Ortadoğu Tıp Dergisi最新文献

Erratum: The seroprevalance of hepatitis E, hepatitis G and TTV in haemodialysis patients 血液透析患者戊型肝炎、丙型肝炎和TTV的血清患病率

Ortadoğu Tıp Dergisi Pub Date : 2020-06-28 DOI: 10.21601/ortadogutipdergisi.759248

S. Cesur, N. Yılmaz, A. Çi̇fci̇, M. Balcı, Ç. Kaya, M. Uyar, Seda Sabah Özcan, Y. Erdoğan, M. İbi̇ş

引用次数: 3

Prognostic significance of body mass index and diabetes in patients with malignant glioma 恶性胶质瘤患者体重指数与糖尿病的预后意义

Ortadoğu Tıp Dergisi Pub Date : 2020-06-11 DOI: 10.21601/ortadogutipdergisi.709170

Berrin Benli Yavuz, G. Kanyilmaz, M. Aktan

{"title":"Prognostic significance of body mass index and diabetes in patients with malignant glioma","authors":"Berrin Benli Yavuz, G. Kanyilmaz, M. Aktan","doi":"10.21601/ortadogutipdergisi.709170","DOIUrl":"https://doi.org/10.21601/ortadogutipdergisi.709170","url":null,"abstract":"Aim: We aimed to determine whether there is a relationship between body mass index (BMI) and diabetes (DM) before treatment and survival with this study. Material and Methods: The results of patients who received radiotherapy between 2010 2018 were evaluated with this retrospective study. BMI was categorized into 3 groups: normal (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), obese (≥30 kg/m2). Presence of diabetes was evaluated by considering oral antidiabetic use and file information before treatment. Patient, treatment and tumor characteristics were evaluated with descriptive statistics. Kaplan-Meirer, log-rank and coxregression analyzes were performed. P <0.05 was considered statistically significant. Results: The results of 174 cases were evaluated. Diabetes was present in 22 patients (12.6%). In univariate analyzes, being over the age of 65 (p <0.001), Karnofsky performance score (KPS) below 80 (p <0.001), diabetes (p = 0.017), having grad 4 pathology (p <0.001), performing subtotal excision / biopsy (p <0.001), hypofractioned / whole brain radiotherapy (p <0.001), and not receiving adjuvant chemotherapy (CT) (p <0.001) had a negative effect on overall survival (OS). In multivariate analyzes, being over 65 years old, having grad 4 pathology, performing subtotal excision / biopsy and not taking adjuvant CT were found to be effective on OS. Median overall survival in diabetics was 9.65 months and 17.74 months in non-diabetics (p = 0.017). No statistically significant relationship was found between BMI and OS. Conclusion: Pre-existing diabetes in malignant glioma patients is a risk factor for poor outcomes. It is important to control diabetes and related conditions.","PeriodicalId":444037,"journal":{"name":"Ortadoğu Tıp Dergisi","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115927280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thiol/disulfide homeostasis in patients with chronic hepatitis B 慢性乙型肝炎患者的硫/二硫体内平衡

Ortadoğu Tıp Dergisi Pub Date : 2020-06-01 DOI: 10.21601/ORTADOGUTIPDERGISI.752362

N. Çelik, C. Bicer, O. Çelik, A. Çarlıoğlu, M. Alışık

{"title":"Thiol/disulfide homeostasis in patients with chronic hepatitis B","authors":"N. Çelik, C. Bicer, O. Çelik, A. Çarlıoğlu, M. Alışık","doi":"10.21601/ORTADOGUTIPDERGISI.752362","DOIUrl":"https://doi.org/10.21601/ORTADOGUTIPDERGISI.752362","url":null,"abstract":"Amac: Bu calismanin amaci, oksidatif stres belirteci olarak kullanilan tiyol / disulfit dengesi ile kronik hepatit B (KHB) arasindaki iliskiyi degerlendirmektir. Gerec ve Yontem: Bu calisma Mayis 2016 - Temmuz 2016 tarihleri arasinda Erzurum Bolge Egitim ve Arastirma Hastanesi Enfeksiyon Hastaliklari Polikliniginde yapildi. Calismaya KHB’li 63 hasta ve bilinen herhangi bir hastaligi olmayan 60 saglikli gonullu dahil edildi. Dinamik tiyol /disulfit dengesini olcmek icin Erel ve Neselioglu tarafindan gelistirilen yeni otomatik analiz yontemini kullanildi. Dogal tiyolden (SH) sonra, toplam tiyol (toplam SH) ve disulfit (SS) seviyeleri belirlendi; SS/SH, SS/toplam SH ve SH/toplam SH gibi olculer hesaplandi. Bulgular: KHB grubunda, SH seviyelerinin (P=0,041), toplam SH seviyelerinin (P = 0,043) kontrol grubundan dusuk oldugunu tespit edildi. Anti-HBc toplam IgG ile toplam SH, SH, SH/toplam SH arasinda negatif korelasyon vardi, Anti-HBc toplam IgG ile SS/SH, SS/toplam SH orani arasinda pozitif korelasyon vardi. BMX indeksi ile toplam SH, SH, SH/toplam SH arasinda negatif, SS/total SH, SS/SH arasinda pozitif korelasyon vardi. Toplam protein, albumin ve toplam SH, SH arasinda pozitif korelasyon bulundu. Sonuc: Calismamizda KHB hastalarinda antioksidan olarak tiyol duzeyleri dusuk bulundu. Hepatit B’de tiyol duzeyinin yeni bir belirtec oldugu tekrar vurgulandi. Gelecekte yapilacak daha genis calismalarla KHB’de tiyol duzeyleri hem hastaligin seyrinin yavaslatilmasi hemde yeni tedavi gelistirme cabalarina isik tutacagi dusunulmektedir.","PeriodicalId":444037,"journal":{"name":"Ortadoğu Tıp Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131287024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Availability of Non-Ionizing Radiation Applications to Dispose Coronavirus from Foods and a Research on Creating Awareness in Protection from Coronavirus (COVID-19) 非电离辐射处理食品中冠状病毒的可行性及提高冠状病毒防护意识的研究

Ortadoğu Tıp Dergisi Pub Date : 2020-06-01 DOI: 10.21601/ORTADOGUTIPDERGISI.763775

Suleyman Gokmen, Ismail Ors

引用次数: 1

An unusual cause of acute abdomen in children: Mesenteric pseudocyst in the ileum 儿童急腹症的罕见病因:回肠肠系膜假性囊肿

Ortadoğu Tıp Dergisi Pub Date : 2020-06-01 DOI: 10.21601/ortadogutipdergisi.752193

M. Uysal

引用次数: 0

The severity of intrahepatic cholestasis of pregnancy can shorten the first stage of labor in multiparous women induced by prostaglandin E2 妊娠期肝内胆汁淤积的严重程度可缩短前列腺素E2诱导的多胎妇女第一产程

Ortadoğu Tıp Dergisi Pub Date : 2020-05-15 DOI: 10.21601/ORTADOGUTIPDERGISI.737898

Banuhan Şahin, S. Çelik, C. Soyer, Ş. Hatırnaz, H. Çelik

{"title":"The severity of intrahepatic cholestasis of pregnancy can shorten the first stage of labor in multiparous women induced by prostaglandin E2","authors":"Banuhan Şahin, S. Çelik, C. Soyer, Ş. Hatırnaz, H. Çelik","doi":"10.21601/ORTADOGUTIPDERGISI.737898","DOIUrl":"https://doi.org/10.21601/ORTADOGUTIPDERGISI.737898","url":null,"abstract":"Aim: To determine the relationship between increased serum bile acid concentrations and the first stage of labor in multiparous women induced by vaginal prostaglandin E2 (PGE2) with intrahepatic cholestasis of pregnancy (ICP). Material and Methods: In this retrospective case-control study 283 multiparous women with ICP and 283 healthy multiparous pregnant women were admitted for induction of delivery, were inserted PGE2 (10 mg dinoprostone) vaginally. The groups with mild, moderate and severe ICP were compared with control group in terms of the time from beginning of PGE2 vaginal insertion to active phase of labor, the time from beginning of PGE2 vaginal insertion to complete dilatation of cervix and fetal outcomes. Results: The time from beginning of PGE2 insertion to active phase in the mild, moderate and severe ICP groups were shorter than in the non-ICP group; 3.19±0.32, 7.26±0.34, 8.71±0.35 hours, respectively (p<0.01). The time from beginning of PGE2 insertion to complete dilatation of cervix in the groups with mild, moderate and severe ICP were shorter than in non-ICP group; 3.03 ± 0.45; 10.33 ± 0.62; 14.44 ± 0.53, respectively (p<0.01). There was no difference between the groups in terms of fetal outcomes except fetal weight and the presence of meconium (p<0.01). Conclusion: Increased bile acid concentrations in multiparous pregnant women induced by vaginal PGE2 with mild, moderate and severe ICP are associated with shorter duration of cervical ripening and labor induction time to delivery. The study concluded that multiparous women with ICP can deliver faster as the severity of cholestasis increases.","PeriodicalId":444037,"journal":{"name":"Ortadoğu Tıp Dergisi","volume":"4 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113965654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polymicrobial peritonitis case in a patient who underwent continuous ambulatory peritoneal dialysis result with exitus 多微生物性腹膜炎1例患者接受连续流动腹膜透析结果为exitus

Ortadoğu Tıp Dergisi Pub Date : 2020-05-15 DOI: 10.21601/ORTADOGUTIPDERGISI.612118

S. Cesur, Taliha Karakök, Ayşe Büyükdemirci, Salim Tece, S. Kınıklı, G. Gürsoy

引用次数: 0

The relationship between interleukin-6 and epileptic seizure 白细胞介素-6与癫痫发作的关系

Ortadoğu Tıp Dergisi Pub Date : 2020-04-19 DOI: 10.21601/ORTADOGUTIPDERGISI.651791

R. Ezer, Hülya Ertaşoğlu Toydemir, Fatma Münevver Gökyiğit

{"title":"The relationship between interleukin-6 and epileptic seizure","authors":"R. Ezer, Hülya Ertaşoğlu Toydemir, Fatma Münevver Gökyiğit","doi":"10.21601/ORTADOGUTIPDERGISI.651791","DOIUrl":"https://doi.org/10.21601/ORTADOGUTIPDERGISI.651791","url":null,"abstract":"Aim: The aim of this study was to evaluate the relationship between interleukin-6 (IL-6) levels and the type of the seizure, etiology of the seizure and the infection parameters which were fever, leukocyte count and c-reactive protein (CRP) in epileptic patients.\u0000Material and Methods: A total of 48 people were included in the study, containing a patient group of 24 and a control group of 24. IL-6, fever, leukocyte and CRP levels were measured and recorded. The patients were categorized according to the type and etiology of the seizures. The relationship between IL-6 levels and infection parameters, type and etiology of seizures were evaluated.\u0000Results: IL-6 levels were significantly higher in epileptic patients than that of the control group. There were no correlations between IL-6 levels and fever, leukocyte and CRP. The patients were evaluated according to the seizure type. There was no significant relationship between IL-6 levels of control group and IL-6 levels of patients with partial epileptic seizures (p=0.270). However, there was significant relationship between IL-6 levels of the control group and that of patients with primary generalized, secondary generalized seizures and generalized status epilepticus (p=0.012, p=0.011 and p=0.040, respectively). Epilepsy etiology was not associated with levels of IL-6.\u0000Conclusion: High levels of IL-6 after epileptic seizures might be detected independent from infection parameters and epilepsy etiology. IL-6 levels might be higher in patients with primary generalized, secondary generalized seizures and generalized status epilepticus than that of patients with partial seizures.","PeriodicalId":444037,"journal":{"name":"Ortadoğu Tıp Dergisi","volume":"435 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115935470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Non-alcoholic fatty liver disease in patients with familial hypercholesterolemia 家族性高胆固醇血症患者的非酒精性脂肪性肝病

Ortadoğu Tıp Dergisi Pub Date : 2020-04-18 DOI: 10.21601/ortadogutipdergisi.722778

A. Arslan, Özgür Şimşek, A. Turhan, A. Çarlıoğlu, Ş. Arıkan, M. Utlu, Emine Kartal Baykan

{"title":"Non-alcoholic fatty liver disease in patients with familial hypercholesterolemia","authors":"A. Arslan, Özgür Şimşek, A. Turhan, A. Çarlıoğlu, Ş. Arıkan, M. Utlu, Emine Kartal Baykan","doi":"10.21601/ortadogutipdergisi.722778","DOIUrl":"https://doi.org/10.21601/ortadogutipdergisi.722778","url":null,"abstract":"Amac: Karaciger, kolesterol sentezinde ve katabolizmasinda cok onemli rol oynar. Non-alkolik yagli karaciger hastaligi (NAYKH), gelismis ulkelerde kronik karaciger hastaliginin en sik sebebidir ve siklikla diabetes mellitus, hipertansiyon, dislipidemi ve obezite gibi metabolik hastaliklarla komorbidite gosterir. Bu calismanin amaci Ailevi Hiperkolesterolemide (AH) NAYKH gorulme sikligini arastirmaktir. Gerec ve Yontemler: 2017-2018 yillari arasinda Erzurum Bolge Egitim ve Arastirma Hastanesi Endokrinoloji Poliklinigine basvurmus olan AH’li kisiler tek merkezli bu vaka kontrol calismasina alindi. AH’li toplam 30 kisi (17 Kadin 13 erkek), 39 kisiden olusan (30 kadin, 9 erkek) kontrol grubu ile karsilastirildi. Iki grup sayi ve cinsiyet yonunden denkti. Aile oykusu kaydedildi. Tani kan tetkikleri ve karaciger ultrasonografisi ile kondu. Bulgular: Iki grup arasinda yas ve cinsiyet acisindan anlamli fark gorulmedi. NAYKH, kontrol grubundaki 39 kisiden 12’sinde saptanirken, AH grubunda 30 kisiden 16’sinda goruldu (p = 0,058). AH ve kontrol gruplarinin sirasiyla toplam kolesterol (333,27 ± 58,46) (219,23 ± 82,84) (mg / dl) (p = 0,000), LDL (249,93 ± 45,43) (127,11 ± 46,52) (mg / dl) (p = 0,000) ve CRP (3,37 ± 4,16) (1,43 ± 1,96) (mg / L) (p = 0,014) duzeyleri arasinda anlamli fark bulundu. Sonuclar: AH ve kontrol gruplari arasinda NAYKH acisindan anlamli bir fark yoktur. Ultrasonografide NAYKH saptanmamasi, AH’ye yaklasimdaki ciddiyeti azaltmamalidir.","PeriodicalId":444037,"journal":{"name":"Ortadoğu Tıp Dergisi","volume":"33 7-8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123341751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Frequency of personality types based on enneagram in a Turkish sample: A web-based cross-sectional study 土耳其样本中基于九型人格类型的频率:一项基于网络的横断面研究

Ortadoğu Tıp Dergisi Pub Date : 2020-04-18 DOI: 10.21601/ORTADOGUTIPDERGISI.722751

Zekeriya Aktürk, Kenan Tastan

{"title":"Frequency of personality types based on enneagram in a Turkish sample: A web-based cross-sectional study","authors":"Zekeriya Aktürk, Kenan Tastan","doi":"10.21601/ORTADOGUTIPDERGISI.722751","DOIUrl":"https://doi.org/10.21601/ORTADOGUTIPDERGISI.722751","url":null,"abstract":"Amac : Enneagram yuzlerce yildir bilinmesine ragmen, bu alandaki arastirmalar azdir. Bu calismanin amaci Turkce konusan bir orneklemin kisilik tiplerinin sikligini analiz etmek ve farkli kisiliklerin oranlarini demografik verilerle karsilastirmaktir. Yontem : Enneagram’a dayali bir arac olan Tastan Kisilik Tipleri Envanteri Google Formlar’da barindirildi ve universitenin akademik web sayfasi uzerinden kullanima sunuldu. Cevrimici yanitlar 08.04.2015 ve 22.8.2019 tarihleri arasinda toplanmistir. Calismanin katilimcilari Turkce konusan ergenler ve yetiskinlerdir. Bulgular : Bu arastirmada 1646 katilimcinin verileri analiz edildi. Ortalama (± SD) yas 29,48 ± 11,03 yil idi. En sik karsilasilan ana kisilik tipi 2 numarali “yardimci” (n = 335, %20,4), 8 numarali “meydan okuyucu” ise en sik karsilasilan kisilik kanadidir (284, %17,3). Tip 8 kisilik sikligi artan yasla birlikte azalirken, tip 3 kisilik icin tersi dogruydu (χ 2 = 130,623, p <0,001). Tip 1 kisilik erkeklerde daha yaygin iken (n = 51 (%9,5) ve n = 63 (%5,7)), tip 4 kadinlarda neredeyse iki kat fazlaydi (n = 48 (%8,9’a karsilik n = 183 (%16,5)) (χ 2 = 28,835, p <0,001) Ayrica, egitim duzeyi arttikca tip 1 kisilik olasiligi da artmaktadir (χ 2 = 67,316, p <0,001). Sonuc : Incelenen nufusun kisilik tiplerinde demografik degiskenler acisindan farkliliklar vardir. Bu bulgular kisilik tipinin besikten mezara kadar ayni olmadigini, egitim ve yasla degisebilecegini dusundurmektedir. Enneagram kisilik tiplerinin tanimlanmis populasyonlardaki belirli hastaliklarla iliskisi arastirmalidir.","PeriodicalId":444037,"journal":{"name":"Ortadoğu Tıp Dergisi","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123499341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4