Fatih BESIROGLU, Murat SUNBUL, Beste OZBEN, Ilker YAGCI, Jeyhun MAMMADOV, Nurten SAYAR, Altug CINCIN, Kursat TIGEN, Osman YESILDAG, Yelda BASARAN
{"title":"The effect of cardiac rehabilitation on left ventricular diastolic functions assessed by exercise stress echocardiography in patients with acute coronary syndrome","authors":"Fatih BESIROGLU, Murat SUNBUL, Beste OZBEN, Ilker YAGCI, Jeyhun MAMMADOV, Nurten SAYAR, Altug CINCIN, Kursat TIGEN, Osman YESILDAG, Yelda BASARAN","doi":"10.5472/marumj.1378522","DOIUrl":"https://doi.org/10.5472/marumj.1378522","url":null,"abstract":"Objective: The aim of our study is to investigate the impact of cardiac rehabilitation on left ventricular (LV) diastolic function in acute
 coronary syndrome (ACS) patients.
 Patients and Methods: Patients were selected consecutively among ACS patients who underwent primary percutaneous intervention
 and were found eligible for cardiac rehabilitation program from May 2014 to May 2015. Forty-four patients were included in cardiac
 rehabilitation group and recruited to 30 sessions of Phase-3 cardiac rehabilitation program six weeks after discharge. Twenty
 consecutive patients were included as control group. LV diastolic functions were assessed by resting and stress echocardiography.
 Results: There were not any significant differences in characteristics between the groups. Resting and stress E velocities and resting
 lateral e’ velocity significantly increased after rehabilitation program. Left atrial volume index, resting and stress A velocities and
 average E/e’ ratios were significantly lower while stress lateral e’ velocity was significantly higher in rehabilitation group after program
 compared to controls. The number of patients with diastolic dysfunction decreased after rehabilitation program. Final resting and
 stress echocardiography revealed significantly lower frequency of diastolic dysfunction in rehabilitation group.
 Conclusion: Cardiac rehabilitation improves diastolic functions in ACS patients, which may be detected by stress echocardiography.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136383671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Social media use in adolescent girls with depression: The relationship between social media use purposes, lack of social support, and cyber victimization","authors":"Muhsine Göksu, Ayşe Rodopman Arman, Ümmügülsüm Gündoğdu, Funda Gümüştaş","doi":"10.5472/marumj.1379988","DOIUrl":"https://doi.org/10.5472/marumj.1379988","url":null,"abstract":"Objective: Our study examined the relationship between purpose of social media use, perceived social support, and cyberbullying among adolescent girls with or without major depressive disorder (MDD). Patients and Methods: Fifty-two adolescent girls aged 13-18 years with a diagnosis of MDD were recruited. The control group consisted of 51 adolescents who were matched for age and gender. The adolescents completed a sociodemographic form, the Childhood Depression Inventory (CDI), the Social Media Attitude Scale (SMAS), the Cyberbullying Scale (CBS), and the Social Support Appraisal Scale for Children (SSAS). Results: Social media use was significantly higher among adolescent girls with MDD (P","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":"47 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139358651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endogenous maternal serum preimplantation factor levels in earlyonset preeclamptic pregnancies","authors":"Muhammet Atay OZTEN, Ece KARACA","doi":"10.5472/marumj.1229910","DOIUrl":"https://doi.org/10.5472/marumj.1229910","url":null,"abstract":"Objective: Preimplantation-factor (PIF) is a new peptide with many potential functions. We aimed to compare the maternal serum PIF levels among early-onset preeclamptic patients with the healthy controls at the same gestational age. Patients and Methods: Thirty-nine early-onset preeclamptic (< 34 gestational weeks) patients and 45 healthy expecting women have been added to our study. Patients with or suspicion of any chronical maternal disease, gestational diabetes, twin pregnancies, fetal or placental anomalies or any other obstetric complications have been excluded. Competitive enzyme-linked immunosorbent assay (ELISA) (Elabscience Biotechnology Co., Texas, USA) has been used to analyze the PIF levels in the collected samples. Gestational age, maternal age, gravida, parity, fetal growth, body mass index (BMI), maternal weight and height, plasma PIF levels have been collected/measured and analyzed in both groups. Results: The primary outcome of our study –the Preimplantation Factor- was significantly higher in study group than the healthy controls (100.36 ± 41.92 vs. 83.14 ± 51.27 p=0.016). Conclusions: We have found the PF levels statistically higher in the study group. PIF levels might have a role in the progression and pathogenesis of the preeclamptic patients. Further studies with larger groups have to be planned and performed to resolve the real relation between PIF and preeclampsia.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135195820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is subclinical hypothyroidism a risk factor for gestational diabetes mellitus?","authors":"H. Şen Selim, M. Sengul","doi":"10.5472/marumj.1302525","DOIUrl":"https://doi.org/10.5472/marumj.1302525","url":null,"abstract":"Objective: Gestational diabetes mellitus is characterized by increased blood sugar that first appears during pregnancy. Multiple articles \u0000have described a relationship between hypothyroidism/subclinical hypothyroidism (SCH) and a rise in the risk of concomitant \u0000pregnancy complications, including gestational diabetes mellitus (GDM), but the effect of SCH on pregnancy is uncertain in the \u0000literature. We clarified the contribution of SCH to GDM development. \u0000Patients and Methods: We conducted a retrospective study. From the patient records, the first 250 pregnant women who applied to our \u0000hospital for screening at 20-24 weeks and had glucose tolerance tests were included in our study. Retrospectively, all these pregnant \u0000women’s first-trimester thyroid-stimulating hormone (TSH) levels were recorded. We created two groups according to the oral glucose \u0000tolerance test (OGTT) results: a case group diagnosed with GDM and a control group with average blood glucose. Their first-trimester \u0000TSH levels were compared between the two groups and defined whether they had euthyroid, subclinical hypothyroidism (TSH=2.5- \u00005.5mIU/L) or overt hypothyroidism (TSH >5.5). \u0000Results: We diagnosed 37 of 191 patients (19.4%) with GDM. When we checked the case and control groups, the mean TSH of the \u0000GDM group was 1.8 mIU/L, and the control group was 1.7 mIU/L, but the difference was not statistically significant (p=0.121). 24.32% \u0000(n=9) of 37 pregnant women with GDM were diagnosed with subclinical hypothyroidism/hypothyroidism; this rate was as low as \u000014.93% (n=28) in the non-GDM group, but no statistical difference was found (p=0.21). \u0000Conclusion: It can be predicted that other accompanying factors may be the primary determinant in the development of GDM rather \u0000than subclinical hypothyroidism. Risk scales that include the first trimester TSH level should be established for the development of \u0000GDM.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48781550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"T1 relaxation time in the evaluation of liver fibrosis; with native MR relaxometry","authors":"Firathan Sarialtin, H. Yiğit, E. Ergun, P. Koşar","doi":"10.5472/marumj.1302518","DOIUrl":"https://doi.org/10.5472/marumj.1302518","url":null,"abstract":"Objective: Non-invasive methods have been investigated as an alternative to biopsy in assessing liver fibrosis. This study aimed to \u0000evaluate the relationship between liver T1 relaxation time and liver fibrosis as a non-invasive alternative method. \u0000Patients and Methods: This study analyzed 1.5T magnetic resonance (MR) images of 86 patients retrospectively. The participants were \u0000divided into two groups: patients with chronic hepatitis and the control group. Native variable flip angle (VFA) T1 mapping technique \u0000was used to estimate liver T1 relaxation time. T1 mapping sequence, T2* mapping sequence, and image analysis were performed. The \u0000liver size, the spleen size, the liver T1 relaxation time, and the liver T2* relaxation time were recorded. \u0000Results: The T1 relaxation time was 758.4 ± 121.1 ms in the chronic hepatitis group and 600.2 ± 67 ms in the control group. The T1 \u0000relaxation time of the patient group was significantly higher than that of the control group (p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49367206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood pressure and heart rate in aripiprazole once – monthly and paliperidone 1 and 3-month long-acting preparations","authors":"G. Sarıdoğan, M. Goren","doi":"10.5472/marumj.1302445","DOIUrl":"https://doi.org/10.5472/marumj.1302445","url":null,"abstract":"Objective: This study aims to evaluate the blood pressure and heart rates of the patients treated with aripiprazole once-monthly, \u0000paliperidone 1-month, and paliperidone 3-month long-acting injections. \u0000Patients and Methods: This study was a non-invasive observational study. Subjects using the same long-acting injection preparation \u0000for at least four months without skipped injections were assigned to 3 groups according to their treatments. They were screened \u0000starting from routine injection day and monthly for four months. Heart rate, systolic blood pressure, and diastolic blood pressure were \u0000recorded for each subject. \u0000Results: Systolic and diastolic blood pressure among the three treatment groups demonstrated no statıstıcal significance. The heart rate \u0000of the paliperidone 3-month group was significantly higher than the aripiprazole once-monthly group. However, the mean heart rate \u0000was within the physiological limits. Thus, a clinical significance can hardly be attributed. \u0000Conclusion: Aripiprazole once-monthly, paliperidone 1-month, and paliperidone 3- month long-acting injections are non-inferior \u0000regarding heart rate, systolic and diastolic blood pressure during the maintenance treatment.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42592402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. S. Koca, Y. Çelik, H. Keskin, Pinar YALCIN BALCIK
{"title":"The factors affecting the QoL among women during the postpartum period","authors":"G. S. Koca, Y. Çelik, H. Keskin, Pinar YALCIN BALCIK","doi":"10.5472/marumj.1302417","DOIUrl":"https://doi.org/10.5472/marumj.1302417","url":null,"abstract":"Objective: As healthcare has become increasingly patient-centered, outcomes such as disease-specific quality of life (QoL) have become \u0000increasingly important. This study aimed to determine the factors affecting the QoL of postpartum women and which factors make a \u0000difference and affect the QoL. \u0000Patients and Methods: The Euro QoL 5 Dimension 5 Level (EQ 5D-5L) scale was used to measure the health-related QoL of postpartum \u0000women. A total of 175 postpartum mothers participated in this study. \u0000Results: The QoL of women differed in age, delivery type, venous thromboembolism risk factors, parity, gravida, number of live \u0000births, and use of anticoagulant medication. According to multiple regression analyses, the “age” variable had a significant effect \u0000on the QoL. However, the variables of education, social security, employment status, and monthly income of the family were not \u0000significant determinants of QoL. Also, the “number of live births” variable did not significantly affect the QoL, other obstetric and \u0000clinical variables had a significant effect on the QoL. The gravida increased the QoL but the number of miscarriages and the venous \u0000thromboembolism risk score decreased the QoL. \u0000Conclusions: This study shows that, the QoL of women varies according to obstetric, socio-demographic, and clinical factors, and “age, \u0000gravida, the number of abortions and the venous thromboembolism risk score” variables have a significant effect on the QoL.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45928541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Mercanci, C. Ilgın, Ş. Olgun Yıldızeli, D. Kocakaya, B. Balcan, Buket Erturk Sengel, S. Karakurt, E. Eryuksel
{"title":"Increased D-dimer is associated with disease progression and increased mortality in Turkish COVID-19 patients","authors":"Z. Mercanci, C. Ilgın, Ş. Olgun Yıldızeli, D. Kocakaya, B. Balcan, Buket Erturk Sengel, S. Karakurt, E. Eryuksel","doi":"10.5472/marumj.1302440","DOIUrl":"https://doi.org/10.5472/marumj.1302440","url":null,"abstract":"Objective: Coagulopathy is thought to play an important role in the development of severe COVID-19. High D-dimer levels have been \u0000reported in Chinese cohort studies. However, ethnicity has significant implications for thrombotic risk. Our aim in this study is to \u0000determine the effect of D-dimer measurements on disease prognosis and mortality in Turkish patients with COVID-19. \u0000Patients and Methods: The study was designed retrospectively. Patients over the age of 18 who were admitted to our hospital were \u0000included in the study. \u0000Results: The study included 226 patients. According to the World Health Organization staging, 75(33.2%) patients, according to the \u0000staging of Siddiqi et al., 67 (29.7%) patients progressed. In the ROC analysis performed to predict mortality, AUC value for D-dimer \u0000was found to be 82.25% (95%CI 74.8%-89.71%). When the cut-off value for D-dimer was accepted as ≥3.25mg/L, specificity was \u000094.15%, correctly classified rate 88.5%, positive likelihood ratio as (LR):5.69, negative LR:0.71. \u0000Conclusion: As a result, similar to the Chinese cohorts, elevated D-dimer measurements increase disease progression and mortality \u0000in Turkish patients with COVID-19. D-dimer levels of 3.25 mg/L and above, strongly determine the risk of increased mortality in the \u0000Turkish Caucasian ethnic group.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47632853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is neurofibromatosis type 1 diagnosed in every patient who presents with café au lait macules? A single-center experience","authors":"N. Eker, A. Tokuç, Burcu TAS TUFAN, E. Şenay","doi":"10.5472/marumj.1302264","DOIUrl":"https://doi.org/10.5472/marumj.1302264","url":null,"abstract":"Objective: Neurofibromatosis type 1 (NF1) is the most common hereditary neurocutaneous syndrome. The most crucial morbidity of \u0000NF1 is tumors that may develop. Cases with café-au-lait macules (CALMs) which is the first clinical finding of NF1, due to the anxiety \u0000of its associated morbidity, are referred to the pediatric oncology clinic. In this study, we aimed to examine the characteristics of the \u0000patients who applied to our outpatient clinic with CALMs. \u0000Patients and Methods: The data of 157 pediatric patients who applied to our institution with the diagnosis of CALMs between June \u00002010 and November 2020 were analyzed retrospectively. \u0000Results: There were 157 pediatric cases referred to us for CALMs. According to the National Institutes of Health (NIH) diagnostic \u0000criteria, 109 (69.4%) cases were diagnosed with NF1. The diagnosis of 22 cases with NF1 were supported by genetic examination. \u0000Optic glioma was detected in 39 (24.8%) cases. In 15 (38.4%) of cases with optic glioma, visual functions were also affected. Second \u0000diagnostic criterion did not develop during the follow-up period, except for macules, in 48 cases (30.5%). \u0000Conclusion: In cases with multiple CALMs, the probability of NF1 diagnosis is high, and close and regular follow-up is of great \u0000importance in catching the development of the second clinical criterion and minimizing its morbidity.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43018331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ben Azir Begum Hymabaccus, R. T. Doğrul, C. Balcı, Cemile Ozsurekci, H. Çalışkan, E. Karabulut, M. Halil, M. Cankurtaran, Burcu Balam Doğu
{"title":"An effective and practical tool to assess physical frailty in older adults: Turkish validation of the FRAIL scale","authors":"Ben Azir Begum Hymabaccus, R. T. Doğrul, C. Balcı, Cemile Ozsurekci, H. Çalışkan, E. Karabulut, M. Halil, M. Cankurtaran, Burcu Balam Doğu","doi":"10.5472/marumj.1297696","DOIUrl":"https://doi.org/10.5472/marumj.1297696","url":null,"abstract":"Objective: Practical scales with tested validity and reliability are needed to clinically determine frailty.The aim of this study is to find \u0000out whether the Fatigue, Resistance, Ambulation, Illnesses, and Loss of weight (FRAIL) scale is an effective screening scale to show \u0000frailty \u0000Patients and Methods: The Frail non-Disabled (FIND) scale validated in the Turkish population was applied for FRAIL scale validation. \u0000Comprehensive geriatric assessment and Fried Index were performed on 85 outpatients who were 65 years and older. The patients were \u0000examined in terms of comorbidity, number of falls, living environment, number of drugs used, and hospitalization in the last year. \u0000Results: The FRAIL scale had a high correlation with the FIND scale and Fried Index (correlation coefficients are 0.956 and 0.934, \u0000respectively).In addition, it was found to be associated with Activities of Daily Living (ADL),Instrumental Activities of Daily Living \u0000(IADL) scales,the Mini-Mental State Examination (MMSE),Yesavage Geriatric Depression Scale (GDS),Mini Nutritional Assessment \u0000short-form (MNA-sf),Clock Drawing Test (CDT),handgrip strength, and timed up and go test(p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44630599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}