Trends in Anaesthesia and Critical Care最新文献

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Challenges in laryngeal mask ventilation: Case of a vocal cord polyp
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2025-02-01 DOI: 10.1016/j.tacc.2025.101517
Sangrà-Puig M, Tena B, Bergé R, Barranco de Santiago A, Garavito L, Magaldi M
{"title":"Challenges in laryngeal mask ventilation: Case of a vocal cord polyp","authors":"Sangrà-Puig M,&nbsp;Tena B,&nbsp;Bergé R,&nbsp;Barranco de Santiago A,&nbsp;Garavito L,&nbsp;Magaldi M","doi":"10.1016/j.tacc.2025.101517","DOIUrl":"10.1016/j.tacc.2025.101517","url":null,"abstract":"<div><div>The most frequent causes of airway obstruction during the use of laryngeal mask airway (LMA) devices are related to a superficial plane of anesthesia or misposition. However, uncommon causes must also be considered. This case report presents a patient scheduled for elective surgery, encountering unexpected difficulties during airway management due to a previously undiagnosed giant vocal cord polyp. The steps for managing a difficult airway were followed correctly finally leading to awakening the patient to prevent a potentially dangerous “can't intubate, can't ventilate” scenario.</div><div>This case emphasizes the importance of thorough preoperative airway assessment, early recognition of airway difficulties and the strategic use of awake intubation techniques in complex airway management situations.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"60 ","pages":"Article 101517"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143153845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incision depth in surgical airway management using computed tomography of the neck to minimize complications
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2025-02-01 DOI: 10.1016/j.tacc.2025.101518
Jungwan Yoo , Sungwoo Choi , Sangun Nah , Young Soon Cho , Jae wook Lee , Sangsoo Han
{"title":"Incision depth in surgical airway management using computed tomography of the neck to minimize complications","authors":"Jungwan Yoo ,&nbsp;Sungwoo Choi ,&nbsp;Sangun Nah ,&nbsp;Young Soon Cho ,&nbsp;Jae wook Lee ,&nbsp;Sangsoo Han","doi":"10.1016/j.tacc.2025.101518","DOIUrl":"10.1016/j.tacc.2025.101518","url":null,"abstract":"<div><h3>Background</h3><div>Swift and accurate airway management is crucial in the emergency department. Failure to secure the airway in hypoxic individuals can lead to severe outcomes, including brain damage or death. When a difficult airway is anticipated or intubation fails, alternatives such as cricothyroidotomy or tracheostomy must be considered, taking into account patient characteristics.</div></div><div><h3>Aim</h3><div>Analysis of the relationship between patient's characteristics and the depth of the cricothyroid membrane (CTM) and tracheostomy sites (TSs).</div></div><div><h3>Methods</h3><div>We conducted a retrospective cross-sectional study of patients who underwent neck CT scans in the emergency department and 475 patients were included. The shortest distance from the skin to the innermost surface of the CTM (CTM depth) was measured in the sagittal view of the CT. For tracheostomy, depths were measured from the skin at the cricoid cartilage (1–2 cm below) to the membranes between the second and third tracheal rings (TS1) and between the third and fourth rings (TS2). Patient characteristics, including age, sex, height, and weight, were recorded to assess correlations with depth through multiple linear regression analysis.</div></div><div><h3>Results</h3><div>The average CTM depth was 10.87 ± 3.93 mm, while the depths at TS1 and TS2 were 12.38 ± 4.72 mm and 14.75 ± 6.30 mm, respectively. Significant correlations were found between patient age, body mass index, sex, and the depths of the CTM and TSs 1 and 2. Older age and increased obesity were associated with greater depths, particularly at TS2. Notably, females exhibited greater depths at CTM and TS1 than males, with no significant differences at TS2.</div></div><div><h3>Conclusions</h3><div>These findings offer valuable insights for anticipating incision depth during urgent surgical airway procedures, potentially minimizing complications and improving treatment outcomes.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"60 ","pages":"Article 101518"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143153848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in the development of invasive ventilator liberation
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2025-02-01 DOI: 10.1016/j.tacc.2025.101521
Hui Liu , Xiaoyi Liu , Jiangxia Pan , Rui Zhou , Hui Ran , Lili Chen
{"title":"Recent advances in the development of invasive ventilator liberation","authors":"Hui Liu ,&nbsp;Xiaoyi Liu ,&nbsp;Jiangxia Pan ,&nbsp;Rui Zhou ,&nbsp;Hui Ran ,&nbsp;Lili Chen","doi":"10.1016/j.tacc.2025.101521","DOIUrl":"10.1016/j.tacc.2025.101521","url":null,"abstract":"<div><div>Invasive ventilation is a critical respiratory support technology in the intensive care unit (ICU). Increasing evidence suggests that early liberation from invasive ventilation can benefit patients. However, further research is needed to establish optimal criteria for invasive ventilator liberation programs, including the ideal screening frequency, appropriate techniques and duration of spontaneous breathing trials (SBT), evaluation of airway extubation readiness, and decision-making regarding extubation. The management of the invasive ventilator liberation process should encompass feasibility screening for SBTs, conducting SBTs, evaluating SBT outcomes, assessing airway extubation readiness, performing extubation itself, identifying high-risk factors associated with weaning failure, and developing clinical strategies. Additionally, a patient-centered assessment of the risks and consequences of extubation failure may serve as crucial measures to enhance the success rate of invasive ventilator liberation. Therefore, we conduct a detailed review of the related studies on invasive mechanical ventilation weaning to determine the best invasive ventilator liberation strategy.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"60 ","pages":"Article 101521"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143153847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of sonographic hyomental distance ratio and thyromental height as predictors of difficult intubation
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2025-02-01 DOI: 10.1016/j.tacc.2025.101520
Parul Sood , Richa Saroa , Sanjeev Palta , Puja Saxena , Ravneet Kaur Gill
{"title":"Comparison of sonographic hyomental distance ratio and thyromental height as predictors of difficult intubation","authors":"Parul Sood ,&nbsp;Richa Saroa ,&nbsp;Sanjeev Palta ,&nbsp;Puja Saxena ,&nbsp;Ravneet Kaur Gill","doi":"10.1016/j.tacc.2025.101520","DOIUrl":"10.1016/j.tacc.2025.101520","url":null,"abstract":"<div><h3>Background</h3><div>Preoperative airway assessment has always been dynamic to quantify a single parameter that identifies difficult airway reliably and therefore newer modalities are introduced, researched and compared amongst themselves. Thyromental height (TMH) and hyomental distance ratio (HMDR) have been recently developed and validated as good diagnostic tools for difficult airway prediction. However, they have not been compared with respect to each other as to define the superiority amongst the two and thus present trial was designed to assess the same.</div></div><div><h3>Method</h3><div>400 patients &gt;18 years of age undergoing elective surgery under general anaesthesia were enrolled in the study. In addition to the standard airway parameter assessment, preoperative TMH and sonographic HMDR was also recorded which was correlated with Cormack Lehane (CL) grade and percentage of glottic opening (POGO) score of laryngoscopy to grade a difficult airway.</div></div><div><h3>Results</h3><div>HMDR (83 %) was found to be more accurate in predicting difficult intubation than TMH (56.5 %). Though the sensitivity of TMH (70.83 %) and HMDR (68 %) were comparable, HMDR (84.66 %) was found to be more specific than TMH (54.83 %) for a difficult airway prediction. The cut off values for HMDR and TMH for predicting difficult intubation, derived from the present study from the ROC curves and AUC was found to be 1.26 and 5.05 cm respectively.</div></div><div><h3>Conclusions</h3><div>HMDR outstrips TMH with a good sensitivity and specificity for difficult airway prediction. In conclusion, we recommend the use of sonographically derived HMDR as a reliable airway assessment parameter to predict a difficult airway.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"60 ","pages":"Article 101520"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video laryngoscopy for obstetric airway management: A narrative review
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2025-02-01 DOI: 10.1016/j.tacc.2025.101522
Fernanda S.L. Oliveira, Fabricio B. Zasso, Kevin S. Chen, Kong Eric You-Ten, Naveed Siddiqui
{"title":"Video laryngoscopy for obstetric airway management: A narrative review","authors":"Fernanda S.L. Oliveira,&nbsp;Fabricio B. Zasso,&nbsp;Kevin S. Chen,&nbsp;Kong Eric You-Ten,&nbsp;Naveed Siddiqui","doi":"10.1016/j.tacc.2025.101522","DOIUrl":"10.1016/j.tacc.2025.101522","url":null,"abstract":"<div><div>The obstetric population has an increased risk of difficult airways due to changes, with a mortality rate of 1 death per 90 failed intubations. Recently guidelines for difficult airway management have recognized and recommended video laryngoscopy devices in difficult airway cases. Although there has been a substantial number of publications on video laryngoscopy, there is a lack of literature to help establish its use for managing obstetric airways. Therefore, we conducted a narrative review to evaluate the performance and efficacy of video laryngoscopy in obstetric patients. A literature review was performed on papers published until November 2024, studying adult patients who underwent obstetric procedures under general anesthesia. Improved glottis visualization, increased success rate in patients with predicted difficult airways, and rescue of a failed direct laryngoscopy attempt are advantages of video laryngoscopy. There are conflicting results regarding video laryngoscopy being superior to direct laryngoscopy regarding first-attempt success and time to intubation. Additionally, we discussed different types of video laryngoscope blades and video laryngoscopy with training in the obstetric population. Our review's findings are consistent with the current guidelines that recommend video laryngoscopes should be available for every obstetric general anesthesia, summed to the need for larger studies in this population.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"60 ","pages":"Article 101522"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying and analyzing extremely productive authors in intensive care medicine: A scientometric analysis
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2025-02-01 DOI: 10.1016/j.tacc.2024.101515
Francesco Zarantonello , Nicolò Sella , Alessandro De Cassai , Giulia Aviani Fulvio , Annalisa Boscolo , Tommaso Pettenuzzo , Giulia Mormando , Paolo Navalesi
{"title":"Identifying and analyzing extremely productive authors in intensive care medicine: A scientometric analysis","authors":"Francesco Zarantonello ,&nbsp;Nicolò Sella ,&nbsp;Alessandro De Cassai ,&nbsp;Giulia Aviani Fulvio ,&nbsp;Annalisa Boscolo ,&nbsp;Tommaso Pettenuzzo ,&nbsp;Giulia Mormando ,&nbsp;Paolo Navalesi","doi":"10.1016/j.tacc.2024.101515","DOIUrl":"10.1016/j.tacc.2024.101515","url":null,"abstract":"<div><h3>Introduction</h3><div>Clinical progress relies heavily on research, however, recent years have seen distortions in this process due to the “publish or perish” model. This model is further amplified by team science, leading to inflated author counts and metrics. Recently the rise of hyperprolific (HA) and almost hyperprolific (AHA) authors has been highlighted in the global literature scenario, but data on intensive care medicine (ICM) is lacking. This study aims to investigate HA and AHA authors in ICM and the impact of COVID-19 pandemic on publication rates.</div></div><div><h3>Material and methods</h3><div>We identified authors publishing in ICM journals indexed by Scopus from 2019 to 2023, retrieving their Scopus IDs, publication details, and gender. HA were defined as authors who published at least 73 articles per year, while AHA as authors who published more than 60. The effect of COVID-19 literature was assessed by excluding COVID-related articles from the dataset.</div></div><div><h3>Results</h3><div>We identified 42860 articles in ICM journals, involving 186150 unique authors with a median of 5 publications per author. Only 248 (0.1 %) were extremely productive, with 131 being hyperprolific (HA). Removing COVID-19 papers significantly reduced HA and AHA counts by up to 40 %. Extremely productive authors were predominantly male (91.5 %) and globally distributed, primarily from Europe, Asia, and the Americas.</div></div><div><h3>Conclusions</h3><div>Hyperprolific authors in ICM represent a very small minority. These authors are typically related to ICM, male, senior researchers with a global distribution, who publish high-quality research through a significant research network.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"60 ","pages":"Article 101515"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143153846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Narrative review of psilocybin, an important psychoactive substance with potential peri-anesthetic implications
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2024-12-01 DOI: 10.1016/j.tacc.2024.101514
George L. Tewfik , Adejuyigbe Adaralegbe , Sangel Gomez , Rania Aziz , Faraz Chaudhry , Daniel Rodriguez-Correa , Dorisanne O. Adaralegbe
{"title":"Narrative review of psilocybin, an important psychoactive substance with potential peri-anesthetic implications","authors":"George L. Tewfik ,&nbsp;Adejuyigbe Adaralegbe ,&nbsp;Sangel Gomez ,&nbsp;Rania Aziz ,&nbsp;Faraz Chaudhry ,&nbsp;Daniel Rodriguez-Correa ,&nbsp;Dorisanne O. Adaralegbe","doi":"10.1016/j.tacc.2024.101514","DOIUrl":"10.1016/j.tacc.2024.101514","url":null,"abstract":"<div><div>Psilocybin is a psychedelic substance with history of use for religious, medicinal and hallucinogenic purposes. The purpose of this review is to assess its past use, and its role both broadly in medicine and specifically in anesthesiology. Studies have shown benefits for chronic pain management, demonstrating utility in conditions including headaches and fibromyalgia, and psychiatric disturbances such as depression and anxiety. It has a high safety prof0ile, with a large disparity between a physiologic dose and that required to cause overdose symptoms. Its structure allows it to function as a serotonin receptor agonist, affecting the wiring of the brain and leading to possible anti-inflammatory effects. Perioperative management by anesthesia professionals should include a thorough pre-anesthetic exam to assess for usage and associated symptoms, as well as targeted testing. Intoxication requires supportive care, while overdose and withdrawal symptoms may require management of one's airway, circulation or appropriate medication. Patients should be monitored through the perioperative period, for psychologic symptoms that may necessitate modifications to the physical environment or pharmaceutical interventions. Rates of usage of psilocybin may increase if removed from Schedule I by the FDA based upon therapeutic uses for chronic pain and psychological disorders, amongst other conditions.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"59 ","pages":"Article 101514"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the lipsense device for reducing oral dryness in patients undergoing general anesthesia for elective daycare surgeries
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2024-12-01 DOI: 10.1016/j.tacc.2024.101513
Alisha Goel, Vikas Saini, Rashi Sarna, Sameer Sethi, Summit Bloria, Waseem Ahmad Khan, Rajeev Chauhan
{"title":"Evaluating the lipsense device for reducing oral dryness in patients undergoing general anesthesia for elective daycare surgeries","authors":"Alisha Goel,&nbsp;Vikas Saini,&nbsp;Rashi Sarna,&nbsp;Sameer Sethi,&nbsp;Summit Bloria,&nbsp;Waseem Ahmad Khan,&nbsp;Rajeev Chauhan","doi":"10.1016/j.tacc.2024.101513","DOIUrl":"10.1016/j.tacc.2024.101513","url":null,"abstract":"<div><h3>Background and aims</h3><div>Postoperative thirst and oral dryness after general anesthesia is a well-known concern encountered in the post anesthesia care unit; equally distressing for the patient and the clinician. The Lipsense device (Coolsense ltd, Tel Aviv, Israel) is a novel device which allows controlled delivery of water to relieve thirst and oral dryness. We hypothesized lipsesne will be effective to decrease thirst and oral dryness and thus improve overall patient and care giver satisfaction.</div></div><div><h3>Method</h3><div>This was a prospective randomized controlled study conducted in 120 adult patients, equally divided into 3 groups receiving Lipsense, wet gauge and no intervention; undergoing daycare surgeries under general anesthesia and complaining of postoperative thirst. Numerical rating scores of thirst and oral dryness were measured at 0,1,2,3 h of postoperative period by an independent observer.</div></div><div><h3>Results</h3><div>The mean difference in intensity scores for thirst and oral dryness from baseline till the end of 3 h was greater in the Lipsense group (4.12 and 4.26 respectively) than in the wet gauge group (2.92 and 2.82). Lipsense resulted in a greater reduction, i.e. 72 % as compared to our hypothesis of 35 % reduction. Wet gauge resulted in a 46 % reduction in thirst intensity.</div></div><div><h3>Conclusion</h3><div>Lipsense is an effective device to reduce postoperative thirst and oral dryness with minimal side effects in comparison to wet gauge or no intervention in patients after general anesthesia.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"59 ","pages":"Article 101513"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the potential of artificial intelligence in airway management
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2024-12-01 DOI: 10.1016/j.tacc.2024.101512
Luigi La Via , Antonino Maniaci , David Gage , Giuseppe Cuttone , Giovanni Misseri , Mario Lentini , Daniele Salvatore Paternò , Federico Pappalardo , Massimiliano Sorbello
{"title":"Exploring the potential of artificial intelligence in airway management","authors":"Luigi La Via ,&nbsp;Antonino Maniaci ,&nbsp;David Gage ,&nbsp;Giuseppe Cuttone ,&nbsp;Giovanni Misseri ,&nbsp;Mario Lentini ,&nbsp;Daniele Salvatore Paternò ,&nbsp;Federico Pappalardo ,&nbsp;Massimiliano Sorbello","doi":"10.1016/j.tacc.2024.101512","DOIUrl":"10.1016/j.tacc.2024.101512","url":null,"abstract":"<div><div>This review examines the integration of Artificial Intelligence (AI) language models, particularly Chat GPT, in airway management. It explores AI's potential applications in education, clinical decision support, patient communication, and research, as well as its integration with existing medical technologies. The review highlights AI's benefits, including rapid access to current information, care standardization, and potential improvements in patient outcomes. However, it also addresses limitations and ethical considerations such as data security, algorithm bias, and the risk of over-reliance on AI systems. Looking forward, the review discusses AI's potential to revolutionize airway management through predictive analytics, augmented reality, and personalized learning platforms, while acknowledging implementation challenges. The broader implications of AI in healthcare are explored, including its impact on learning, innovation, and the balance between error-free decision-making and human creativity. The review concludes that while AI shows great promise in enhancing airway management, its implementation requires careful consideration of ethical implications and ongoing research. The future of AI in this field lies in its judicious use alongside skilled clinical judgment, potentially leading to significant improvements in patient care and outcomes.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"59 ","pages":"Article 101512"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the hemodynamic responses to laryngoscopy and intubation on induction with etomidate, propofol-ketamine or propofol-etomidate: A randomized trial
IF 1.4
Trends in Anaesthesia and Critical Care Pub Date : 2024-12-01 DOI: 10.1016/j.tacc.2024.101504
Malvika Gupta, Anju R. Bhalotra, Shweta Dhiman, Rahil Singh
{"title":"Comparison of the hemodynamic responses to laryngoscopy and intubation on induction with etomidate, propofol-ketamine or propofol-etomidate: A randomized trial","authors":"Malvika Gupta,&nbsp;Anju R. Bhalotra,&nbsp;Shweta Dhiman,&nbsp;Rahil Singh","doi":"10.1016/j.tacc.2024.101504","DOIUrl":"10.1016/j.tacc.2024.101504","url":null,"abstract":"<div><h3>Background</h3><div>Haemodynamic stability is desirable during induction of anaesthesia. Intravenous induction agents have differing haemodynamic effects. We compared the haemodynamic effects of combinations of propofol-ketamine (PK) and propofol-etomidate (PE) with etomidate alone during induction of anaesthesia and laryngoscopy and endotracheal intubation.</div></div><div><h3>Material and methods</h3><div>This randomized controlled study was conducted on 90 ASA I patients aged 18–50 years undergoing elective surgery requiring endotracheal intubation under general anaesthesia who were randomly allocated to either Group E (Etomidate 0.3 mg/kg), Group PE (Propofol 1 mg/kg + Etomidate 0.15 mg/kg) or Group PK (Propofol 1 mg/kg + Ketamine 1 mg/kg). Mean arterial pressure (MAP), systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and bispectral index (BIS) values were compared at different time points.</div></div><div><h3>Results</h3><div>After anaesthesia induction, the percentage fall in mean, systolic and diastolic blood pressure was least in the PK group. Laryngoscopy and intubation led to a rise in haemodynamic parameters in all groups. The mean, systolic and diastolic blood pressures were significantly higher in Group E at 1 min after intubation as compared to the other two groups. With etomidate, the fall in MAP prior to intubation was greater as was the intubation response despite lower BIS values. No correlation was found between haemodynamic response and BIS values attained after intubation.</div></div><div><h3>Conclusions</h3><div>Combinations of propofol with ketamine and etomidate in the selected doses were found to be superior to etomidate alone with respect to haemodynamic stability. Co-induction with propofol and ketamine maybe preferred when haemodynamic stability is required. Ketamine has the advantage of providing potent analgesia in this dose.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"59 ","pages":"Article 101504"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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