V.F.Snegirev Archives of Obstetrics and Gynecology最新文献

{"title":"INFLUENCE OF PROFESSIONAL FACTORS ON THE DEVELOPMENT OF GYNECOLOGICAL PATHOLOGY IN FLIGHT ATTENDANCE IN CIVIL AVIATION","authors":"L. Ozolinya, N. I. Nasyrova, A. Y. Yurovskij, A. V. Overko","doi":"10.17816/aog626363","DOIUrl":"https://doi.org/10.17816/aog626363","url":null,"abstract":"The literature review reflects the main possible gynecological pathologies in flight attendants, as well as the causes of their occurrence. These diseases are a serious problem for all women, but professionals working in the aviation industry are at a higher risk of developing them. The article focuses on the study of various factors that can contribute not only to the development of gynecological diseases, but also to breast cancer, as well as venous thrombosis in flight attendants. Risk factors include long-term exposure to ionizing radiation, static stress, jet lag, and chronic stress. The review includes an analysis of existing studies related to the impact of occupational exposure on the health of flight attendants, and also suggests possible measures for the prevention and treatment of emerging pathology, which can serve as a basis for the development of effective programs to preserve the health of women working in civil aviation.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"2 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Errors in the diagnosis of intraepithelial lesions and cervical cancer and modern opportunities to improve the quality of primary screening","authors":"Elena V. Kolomeets, Lyudmila P. Tarasova, Tal'yana D. Potekhina, Elena V. Virivskaya, Kamil’ R. Bakhtiyarov","doi":"10.17816/2313-8726-2024-11-1-57-67","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-57-67","url":null,"abstract":"The high prevalence of precancerous pathologies and cervical cancer indicates their relevance. Cervical cancer ranks fourth among the causes of mortality of women with cancer worldwide and second in women aged 15–44 years. According to the World Health Organization, approximately 500 thousand new cases of cervical cancer are diagnosed annually worldwide. In Russia, more than 15 thousand new cases are registered annually, and nearly half of them (47.8%) end in death. The increase in the frequency of advanced stages and the increase in mortality among women of reproductive age are of particular concern. According to statistical data from the oncology database of the Moscow Hertzen Cancer Research Institute, the incidence of cervical cancer over 10 years increased by 2.12% annually. \u0000This article presents the results of the statistical analysis of data for assessing the incidence of precancer pathologies and cervical cancer and discusses trends in the spread and juvenation of this pathology as well as its causes. The results of the analysis of errors in diagnosing intraepithelial lesions and modern possibilities for its optimization are also presented.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"714 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140718911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magneto-infrared-light-laser therapy and ozone therapy in the complex treatment of salpingo-oophoritis after medical abortion","authors":"Asiyat E. Esedovna, A.Yu. Islamova","doi":"10.17816/2313-8726-2024-11-1-77-82","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-77-82","url":null,"abstract":"Background. Complications following artificial abortion can lead to reproductive dysfunction and gynecological diseases, endocrine disorders, infertility, and miscarriage. One of the most important tasks of practical healthcare is the introduction of safer abortions and an adequate rehabilitation system, including early, as well as ultrasound, diagnostics of emerging complications, into the practice of obstetricians and gynecologists. \u0000Materials and methods. The study included 124 female patients (average age, 34.8+1.7 years) who applied for pregnancy termination in the first trimester. The women were divided into three groups. Group 1 included 52 (42.0%) female patients who received magnetic-infrared-light-laser and ozone therapy to prevent complications following a medical abortion in a complex of therapeutic measures with antibacterial drugs. Group 2 included 24 (19.3%) patients who had dysbiosis, allergic reactions, and drug disease and who used magnetic-infrared-light-laser and ozone therapy without antibiotics to prevent postabortion complications. The control subgroup comprised 48 (38.7%) patients who did not receive treatment for the prevention of complications. \u0000Results. A more rapid change in the size of the uterus toward normalization was noted in women in groups 1 and 2 who received preventive measures. In addition, 1 (2.0%) patient in group 1, 1 (4.1%) in group 2, and 3 (6.2%) in the control group had an exacerbation of bilateral chronic salpingo-oophoritis. \u0000Conclusions. The use of modern technologies (magnetic-infrared-light-laser and medical ozone therapy) with and without antibacterial therapy as preventive measures has a positive effect on uterine contractility and reduces the risk of inflammatory complications in the first months following artificial termination of pregnancy. Ultrasonography of the pelvic organs and laser biophotometer can be used as diagnostic tests and can assess the development of complications following a medical abortion.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"150 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140719789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the microbiome as a factor in the development of isthmic cervical insufficiency","authors":"Kamil’ R. Bakhtiyarov, Afet S. Abdulaeva, Makka B. Bimurzayeva, Daria V. Korolyova, Polina I. Kuzmina","doi":"10.17816/2313-8726-2024-11-1-49-56","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-49-56","url":null,"abstract":"The status of a woman’s cervicovaginal microbiome may correlate with the risk of obstetric complications such as isthmic cervical insufficiency (ICI) and preterm delivery (PD). This review examined the relationship between the microbiome and ICI. The dominance of Lactobacillus crispatus and, possibly, L. gasseri in the microbiome was associated with full-term pregnancy, whereas the predominance of other Lactobacillus species and anaerobic bacteria led to the preterm rupture of membranes and PD. Notably, high levels of the antimicrobial peptide β-defensin 2, even without L. crispatus dominance, are also associated with full-term pregnancy. The analysis of the cervicovaginal and amniotic fluids of women who subsequently gave birth prematurely revealed an increase in the levels of proinflammatory cytokines, such as interleukin (IL)-2, IL-8, and IL-10. Changes in the microbiome composition and an increase in the maternal immune response lead to premature remodeling and softening of the cervix, i.e. ICI. Thus, early detection of changes in the cervicovaginal microbiome and cervicovaginal and amniotic fluids may be a prognostic marker for ICI and PD.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"185 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140719754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro fertilization for endometriosis-associated infertility: A literature review","authors":"Emilia A. Sarkisyan, E. Svidinskaya, M. B. Ageev, E. A. Sosnova","doi":"10.17816/2313-8726-2024-11-1-7-16","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-7-16","url":null,"abstract":"This article analyzed the work of Russian and international authors over the past 10 years on the effect of endometriosis on the development of infertility and evaluated studies on the analysis of in vitro fertilization procedures in patients with this condition. Every third patient who uses assisted reproductive technology (ART) suffers from endometriosis-associated infertility. Endometriosis is a significant cause of this disease, and its clinical forms and the degree of foci spread often limit doctors’ choice of ART programs, which do not always result in pregnancy. Cystic ovarian endometriosis is one of the most common forms of endometriosis. Controversy surrounds the treatment of this form; some authors advocate hormonal therapy (to preserve the ovarian reserve), whereas others believe that more radical surgical treatment helps reduce relapses. In any case, several factors must be considered when choosing the optimal treatment approach for women with ovarian endometriosis and infertility, including the age of the patient, presence of pain, outcomes of previous surgeries, size and number of cysts, preserved ovarian reserve, and access to the follicles. These factors prove the relevance of this condition, which requires a modern approach to its diagnosis and treatment.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140716772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peritoneal adhesions in modern surgery","authors":"Yulia D. Davydova, Anton A. Fedorov, A. A. Popov, S. Tyurina, Marina A. Chechneva, Yuliya I. Sopova","doi":"10.17816/2313-8726-2024-11-1-17-24","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-17-24","url":null,"abstract":"Adhesions are an urgent and unsolved problem in modern surgery. Any surgical intervention on the abdominal cavity inevitably leads to the formation of adhesions, which are fibrous cords between abdominal organs, resulting from trauma to the peritoneum of any etiology. Despite the improvement of surgical approaches and techniques, methods that prevent adhesiogenesis at its earliest stages and an integrated approach to rehabilitation in the postoperative period, as well as morbidity associated with the adhesive process of the abdominal cavity, remain widespread. The clinical presentation of the pathological process is polymorphic; treatment requires significant effort and resources; and adhesiogenesis-induced complications have a high medical and social significance, cause harm to the healthcare economy, and negatively affect the quality of life of patients. \u0000At present, unified methods and classifications for assessing the severity and prevalence of adhesions in the abdominal cavity, concepts for preventing the formation of adhesions that affect the key links of pathogenesis, and noninvasive mechanisms for their early detection in the postoperative period, which determines the need for interdisciplinary multicenter studies in this field, have not been developed.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"1987 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140719225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HELLP syndrome as an interdisciplinary problem. Clinical observation","authors":"I. Gadaeva, I. Gadaev, Anna D. Koryagina, Kseniya A. Rossolovskaya","doi":"10.17816/2313-8726-2024-11-1-89-100","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-89-100","url":null,"abstract":"Thrombotic microangiopathy (TMA) is an important component in obstetric practice. Despite this, patients with suspected TMA should be under the supervision of not only an obstetrician-gynecologist, but also related specialists such as a hematologist, nephrologist, cardiologist, therapist, etc. The main types of TMA found in pregnant women are thrombotic thrombocytopenic purpura (TTP), catastrophic antiphospholipid syndrome (KAFS), atypical hemolytic-uremic syndrome (aHUS), preeclampsia (PE) and HELLP syndrome. The most common TMA, according to world literature, is HELLP syndrome, which, in turn, in 10-20% of cases is a complication of severe preeclampsia. In this article, we reviewed the clinical observation of the development of HELLP syndrome in a 32-year-old woman with a severe form of preeclampsia. The features of the differential diagnosis in the framework of thrombotic microangiopathy with predominant kidney damage were demonstrated. We have analyzed the issues of the origin of HELLP syndrome and the methods of treatment. This article discusses modern approaches to the diagnosis of a group of thrombotic microangiopathies found in obstetric practice. An interdisciplinary approach involving specialists such as a hematologist, a nephrologist, a clinical pharmacologist, a cardiologist, a therapist and a hemotransfusiologist is extremely important for the differential diagnosis of HELLP syndrome in a patient with severe preeclampsia, which allows you to get a positive result from timely and well-chosen therapy. The end result is a reduction in both maternal and perinatal mortality.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"2005 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140718606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopausal hormone therapy and Alzheimer’s disease: A literature review","authors":"Yuliya V. Luzik, S. Isaeva, E. Svidinskaya, M. B. Ageev, E. A. Sosnova","doi":"10.17816/2313-8726-2024-11-1-25-34","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-25-34","url":null,"abstract":"This paper presents a review of the current literature on the possible relationship between menopausal hormone therapy and Alzheimer’s disease. Increasing life expectancy in modern society is steadily leading to health problems in older women. Approximately 46.8 million people worldwide currently have cognitive disorders, and 2/3 of them are women. At the age of ≥65 years, every sixth woman and every eleventh man experience a form of higher nervous system pathologies. Older people are most often diagnosed with Alzheimer’s disease. It is a neurodegenerative disease that leads to problems with memory and cognitive functions and is characterized by changes in behavior and social-adaptive position of a person in society. \u0000One theory states that dementia is caused by changes in the endocrine status during menopause, particularly a decrease in estrogen levels. Currently, hormonal drugs are being considered a way to reduce the risk of neurological disorders. The possibility of preventing dementia, particularly Alzheimer’s disease, has long been of interest to leading experts in this field. The prevention of these diseases and prolongation of active longevity are becoming more relevant than ever. The relationship between menopausal hormone therapy and the risk of Alzheimer’s disease is receiving increasing attention.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"667 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140719041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful thrombolysis for pulmonary embolism during pregnancy","authors":"E. Timokhina, I. Ignatko, Alina B. Samara, E. L. Muravina, Yulia A. Samoilova","doi":"10.17816/2313-8726-2024-11-1-83-88","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-83-88","url":null,"abstract":"Pulmonary embolism is a serious and potentially life-threatening condition, particularly during pregnancy, and is one of the leading causes of maternal mortality. \u0000A 40-year-old female patient at 27–28 weeks of pregnancy was admitted to the hospital with complaints of shortness of breath at rest, dizziness, and loss of consciousness. Three days before admission, she suddenly felt nagging pain in the groin area, which was aggravated by walking. Contrast-enhanced computed tomography (CT) of the chest revealed CT signs of massive thromboembolism of the pulmonary artery. The Qanadli index was 67.5%. Duplex scanning of the veins of the lower extremities revealed thrombosis of the left common femoral vein with a flotation of 6 cm. Following a multidisciplinary consultation, systemic thrombolysis with Alteplase at a dose of 100 mg once was initiated according to vital indications. Improvement was immediately noted in the first hours after thrombolytic therapy. The efficiency of the therapy and satisfactory condition of the mother and fetus extended the pregnancy to 38 weeks. At full term, the patient underwent a successful cesarean section. The postpartum period proceeded without thromboembolic complications during anticoagulant therapy. \u0000This clinical case demonstrates that timely systemic thrombolysis can prolong pregnancy to full term and preserve the life and health of the mother and fetus.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"553 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140719281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of the program for the accelerated recovery of postpartum women on the microviscosity of the erythrocyte membranes after cesarean section","authors":"D. Medzhidova, Shifman M. Efim, Asniyat U. Cherkesova, Dilara U. Cherkesova","doi":"10.17816/2313-8726-2024-11-1-69-76","DOIUrl":"https://doi.org/10.17816/2313-8726-2024-11-1-69-76","url":null,"abstract":"Background. This study aimed to analyze the microviscosity of membranes and the surface charge of erythrocytes and blood plasma proteins using fluorescent zones in pregnant women before and after cesarean section (CS) with traditional management of the perioperative period and use of an accelerated recovery program. \u0000Materials and methods. The study included pregnant women without somatic or obstetric complications. They were divided into groups that received traditional management during the perioperative period (fasting for 8 h before surgery and administration of an antibiotic after clamping the umbilical cord) and used an accelerated recovery program. The relative microviscosity of the erythrocyte membranes was assessed using the lateral diffusion method with a hydrophobic pyrene probe (C16H10). The surface charge of erythrocytes and blood plasma proteins was determined using the fluorescent probe 8-anilino-1-naphthalene sulfonic acid. \u0000Results. In postpartum women with an accelerated recovery program, the immersion of proteins in the lipid bilayer of the erythrocyte membrane decreased. The coefficient of pyrene eximerization in areas of protein–lipid contacts in the same group was higher and further increased both after anesthesia and after surgery. In the traditional management group, an increase in the eximerization coefficient was registered only after CS. In the areas of lipid–lipid contacts, the coefficient of pyrene eximerization in the accelerated recovery program group was significantly higher than that in the control group. Changes in the eximerization coefficient after anesthesia and surgery were insignificant. Moreover, the polarity of the microenvironment of both anular lipids and total lipids did not change. \u0000Conclusions. An increase in the pyrene eximerization coefficient in patients on an accelerated recovery program indicates a decrease in the microviscosity of erythrocyte membranes and an increase in their fluidity, which may be due to structural rearrangements of cell membranes and leads to an increase in their functional activity. The components of the accelerated recovery program affect the microviscosity of erythrocyte membranes, particularly in the areas of protein–lipid contacts, which may positively affect microcirculation in the perioperative period, which plays a significant role in the genesis of postoperative complications.","PeriodicalId":448378,"journal":{"name":"V.F.Snegirev Archives of Obstetrics and Gynecology","volume":"349 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140719612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}