{"title":"Congenital cytomegalovirus infection cases and follow-up findings in Antalya, Turkey","authors":"Zubeyde ERES SARITAS, Bilal Olcay PEKER, Dilek ÇOLAK, Imran SAGLIK, Rabia Can SARİNOĞLU, Murat TURHAN, Aslı BOSTANCI TOPTAŞ, Derya MUTLU, Gözde ÖNGÜT, Nihal OYGUR, Munire ERMAN","doi":"10.5472/marumj.1367753","DOIUrl":"https://doi.org/10.5472/marumj.1367753","url":null,"abstract":"Objective: To investigate the presence of cCMV infection and the CMV-DNA virus in the newborns who applied for newborn hearing
 screening test (NHST) and CMV-DNA viruria with physical, mental-motor development and hearing status of cCMV cases in the
 second year of age.
 Patients and Methods: CMV-DNA was investigated in 1150 newborns’ oral swabs (0-21 days) by polymerase chain reaction kit and
 urine of patients with positive CMV-DNA in saliva. Transient Evoked Otoacoustic Emission test was performed for NHST.
 Results: CMV-DNA was posititve in saliva of 38 (3.3%) newborns and urine of 10 out of 37 newborns. The prevalence of cCMV
 was 0.87% (95% CI=0.697-1.042). All newborns passed the NHST. In newborns with cCMV:jaundice in 60% (6/10), low birthweight
 in 40% (4/10), small for gestational age in 50% (5/10) of them. Jaundice was the most significant variable (P","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135132656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Huge thrombosed popliteal artery aneurysm","authors":"Elif DEMIRBAS, Koray AK","doi":"10.5472/marumj.1368353","DOIUrl":"https://doi.org/10.5472/marumj.1368353","url":null,"abstract":"Popliteal artery aneursyms (PAA) are the most common true peripheral aneurysm. We report a case of 66-year-old patient who has
 pulsatile mass posterior of the right knee diagnosed with massive PAA.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135132389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between smartphone and computer games and anger in adolescents","authors":"Suat TUNCAY, Abdullah SARMAN","doi":"10.5472/marumj.1367799","DOIUrl":"https://doi.org/10.5472/marumj.1367799","url":null,"abstract":"Objective: In this study, it was aimed to determine the relationship between the causes and duration of gaming and types of games and
 levels of anger among Turkish adolescents studying at high schools.
 Materials and Methods: The study was conducted using a cross-sectional descriptive design with adolescents enrolled in high schools
 in an Eastern Turkish province. A total of 819 adolescent students aged 13-18 were included in the study. Data were collected online
 through Google Forms, utilizing both the “Sociodemographic Form” and the “Adolescent Anger Rating Scale.”
 Results: The mean age of the adolescents was 15.52±1.29. Gender, academic performance, daily sleep duration, and daily walking
 distance were not found to be associated with anger levels. Additionally, there was no significant correlation between anger scores and
 the status of computer and smartphone usage. However, individuals who used smartphones for 3 hours or more for purposes such as
 gaming, entertainment, chatting, messaging, and socializing exhibited higher anger scores.
 Conclusion: Academic grades, the duration of smartphone usage, computer and smartphone use for gaming/entertainment, chatting,
 messaging, and socializing were found to be associated with anger. Specifically, extended periods of playing war, fighting, and similar
 games on both computers and smartphones were correlated with higher levels of anger. It would be advantageous for parents to monitor
 and regulate the content of the games their adolescents play, observe any behavioral differences, and take necessary precautions.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135132528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Compressive external bracing in pectus carinatum : Results of the first 100 patients","authors":"Nezih Onur ERMERAK","doi":"10.5472/marumj.1367999","DOIUrl":"https://doi.org/10.5472/marumj.1367999","url":null,"abstract":"Objective: Pectus carinatum is the second most common chest wall deformity causing psychological problems. There has been a
 growing interest in the conservative treatment of the disease in recent years. Here, we present results of the first 100 patients who were
 treated with compressive external bracing therapy.
 Patients and Methods: A total of one hundred patients who were treated with compressive external bracing between 2017-2023
 were reviewed from database. Parameters recorded include demographics, type of the deformity, duration of the treatment time,
 complications, and patient satisfaction.
 Results: Among 100 patients 88 were male (88%) and 12 were female (12%) and the mean age was 13.3 years (3-19). 76 patients (76%)
 had a symmetric pectus carinatum and 24 patients (24%) had asymmetric. 23 (23%) patients had scoliosis, 9 (9%) had kyphosis, 1 (1%)
 had Poland Syndrome and 1 (1%) patient had Marfan Syndrome as accompanying anomalies. Quality of Life Questionnaire revealed
 94.8 % satisfaction in patients who completed the treatment.
 Conclusion: Compressive external bracing is associated with satisfactory results in the treatment of pectus carinatum. This nonsurgical
 intervention enables us to treat more patients in younger ages with lesser comorbidity than surgical intervention.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135132686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Halim ULUGOL, Melis TOSUN, Ugur AKSU, Esin ERKEK, Pinar GUCLU, Murat OKTEN, Fevzi TORAMAN
{"title":"Monitoring tissue perfusion during extracorporeal circulation with laser speckle contrast imaging","authors":"Halim ULUGOL, Melis TOSUN, Ugur AKSU, Esin ERKEK, Pinar GUCLU, Murat OKTEN, Fevzi TORAMAN","doi":"10.5472/marumj.1368021","DOIUrl":"https://doi.org/10.5472/marumj.1368021","url":null,"abstract":"Objective: The laser speckle contrast imaging (LSCI) system is a method to evaluate microcirculation. The primary aim of our study
 is to evaluate the relationship between LSCI and perfusion markers in coronary artery bypass grafting (CABG). Our second aim is to
 investigate the relationship between LSCI and extubation time in the intensive care unit.
 Patients and Methods: Fifteen patients aged 43-80 years who will undergo on-pump CABG were included in the prospective study.
 Mean arterial pressure (mmHg), heart rate (min-1), PO2 (mmHg), PCO2 (mmHg) and lactate (mmol/L) levels were measured preinduction,
 post-induction, 10th minute of the extracorporeal circulation, post-crossclamp, and post-operatively. At the same time
 points, LSCI values from the skin were measured and recorded. The intubation times of the patients were also recorded.
 Results: There was no significant change in systemic tissue perfusion markers (P>0.05). LSCI perfusion values decreased significantly
 from induction and remained low until the end of surgery (P","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135132687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic utility of the systemic immune-inflammatory index in preterm neonates with late-onset sepsis","authors":"Gonca VARDAR, Eren ÖZEK","doi":"10.5472/marumj.1367904","DOIUrl":"https://doi.org/10.5472/marumj.1367904","url":null,"abstract":"Objective: To assess if systemic immune-inflammatory index (SII) has a diagnostic role for late-onset sepsis (LOS) in premature
 neonates.
 Patients and Methods: A single-center retrospective observational study including preterm infants with culture-proven LOS and
 controls was conducted between January 2017 and December 2022. SII was derived using complete blood count values acquired at the
 beginning of and three to five days before LOS. SII was compared between the LOS group and controls.
 Results: A total of 144 infants were included in the study. The SII values of the LOS group were found to be significantly increased in
 comparison to the control group [376.74 (11.11 – 15170) vs. 235.24 (46.83 – 1214.38) (median, min-max), P =0.018]. The SII values
 significantly increased when pre-sepsis and LOS values were compared [200.6 (0 – 1295.78) vs. 328.28 (0 – 14678, P","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135132692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yavuz ŞAHBAT, Tolga ONAY, Ömer SOFULU, Oytun Derya TUNC, Elif Nur KOÇAK, Bulent EROL
{"title":"Delayed surgical treatment of geriatric hip fractures increases the need for intensive care unit, morbidity and mortality rates","authors":"Yavuz ŞAHBAT, Tolga ONAY, Ömer SOFULU, Oytun Derya TUNC, Elif Nur KOÇAK, Bulent EROL","doi":"10.5472/marumj.1367987","DOIUrl":"https://doi.org/10.5472/marumj.1367987","url":null,"abstract":"Objective: The aim of this study was to present the intensive care admission, morbidity and mortality rates of older adults with hip
 fractures who could not be operated in the first 48 hours after admission, which is the recommended time in literature.
 Patients and Methods: Patients aged >60 years of age with a hip fracture who were operated on in our clinic between January 2012
 and June 2021 were identified. The patients were evaluated in 3 groups according to preoperative waiting time, as Group 1: 2-10 days,
 Group 2: 11-20 days, and Group 3: ≥21 days.
 Results: Mortality within 1 year was found to be 20% in Group 1, 31% in Group 2, and 50% in Group 3 (P=0.001). Preoperative waiting
 time did not affect complications related to surgery infection (P=0.890), implant failure (P=0.129) but surgeons had to deal with
 decubitus ulcer (P=0.016) and urinary tract infection (P=0.001). Patients with a long preoperative waiting time required preoperative
 intensive care (P=0.003).
 Conclusion: The study results demonstrate that as the preoperative waiting period increases, the mortality rate also increases, the need
 for intensive care before and after the operation increases, and there is increased morbidity due to a long hospital stay.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wearable technology data-based sleep and chronic disease relationship","authors":"Suayip BIRINCI","doi":"10.5472/marumj.1367367","DOIUrl":"https://doi.org/10.5472/marumj.1367367","url":null,"abstract":"Objective: The aim of the study was to examine the cross-sectional relationship between sleep duration and 12 chronic diseases
 (obesity risk, diabetes, asthma, renal failure, hypertensive diseases, chronic obstructive pulmonary disease, cardiovascular diseases,
 ischaemic heart disease, pulmonary heart disease, immunodeficiencies and immune system disorders) by transferring the data to the
 national electronic patient record system through wearable device technology.
 Materials and Methods: The data of the study were obtained from the Ministry of Health “Turkey National Personal Health Record
 System” (The “e-Nabız”). Between 30.03.2023 and 28.05.2023, 315448 data from 27847 people (15167 male) were collected and
 analysed on the basis of province, rural status, age group, gender and presence of chronic diseases and average, minimum (min),
 maximum (max) sleep duration. Descriptive statistics, chi-square analysis, Independent Samples t-Test, One-way Analysis of Variance
 and Pearson’s correlation coefficient were used.
 Results: The max. and average sleep duration were significantly shorter in men. Max. sleep duration decreased while the average sleep
 duration increased with increasing age. Participants with asthma, chronic renal failure and cerebrovascular diseases had decreased
 average sleep duration. The frequency of those who slept for 7-8 hours, which is the ideal sleep duration, is lower in all chronic diseases.
 Conclusion: Most of the common chronic diseases may affect the sleep duration times and quality, which may further affect the
 prognosis of these patients.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of chiral switch on drug labeling in Turkey: indication, posology, and adverse effects","authors":"Neriman Ipek KIRMIZI SONMEZ, Caner VIZDIKLAR, Volkan AYDIN, Onur GULTEKIN, Ayfer BAHAR, Ahmet AKICI","doi":"10.5472/marumj.1368074","DOIUrl":"https://doi.org/10.5472/marumj.1368074","url":null,"abstract":"Objective: Chiral switch, which involves replacing racemic drugs to market them as pure enantiomers, is presumed to improve efficacy
 and safety. Data on how chiral switch-related changes are represented in summary of product characteristics (SmPC) is scarce. We
 aimed to compare the indication, posology, and safety expressions in SmPCs of racemates and their pure enantiomers.
 Materials and Methods: We examined SmPCs of nine drug pairs (racemate/pure enantiomer) that underwent chiral switching among
 top 100 utilized active substances throughout Turkey. We evaluated the expressions in “indications”, “posology”, and “adverse effects”
 (AE) subheadings. Daily doses were examined based on “Defined Daily Dose” (DDD) metric.
 Results: We detected indication differences in four drug pairs, including absence of “peptic ulcer” in dexlansoprazole and “prevention
 of depression relapses” in escitalopram. DDDs of pure enantiomers decreased in most of the pairs. Recommended daily doses of
 esomeprazole and dexibuprofen per DDD were lower than their racemates. Cautions about use in renal and/or hepatic insufficiency
 varied in three pairs. AE expressions differed in seven drug pairs, mainly citalopram/escitalopram.
 Conclusion: This study demonstrated few indication differences in SmPCs of the drug pairs frequently used in Turkey and underwent
 chiral switching. However, dose reductions and distinctions in safety expressions were remarkable.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hayati KART, Abdullah DEMIRTAS, Mehmet Esat UYGUR, Fuat AKPINAR
{"title":"Innovative distal bolt-locking screw tibial nailing method and conventional nailing: A comparison of outcomes","authors":"Hayati KART, Abdullah DEMIRTAS, Mehmet Esat UYGUR, Fuat AKPINAR","doi":"10.5472/marumj.1368036","DOIUrl":"https://doi.org/10.5472/marumj.1368036","url":null,"abstract":"Objectives: Distal bolt-locking screw (DSBLS) tibial nailing offers an innovative method in which the nail is locked upon entering the
 screw. The current study compares the clinical, radiological, and functional outcomes of DSBLS tibial nails with conventional tibial
 nails.
 Patients and Methods: We retrospectively evaluated 38 tibial fractures of 37 patients treated with intramedullary nailing. In Group
 1, 21 fractures were treated with DSBLS nailing, while in Group 2, 17 fractures were treated with conventional nailing. Duration of
 surgery, time to weight-bearing, time to union, presence of deformity, return to work and sports, complications, American Orthopedic
 Foot and Ankle Society Score (AOFAS) and Olerud-Molander Ankle Score (OMAS) values were compared between the groups.
 Results: Group 1 patients had significantly shorter time to full weight-bearing than patients in Group 2 (P=0.032). There was no
 significant difference between the groups in functional comparisons according to the AOFAS. In contrast, the outcomes of Group 2
 were better than those of Group 1 according to the OMAS (P=0.475 and P=0.037). The outcomes for the other variables were similar.
 Conclusion: In this method, patients can bear weight in a shorter time. The results of DSBLS nailing are as good as conventional nails,
 and it can be safely preferred in treating tibial fractures with intramedullary nailing.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}