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Miscellaneous conditions, including autoinflammatory syndromes 杂症，包括自身炎症综合征
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-10-01 DOI: 10.1093/med/9780198789529.003.0014
G. Spickett
{"title":"Miscellaneous conditions, including autoinflammatory syndromes","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0014","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0014","url":null,"abstract":"This chapter covers the presentation, immunogenetics, immunopathology, diagnosis, treatment, and testing for a range of miscellaneous diseases not covered in other parts of the book.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122071473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmunity affecting the nervous system 影响神经系统的自身免疫
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-10-01 DOI: 10.1093/med/9780198789529.003.0005
G. Spickett
{"title":"Autoimmunity affecting the nervous system","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0005","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0005","url":null,"abstract":"This chapter covers a range of autoimmune conditions affecting the nervous system. It describes the presentation, immunogenetics, immunopathology, related autoantibodies, treatment, and testing for each example. It also covers the demyelinating diseases (including MS, Guillian-Barré Syndrome, and uncommon variants), neuropathies, and autoimmunity in other neurological diseases.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"70 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114087118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transplantation 移植
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780198789529.003.0015
G. Spickett
{"title":"Transplantation","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0015","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0015","url":null,"abstract":"This chapter covers the indications, methods, immunological considerations, and monitoring of various types of transplantation. Covering stem cell transplantation, gene therapy, graft vs host disease, graft failure, and solid organ transplantation, the chapter provides an immunological overview of the subject.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125896731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunochemistry 免疫化学
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780199603244.003.0017
G. Spickett
{"title":"Immunochemistry","authors":"G. Spickett","doi":"10.1093/med/9780199603244.003.0017","DOIUrl":"https://doi.org/10.1093/med/9780199603244.003.0017","url":null,"abstract":"This chapter covers the basic techniques used in immunochemistry, including electrophoresis, immunoelectrophoresis, immunofixation, isoelectric focusing, and immunoblotting. It then specifies the units, normal ranges, test principles, and indications for over 50 immunological tests.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132866973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunotherapy 免疫疗法
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780198789529.003.0016
G. Spickett
{"title":"Immunotherapy","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0016","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0016","url":null,"abstract":"This chapter gives an overview of the complex area of immunotherapy. It covers the major mechanisms of immunomodulation, the generation of the immune response, modern approaches to vaccine development, and the basics of replacement therapy. It highlights immunosuppressive or immunomodulatory drugs and biologicals by type, as well as allergy interventions.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"34 15","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120988327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoantibodies 自身抗体
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780198789529.003.0018
G. Spickett
{"title":"Autoantibodies","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0018","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0018","url":null,"abstract":"There are many hundreds of reported autoantibodies, not all of clinical value. The repertoire of the typical regional immunology laboratory will cover most of the ones described within this chapter. Some will only be available through specialist referral laboratories, or through research laboratories. This chapter covers techniques, then the units, principles, indications, and interpretation for tests for individual autoantibodies.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125817319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary immunodeficiency 原发性免疫缺陷
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780198789529.003.0001
G. Spickett
{"title":"Primary immunodeficiency","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0001","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0001","url":null,"abstract":"In general, immunodeficiencies are divided into those of the specific immune system (e.g. T cells or B cells or combined) or those of the innate or non-specific immune system (e.g. complement and neutrophils). Immunodeficiencies may also be divided into primary (usually genetic) and secondary, where the immune defect is caused by some other non-immunological disease. This chapter describes the classification and clinical features of primary immunodeficiencies, and then the cause, presentation, diagnosis, immunology, and treatment for a wide range of immunodeficiencies.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123115831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tissue typing 组织类型
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780198789529.003.0021
G. Spickett
{"title":"Tissue typing","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0021","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0021","url":null,"abstract":"Covering tissue typing, this chapter describes key elements for tissue matching, a key element for successful transplantation. Methods for detecting pre-formed circulating antibodies, serological tests, and genotyping are all described. Techniques including RFLP, PCR, sequence-specific primer are explained, along with a look forward to next-generation sequencing.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"321 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124541373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cellular investigations 手机的调查
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780198789529.003.0020
G. Spickett
{"title":"Cellular investigations","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0020","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0020","url":null,"abstract":"This chapter covers cellular investigations, including identification of cell surface phenotype, intracellular proteins, cellular function, secreted products, and abnormal constituents. Techniques are described, along with principles for testing and interpretation of the results.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126420024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allergy tests 过敏测试
Oxford Handbook of Clinical Immunology and Allergy Pub Date : 2019-09-01 DOI: 10.1093/med/9780198789529.003.0019
G. Spickett
{"title":"Allergy tests","authors":"G. Spickett","doi":"10.1093/med/9780198789529.003.0019","DOIUrl":"https://doi.org/10.1093/med/9780198789529.003.0019","url":null,"abstract":"This chapter describes allergy tests, including their principles for testing, indications, and methods of interpreting the assays and tests. Limitations are also covered, along with key recombinant allergens for common substances that provoke an allergic reaction.","PeriodicalId":448046,"journal":{"name":"Oxford Handbook of Clinical Immunology and Allergy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125426537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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