{"title":"灌注指数作为麻醉儿童尾侧硬膜外阻滞成功的指标:一项观察性研究","authors":"A.R. Ajay Saran, Anju R. Bhalotra","doi":"10.1016/j.tacc.2025.101550","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>It is often difficult to assess the success of caudal epidural block in children under general anaesthesia. We hypothesized that increase in lower limb perfusion index after caudal anaesthesia indicates a successful block and aimed to study changes in lower limb perfusion index after caudal block in children under general anaesthesia.</div></div><div><h3>Methods</h3><div>This prospective observational study was conducted in children aged 2–12 years. The primary outcome was changes in lower limb perfusion index for 20 min after caudal block. Secondary outcomes included upper limb perfusion index at the same times, differences in lower and upper limb perfusion index, haemodynamic parameters and the correlation of perfusion index with heart rate and blood pressure.</div></div><div><h3>Results</h3><div>After caudal block, lower limb perfusion index increased within 1 min (31.28 %), was 100 % higher at 5 min and reached a maximum (153.18 %) increase at 15 min. The maximum increase in upper limb perfusion index was 35.13 %. There was a fall in heart rate (8.79 %), systolic blood pressure (8.77 %), diastolic blood pressure (14.16) and mean arterial pressure (11.43 %) which were maximum at 20 min. We found a positive correlation, r = 0.97, p = .001, between perfusion index and heart rate and perfusion index and diastolic blood pressure, r = 0.82, p = .043.</div></div><div><h3>Conclusion</h3><div>There were significant and immediate increases in lower limb perfusion index after successful caudal block. Haemodynamic changes were less marked and delayed. Perfusion index was found to be an objective, sensitive and early indicator of successful caudal block in children under general anaesthesia.</div></div>","PeriodicalId":44534,"journal":{"name":"Trends in Anaesthesia and Critical Care","volume":"62 ","pages":"Article 101550"},"PeriodicalIF":0.7000,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Perfusion index as an indicator of successful caudal epidural block in anaesthestized children: an observational study\",\"authors\":\"A.R. Ajay Saran, Anju R. Bhalotra\",\"doi\":\"10.1016/j.tacc.2025.101550\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><div>It is often difficult to assess the success of caudal epidural block in children under general anaesthesia. We hypothesized that increase in lower limb perfusion index after caudal anaesthesia indicates a successful block and aimed to study changes in lower limb perfusion index after caudal block in children under general anaesthesia.</div></div><div><h3>Methods</h3><div>This prospective observational study was conducted in children aged 2–12 years. The primary outcome was changes in lower limb perfusion index for 20 min after caudal block. Secondary outcomes included upper limb perfusion index at the same times, differences in lower and upper limb perfusion index, haemodynamic parameters and the correlation of perfusion index with heart rate and blood pressure.</div></div><div><h3>Results</h3><div>After caudal block, lower limb perfusion index increased within 1 min (31.28 %), was 100 % higher at 5 min and reached a maximum (153.18 %) increase at 15 min. The maximum increase in upper limb perfusion index was 35.13 %. There was a fall in heart rate (8.79 %), systolic blood pressure (8.77 %), diastolic blood pressure (14.16) and mean arterial pressure (11.43 %) which were maximum at 20 min. We found a positive correlation, r = 0.97, p = .001, between perfusion index and heart rate and perfusion index and diastolic blood pressure, r = 0.82, p = .043.</div></div><div><h3>Conclusion</h3><div>There were significant and immediate increases in lower limb perfusion index after successful caudal block. Haemodynamic changes were less marked and delayed. Perfusion index was found to be an objective, sensitive and early indicator of successful caudal block in children under general anaesthesia.</div></div>\",\"PeriodicalId\":44534,\"journal\":{\"name\":\"Trends in Anaesthesia and Critical Care\",\"volume\":\"62 \",\"pages\":\"Article 101550\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Anaesthesia and Critical Care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2210844025000346\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Anaesthesia and Critical Care","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210844025000346","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的:在全麻状态下对儿童进行尾侧硬膜外阻滞的成功率往往难以评估。我们假设尾侧麻醉后下肢灌注指数的增加表明阻滞成功,旨在研究全麻下儿童尾侧麻醉后下肢灌注指数的变化。方法本前瞻性观察研究在2-12岁儿童中进行。主要观察终点是尾侧阻滞后20分钟下肢灌注指数的变化。次要结局包括同期上肢灌注指数、上下肢灌注指数差异、血流动力学参数及灌注指数与心率、血压的相关性。结果尾侧阻滞后,下肢灌注指数在1 min内升高(31.28%),5 min时升高100%,15 min时达到最大值(153.18%),上肢灌注指数最大升高35.13%。心率(8.79%)、收缩压(8.77%)、舒张压(14.16%)、平均动脉压(11.43%)在20 min时下降幅度最大。血流灌注指数与心率、血流灌注指数与舒张压呈正相关,r = 0.97, p = 0.001, r = 0.82, p = 0.043。结论尾侧阻滞成功后,下肢灌注指数立即显著升高。血流动力学变化不明显且延迟。灌注指数是一个客观、敏感和早期的指标,成功的尾侧阻滞儿童在全身麻醉。
Perfusion index as an indicator of successful caudal epidural block in anaesthestized children: an observational study
Purpose
It is often difficult to assess the success of caudal epidural block in children under general anaesthesia. We hypothesized that increase in lower limb perfusion index after caudal anaesthesia indicates a successful block and aimed to study changes in lower limb perfusion index after caudal block in children under general anaesthesia.
Methods
This prospective observational study was conducted in children aged 2–12 years. The primary outcome was changes in lower limb perfusion index for 20 min after caudal block. Secondary outcomes included upper limb perfusion index at the same times, differences in lower and upper limb perfusion index, haemodynamic parameters and the correlation of perfusion index with heart rate and blood pressure.
Results
After caudal block, lower limb perfusion index increased within 1 min (31.28 %), was 100 % higher at 5 min and reached a maximum (153.18 %) increase at 15 min. The maximum increase in upper limb perfusion index was 35.13 %. There was a fall in heart rate (8.79 %), systolic blood pressure (8.77 %), diastolic blood pressure (14.16) and mean arterial pressure (11.43 %) which were maximum at 20 min. We found a positive correlation, r = 0.97, p = .001, between perfusion index and heart rate and perfusion index and diastolic blood pressure, r = 0.82, p = .043.
Conclusion
There were significant and immediate increases in lower limb perfusion index after successful caudal block. Haemodynamic changes were less marked and delayed. Perfusion index was found to be an objective, sensitive and early indicator of successful caudal block in children under general anaesthesia.