Acta Oncologica Turcica最新文献_第4页

Evaluation of efficacy and toxicity of anthracycline plus cyclophosphamide every three weeks followed by weekly paclitaxel: The Izmır Oncology Group (IZOG) Study 每三周评估一次蒽环类药物加环磷酰胺，随后是每周紫杉醇的疗效和毒性:Izmır肿瘤组(IZOG)研究

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2019.05668

H. Taskaynatan, Y. Cankurtaran, Y. Kucukzeybek, A. Alacacıoğlu, Y. Yildiz, T. Salman, U. Oflazoğlu, U. Varol, Seray Sever, M. Tarhan

引用次数: 0

Clinicopathological Features of Young Gastric Cancer and New Inflammatory Prognostic Markers 青年胃癌的临床病理特征及新的炎症预后指标

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2023.74317

A. Gülmez, M. Dikilitas

{"title":"Clinicopathological Features of Young Gastric Cancer and New Inflammatory Prognostic Markers","authors":"A. Gülmez, M. Dikilitas","doi":"10.5505/aot.2023.74317","DOIUrl":"https://doi.org/10.5505/aot.2023.74317","url":null,"abstract":"Introduction: This study aimed to evaluate the clinicopathologic features of young gastric cancer (GC) patients and to investigate the factors affecting survival (OS). Materials and methods: In this study, the data of 55 patients diagnosed under the age of 40 were obtained by retrospective evaluation of hospital records. Clinicopathological features and some laboratory parameters of this patient group and new inflammatory prognostic markers (IPM) obtained from these parameters were evaluated. Results: The mean age of the patients in this study was 33 years. The majority of the patients were male. Patients were evaluated according to human C-erbB2 positivity too. The identified patients as positive were only 7% of all patients. Also, the patients were evaluated for platinum sensitivity too. It was found that 30% of the patients were sensitive to platinum treatments. Also, survival times of the patients were evaluated with IPM. Neutrophil-lymphocyte ratio (NLR), mean platelet volume/platelet count, C-reactive protein/albumin ratios were calculated separately. Survival results were analyzed based on the mean values of all 3 prognostic markers. Even though there was a significant numerical difference, no statistical significance was found. Discussion: This study was conducted to examine the clinicopathological features and survival time of young GC patients. Low C-erbB2 positivity and high platinum resistance were found among this patient population. In addition, inflammatory prognostic markers, which were found to be associated with survival in most cancers, were found to cause significant numerical differences in terms of survival in our study.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121096513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Effects of Ibandronic Acid and Zoledronic Acid on Progression-free Survival in Patients with Bone Metastatic Breast Cancer 评价依邦膦酸和唑来膦酸对骨转移性乳腺癌患者无进展生存期的影响

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2023.82346

E. Karaman, S. Kisioglu

引用次数: 0

Frequency of ASFA 3 Category Therapeutic Plasmapheresis in Reanimation Intensive Care Units 康复重症监护病房ASFA 3类治疗性血浆置换的发生频率

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2019.54771

A. Yikilmaz, F. Bozkurt, S. Akıncı, I. Dilek

引用次数: 0

Evaluation of Effect and Side Effects of Pemetrexed in Patients with Advanced-Stage Lung Adenocarcinoma 培美曲塞治疗晚期肺腺癌的疗效及副作用评价

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2022.23500

Serkan Gökçay, E. Atağ

引用次数: 1

Neurofibromatosis Type 1 and Type2 (NF1 and NF2): Molecular Genetic Profiles of the Patients 1型和2型神经纤维瘤病(NF1和NF2):患者的分子遗传谱

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2023.10692

A. Bakır, V. Topçu, B. Cavdarli

引用次数: 0

BRCA and non-BRCA Variants Detected by Next Generation Sequencing in Patients with Hereditary Breast and/or Ovarian Cancer Syndrome 下一代测序检测遗传性乳腺癌和/或卵巢癌综合征患者的BRCA和非BRCA变异

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2022.82246

Hamide Betül Gerik-Çelebi, H. Bolat

引用次数: 0

Palbociclib Associated Deep Vein Thrombosis: A Case Report 帕博西尼相关深静脉血栓1例报告

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2022.59751

E. Şenocak Taşçı, Özlem Sönmez

引用次数: 0

Which is the Best Strategy in Local Advanced Larynx Cancer? Total Laryngectomy Plus Radiotherapy or Larynx Preservation with Chemoradiotherapy: Single Center Experience 局部晚期喉癌的最佳治疗策略是什么?全喉切除术加放疗或喉保留加放化疗:单中心经验

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2022.05658

Mete Gündoğ, Hatice Basaran, Alperen Vural, Esin Kiraz, C. Eroglu, İ. Yüce, S. Çağlı

{"title":"Which is the Best Strategy in Local Advanced Larynx Cancer? Total Laryngectomy Plus Radiotherapy or Larynx Preservation with Chemoradiotherapy: Single Center Experience","authors":"Mete Gündoğ, Hatice Basaran, Alperen Vural, Esin Kiraz, C. Eroglu, İ. Yüce, S. Çağlı","doi":"10.5505/aot.2022.05658","DOIUrl":"https://doi.org/10.5505/aot.2022.05658","url":null,"abstract":"Objectives: The treatment of locally advanced laryngeal cancer (LALC) is very challenging. In the last few decades there has been a shift from total laryngectomy towards organ-sparing approaches. The aim of the current study is to compare oncological outcomes between surgery (total laryngectomy) followed by radiotherapy and larynx preservation with chemoradiotherapy (CRT). Materials and Methods: 114 patients with stage III-IV laryngeal cancer were included in the study, between 2009 and 2018. Thirty-six patients (31.6%) were performed total laryngectomy followed by radiotherapy and 78 (68.4%) underwent the larynx preservation approach. Survival differences between the groups were examined with the Kaplan-Meier test and cox-regression tests for factors affecting survival. Results: 5-year overall survival (OS) was found 66.3 months and 74.1 months, in the larynx preservation and the surgical groups, respectively (p=0.29). There was no statistically difference between groups for OS in the patients with T3/N0-N1 (p=0.76), but surgical groups had longer OS in the patients with T3/N2-N3 (p=0.04). There was no statistically difference between groups for OS in the patients with T4/N0-N1 (p=0.47), however CRT groups had longer OS in the patients with T4/N2-N3 (p=0.02). The N2-N3 was the factor associated with poor progression-free survival and distant metastasis free survival in multivariate analysis (p<0.01). Age (≥65) was associated with a 2.1-fold increased risk of death (p=0.01). The trans-glottis tumors were associated with a 3.6-fold increased risk of tracheostomy (p<0.01). Conclusion: The N0-N1 and N2-N3 should also be considered as well as advanced T-category for the treatment of LALC.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"227 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134582084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gynecologic Clinicopathological Evaluation of Women with Breast Cancer Using Tamoxifen 使用他莫昔芬治疗女性乳腺癌的妇科临床病理评价

Acta Oncologica Turcica Pub Date : 1900-01-01 DOI: 10.5505/aot.2022.24540

Anil Turhan cakir, Rıfat Şener, Muhammet Atay Özten, G. Sel, M. Harma, M. Harma

引用次数: 0