Turkish Archives of Otorhinolaryngology最新文献

{"title":"Perineural Invasion of Superior and Inferior Laryngeal Nerves in Advanced Stage Squamous Cell Carcinoma of the Larynx: A Case Series and Review.","authors":"Avinash Shekhar Jaiswal,&nbsp;Sumanth Bollu,&nbsp;Shilpi Budhiraja,&nbsp;Seema Kaushal,&nbsp;Kapil Sikka,&nbsp;Alok Thakar,&nbsp;Hitesh Verma","doi":"10.4274/tao.2023.2023-2-12","DOIUrl":"https://doi.org/10.4274/tao.2023.2023-2-12","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate bilateral superior and recurrent laryngeal nerves for tumor spread in patients of advanced-stage laryngeal carcinoma undergoing surgical resection.</p><p><strong>Methods: </strong>A prospective study was conducted including biopsy-proven cases of laryngeal squamous cell carcinoma (SCC) that were planned for total laryngectomy. Patients with metachronous or synchronous SCC were excluded from the study. All patients underwent total laryngectomy, where both superior and recurrent laryngeal nerves were harvested along with the specimen, and the proximal ends of the nerves were marked for reference. Perineural invasion (PNI) was assessed in nerves within the tumor and in bilateral extra-laryngeal nerves.</p><p><strong>Results: </strong>The study included 22 patients with a mean age of 58 years. Intra-tumoral PNI was found in 7 of the 22 cases (32%). The free nerve margins of superior and recurrent laryngeal nerves, which were examined from proximal to distal orientation, showed no tumor infiltration in any of the cases.</p><p><strong>Conclusion: </strong>Perineural invasion of minor nerves constitutes a major pathway of spread. On the contrary, invasion of superior or recurrent laryngeal nerves does not constitute a route for tumor spread. Hence, there is no need to extend the surgical boundary for total laryngectomy to include these major nerves separately.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"20-24"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/99/tao-61-20.PMC10424581.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10366923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frontal Sinus Cholesteatoma Presenting with Intracranial and Orbital Complications: Diagnosis and Treatment.","authors":"Débora Cristina Gaspar Gonçalves,&nbsp;Tiago Soares Santos,&nbsp;Vera Claúdia Miranda Silva,&nbsp;Hugo Narcy Amaral Amorim Costa,&nbsp;Carlos Magalhães Ferreira Carvalho","doi":"10.4274/tao.2022.2022-7-7","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-7-7","url":null,"abstract":"<p><p>Frontal sinus keratoma or cholesteatoma is a rare disease of paranasal sinuses and presents as a slow-growing mass that becomes symptomatic as it grows to the surrounding structures. Intracranial complications are not a common presentation and are potentially life-threatening. Frequently the final diagnosis is only made intraoperatively because several other frontal sinus tumors behave likewise. Definitive treatment requires complete removal of the keratoma, and a combined endoscopic and external frontal sinus approach is a good treatment option. In this report, we presented a 68-year-old female with frontal sinus cholesteatoma with diagnostic and therapeutic features of this pathology with the review of the literature.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"234-237"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/9f/tao-60-234.PMC10339268.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10183555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Importance of Prostate-Specific Membrane Antigen Expression in Salivary Gland Tumors.","authors":"Mehmet Emre Sivrice,&nbsp;Hasan Yasan,&nbsp;Yusuf Çağdaş Kumbul,&nbsp;Onur Ertunç,&nbsp;Sarper Sayın","doi":"10.4274/tao.2022.2022-12-3","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-12-3","url":null,"abstract":"<p><strong>Objective: </strong>Prostate-specific membrane antigen (PSMA) is a cell membrane protein expressed by prostate tissues. It is not prostate specific and is also expressed by some non-prostatic solid neoplasms. Our study aimed to investigate the potential role of PSMA in salivary gland tumors.</p><p><strong>Methods: </strong>The present study was designed to retrospectively analyze our cases that presented with salivary gland tumors. The files of 105 patients were reviewed and their paraffin embedded blocks were retrieved from the pathology department. Immunohistochemical examination and staining were done using PSMA antibody. Tumor tissue PSMA immunohistochemical staining was scored semi-quantitatively with the modified quartile approach. Negative staining was scored 0, >0% and ≤25% tissue expression was considered weak (score 1), >25% and ≤50% tissue expression was considered mild (score 2), >50% and ≤75% tissue expression was considered moderate (score 3), and >75% tissue expression was considered strong (score 4).</p><p><strong>Results: </strong>Eighty-eight patients (55 males, 33 females) were included in the study. Forty-eight patients had pleomorphic adenoma (PA), 35 had Warthin's tumor (WT), two had mucoepidermoid carcinoma, two had adenoid cystic carcinoma, and one had squamous cell carcinoma. There was statistically significant difference in terms of PSMA expression between PA and WT (p=0.003). PSMA expression was high in PA and absent in WT.</p><p><strong>Conclusion: </strong>PSMA is a potential source of inspiration for future studies on the development of novel diagnostic and theranostic investigations of salivary gland tumors. Prospective studies targeting intratumoral PSMA in salivary gland tumors should be planned.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"206-211"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/aa/e2/tao-60-206.PMC10339265.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9825154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nasal Reactivity After Radiofrequency Ablation of Peripheral Branches of Posterior Nasal Nerve.","authors":"Samy Elwany,&nbsp;Ziad Mandour,&nbsp;Ahmed Aly Ibrahim,&nbsp;Remon Bazak","doi":"10.4274/tao.2022.2022-10-1","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-10-1","url":null,"abstract":"<p><strong>Objective: </strong>Transection or ablation of the posterior nasal nerve (TRPN) has been described as an adjunctive tool to reduce the symptoms of intractable allergic rhinitis (AR). The procedure, however, requires surgical skill and carries the risk of bleeding from the sphenopalatine artery. The aim of the present study is to describe radiofrequency ablation of the peripheral branches of the posterior nasal nerves within the inferior turbinates (RAPN) as an effective easier alternative to TRPN.</p><p><strong>Methods: </strong>The procedure was performed on 24 patients with intractable AR. Nasal reactivity was tested by cold dry air (CDA) provocation before and 12 months after the radiofrequency procedure. Visual analog scale and acoustic rhinometry were used to measure the changes in nasal reactivity subjectively and objectively.</p><p><strong>Results: </strong>Worsening of nasal symptoms following CDA provocation had significantly decreased after the RAPN procedure. Likewise, postoperative decrease in nasal volumes and minimal cross-sectional areas after CDA provocation were significantly less than the corresponding preoperative values.</p><p><strong>Conclusion: </strong>RAPN effectively reduces nasal reactivity in patients with AR. The procedure is simple, minimally invasive, and can be performed under local or general anesthesia.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"181-187"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f2/33/tao-60-181.PMC10339264.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10201668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam: Professor İ. Nazmi Hoşal","authors":"Umut Akyol","doi":"10.4274/tao.2023.2022-03","DOIUrl":"https://doi.org/10.4274/tao.2023.2022-03","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 1","pages":"177 - 180"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48401149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Relationship Between BPPV with Anxiety, Sleep Quality and Falls.","authors":"Deniz Uğur Cengiz,&nbsp;İsmail Demir,&nbsp;Sümeyye Demirel,&nbsp;Sanem Can Çolak,&nbsp;Tuğba Emekçi,&nbsp;Tuba Bayındır","doi":"10.4274/tao.2022.2022-8-6","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-8-6","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effects of dizziness on sleep quality and psychological status in patients with benign paroxysmal positional vertigo (BPPV) and to evaluate its relationship with falls.</p><p><strong>Methods: </strong>A Demographic Data Form, a Visual Vertigo Analog Scale, the Falls Efficacy Scale - International (FES-I), the Hospital Anxiety and Depression Scale (HADS), and the Pittsburgh Sleep Quality Index (PSQI) were administered in 102 individuals diagnosed with BPPV by videonystagmography test. The same scales were applied to 75 healthy volunteers as the control group, and the two groups were compared. The BPPV group was divided into two groups as posterior canal and lateral canal BPPV. These two groups were compared among themselves and with the control group.</p><p><strong>Results: </strong>A statistically significant difference was found between the BPPV and control groups, the lateral canal BPPV and posterior canal BPPV groups, the lateral canal BPPV and control groups, and the posterior canal BPPV and control groups in terms of total scores of the PSQI, the FES-I, and the HADS (p<0.001). In the regression model, the FES-I score was fully explained by the PSQI and HADS scores (p<0.001).</p><p><strong>Conclusion: </strong>BPPV significantly affects sleep quality, psychological state, and the risk of fall. The negative effects of BPPV restrict daily living activities, affect the prognosis of the disease, and increase the risk of falling. Considering that psychiatric issues and sleep problems increase the risk of falling in individuals with BPPV, counseling services on this issue would reduce the incidence of falls and related injuries.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"199-205"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/81/tao-60-199.PMC10339271.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9825152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Unique Cause of Upper Airway Obstruction in a Child: Laryngeal Lipoma.","authors":"Kerem Kökoğlu,&nbsp;İbrahim Ketenci","doi":"10.4274/tao.2022.2022-11-8","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-11-8","url":null,"abstract":"<p><p>There are lots of diseases causing pediatric upper airway obstruction and stridor. They can be both congenital or acquired. While congenital causes are laryngomalacia, vocal cord palsy, congenital subglottic stenosis, acquired ones range from infections to foreign bodies or neoplasms. Laryngeal neoplasms develop almost epithelial in origin. Non-epithelial tumors consist 1% of laryngeal neoplasms. Although lipoma is the most common soft tissue tumor, laryngeal involvement is very rare and seen in the ages between 40-60 years. A 13-month-old child who had laryngeal lipoma and upper airway obstruction was aimed to present in this paper.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"231-233"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/73/tao-60-231.PMC10339263.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10183551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Elderly Voice: Mechanisms, Disorders and Treatment Methods.","authors":"Süha Beton,&nbsp;Levent Yücel,&nbsp;Hazan Başak,&nbsp;Zahide Çiler Büyükatalay","doi":"10.4274/tao.2022.2022-8-1","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-8-1","url":null,"abstract":"<p><p>The elderly population is increasing globally. In Turkey, the population aged 65+ is predicted to grow to more than 15% of the whole population by 2050. Just like the rest of the body, the voice also changes with age. Voice changes throughout life have been reported in up to 52.4% of aged individuals and may have a negative impact on their quality of life. Voice is affected by various factors, including age, disease, hormones, medications, and physiological, psychological, and social conditions. A multidisciplinary approach is therefore needed to achieve the best voice outcomes. In this review, we summarize the mechanisms involved in voice changes in the elderly together with the applicable diagnostic and treatment methods.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"220-226"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/9f/tao-60-220.PMC10339270.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10201669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting Permanent Sensorineural Hearing Loss and Bone Conduction in Patients After Receiving Radiotherapy to the Head and Neck Region.","authors":"Birsen Yücel,&nbsp;Eda Erdiş,&nbsp;Seher Bahar,&nbsp;Ebru Akkaş Atasever,&nbsp;Mustafa Gürol Celasun,&nbsp;Emine Elif Altuntaş","doi":"10.4274/tao.2022.2022-6-2","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-6-2","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the factors affecting permanent sensorineural hearing loss (SNHL) and causing changes in bone conduction (BC) thresholds over time in patients after receiving radiotherapy (RT) or chemoradiotherapy (CRT) to the head and neck region.</p><p><strong>Methods: </strong>A total of 63 patients with irradiated HNC that were admitted to the Radiation Oncology Department between 2011 and 2018 were included in the study. All patients were assessed with pure tone audiometry at eight different time points (first before RT and last five years after completion of RT). A chi-square test was used to analyze the variables that affected permanent SNHL occurrence. Repeated measure analysis of variance was conducted to investigate the factors affecting change in the BC threshold at pure-tone average (0.5-2 kHz) and the air conduction (AC) threshold at 4 and 6 kHz frequencies over time.</p><p><strong>Results: </strong>Median follow-up was 52 months (range, 12-110 months). SNHL was found in 18 (14%) of the 126 ears. According to the receiver operating characteristic analysis, the cut-off values of cochlear D_mean and D_max radiation doses were 40 Gy [p=0.017, area under the curve (AUC): 0.676] and 45 Gy (p=0.008, AUC: 0.695). D_mean (≤40 Gy vs. >40 Gy) and D_max (≤45 Gy vs. >45 Gy) cochlear doses and age (≤40 vs. >40 years) were determined as factors affecting SNHL in the chi-square test. Repeated measures showed that BC thresholds between 0.5-2 kHz and AC thresholds at 4 and 6 kHz increased over time. Age (≤40 vs. >40 years), treatment of head and neck cancer (RT vs. CRT), cisplatin use, and D_mean (≤40 Gy vs. >40 Gy) and D_max cochlear dose (≤45 Gy vs. >45 Gy) were important factors affecting the course of BC threshold over time.</p><p><strong>Conclusion: </strong>D_mean and D_max cochlear doses and age were found to be associated with permanent SNHL. Conduction thresholds worsened over time at all frequencies, and this trend was affected by cochlear doses, age, CRT, and cisplatin use.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"212-219"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/34/a1/tao-60-212.PMC10339269.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10201666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effect of Musical Perception Activities on Speech Perception in Adult Cochlear Implant Users.","authors":"Başak Mutlu,&nbsp;Merve Torun Topçu,&nbsp;Mustafa Yüksel,&nbsp;Mahmut Tayyar Kalcıoğlu","doi":"10.4274/tao.2022.2022-8-3","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-8-3","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate clinical musical perception, analyze the relationship between speech recognition and music perception, and investigate the effects of a three-month musical perception activities on these parameters in adult cochlear implant (CI) users with post-lingual hearing loss.</p><p><strong>Methods: </strong>Free-field hearing and speech tests in a quiet environment, the Turkish matrix test, and the Turkish version of the clinical assessment of musical perception test were performed on 18 adult unilateral CI users before and after the three-month music training. Results were compared with those of 18 healthy controls.</p><p><strong>Results: </strong>Prior to the musical perception activities, word recognition scores, Turkish matrix test results, and 500, 1000, and 6000 Hz free-field hearing thresholds were significantly correlated with the clinical assessment of musical perception test scores in the CI group (p<0.047). Timbre recognition scores (p=0.019) had improved significantly in the CI group after the three-month musical perception activities. On the other hand, timbre recognition scores had significantly affected the Turkish matrix test results (R2adjusted=0.56).</p><p><strong>Conclusion: </strong>Our study showed that speech perception in noise and clinical musical perception measurements affected each other in CI users. The inclusion of musical perception activities to support an auditory rehabilitation program may contribute to increased speech recognition skills in noise.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"188-198"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/40/9c/tao-60-188.PMC10339267.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10201670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}