{"title":"Response to \"Analysis of possible risk predictors in patients with coronavirus disease 2019: a retrospective cohort study\"","authors":"Marium Amjad","doi":"10.1590/1806-9282.20231418","DOIUrl":"https://doi.org/10.1590/1806-9282.20231418","url":null,"abstract":"","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"98 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140676770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanna Gabriela da Cruz Alfaro, S. C. G. Gomes Junior, R. Sá, E. Araujo Júnior
{"title":"Analysis of Down syndrome newborn outcomes in three neonatal intensive care units in Rio de Janeiro, Brazil","authors":"Hanna Gabriela da Cruz Alfaro, S. C. G. Gomes Junior, R. Sá, E. Araujo Júnior","doi":"10.1590/1806-9282.20231186","DOIUrl":"https://doi.org/10.1590/1806-9282.20231186","url":null,"abstract":"SUMMARY OBJECTIVE: The aim of this study was to analyze the outcomes of newborns with Down syndrome admitted to three neonatal intensive care units in the city of Rio de Janeiro, Brazil. METHODS: A retrospective cohort study was conducted by analyzing the medical records between 2014 and 2018 of newborns with Down syndrome admitted to three neonatal intensive care units. The following variables were analyzed: maternal and perinatal data, neonatal malformations, neonatal intensive care unit intercurrences, and outcomes. RESULTS: A total of 119 newborns with Down syndrome were recruited, and 112 were selected for analysis. The most common maternal age group was >35 years (72.07%), the most common type of delivery was cesarean section (83.93%), and the majority of cases were male (53.57%). The most common reasons for neonatal intensive care unit hospitalization were congenital heart disease (57.66%) and prematurity (23.21%). The most common form of feeding was a combination of human milk and formula (83.93%). The second most common malformation was duodenal atresia (9.82%). The most common complications during neonatal intensive care unit hospitalization were transient tachypnea of the newborn (63.39%), hypoglycemia (18.75%), pulmonary hypertension (7.14%), and sepsis (7.14%). The mean length of stay in the neonatal intensive care unit was 27 days. The most common outcome was discharge (82.14%). Furthermore, 12.50% of newborns were transferred to an external neonatal intensive care unit, and 6% died. CONCLUSION: Newborns with Down syndrome are more likely to be admitted to the neonatal intensive care unit, and the length of hospital stay is longer due to complications related to congenital malformations common to this syndrome and prematurity.","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"21 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140674076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. S. Gunkaya, A. Tekin, Ayşegül Bestel, Oğuz Arslan, Fatih Şahin, B. D. Taymur, N. Tuğ
{"title":"Is polycystic ovary syndrome a risk factor for depression and anxiety?: a cross-sectional study","authors":"O. S. Gunkaya, A. Tekin, Ayşegül Bestel, Oğuz Arslan, Fatih Şahin, B. D. Taymur, N. Tuğ","doi":"10.1590/1806-9282.20230918","DOIUrl":"https://doi.org/10.1590/1806-9282.20230918","url":null,"abstract":"SUMMARY OBJECTIVE: The objective of this study was to learn more about the prevalence and pathophysiology of depression and anxiety that may be caused by polycystic ovary syndrome and to make plans for taking necessary precautions for this vulnerable group. METHODS: This case-control study was conducted between January 2022 and October 2022. A total of 120 women with polycystic ovary syndrome and 143 controls were included in the study. All healthy volunteers and women with polycystic ovary syndrome were evaluated using self-administered questionnaires and physical examination. Anthropometric data such as weight and height and laboratory value were documented. RESULTS: There was no significant difference between the groups in terms of demographic characteristics. When the Hospital Anxiety and Depression Scale scores of both groups were compared, both depression and anxiety scores were found to be significantly higher in women with polycystic ovary syndrome compared with the control group (OR: 3.319, 95%CI, 1.563–7.047, p<0.001 and OR: 3.238, 95%CI, 1.659–6.315, p<0.001). In the Hospital Anxiety and Depression Scale questionnaire, the rate of irregular menstruation and Ferriman-Gallwey score were statistically significant in women with polycystic ovary syndrome with high depression and anxiety scores. While serum LH levels and LH/FSH ratios were significantly different in women with polycystic ovary syndrome with high depression scores, serum LH, LH:FSH ratios, and serum total testosterone levels were found significant in women with polycystic ovary syndrome with high anxiety scores. CONCLUSION: It is clear that depression and anxiety are more common in patients with polycystic ovary syndrome than in healthy women. Our findings support previous recommendations regarding routine screening for depression and anxiety in this population.","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"53 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140672641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ozlem Sogukpinar, U. Akturk, M. O. Akbay, Erdal Tatlidil, Dilek Ernam
{"title":"Diagnostic value of transthoracic needle biopsy in lung tumors","authors":"Ozlem Sogukpinar, U. Akturk, M. O. Akbay, Erdal Tatlidil, Dilek Ernam","doi":"10.1590/1806-9282.20231082","DOIUrl":"https://doi.org/10.1590/1806-9282.20231082","url":null,"abstract":"SUMMARY OBJECTIVE: Thoracic ultrasonography is widely used in imaging peripheral lesions and invasive interventional procedures. The aim of this study was to assess the diagnostic value of thoracic ultrasonography-guided transthoracic needle aspiration biopsy and the factors affecting the diagnosis of peripheral tumoral lung lesions. METHODS: The lesion size, biopsy needle type, number of blocks, complications, and pathology results were compared in 83 patients between January 2015 and July 2018. The cases with pathological non-diagnosis and definite pathological diagnosis were determined. For the assessment of the factors affecting diagnosis, the size of the lesions and the biopsy needle type were evaluated. Biopsy preparations containing non-diagnostic atypical cells were referred to a cytopathologist. The effect of the cytopathological examination on the diagnosis was also evaluated. RESULTS: Pathological diagnosis was made in 66.3% of the cases; cell type could not be determined in 22.9% of the cases, and they were referred to a cytopathologist. After the cytopathologist's examination, the diagnosis rate increased to 80.7%. Diagnosis rates were higher when using tru-cut than Chiba and higher in cases with tumor size >2 cm than smaller. CONCLUSION: Thoracic ultrasonography-guided transthoracic needle aspiration biopsy is a preferred approach to the diagnosis of peripheral tumoral lung lesions, given its high diagnostic rate, in addition to being cheap, highly suitable for bedside use, and safe, and the lack of radiation exposure.","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"1 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140673640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Okan Sancer, Uğur Şahin, E. S. Çetin, Muhammet Yusuf Tepebaşı, Yasemin Cezaroğlu, Göksel Bilir, Sibel Yünlü, Ahmet Koca
{"title":"Effect of Laurus nobilis on bacteria and human transforming growth factor-β1","authors":"Okan Sancer, Uğur Şahin, E. S. Çetin, Muhammet Yusuf Tepebaşı, Yasemin Cezaroğlu, Göksel Bilir, Sibel Yünlü, Ahmet Koca","doi":"10.1590/1806-9282.20230683","DOIUrl":"https://doi.org/10.1590/1806-9282.20230683","url":null,"abstract":"SUMMARY OBJECTIVE: In this study, we aimed to determine the phenolic compounds, the antibacterial activity of extract from Laurus nobilis leaves, and its possible effect on transforming growth factor-β1 expression level in peripheral blood mononuclear cells. METHODS: The phenolic components of Laurus nobilis were identified by the high-performance liquid chromatography method. The antibacterial activity of this extract was determined by disk diffusion and broth microdilution methods. The transforming growth factor-β1 expression was analyzed using the RT-qPCR method. RESULTS: Epicatechin was found in the highest amount and o-coumaric acid in the lowest amount. The half-maximal inhibitory concentration (IC50) was determined to be 55.17 μg/mL. The zones of inhibition and minimum inhibitory concentration for Staphylococcus aureus, Enterococcus faecalis, and Klebsiella pneumoniae were 15, 14, and 8 mm and 125, 250, and 1000 μg/mL, respectively. The change in transforming growth factor-β1 expression levels was found to be statistically significant compared with the control groups (p<0.0001). CONCLUSION: Laurus nobilis extract was found to be effective against bacteria and altered the expression level of transforming growth factor-β1 in peripheral blood mononuclear cells.","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140673932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Araujo, L. G. O. Brito, Andrea A Marques, Marcela Bardin, C. Juliato
{"title":"Mobile app for pelvic floor muscle training for urinary incontinence during the coronavirus disease 2019 pandemic: clinical trial","authors":"C. Araujo, L. G. O. Brito, Andrea A Marques, Marcela Bardin, C. Juliato","doi":"10.1590/1806-9282.20231073","DOIUrl":"https://doi.org/10.1590/1806-9282.20231073","url":null,"abstract":"SUMMARY OBJECTIVE: The objective of this study was to evaluate the effects of home-based pelvic floor muscle training in women with urinary incontinence, addressing the difficulties arising from social isolation due to the coronavirus disease 2019 pandemic by utilizing a specialized mobile app. METHODS: This randomized, single-group clinical trial aimed to assess the efficacy of pelvic floor muscle training guided by a mobile app (Diario Saúde) in women with stress urinary incontinence. Participants were instructed via telephone to engage in pelvic floor muscle training exercises twice a day for 30 days. Pre- and post-treatment, participants completed validated questionnaires regarding urinary symptoms and quality of life through telephone interviews. Additionally, treatment adherence was evaluated. RESULTS: A total of 156 women were enrolled in the study, with a mean age of 49.3±14.2 years. Significant improvements in urinary incontinence symptoms and quality of life were observed following pelvic floor muscle training guided by the mobile app (p<0.001). Notably, 74.3% of the participants reported performing the exercises with appropriate frequency. Of the participants, 62% reported either complete or substantial improvement in urinary symptoms post-treatment. CONCLUSION: This study revealed notable enhancements in stress urinary incontinence, urinary storage, and overall quality of life subsequent to pelvic floor muscle training guided by a mobile app, particularly during the coronavirus disease 2019 pandemic. The mobile app demonstrated robust acceptance and adherence among women experiencing urinary incontinence.","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"85 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140676975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuela Leitão de Vasconcelos, Divany Guedes Pereira da Cunha, Giorvan Ânderson dos Santos Alves, Tatiana Carneiro da Cunha Almeida Santos, Luiz Medeiros de Araujo Lima-Filho, Karinna Veríssimo Meira Taveira, C. Araújo, L. Pernambuco
{"title":"Management of sialorrhea in children: a systematic review","authors":"Manuela Leitão de Vasconcelos, Divany Guedes Pereira da Cunha, Giorvan Ânderson dos Santos Alves, Tatiana Carneiro da Cunha Almeida Santos, Luiz Medeiros de Araujo Lima-Filho, Karinna Veríssimo Meira Taveira, C. Araújo, L. Pernambuco","doi":"10.1590/1806-9282.20230971","DOIUrl":"https://doi.org/10.1590/1806-9282.20230971","url":null,"abstract":"","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"16 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140674238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of aging anxiety in middle-aged women","authors":"Neşe Kıskaç, Mahruk Rashidi, Muharrem Kıskaç","doi":"10.1590/1806-9282.20231220","DOIUrl":"https://doi.org/10.1590/1806-9282.20231220","url":null,"abstract":"SUMMARY OBJECTIVE: The aim of this study was to determine the state of aging anxiety in middle-aged women. METHODS: The study was collected from women between the ages of 40 and 59 years by an online survey method. While collecting the data of the participants, the women's personal characteristics diagnostic form and the Aging Anxiety Scale for Middle-Aged Women were used. The data were analyzed with the SPSS 26 statistical software. RESULTS: The aging anxiety of the women was found to be moderate (53.05±16.26). A significant correlation was found between women's menopausal status, household income, education level, and total score of aging anxiety (p<0.05). CONCLUSION: In addition to working outside the home, women are also burdened with duties inside the home. To improve their quality of life, women need to share many of the tasks imposed on them with other family members. To reduce the anxiety experienced by women during the climacteric period, it is recommended to provide psychosocial support to women and consider this issue in health policies. Healthcare professionals, especially nurses, have important duties to reduce anxiety and stress, which constitute the basis of many chronic diseases. It is recommended that nurses, who are health ambassadors, direct women with anxiety to psychological support services through screenings they will conduct for women during this period.","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"54 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140675764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Factors influencing neonatal outcomes in twin pregnancies undergoing cesarean section: a cross-sectional study\"","authors":"Hua Tian, Jinjin Liu","doi":"10.1590/1806-9282.20231309","DOIUrl":"https://doi.org/10.1590/1806-9282.20231309","url":null,"abstract":"We read with great interest the recent study 1 on neonatal outcomes in twin pregnancies undergoing cesarean section. The study’s conclusion regarding the factors strongly associated with poor neonatal outcomes in twins delivered by cesarean section is particularly noteworthy. The findings highlight the significant impact of general anesthesia, emergency surgery, early gestational weeks, and birth weight below the 3rd weight percentile on neonatal well-being. Understanding these influential factors in twin pregnancies undergoing cesarean section is crucial for clinicians and healthcare providers. It not only aids in risk assessment but also allows for better-informed decision-making when planning and performing cesarean sections for twin pregnancies. The study’s 1 emphasis on these specific factors provides valuable insights that can contribute to improving the overall care and outcomes for both mothers and their neonates in twin pregnancies. However, we believe that the following aspects require further clarification.","PeriodicalId":447105,"journal":{"name":"Revista da Associação Médica Brasileira","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140674302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}