Journal of Critical Care Medicine最新文献_第10页

The Effect of the Antioxidant Drug “U-74389G” on Haemoglobin Levels Following a Hypoxemia/ Re-oxygenation Protocol in Rats 抗氧化药物“U-74389G”对大鼠低氧血症/再氧方案后血红蛋白水平的影响

IF 1.1

Journal of Critical Care Medicine Pub Date : 2015-05-01 DOI: 10.1515/jccm-2015-0017

C. Tsompos, C. Panoulis, K. Toutouzas, G. Zografos, A. Papalois

{"title":"The Effect of the Antioxidant Drug “U-74389G” on Haemoglobin Levels Following a Hypoxemia/ Re-oxygenation Protocol in Rats","authors":"C. Tsompos, C. Panoulis, K. Toutouzas, G. Zografos, A. Papalois","doi":"10.1515/jccm-2015-0017","DOIUrl":"https://doi.org/10.1515/jccm-2015-0017","url":null,"abstract":"Abstract Critically ill patients usually present with circulatory hypoxemia and this is associated with a poorer prognosis. The aim of this experimental study was to examine the effect of U-74389G with specific regard to a hypoxemia/re-oxygenation protocol, on mean blood haemoglobin (Hgb) levels in rats. Materials and methods: Forty rats (mean weight 231.9 g) were used in the study. Hgb levels were measured at sixty minutes (groups A and C) and at 120 minutes (groups B and D) of re-oxygenation. U-74389G was administered only in groups C and D. Results: U-74389G administration non-significantly increased the Hgb levels by 3.95+2.10% (p=0.0604). Re-oxygenation time non-significantly increased the Hgb levels by 3.39+2.12% (p=0.1285). U-74389G administration and reoxygenation time together, significantly increased the Hgb levels by 2.55%+1.25% (p=0.0423). Conclusions: Results of this study indicate that U-74389G administration, re-oxygenation time, but mainly their interaction significantly increase the Hgb levels within the studied time limits.","PeriodicalId":44227,"journal":{"name":"Journal of Critical Care Medicine","volume":"1 1","pages":"102 - 106"},"PeriodicalIF":1.1,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/jccm-2015-0017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66928839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The Reduction of Catheter-Related Blood Stream Infections through the Implementation of an Interdisciplinary Healthcare Team 通过跨学科医疗团队的实施减少导管相关血流感染

IF 1.1

Journal of Critical Care Medicine Pub Date : 2015-02-10 DOI: 10.1155/2015/635939

K. Scatliffe, A. Davis, Carla Wang-Kocik, Nelson Medina Villanueva, Maria Espiritu-Fuller, Renita Larang, Patricia Dimitriou, A. Doran, A. Repayo, Jeremias Murillo, C. Engell, Morris Cohen, J. Larosa

{"title":"The Reduction of Catheter-Related Blood Stream Infections through the Implementation of an Interdisciplinary Healthcare Team","authors":"K. Scatliffe, A. Davis, Carla Wang-Kocik, Nelson Medina Villanueva, Maria Espiritu-Fuller, Renita Larang, Patricia Dimitriou, A. Doran, A. Repayo, Jeremias Murillo, C. Engell, Morris Cohen, J. Larosa","doi":"10.1155/2015/635939","DOIUrl":"https://doi.org/10.1155/2015/635939","url":null,"abstract":"In December 2012, a multidisciplinary task force was implemented to address the elevated number of central line associated boodstream infections (CLABSIs) at Newark Beth Israel Medical Center from January 2012 to December 2012. Sixty-eight CLABSIs were documented within the adult inpatient population, resulting in a rate of 14.7 CLABSIs/1,000 central line days in the adult inpatient population. This was well above the national average of 1.87 infections per 1,000 central line days. Most of these infections were noted to be within the critical care units where the rate was at 2.86 CLABSIs/1,000 central line days. However, in 2013, the annual rate was decreased to 0.709 CLABSIs/1000 line days with similar trends observed across the critical care units. Analysis of CLASBI data indicates that the implementation of a multidisciplinary task force dedicated to appropriate central line insertion, maintenance, and the removal of unnecessary central venous catheters can have an impact on reducing rates of CLASBIs throughout the adult inpatient population, including those within critical care units.","PeriodicalId":44227,"journal":{"name":"Journal of Critical Care Medicine","volume":"2015 1","pages":"1-8"},"PeriodicalIF":1.1,"publicationDate":"2015-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/635939","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65073038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Prolonged Emergency Department Length of Stay as a Predictor of Adverse Outcomes in Patients with Intracranial Hemorrhage. 延长急诊科住院时间作为颅内出血患者不良结局的预测因子

IF 1.1

Journal of Critical Care Medicine Pub Date : 2015-01-01 DOI: 10.1155/2015/526319

Erica M Jones, Amelia K Boehme, Aimee Aysenne, Tiffany Chang, Karen C Albright, Christopher Burns, T Mark Beasley, Sheryl Martin-Schild

{"title":"Prolonged Emergency Department Length of Stay as a Predictor of Adverse Outcomes in Patients with Intracranial Hemorrhage.","authors":"Erica M Jones, Amelia K Boehme, Aimee Aysenne, Tiffany Chang, Karen C Albright, Christopher Burns, T Mark Beasley, Sheryl Martin-Schild","doi":"10.1155/2015/526319","DOIUrl":"https://doi.org/10.1155/2015/526319","url":null,"abstract":"Objectives: Extended time in the emergency department (ED) has been related to adverse outcomes among stroke patients. We examined the associations of ED nursing shift change (SC) and length of stay in the ED with outcomes in patients with intracerebral hemorrhage (ICH).Methods: Data were collected on all spontaneous ICH patients admitted to our stroke center from 7/1/08-6/30/12. Outcomes (frequency of pneumonia, modified Rankin Scale (mRS) score at discharge, NIHSS score at discharge, and mortality rate) were compared based on shift change experience and length of stay (LOS) dichotomized at 5 hours after arrival.Results: Of the 162 patients included, 60 (37.0%) were present in the ED during a SC. The frequency of pneumonia was similar in the two groups. Exposure to an ED SC was not a significant independent predictor of any outcome. LOS in the ED ≥5 hours was a significant independent predictor of discharge mRS 4-6 (OR 3.638, 95% CI 1.531-8.645, and P = 0.0034) and discharge NIHSS (OR 3.049, 95% CI 1.491-6.236, and P = 0.0023) but not death.Conclusions: Our study found no association between nursing SC and adverse outcome in patients with ICH but confirms the prior finding of worsened outcome after prolonged length of stay in the ED.","PeriodicalId":44227,"journal":{"name":"Journal of Critical Care Medicine","volume":"2015 2015","pages":""},"PeriodicalIF":1.1,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/526319","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34092988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Validation of Factors Affecting the Outcome of Cardiopulmonary Arrest in a Large, Urban, Academic Medical Center 大型城市学术医疗中心影响心肺骤停结果的因素验证

IF 1.1

Journal of Critical Care Medicine Pub Date : 2014-01-27 DOI: 10.1155/2014/168132

D. Koldobskiy, Soleyah Groves, S. Scharf, M. Cowan

{"title":"Validation of Factors Affecting the Outcome of Cardiopulmonary Arrest in a Large, Urban, Academic Medical Center","authors":"D. Koldobskiy, Soleyah Groves, S. Scharf, M. Cowan","doi":"10.1155/2014/168132","DOIUrl":"https://doi.org/10.1155/2014/168132","url":null,"abstract":"Background. Recent studies of risks in cardiopulmonary arrest (CPA) have been performed using large databases from a broad mix of hospital settings. However, these risks might be different in a large, urban, academic medical center. We attempted to validate factors influencing outcomes from CPA at the University of Maryland Medical Center (UMMC). Methods. Retrospective chart review of all adult patients who underwent CPA between 2000 and 2005 at UMMC. Risk factors and outcomes were analyzed with appropriate statistical analysis and compared with published results. Results. 729 episodes of CPA were examined during the study period. Surgical patients had better survival than medical or cardiac patients. Intensive care unit' (ICU) patients had poor survival, but there was no difference on monitored or unmonitored floors. Respiratory etiologies survived better than cardiac etiologies. CPR duration and obesity were negatively correlated with outcome, while neurologic disease, trauma, and electrolyte imbalances improved survival. Age, gender, race, presence of a witness, presence of a monitor, comorbidities, or time of day of CPA did not influence survival, although age was associated with differences in comorbidities. Conclusions. UMMC risk factors for CPA survival differed from those in more broad-based studies. Care should be used when applying the results of database studies to specific medical institutions.","PeriodicalId":44227,"journal":{"name":"Journal of Critical Care Medicine","volume":"2014 1","pages":"1-7"},"PeriodicalIF":1.1,"publicationDate":"2014-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/168132","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64374779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

A National Survey of Pediatric Intensive Care Units in Pakistan 巴基斯坦儿科重症监护病房全国调查

IF 1.1

Journal of Critical Care Medicine Pub Date : 2014-01-05 DOI: 10.1155/2014/842050

A. Haque, L. Ladak, M. Hamid, S. Mirza, N. Siddiqui, Z. Bhutta

{"title":"A National Survey of Pediatric Intensive Care Units in Pakistan","authors":"A. Haque, L. Ladak, M. Hamid, S. Mirza, N. Siddiqui, Z. Bhutta","doi":"10.1155/2014/842050","DOIUrl":"https://doi.org/10.1155/2014/842050","url":null,"abstract":"Purpose. To describe the structure, staffing resources, equipment, academic activities, and characteristics of pediatric population of pediatric intensive care units across the country. Material & Method. This was a prospective, descriptive, and observational survey of pediatric intensive care units from January to December 2009 across Pakistan. A questionnaire survey was emailed to director of each unit. Results. 16 PICUs were participated in this survey (100% response rate). A total of units with 155 beds were identified (1.1 bed /500,000 children). Regarding the categories, 12 (75%) were medical, 3 (19%) were pure cardiac intensive care units, and one unit (6%) was combined multidisciplinary cardiothoracic unit. 13 (81%) units were in public sector as compared to 3 (19%) were in private sector. The mean unit size was 9.7 (range 4–28) beds. Twelve (75%) units were located in three large cities. Only 3 (19%) units have trained intensivist. 37% (6/16) had nurse to patient ratio of 1 : 1-1 : 2 while others had ratios of 1 : 3–1 : 5 with all nurses specialized trained for pediatric intensive care units with bachelor degree or diploma in nursing. Only 50% had capacity for invasive monitoring. Conclusion. We found inadequacies in several aspects of PICUs in Pakistan including fewer PICUs, inadequate PICU beds, and lack of trained personal to look after critically ill pediatric population.","PeriodicalId":44227,"journal":{"name":"Journal of Critical Care Medicine","volume":"2014 1","pages":"1-4"},"PeriodicalIF":1.1,"publicationDate":"2014-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/842050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64705027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Refractory Status Epilepticus: Experience in a Neurological Intensive Care Unit 顽固性癫痫持续状态:在神经重症监护室的经验

IF 1.1

Journal of Critical Care Medicine Pub Date : 2014-01-02 DOI: 10.1155/2014/821462

O. Hernández, J. Zapata, M. Jiménez, M. Massaro, A. Guerra, J. Arango, J. Ciro, H. Delgado, J. Suarez

{"title":"Refractory Status Epilepticus: Experience in a Neurological Intensive Care Unit","authors":"O. Hernández, J. Zapata, M. Jiménez, M. Massaro, A. Guerra, J. Arango, J. Ciro, H. Delgado, J. Suarez","doi":"10.1155/2014/821462","DOIUrl":"https://doi.org/10.1155/2014/821462","url":null,"abstract":"Introduction. Refractory status epilepticus (RSE) has significant morbidity and mortality, and its management requires an accurate diagnosis and aggressive treatment. Objectives. To describe the experience of management of RSE in a neurological intensive care unit (NeuroICU) and determine predictors of short-term clinical outcome. Methods. We reviewed cases of RSE from September 2007 to December 2008. Management was titrated to findings on continuous video EEG (cVEEG). We collected patients’ demographics, RSE etiology, characteristics of seizures, cVEEG findings, treatments, and short-term outcome. Control of RSE was to achieve burst suppression pattern or electrographic cessation of ictal activity. Results. We included 80 patients; 63.8% were in coma, 25% had subclinical seizures, and 11.3% had focal activity. 51.3% were male and mean age was 45 years. Etiology was neurological lesion in 75.1%, uncontrolled epilepsy in 20%, and systemic derangements in 4.9%. 78.8% were treated with general anesthesia and concomitant anticonvulsant drugs. The control of RSE was 87.5% of patients. In-hospital mortality was 22.5%. The factors associated with unfavorable short-term outcome were coma and age over 60 years. Conclusions. RSE management guided by cVEEG is associated with a good seizure control. A multidisciplinary approach can help achieve a better short-term functional outcome in noncomatose patients.","PeriodicalId":44227,"journal":{"name":"Journal of Critical Care Medicine","volume":"2014 1","pages":"1-9"},"PeriodicalIF":1.1,"publicationDate":"2014-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/821462","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64691654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3