The Use of Hydroxyurea in the Treatment of COVID-19.

IF 0.9 Q4 CRITICAL CARE MEDICINE
Journal of Critical Care Medicine Pub Date : 2021-11-06 eCollection Date: 2021-10-01 DOI:10.2478/jccm-2021-0019
Melissa Robin Bowman Foster, Ali Atef Hijazi, Rebecca Opoku, Priya Varghese, Chun Li
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引用次数: 3

Abstract

Introduction: The rapid worldwide spread of COVID-19 motivated medical professionals to pursue and authenticate appropriate remedies and treatment protocols. This article aims to analyze the potential benefits of one treatment protocol developed by a group of care providers caring for severe COVID-19 patients.

Methods: The clinical findings of COVID-19 patients who were transferred to a specialized care hospital after unsuccessful treatment in previous institutions, were analyzed. The specialized care hospital used a treatment protocol including hydroxyurea, a medication commonly used for sickle cell treatment, to improve respiratory distress in the COVID-19 patients. None of the COVID-19 patients included in the analyzed data were diagnosed with sickle cell, and none had previously taken hydroxyurea for any other conditions.

Results: In all presented cases, patients reverted to their baseline respiratory health after treatment with the hydroxyurea protocol. There was no significant difference in the correlation between COVID-19 and hydroxyurea. However, deaths were extremely low for those taking hydroxyurea.

Conclusions: Fatality numbers were extremely low for those taking hydroxyurea; death could be attributed to other underlying issues.

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羟基脲在COVID-19治疗中的应用。
导论:COVID-19在全球的迅速传播促使医疗专业人员寻求并验证适当的补救措施和治疗方案。本文旨在分析一组护理人员为重症COVID-19患者制定的一种治疗方案的潜在益处。方法:分析在原机构治疗失败转专科医院的新冠肺炎患者的临床表现。专门护理医院使用了包括羟基脲在内的治疗方案,羟基脲是一种常用于镰状细胞治疗的药物,以改善COVID-19患者的呼吸窘迫。分析数据中纳入的COVID-19患者均未被诊断为镰状细胞,此前也没有人因任何其他疾病服用过羟基脲。结果:在所有病例中,患者在羟基脲方案治疗后恢复到基线呼吸健康。COVID-19与羟基脲的相关性无显著差异。然而,服用羟基脲的人死亡率极低。结论:羟基脲致死率极低;死亡可归因于其他潜在问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Critical Care Medicine
Journal of Critical Care Medicine CRITICAL CARE MEDICINE-
CiteScore
2.00
自引率
9.10%
发文量
21
审稿时长
11 weeks
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