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Journal of Micro-Bio Robotics最新文献

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A compact targeted drug delivery mechanism for a next generation wireless capsule endoscope. 用于下一代无线胶囊内窥镜的紧凑型靶向给药机制。
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2016-01-01 Epub Date: 2016-05-13 DOI: 10.1007/s12213-016-0088-9
Stephen P Woods, Timothy G Constandinou
{"title":"A compact targeted drug delivery mechanism for a next generation wireless capsule endoscope.","authors":"Stephen P Woods, Timothy G Constandinou","doi":"10.1007/s12213-016-0088-9","DOIUrl":"10.1007/s12213-016-0088-9","url":null,"abstract":"<p><p>This paper reports a novel medication release and delivery mechanism as part of a next generation wireless capsule endoscope (WCE) for targeted drug delivery. This subsystem occupies a volume of only 17.9mm<sup>3</sup> for the purpose of delivering a 1 ml payload to a target site of interest in the small intestinal tract. An in-depth analysis of the method employed to release and deliver the medication is described and a series of experiments is presented which validates the drug delivery system. The results show that a variable pitch conical compression spring manufactured from stainless steel can deliver 0.59 N when it is fully compressed and that this would be sufficient force to deliver the onboard medication.</p>","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"11 1","pages":"19-34"},"PeriodicalIF":2.3,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35556930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of work of adhesion of biological cell (human hepatocellular carcinoma) by AFM nanoindentation. AFM纳米压痕对生物细胞(人肝癌)粘附作用的研究。
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2016-01-01 Epub Date: 2016-05-07 DOI: 10.1007/s12213-016-0089-8
Xinyao Zhu, Nan Zhang, Zuobin Wang, X Liu
{"title":"Investigation of work of adhesion of biological cell (human hepatocellular carcinoma) by <i>AFM</i> nanoindentation.","authors":"Xinyao Zhu,&nbsp;Nan Zhang,&nbsp;Zuobin Wang,&nbsp;X Liu","doi":"10.1007/s12213-016-0089-8","DOIUrl":"https://doi.org/10.1007/s12213-016-0089-8","url":null,"abstract":"<p><p>In this study, we presented an investigation of mechanical properties by AFM nanoindentation on human hepatocellular carcinoma cells treated with fullerenol for 24, 48 and 72 h. AFM nanoindentation was routinely applied to investigate the morphology and biomechanical properties of living carcinoma cells, and adhesion phenomena (negative force) were detected in the obtained force-displacement curves. Conventionally, Hertz contact model has been widely used for determination of cell elasticity, however this contact model cannot account for adhesion. Alternatively, JKR contact model, as expected for adhesion circumstance, has been applied to fit the obtained force-displacement curves. In this investigation, we have derived both the work of adhesion and the elastic modulus of biological cells (human hepatocellular carcinoma) under fullerenol treatment. The results show that the chosen JKR model can provide better fitting results than Hertz contact model. The results show that both Young's modulus and work of adhesion exhibit significant variation as the treatment time increases. The calculated mechanical properties of elastic modulus and work of adhesion can be used as an effective bio-index to evaluate the effects of fullerenol or other anticancer agents on cancer cells and thus to provide insight into cancer progression in the treatment.</p>","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"11 1","pages":"47-55"},"PeriodicalIF":2.3,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-016-0089-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35556932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Frontiers of robotic endoscopic capsules: a review. 机器人内窥镜胶囊的前沿:综述。
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2016-01-01 Epub Date: 2016-05-02 DOI: 10.1007/s12213-016-0087-x
Gastone Ciuti, R Caliò, D Camboni, L Neri, F Bianchi, A Arezzo, A Koulaouzidis, S Schostek, D Stoyanov, C M Oddo, B Magnani, A Menciassi, M Morino, M O Schurr, P Dario
{"title":"Frontiers of robotic endoscopic capsules: a review.","authors":"Gastone Ciuti,&nbsp;R Caliò,&nbsp;D Camboni,&nbsp;L Neri,&nbsp;F Bianchi,&nbsp;A Arezzo,&nbsp;A Koulaouzidis,&nbsp;S Schostek,&nbsp;D Stoyanov,&nbsp;C M Oddo,&nbsp;B Magnani,&nbsp;A Menciassi,&nbsp;M Morino,&nbsp;M O Schurr,&nbsp;P Dario","doi":"10.1007/s12213-016-0087-x","DOIUrl":"https://doi.org/10.1007/s12213-016-0087-x","url":null,"abstract":"<p><p>Digestive diseases are a major burden for society and healthcare systems, and with an aging population, the importance of their effective management will become critical. Healthcare systems worldwide already struggle to insure quality and affordability of healthcare delivery and this will be a significant challenge in the midterm future. Wireless capsule endoscopy (WCE), introduced in 2000 by Given Imaging Ltd., is an example of disruptive technology and represents an attractive alternative to traditional diagnostic techniques. WCE overcomes conventional endoscopy enabling inspection of the digestive system without discomfort or the need for sedation. Thus, it has the advantage of encouraging patients to undergo gastrointestinal (GI) tract examinations and of facilitating mass screening programmes. With the integration of further capabilities based on microrobotics, e.g. active locomotion and embedded therapeutic modules, WCE could become the key-technology for GI diagnosis and treatment. This review presents a research update on WCE and describes the state-of-the-art of current endoscopic devices with a focus on research-oriented robotic capsule endoscopes enabled by microsystem technologies. The article also presents a visionary perspective on WCE potential for screening, diagnostic and therapeutic endoscopic procedures.</p>","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"11 1","pages":"1-18"},"PeriodicalIF":2.3,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-016-0087-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35556931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 132
Influence of geometry on swimming performance of helical swimmers using DoE 几何形状对使用DoE的螺旋游泳运动员游泳性能的影响
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2015-10-29 DOI: 10.1007/s12213-015-0084-5
Tiantian Xu, G. Hwang, N. Andreff, S. Régnier
{"title":"Influence of geometry on swimming performance of helical swimmers using DoE","authors":"Tiantian Xu, G. Hwang, N. Andreff, S. Régnier","doi":"10.1007/s12213-015-0084-5","DOIUrl":"https://doi.org/10.1007/s12213-015-0084-5","url":null,"abstract":"","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"11 1","pages":"57 - 66"},"PeriodicalIF":2.3,"publicationDate":"2015-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-015-0084-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52751172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Controlling multiple microrobots: recent progress and future challenges 控制多个微型机器人:最新进展和未来挑战
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2015-10-01 DOI: 10.1007/s12213-015-0083-6
S. Chowdhury, Wuming Jing, D. Cappelleri
{"title":"Controlling multiple microrobots: recent progress and future challenges","authors":"S. Chowdhury, Wuming Jing, D. Cappelleri","doi":"10.1007/s12213-015-0083-6","DOIUrl":"https://doi.org/10.1007/s12213-015-0083-6","url":null,"abstract":"","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"10 1","pages":"1 - 11"},"PeriodicalIF":2.3,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-015-0083-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52751093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 91
Intuitive control of self-propelled microjets with haptic feedback 具有触觉反馈的自推进微型喷气机的直观控制
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2015-10-01 DOI: 10.1007/s12213-015-0082-7
C. Pacchierotti, V. Magdanz, M. Medina‐Sánchez, Oliver G. Schmidt, D. Prattichizzo, S. Misra
{"title":"Intuitive control of self-propelled microjets with haptic feedback","authors":"C. Pacchierotti, V. Magdanz, M. Medina‐Sánchez, Oliver G. Schmidt, D. Prattichizzo, S. Misra","doi":"10.1007/s12213-015-0082-7","DOIUrl":"https://doi.org/10.1007/s12213-015-0082-7","url":null,"abstract":"","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"10 1","pages":"37 - 53"},"PeriodicalIF":2.3,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-015-0082-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52750882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
MRI-based communication for untethered intelligent medical microrobots 无系绳智能医疗微型机器人的核磁共振通信
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2015-07-16 DOI: 10.1007/s12213-015-0081-8
Azadeh Sharafi, N. Olamaei, S. Martel
{"title":"MRI-based communication for untethered intelligent medical microrobots","authors":"Azadeh Sharafi, N. Olamaei, S. Martel","doi":"10.1007/s12213-015-0081-8","DOIUrl":"https://doi.org/10.1007/s12213-015-0081-8","url":null,"abstract":"","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"10 1","pages":"27 - 35"},"PeriodicalIF":2.3,"publicationDate":"2015-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-015-0081-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52750796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Microrobotic system for multi-rate measurement of bio-based fibres Z-directional bond strength 多速率测量生物基纤维z向键合强度的微型机器人系统
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2015-05-24 DOI: 10.1007/s12213-015-0080-9
S. Latifi, P. Saketi, P. Kallio
{"title":"Microrobotic system for multi-rate measurement of bio-based fibres Z-directional bond strength","authors":"S. Latifi, P. Saketi, P. Kallio","doi":"10.1007/s12213-015-0080-9","DOIUrl":"https://doi.org/10.1007/s12213-015-0080-9","url":null,"abstract":"","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"10 1","pages":"13 - 26"},"PeriodicalIF":2.3,"publicationDate":"2015-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-015-0080-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52750649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
“A versatile perching mechanism employing shape memory wires and Bio-inspired adhesives” “一种使用形状记忆线和仿生粘合剂的多功能栖息机制”
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2014-11-20 DOI: 10.1007/s12213-014-0079-7
A. Peyvandi, P. Soroushian, Jue Lu
{"title":"“A versatile perching mechanism employing shape memory wires and Bio-inspired adhesives”","authors":"A. Peyvandi, P. Soroushian, Jue Lu","doi":"10.1007/s12213-014-0079-7","DOIUrl":"https://doi.org/10.1007/s12213-014-0079-7","url":null,"abstract":"","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"10 1","pages":"55 - 67"},"PeriodicalIF":2.3,"publicationDate":"2014-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-014-0079-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52750579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Biocompatible, accurate, and fully autonomous: a sperm-driven micro-bio-robot 生物相容，精确，完全自主:精子驱动的微型生物机器人
IF 2.3
Journal of Micro-Bio Robotics Pub Date : 2014-06-13 DOI: 10.1007/s12213-014-0077-9
I. Khalil, V. Magdanz, S. Sánchez, Oliver G. Schmidt, S. Misra
{"title":"Biocompatible, accurate, and fully autonomous: a sperm-driven micro-bio-robot","authors":"I. Khalil, V. Magdanz, S. Sánchez, Oliver G. Schmidt, S. Misra","doi":"10.1007/s12213-014-0077-9","DOIUrl":"https://doi.org/10.1007/s12213-014-0077-9","url":null,"abstract":"","PeriodicalId":44493,"journal":{"name":"Journal of Micro-Bio Robotics","volume":"9 1","pages":"79 - 86"},"PeriodicalIF":2.3,"publicationDate":"2014-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12213-014-0077-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52750172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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