{"title":"Clinical outcomes and associated risk factors of cataract surgeries in patients with diabetic macular edema: A real-world study","authors":"S. Bassi, Shebin Salim, E. Rishi","doi":"10.4103/njvd.njvd_2_23","DOIUrl":"https://doi.org/10.4103/njvd.njvd_2_23","url":null,"abstract":"Purpose: To evaluate the clinical outcome of phacoemulsification with intravitreal bevacizumab (IVB) injection in patients with cataract and diabetic macular edema (DME) and to evaluate the risk factors for poor visual outcome. Methods: Retrospective study of 63 eyes of 60 patients with cataract and DME who underwent phacoemulsification with IVB injection. Best corrected visual acuity (BCVA) and central macular thickness (CMT) over 3 months were studied. Univariate binary logistic regression was done to assess the risk factors for poor visual outcome (BCVA <6/60) at the 3 months. Results: The mean baseline BCVA in log Mar scale ± SD was 0.94 ± 0.58. The mean BCVA at 3 weeks after the surgery was 0.52 ±0.47, and at 3 months was 0.49±0.37. At 3 weeks, the mean CMT (N = 47) was 437.27±217.48 compared with the mean preoperative CMT of 380.87±176.38 in the same set (P = 0.01). The mean CMT at 3 months was 457.97 ± 206.94 (N=40) compared to preoperative mean CMT 435.45 ± 146.13 in the same set (p value 0.52). Fifteen eyes (23.8%) were given a second IVB at the 3-week follow-up. In these eyes, the mean preoperative and 3-month mean CMT were 413.73 and 377, respectively. The risk factors for poor visual outcome were, male gender [odds ratio (OR) 3.333], poor preoperative visual acuity (OR 8.42) and posterior capsular dehiscence (OR 5.1). Conclusions: Phacoemulsification with IVB injection improved the visual acuity at 3 weeks and 3 months but the mean CMT increased at 3 weeks and a decreased at 3 months only after the second IVB injection. Poor presenting visual acuity was an independent risk factor for poor visual outcome.","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131405391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitreoretinal Society of Nigeria participation in the Preferences and Trends Survey of the American Society of Retina Specialists","authors":"O. Okonkwo, O. Adenuga, Shuaib Abdulsalam","doi":"10.4103/njvd.njvd_4_23","DOIUrl":"https://doi.org/10.4103/njvd.njvd_4_23","url":null,"abstract":"","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134442498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical coherence tomography and optical coherence tomography angiography biomarkers for age-related macular degeneration and retinovascular diseases","authors":"M. Udoh, A. Okudo, O. Okonkwo","doi":"10.4103/njvd.njvd_3_23","DOIUrl":"https://doi.org/10.4103/njvd.njvd_3_23","url":null,"abstract":"Optical coherence tomography (OCT) and OCT angiography (OCTA) play a vital role in diagnosing and posttreatment evaluation of several retina diseases, including age-related macular degeneration, diabetic retinopathy, and retinal vein occlusion, which are leading causes of retinal blindness. OCT provides a fast, noninvasive, and reproducible option for assessing retinal structure and gives high-resolution images that enable the identification of several biomarkers of retinal disease. Retinal biomarkers have been investigated extensively because of their usefulness in predicting the outcome and progression of disease. Recently, several biomarkers have been analyzed using artificial intelligence, which provides invaluable information on the natural history, prognosis, and risk of disease progression. Combining OCT/OCTA and artificial intelligence-based analytics will open doors to more personalized treatment and improved decision-making and, therefore, better outcomes for patients who suffer from retinal diseases. This review provides essential information on known retina biomarkers in leading retinal diseases.","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116276537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pigmented paravenous chorioretinal atrophy: A fortuitous finding in a patient with fronto-ethmoidal mucocoele","authors":"Y. Babalola, A. Ibiyemi","doi":"10.4103/njvd.njvd_1_23","DOIUrl":"https://doi.org/10.4103/njvd.njvd_1_23","url":null,"abstract":"A 56-year-old Nigerian male patient presented to the eye clinic with a six-month history of progressive deterioration of vision in the right eye which was preceded by a one-month history of swelling above the right eye. He had no visual complaints in the left eye and no concurrent systemic illnesses. The best corrected visual acuity was hand movement with accurate light projection in the right eye and 6/6 in the left eye. On ocular examination, a right proptosis with inferotemporal displacement was present. A right relative afferent pupillary defect was noted while the left anterior segment examination was normal. Binocular indirect ophthalmoscopy of the right eye revealed a cup-to-disc ratio of 0.6, temporal disc pallor, peripapillary atrophy, and clumps of pigmentation along the venous arcades with generalized chorioretinal atrophy involving the area of the fovea. The cup-to-disc ratio was 0.4 with mild temporal disc pallor and iridescent spots at the macula with similar features of bony spicule-like clumps in the right eye present along the superotemporal arcade in the left eye. Optical coherence tomography (OCT) scan revealed disorganization of the inner retinal layers with intraretinal reflective foci with back-shadowing and both retinal pigment epithelium and choroidal atrophy. The OCT of the left eye showed a few intraretinal reflective foci and retinal pigment epithelium and choroidal atrophy. From the clinical and OCT findings, a diagnosis of pigmented paravenous chorioretinal atrophy and right fronto-ethmoidal mucocele is made.","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133886918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vascular endothelial growth factor inhibitors (anti-VEGF) use in Nigeria: The way forward","authors":"S. Nwosu","doi":"10.4103/njvd.njvd_10_22","DOIUrl":"https://doi.org/10.4103/njvd.njvd_10_22","url":null,"abstract":"Intraocular neovascularization is a serious, blinding complication of diverse ischemic retinal vascular disorders. The treatment includes the use of vascular endothelial growth factors inhibitors (anti-VEGF), which are administered via intraocular injections. The commonly used anti-VEGF include bevacizumab, ranibizumab, and aflibercept. Although ranibizumab and aflibercept are approved for intraocular application, bevacizumab is used “off-label.” This article reviews the advantages and drawbacks of the anti-VEGF use and the implications for Nigeria where eye diseases requiring anti-VEGF treatment are also prevalent.","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"61 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114121931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leber’s miliary aneurysm in an Asian woman: A case report","authors":"Osayem Otabor-Olubor, LO Ekechukwu","doi":"10.4103/njvd.njvd_12_22","DOIUrl":"https://doi.org/10.4103/njvd.njvd_12_22","url":null,"abstract":"Leber miliary aneurysm is a part of the primary retinal telangiectasia spectrum. It usually presents in middle-aged males with retinal hard exudates and aneurysmal changes of the retinal vessels. It is often unilateral, and typically affects the temporal aspect of the retina. Treatment is with light laser photocoagulation and cryotherapy. We present a case of a 33-year-old Bangladeshi female who presented with gradual blurring of vision, with hard exudates and retinal vessel aneurysm and dilatation seen on her temporal retina. The temporal aspect of the macula was also involved.","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130519540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Mahendradas, S. Sanjay, Aditya Dilipkumar Patil, P. Srinivasan
{"title":"Unilateral foveolitis, hyperhomocysteinemia, and dengue fever","authors":"P. Mahendradas, S. Sanjay, Aditya Dilipkumar Patil, P. Srinivasan","doi":"10.4103/njvd.njvd_9_22","DOIUrl":"https://doi.org/10.4103/njvd.njvd_9_22","url":null,"abstract":"We describe a unique case of post-dengue fever (DF) central retinal vein occlusion (CRVO) with foveolitis and concomitant hyperhomocystinemia. A 21-year-old Asian Indian woman presented with a sudden decrease in vision in left eye (OS) 3 days after fever. Clinically she had impending CRVO with foveolitis in OS. Serology for dengue immunoglobulin G was positive (65.74) and serum homocysteine level was elevated (>50). Spectral-domain optical coherence tomography revealed posterior vitreous cells, altered foveal contour, a well-defined area of hyperreflectivity in the subfoveal region with disruption of outer nuclear layer, and external limiting membrane with subretinal fluid with intact retinal pigment epithelium suggestive of the foveolitis, most commonly described in DF. She was treated with systemic steroids and folic acid, with complete resolution of her clinical signs after 6 weeks. In addition to the hematological workup, history of fever DF should be considered as a possible etiology in a case of vein occlusion","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134255261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurat Adeleye, Chidinma Ohuabunwa, A. Okudo, Aisha Abubakar
{"title":"Central serous chorioretinopathy following ingestion of sympathomimetics: A case report from Abuja, Nigeria","authors":"Nurat Adeleye, Chidinma Ohuabunwa, A. Okudo, Aisha Abubakar","doi":"10.4103/njvd.njvd_14_22","DOIUrl":"https://doi.org/10.4103/njvd.njvd_14_22","url":null,"abstract":"Central serous chorioretinopathy (CSCR) manifests mainly with the buildup of fluids beneath the retina often leading to distorted vision. This case report describes a patient with CSCR. A 34-year-old man presented to the eye clinic in October 2019 with complaints of blurry vision and metamorphopsia, which got worsened after 5 months of no treatment. The patient had a history of intake of a mixture containing phenylephrine, pseudoephedrine, and ephedrine over a period of 3 years for recurrent cold. Upon examination, his visual acuity was RE 6/9 LE 6/7.5 and his left macula was seen having a round serous detachment with creamy-white subretinal deposits. Optical coherence tomography revealed a retinal thickness of 360.5 ± 94.7 µm and macular edema. He was treated with intravitreal ranibizumab and cessation of sympathomimetic drugs with a modest visual improvement achieved within a month. There has been no reoccurrence over the 2-year period he was followed up. There could be an association between chronic ingestion of sympathomimetics and the risk of developing CSCR.","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128570031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Valsalva retinopathy in Nigerians: A case series","authors":"T. Akanbi, O. Oderinlo","doi":"10.4103/njvd.njvd_15_22","DOIUrl":"https://doi.org/10.4103/njvd.njvd_15_22","url":null,"abstract":"Valsalva retinopathy is considered rare. Patients present with sudden visual loss due to premacular hemorrhage. Treatment depends on the presentation. Three patients presented to us between 2013 and 2022 with sudden visual loss caused by Valsalva retinopathy. Case 1 was a 26-year-old female primigravida with right premacular hemorrhage after severe vomiting which was treated with pneumatic displacement with air. Case 2 was a 23-year-old male with left premacular hemorrhage. He had no memory of a Valsalva maneuver. He had vitrectomy for premacular dehemoglobinized non-resolving hemorrhage. Case 3 was a 27-year-old pregnant female with left premacular hemorrhage after vomiting. She was managed conservatively. Large, dense, or non-resolving hemorrhages require treatment while small hemorrhages may spontaneously resolve. The patients had different treatment strategies with good outcomes","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132048102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Idris Saka, M. Balogun, B. Adekoya, B. Balogun, C. Ekumankama, Ro Ngwu, M. Fashola, Ufoma Olumodeji
{"title":"Outcome of retropupillary Iris claw lens implantation at Lagos State University Teaching Hospital","authors":"Idris Saka, M. Balogun, B. Adekoya, B. Balogun, C. Ekumankama, Ro Ngwu, M. Fashola, Ufoma Olumodeji","doi":"10.4103/njvd.njvd_13_22","DOIUrl":"https://doi.org/10.4103/njvd.njvd_13_22","url":null,"abstract":"Introduction: Cataract surgery with intraocular lens (IOL) implantation is one of the most common intraocular surgeries performed in the Department of Ophthalmology of the Lagos State University Teaching Hospital (LASUTH). Failure to implant an IOL in the posterior chamber can result in a compromised posterior capsule because of rupture or weak zonular support. Iris claw lens (ICL) implantation posterior to the iris (retropupillary) allows for posterior chamber implantation in the absence of adequate capsular support. Objectives: To assess the immediate and short-term outcomes of retropulillary ICL implantation as well as the immediate and short-term complications in patients at the LASUTH. Materials and Methods: A retrospective analysis of all patient case notes seen from January 2022 to November 2022 at the Ophthalmology department of LASUTH who met the inclusion criteria and had ICL implantation were collected and assessed. Patient’s demographic data, indication for ICL implantation, visual status preoperatively, postoperatively, and complications were analyzed. Results: A total of 20 eyes of 20 patients had the procedure in the study period. The age range was 12–70 and the longest follow-up period was 7 months with the shortest being 3 weeks. The mean preoperative visual acuity was 3/60, and the mean postoperative best-corrected distant visual acuity was 6/12. Immediate postoperative complications were uveitis (23%), raised IOP (5%), hypotony (10%), vitreous inflammation (13%), and cornea edema (13%). Conclusion: Retropupillary ICL implantation carries a good postoperative visual outcome; it is encouraged that this procedure is considered as an alternative to both anterior chamber IOL and scleral fixated IOL.","PeriodicalId":433701,"journal":{"name":"Nigerian Journal of Vitreoretinal Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125793883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}