with ACGME requirements.</p></div>","PeriodicalId":44927,"journal":{"name":"Academic Pathology","volume":"10 1","pages":"Article 100069"},"PeriodicalIF":1.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10844500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Undergraduate medical student perspectives on the role of autopsy in medical education 本科医学生对尸检在医学教育中的作用的看法

IF 1

Academic Pathology Pub Date : 2023-01-01 DOI: 10.1016/j.acpath.2022.100068

Patrick Hearle , Wing Fei Wong AB , Joanna Chan MD

{"title":"Undergraduate medical student perspectives on the role of autopsy in medical education","authors":"Patrick Hearle , Wing Fei Wong AB , Joanna Chan MD","doi":"10.1016/j.acpath.2022.100068","DOIUrl":"10.1016/j.acpath.2022.100068","url":null,"abstract":"<div><p>Medical autopsy has historically been considered a valued experience in undergraduate medical education; however, student participation has declined in recent years. Medical education literature from the educator point of view supports autopsy as an educational tool, but more data are needed on undergraduate medical students’ (UMS) perspectives on autopsy. This study aims to assess UMS opinions on the role of autopsy in undergraduate medical education. A 5-point Likert scale survey concerning autopsy and medical education was offered to all UMS at Sidney Kimmel Medical College. In addition, 28 senior students were assigned a 500 word essay on hospital autopsy and its role in medical education. Senior students were given the opportunity to view an autopsy prior to completing their essays. UMS (n = 87) reported that witnessing an autopsy can improve anatomic knowledge (μ = 4.3), observational skills (μ = 4.1), and clinicopathologic correlation (μ = 4.3) but were neutral in their perceived importance of viewing an autopsy in their pathology education (μ = 3.7). Senior students (n = 27) responding to the essay prompt reported that autopsy is essential in medical education (85.2%) and increases clinical and anatomical understanding (63.0%). This study suggests that many UMS acknowledge the importance and applicability of autopsy in their education. This concurrence of UMS opinion with the medical education literature supports making autopsy participation a widely available component of undergraduate medical education.</p></div>","PeriodicalId":44927,"journal":{"name":"Academic Pathology","volume":"10 1","pages":"Article 100068"},"PeriodicalIF":1.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9306894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Educational Case: Osteoporosis 教育案例:骨质疏松症

IF 1

Academic Pathology Pub Date : 2022-01-01 DOI: 10.1016/j.acpath.2022.100050

Jonathan Light MS , Harrison Klause MD , Richard M. Conran MD, PhD, JD

引用次数: 0

Educational Case: Transfusion reactions: Transfusion associated circulatory overload vs transfusion-related acute lung injury 教育案例:输血反应:输血相关循环负荷vs输血相关急性肺损伤

IF 1

Academic Pathology Pub Date : 2022-01-01 DOI: 10.1016/j.acpath.2022.100022

Diana S. Desai MD, MBA , Kinjal S. Shah MD , Sejal A. Shah MD

引用次数: 0

Educational Case: Renal allograft rejection 教育案例:肾移植排斥反应

IF 1

Academic Pathology Pub Date : 2022-01-01 DOI: 10.1016/j.acpath.2022.100013

Harrison Dai BS , Shirui Chen MD , Jolanta Kowalewska MD, PhD

引用次数: 0

Educational Case: Evaluating a patient with cirrhosis 教育案例:评价一个肝硬化患者

IF 1

Academic Pathology Pub Date : 2022-01-01 DOI: 10.1016/j.acpath.2022.100031

Tyler J. Reed BA, Danielle D'Ambrosio MD, Barbara E.C. Knollmann-Ritschel MD

引用次数: 0

Educational Case: Lambert–Eaton syndrome 教育案例:兰伯特-伊顿综合症

IF 1

Academic Pathology Pub Date : 2022-01-01 DOI: 10.1016/j.acpath.2022.100021

Austin Huddleston (BS), Larry Nichols (MD)

引用次数: 0

The pathology fellowship application crisis: The current state and suggestions for remediation 病理学奖学金申请危机:现状及补救建议

IF 1

Academic Pathology Pub Date : 2022-01-01 DOI: 10.1016/j.acpath.2022.100029

Amanda C. Herrmann MD, PhD , Cheryl Hanau MD , Donald Karcher MD , Douglas C. Miller MD, PhD , Alexandra Murtha , Ashley E. Sanders PHR, SHRM-CP , Charles Timmons MD, PhD , Karen L. Kaul MD, PhD , a work group of the Association of Pathology Chairs' Graduate Medical Education Committee

引用次数: 2

Academic Pathology's “Spiderless Network”: The power of a professional society, its listserv, and its journal during a public health emergency 学术病理学的“无蜘蛛网络”:在突发公共卫生事件中，一个专业学会、它的列表服务和它的期刊的力量

IF 1

Academic Pathology Pub Date : 2022-01-01 DOI: 10.1016/j.acpath.2022.100044

Mark L. Tykocinski MD (President, Dean, Professor)

引用次数: 0