Marmara Medical Journal最新文献

{"title":"The relationship between renal functions and multi-drug resistant organisms in patients with ventilator-associated pneumonia","authors":"Omur Ilban, Aysegul Ilban","doi":"10.5472/marumj.1244732","DOIUrl":"https://doi.org/10.5472/marumj.1244732","url":null,"abstract":"Objective: Despite the increase in the frequency of multi-drug resistant organism (MDRO) colonisation and infection in dialysis \u0000patients, it is not well known whether the risk of multi-drug resistant (MDR) pneumonia increases in mild-to-severe chronic kidney \u0000disease patients not undergoing dialysis. Therefore, we aimed to evaluate the relationship between renal functions and the risk of MDR \u0000ventilator-associated pneumonia (VAP) and the specific microbial pattern. \u0000Patients and Methods: A total of 133 patients who developed VAP were divided according to their renal function into two groups, an \u0000estimated glomerular filtration rate of (eGFR) ≥ 60 mL/ min/1.73 m2 (high eGFR, n=65) and eGFR < 60 mL/min/1.73 m2 (low eGFR, \u0000n=68). \u0000Results: The low eGFR group presented a significantly high MDRO ratio (p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44511664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of autonomic nervous system functions by using tilt table test and heart rate variability in epileptic children","authors":"Azad Redjepov, Sinem Altunyuva Usta, Y. Yildirim, F. Akalın","doi":"10.5472/marumj.1244552","DOIUrl":"https://doi.org/10.5472/marumj.1244552","url":null,"abstract":"Objective: The value of head-up tilt test (HUTT) for differential diagnosis of epilepsy and the autonomic nervous system functions in \u0000epileptic children using heart rate variability (HRV) are studied. \u0000Patients and Methods: The study group consisted of 16 children with idiopatic/criptogenic epilepsy and 12 controls. Heart rate, PR \u0000interval, corrected QT (QTc) interval, QT and QTc dispersion were calculated using 12-lead electrocardiogram (ECG), HRV analysis \u0000was performed using the Holter recordings obtained both during HUTT and throughout the day. Time domain parameters, standard \u0000deviation of all RR intervals (SDNN), the standard deviation of mean NN intervals in five-minutes recording (SDANN), mean standard \u0000deviation of NN intervals in five-minutes recordings (SDNNi), root mean square of successive differences (RMSSD), count divided \u0000by the total number of all NN intervals (pNN50) and frequency domain parameters low frequency (LF), high frequency (HF), lowfrequency/ \u0000high-frequency ratio (LF/HF) were calculated in both and compared between the two groups. \u0000Results: Head-up tilt test was positive in 4 epileptic children (25%), none of controls were positive. The heart rate of the patients were \u0000higher than the controls (p=0.015). LF/HF ratio in 24-hour Holter recordings, were significantly lower (1.13±0.6, 1.83±0.7 respectively, \u0000p=0.002); the SDANN during HUTT (28.7±20.2, 18.2 ± 19.9 respectively, p=0.024) were significantly higher in the patients than the \u0000controls. \u0000Conclusion: Head-up tilt test positivity is frequent in epileptic children, and cannot be used in differential diagnosis. HRV calculated \u0000both from 24 hour Holter recordings and Holter recordings under orthostatic stress were impaired in favour of parasympathetic \u0000system in epileptic children.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44909070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of preemptive use of plerixafor on stem cell mobilization in patients with lymphoma and multiple myeloma","authors":"A. Uysal, M. Erkurt, Irfan Kuru, E. Kaya, İ. Berber, A. Sarici, S. Biçim, Ahmet Kaya, Emine Hidayet","doi":"10.5472/marumj.1244684","DOIUrl":"https://doi.org/10.5472/marumj.1244684","url":null,"abstract":"ABSTRACT \u0000Objective: The aim of this study is to investigate the effect of the preemptive use of plerixafor in patients with lymphoma and multiple \u0000myeloma which was administered as a preemptive single dose to the patients who were determined to have a CD34+ cell count of","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42080892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of angiotensin receptor-neprilysin inhibitor treatment on erectile dysfunction in heart failure with a reduced ejection fraction","authors":"S. Sert, E. Karabay, B. Gungor, O. Yildirimturk","doi":"10.5472/marumj.1244456","DOIUrl":"https://doi.org/10.5472/marumj.1244456","url":null,"abstract":"Objective: Erectile dysfunction (ED) is a common condition in patients with heart failure (HF), which impairs quality of life. Our \u0000study aimed to compare those patients, who received traditional treatment with a diagnosis of HF and those who received angiotensin \u0000receptor-neprilysin inhibitor (ARNI) treatment in addition to the current treatment, in terms of ED at the end of 6 months. \u0000Patients and Methods: The study was planned as a single-center, prospective study. The study included 200 patients with heart \u0000failure. The patients’ demographic, clinical, and echocardiographic characteristics were recorded, and an international ED scoring \u0000questionnaire was applied. The participants in the study were divided into two groups: those who received ARNI treatment and those \u0000who did not. After 6 months, the ED questionnaire was applied to the patients again and the groups were compared. \u0000Results: The median age of the patients was 53 (years). The median ejection fraction (EF) value was calculated to be 30% and no \u0000significant difference was found between the groups (p: 0.122). It was found that N-terminal pro-brain natriuretic peptide (NT-pro- \u0000BNP) levels measured at the end of the 6th month were significantly lower in patients who had received ARNI treatment than in those \u0000who had not (respectively, 245 pg/ml, 200 pg/ml; p: 0.003). In the analysis performed to detect the presence of ED, it was discovered \u0000that the ED score change was significantly higher in the group that had received 6 months of ARNI treatment (p: 0.031) compared to \u0000that in the group that had not (p: 0.031). When the ED sub-parameters were compared in terms of the 6-month change rate, it was \u0000found that the ARNI group had a significant increase in terms of ED and sexual satisfaction scores, but no significant difference was \u0000found in the other parameters (p: 0.001, p: 0.029). \u0000Conclusion: Erectile dysfunction is more common in patients with heart failure compared to the rest of society and impairs quality of \u0000life. In our study, it was determined that ED complaints decreased significantly in HF patients, who had received ARNI treatment for \u00006 months than in patients who had not.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70885350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular analysis of human adenoviral keratoconjunctivitis cases: Results of a 2-year survey","authors":"Ayfer Guner, Rabia Can Sarınoğlu, F. Aydin, S. Akkaya Turhan, M. Kuşkucu, A. E. Toker, Aysegul Karahasan Yagci","doi":"10.5472/marumj.1244369","DOIUrl":"https://doi.org/10.5472/marumj.1244369","url":null,"abstract":"Objective: This study aimed to determine the adenovirus genotypes and their epidemiological features between January 2018 and \u0000November 2019, in Istanbul, Turkey. \u0000Material and Methods: Conjunctival swab samples were obtained from patients who were clinically diagnosed with keratoconjunctivitis. \u0000Samples were screened with an Adeno Detector kit (Rapid Pathogen Screening, RPS Inc., South Williamsport, PA). Nucleic acid \u0000extraction and amplification were performed with the ADENOVIRUS ELITe MGB® kit in the ELITe In Genius instrument (Elitech \u0000Group, Torino, Italy). For subtyping of the strains, sequencing primers targeted the ‘Hypervariable Region 7’ (HVR-7) of the hexon \u0000gene were used. DNA sequence analysis (n:72) was performed with ABI PRISM® 3100 Genetic Analyzer (Applied Biosystems, USA), \u0000and subtyping was done by BLAST analysis. \u0000Results: The median viral load in the samples (n: 77) was 7 log10 copies/mL (IQR: 4.5-7.4 log10 copies/mL). The clinical finding score \u0000was found to be significantly higher in the high viral load group (Adenovirus DNA≥6 Log 10 copies/mL) than in the low viral load \u0000group (Adenovirus DNA","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48118102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are neighborhood characteristics associated with physical activity levels among school children?","authors":"Gülin Kaya, P. Ay, S. Hıdıroğlu","doi":"10.5472/marumj.1244381","DOIUrl":"https://doi.org/10.5472/marumj.1244381","url":null,"abstract":"Objective: The objective of this study was to determine the prevalence of insufficient physical activity (IPA) and neighborhood \u0000characteristics associated with it, among school children. The impact of sociodemographic characteristics and ownership of electronic \u0000devices on physical activity (PA) were also evaluated. \u0000Materials and Methods: This was a cross-sectional study carried out among 5-7th grade students attending schools and their parents. \u0000IPA was defined as having moderate-vigorous activity for 0.05). \u0000Conclusion: The prevalence of IPA is alarmingly high among school children. The impact of neighborhood characteristics on PA might \u0000be obscured since both variables were measured subjectively. Devices related information/communication technologies increase IPA; \u0000we need to find novel ways to use these devices for PA promotion. There is also a need to increase structured PA opportunities.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42179837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical students’ knowledge of the disease, frequency of depression, anxiety, stress symptoms, and related factors in the COVID-19 pandemic: A web-based questionnaire","authors":"Esra Çınar Tanrıverdi, M. Bayraktar, Suat Sincan, K. Kaşali, Y. Çayır, Mine Sahingoz, Z. Ozkurt","doi":"10.5472/marumj.1244747","DOIUrl":"https://doi.org/10.5472/marumj.1244747","url":null,"abstract":"Objective: In this study, it was aimed to determine the level of knowledge of medical students about coronavirus disease 2019 \u0000(COVID-19), to investigate the frequency of depression, anxiety, stress symptoms and related factors. \u0000Materials and Methods: The study is a cross-sectional study conducted with 904 volunteer medical students. Data were collected \u0000with an online questionnaire, including sociodemographic characteristics, knowledge about COVID-19, the Depression, Anxiety, and \u0000Stress Scale. \u0000Results: Mean age was 21.3±2.2 years, and 54% of them (n=488) were female. Fifty five percent (n=497) thought that their level \u0000of knowledge about COVID-19 was sufficient, and 94.6% (n=846) were concerned about the disruption of their education. Their \u0000knowledge level was found to be 15.09±2.43 points out of 23 points. The depression, anxiety and stress symptoms were found in \u000064.9%, 70.4% and 34.1% of participants, respectively. The risk of anxiety (OR=0.51, 95%CI=0.94, p=0.020) and depression (OR=0.95, \u000095%CI=1.15, p=0.025) were higher in women. Those with a high fear of transmitting the COVID-19 infection to their relatives had \u0000higher symptoms of depression, anxiety, and stress. (p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43725751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of mean platelet volume and red cell distribution width on prognosis in patients with myelodysplastic syndrome","authors":"Ihsan Ayhan, Ş. Ertop","doi":"10.5472/marumj.1244731","DOIUrl":"https://doi.org/10.5472/marumj.1244731","url":null,"abstract":"Objective: In this study, the relationship between changes in mean platelet volume (MPV) and erythrocyte distribution width (RDW) \u0000with hematological response and survival in patients with myelodysplastic syndrome was investigated. \u0000Patients and Methods: Between 1 January 2011 and 31 December 2018, patient characteristics and hemogram results were evaluated \u0000during the treatment process among 158 patients diagnosed with myelodysplastic syndrome. \u0000Results: The mean age of the patients who were included in the study was 71.53±12.6 years. The MPV percentage change in the 2-year \u0000follow-up of the patients with and without hematological response was significant, at 0.022±0.11 (2.2%) in those who responded and \u0000at 0.069±0.15 (6.9%) in those who did not (p=0.049). Throughout the same period, the degree of RDW changes in the patients who \u0000died was 13.23±22.97, the degree in those who survived was 2.86±21.42, and the difference between the two groups was statistically \u0000significant (p=0.006). \u0000Conclusion: In patients diagnosed with myelodysplastic syndrome, MPV and RDW values can be considered inexpensive and simple \u0000laboratory markers that can be used in follow-ups and promising tests to predict both treatment response and survival in the early \u0000period and change treatment modalities.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44113727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health behavior and health needs of first-year medical and health sciences students","authors":"Kamer Gur, Saime Erol, E. Gunes, Serap Çi̇fçi̇li̇, Burcu K CALIK, A. Ozer, I. Demirbuken, M. Polat, Çiğdem Apaydın Kaya","doi":"10.5472/marumj.1244398","DOIUrl":"https://doi.org/10.5472/marumj.1244398","url":null,"abstract":"Objective: The aim of this study is to evaluate the health behavior and health needs of medical and health sciences students in order \u0000to identify areas that need intervention. \u0000Materials and Methods: This descriptive study was conducted with 770 first-year university students. The data were collected with \u0000a sociodemographic questionnaire, the Youth Risk Behavior Survey and the Eating Attitudes Test. Body mass index was calculated. \u0000Results: Although, only 12.7% of the students were overweight or obese, 25.6% of the students perceived themselves to be overweight \u0000or obese. The students said that in the last week, 20.9% had breakfast 1 or 3 times, 5.7% ate no fruits at all, and 11.6% ate no vegetables \u0000at all. 48.1% of the students did not engage in any physical activity, and 83.2% spent more than 2 hours inactively in front of a screen. \u0000It was observed that 22.3% were current smokers. A propensity for eating behaviors disorder was found in 9.0%. Drinking energyboosting \u0000sports drinks 1-6 times in the last week (β: 3.286), smoking (β: 1.875) and eating few vegetable dishes in the last week (β: \u00000.484) were identified as factors that could be associated with a “tendency for eating behavior disorder.” \u0000Conclusion: We can conclude that nutritional issues, negative body weight perception, use of tobacco, and sedentary lifestyle are the \u0000main intervention and counselling areas for our study group.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43208219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Being a mother as a healthcare professional in the COVID-19 pandemic: A qualitative study","authors":"Nesibe Gunay Molu, Sadiye Sert, Neslihan Durmuşoğlu Saltali","doi":"10.5472/marumj.1244379","DOIUrl":"https://doi.org/10.5472/marumj.1244379","url":null,"abstract":"Objective: The aim of this research was to determine the changes in relationships between healthcare professional mothers and their\u0000preschool-aged children during the coronavirus disease 2019 (COVID-19) pandemic. In addition, the second objective of this study\u0000was to propose a new phenomenon that explains “being a mother as a healthcare professional” during the COVID-19 pandemic.\u0000Materials and Methods: The participants of the research were 16 healthcare professional mothers (8 doctors and 8 nurses) who had\u0000worked in intensive care units during the COVID-19 pandemic and had a preschool-aged child. The research was conducted in\u0000accordance with the phenomenological approach, one of the qualitative research designs. The research data were obtained through\u0000face-to-face interviews between the researchers and the participants using half-structured interview forms prepared by the researchers.\u0000Colaizzi’s 7-step method was used for evaluation of the data.\u0000Results: According to the research findings, the phenomenon of “being a mother as a healthcare professional” was gathered under\u0000four main themes: emotional reactions, new normal in life, difficulties that pandemic brought in life and coping strategies with these\u0000difficulties.\u0000Conclusion: The findings showed that the COVID-19 pandemic caused many changes in the lives of healthcare professional mothers\u0000and their children; these mothers and children built some emotional reactions, and they developed various strategies to overcome\u0000these emotional reactions.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48767276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}