Ceska Gynekologie-Czech Gynaecology最新文献

{"title":"Sister Mary Joseph's nodule - rare umbilical cutaneous metastasis.","authors":"Markéta Polková, Pavel Kabele, Peter Koliba, Tadios Mekonnen Asres, Olga Dubová, Tomáš Brtnický, Michal Zikán","doi":"10.48095/cccg2025154","DOIUrl":"10.48095/cccg2025154","url":null,"abstract":"<p><p>This is a short review about a rare metastatic physical finding of abdomino-pelvic malignancies that is called Sister Mary Joseph's nodule. It is cutaneous metastasis in the umbilical region and it was first used almost 200 years ago. Even though it is a rare finding, we should not forget it in the differential diagnosis of umbilical nodules. The article also includes two case reports.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 2","pages":"154-157"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the epidemiologic, clinical, laboratory, ultrasonographic, and anatomopathological profile of women with hydatidiform mole at two referral centers in Northeastern Brazil.","authors":"Eveline Valeriano Moura Linhares, Francisco Edson de Lucena Feitosa, Antonio Braga, Edward Araujo Júnior, Evelyn Traina, Cecília Maria Ponte Ribeiro, Sue Yazaki Sun","doi":"10.48095/cccg2025129","DOIUrl":"https://doi.org/10.48095/cccg2025129","url":null,"abstract":"<p><strong>Objective: </strong>To determine the profile of women undergoing uterine evacuation for suspected hydatidiform mole (HM) according to their clinical, laboratory, ultrasound, and anatomopathological characteristics at two referral centers in Northeastern Brazil.</p><p><strong>Methods: </strong>Retrospective cohort study was performed in two referral centers between October 2016 and December 2022 with women undergoing uterine evacuation for suspected HM. Socio-demographic characteristics, clinics, biochemistry, ultrasound, anatomopathology, and outcome were evaluated.</p><p><strong>Results: </strong>A total of 507 women were admitted with clinical suspicion of gestational trophoblastic disease, of which 334 were confirmed, with 107 being in Center-1 and 227 being in Center-2. Mean distance between the referral center and the patient's home was 88 km. Mean age of the women was 27 ± 9 years, with a predominance of 19 to 39 years (72%), and approximately 60% of the cases were diagnosed ≤ 12 weeks of gestation. Vaginal bleeding was observed in 79% of women. Transvaginal ultrasound showed a typical appearance in 90% of the examinations. The macroscopic aspect was described as a vesicle in 70% of cases. Uterine evacuation was mainly performed by uterine curettage (43%). The majority of women had no complications (69%). The outcome considered to be remission was achieved in 37.1% of cases, but 38.9% abandoned follow-up, and 9% did not start follow-up after hospital discharge.</p><p><strong>Conclusion: </strong>The distance traveled by women to the referral centers was significant, but the majority of women had no complications. Remission was observed in 37.1% of women, but there was a high abandonment rate of 38.9%.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 2","pages":"129-140"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic management of ovarian torsion at 26 weeks of gestation.","authors":"İbrahim Kale, Cem Yalçınkaya, Gülten Merve Özalp Çelikçi","doi":"10.48095/cccg2025395","DOIUrl":"10.48095/cccg2025395","url":null,"abstract":"<p><strong>Objective: </strong>We report a case of ovarian torsion at 26 weeks of gestation that was successfully managed laparoscopically.</p><p><strong>Case report: </strong>A 29-year-old woman at 26 weeks of pregnancy presented to the emergency department with left lower quadrant pain. Ultrasound examination revealed a 64 × 60 mm cyst in the left ovary, and Doppler imaging could not detect blood flow in the left ovary. The patient was diagnosed with left ovarian torsion and subsequently underwent laparoscopic left ovarian detorsion and cystectomy. The patient experienced no postoperative surgical or obstetric complications and had an uncomplicated vaginal delivery at 39 weeks of gestation.</p><p><strong>Conclusion: </strong>In the surgical management of adnexal torsion during pregnancy, laparoscopy can be safely performed not only in the 1st and 2nd trimesters but also in the 3rd trimester, provided that adequate surgical expertise and appropriate equipment are available.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 5","pages":"395-397"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes mellitus and pregnancy, how to analyze national individual-level data.","authors":"Jitka Jírová, Kateřina Anderlová, Hana Krejčí, Vratislav Krejčí, Patrik Šimják, Lenka Szczuková, Jiří Jarkovský, Antonín Pařízek","doi":"10.48095/cccg2025366","DOIUrl":"https://doi.org/10.48095/cccg2025366","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to present the methodological framework and analytical approaches for utilizing national individual-level data on diabetes mellitus in pregnancy, a condition that poses a significant risk to the health of both mother and child.</p><p><strong>Materials and methodology: </strong>The National Health Information System serves as the central repository for data on the Czech healthcare system. Through the integration of various recorded datasets, it enables detailed analysis of the incidence of diabetes mellitus in connection with pregnancy, provided that an appropriate analytical algorithm is applied. The input dataset for the analysis consisted of births recorded between 2012 and 2023 in the National Register of Reproductive Health, specifically the Mothers module. In total, 1,240,227 births were included in the analysis. For each case, the presence of the disease was verified using records from the National Register of Reimbursed Health Services.</p><p><strong>Results and conclusion: </strong>Based on the defined criteria, including specific medications, reported medical procedures, medical devices, and disease diagnoses, the prevalence of diabetes mellitus among parturient women was determined to be 15.4%. Thanks to the interconnected structure of the National Health Information System and newly established definition of a pregnant woman with diabetes, it will be possible to continue analyzing the prevalence and health impacts of this condition at the national level.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 5","pages":"366-372"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of the Endometriosis Health Profile-30 questionnaire in women aged 18- 30 years in the Czech Republic.","authors":"Ingrid Palaščáková Špringrová, Martin Němec, Martina Kadlecová","doi":"10.48095/cccg2025380","DOIUrl":"https://doi.org/10.48095/cccg2025380","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the study is to obtain valid data on the quality of life of women aged 18-30 years with endometriosis using the certified questionnaire the Endometriosis Health Profile-30 (EHP-30). The Czech version of the EHP-30 was used in the study. A total of 184 women completed the questionnaire. Mean age of the women was 26.6 years (± 2.8 years).</p><p><strong>Materials and methods: </strong>Data were collected from 10 February 2023 to 8 October 2023 using the online platform Click4survey.</p><p><strong>Results: </strong>Summary index of the EHP-30 group was 57.0 points (± 20.43 points). The domain of powerlessness to control the disease had the greatest impact on women's quality of life at 66.4 points, followed by Social support at 58.4 points, then Emotional well-being at 58.2 points. With Pain at 51.3 points, and Self-image at 50.7 points as the final domain. Results showed that perception of pain did not increase with increasing age, and on the contrary, women in the youngest age group of 18-20 years perceived pain as the worst. The age of women did not statistically significantly affect the final index of the questionnaire or its individual dimensions.</p><p><strong>Conclusion: </strong>Based on the analysis and results obtained, we have obtained data on the domains of endometriosis, which can significantly contribute to a more effective understanding of the possibility of improving the quality of life of women aged 18-30 years with endometriosis and the procedures for their treatment.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 5","pages":"380-384"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not every seizure is eclampsia - a rare case of a brain abscess in a pregnant woman caused by Streptococcus pneumoniae from a dental source.","authors":"Dania M Moamar, Mus'ab Theeb Mustafa, Reema Ismaeel, Farah Alshamasneh, Nedal S Abusidreh, Osama M Jamous, Naser Aldain A Abu Lehyah","doi":"10.48095/cccg2025474","DOIUrl":"10.48095/cccg2025474","url":null,"abstract":"<p><p>We present a rare case of a brain abscess in a pregnant woman due to an untreated dental abscess, initially presenting as a new-onset seizure. This article highlights the need for a broad differential diagnosis for seizures in pregnancy, extending beyond the common assumption of eclampsia, and further emphasizing the importance of thorough history-taking and physical examination. We suggest integrating routine dental care into prenatal healthcare to reduce the risk of such serious events. Informed consent was obtained, and all identifiable information has been de-identified to protect patient confidentiality.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 6","pages":"474-478"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV infection and adverse perinatal outcomes - a meta-analysis of premature births, low birth weights, and small for gestational age newborns.","authors":"K Hurt, J Rakovic, J Matěcha, M Mojhova, F Zahálka, M Zikán","doi":"10.48095/cccg2025269","DOIUrl":"10.48095/cccg2025269","url":null,"abstract":"<p><p>HIV remains a significant global public health challenge, affecting millions of individuals with a disproportionate burden in sub-Saharan Africa. Despite advancements in antiretroviral therapy (ART) and global efforts to control transmission, the impact of HIV on pregnancy outcomes remains a topic of concern.</p><p><strong>Aim: </strong>This study aims to evaluate the association between maternal HIV infection and adverse pregnancy outcomes, specifically preterm birth (PTB), low birth weight (LBW), and small for gestational age (SGA) infants through a comprehensive meta-analysis.</p><p><strong>Materials and methods: </strong>A systematic search of English-language databases, including Medline, Web of Science, Ovid, Scopus, and Google Scholar, was conducted to identify relevant studies published between 2014 and 2024. Eligible studies included retrospective and prospective cohort studies with well-defined control groups of HIV-negative mothers. Studies that lacked appropriate control groups, included multiple pregnancies, or did not report adjusted statistical outcomes were excluded. A total of eight studies met the inclusion criteria for PTB analysis, five studies for LBW analysis, and five studies were selected for SGA analysis.</p><p><strong>Results: </strong>Meta-analysis using a random-effects model demonstrated a statistically significant association between maternal HIV infection and PTB (OR = 1.55; 95% CI 1.38-1.74; p &lt; 0.001), LBW (OR = 1.57; 95% CI 1.24-1.98; p &lt; 0.001), and an increased risk of SGA (OR = 1.24; 95% CI 1.10-1.40; p &lt; 0.001). Heterogeneity was moderate for PTB (I² = 38.2%) and LBW (I² = 55.9%) while it was low for SGA (I² = 7.6%), indicating consistency across studies. Egger's test showed minimal publication bias.</p><p><strong>Discussion: </strong>These findings highlight the adverse effects of HIV on pregnancy outcomes, emphasizing the need for continued monitoring and optimization of ART regimens to mitigate risks. Further research is warranted to explore the influence of different ART combinations and immune system dynamics on fetal development.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 4","pages":"269-277"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Status of a lipid accumulation product, triglycerides/ glucose index and visceral adiposity index on cardiometabolic risk factors in young polycystic ovary syndrome patients.","authors":"Gaye Arslan, Gökçenur Karakelleoğlu, Cihan Karadağ","doi":"10.48095/cccg2025457","DOIUrl":"10.48095/cccg2025457","url":null,"abstract":"<p><strong>Objective: </strong>To determine whether the triglycerides/glucose index (TyG-index), lipid accumulation product (LAP), and visceral adiposity index (VAI) would differ in young polycystic ovary syndrome (PCOS) patients when compared to the non-PCOS group, and to investigate the relationship between these markers and cardiovascular disease (CVD) risk in PCOS patients.</p><p><strong>Materials and methods: </strong>One hundred and ninety two women with PCOS, and 148 age and body mass index (BMI) matched healthy women without PCOS were enrolled. Levels of serum androgens, sex hormones, lipids, fasting glucose, fasting insulin, and N-terminal pro-brain natriuretic peptide (Nt-probnp) were determined. The 75 g oral glucose tolerance test was performed. The Homeostatic Model Assessment-Insulin Resistance Index (HOMA-IR) and Matsuda insulin sensitivity index were calculated. Levels of TyG-index, LAP, and VAI were determined.</p><p><strong>Results: </strong>TyG, LAP, and VAI were significantly higher in PCOS patients than in the control group (P = 0.001 vs. P = 0.001 vs. P = 0.001, resp.). HOMA-IR was significantly higher in PCOS patients and Matsuda ISI was significantly lower in PCOS patients (P = 0.001 vs. P = 0.001, resp.). Levels of Nt-probnp were significantly higher in PCOS patients (P = 0.001). Serum total testosterone and androstenedione levels had significant correlations with TyG, LAP, and VAI. Nt-probnp was significantly correlated with TyG, LAP, and VAI. LDL was positively correlated and HDL was negatively correlated with TyG-index, LAP, and VAI.</p><p><strong>Conclusion: </strong>PCOS patients have increased values of TyG-index, LAP, and VAI. TyG index, LAP, and VAI may indicate an increased risk of CVD and hyperandrogenism in PCOS patients.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 6","pages":"457-462"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal total atrioventricular block in transgender man with systemic lupus erythematosus -  literature review and establishment of a protocol with management and treatment with terbutaline.","authors":"Maria Elisa Martini Albrecht, Nicole Rodrigues da Cunha Resende de Miranda, Milena Giuberti, Edward Araujo Júnior","doi":"10.48095/cccg202552","DOIUrl":"10.48095/cccg202552","url":null,"abstract":"<p><p>This case report describes a case of total atrioventricular block (TAVB) with positive anti-Ro/SSA antibodies in a transgender man who began follow-up at 31 weeks and 3 days of gestation. Despite many disagreements regarding treatment, corticosteroids were recommended for this patient. The fetal ventricular rate at the second weekly visit was 50 bpm and terbulin was started to increase heart rate. Hospitalization and intravenous terbutaline for 3 days was chosen to better control maternal symptoms and monitor fetal vital signs, as well as daily monitoring of the ventricular rate. There was an increase in baseline ventricular rate of approximately 15%. After discharge from the hospital, weekly control fetal echocardiography was performed in addition to the indices proposed by Huhta for echocardiographic assessment of fetal cardiac function. Fetal ventricular rate in ambulatory controls did not fall below 55 bpm. Cesarean section was indicated at 35 weeks and 4 days of gestation due to premature rupture of ovular membranes. A male newborn was delivered weighing 2,250 grams with Apgar scores of 8 and 9 at the 1st and 5th minute, respectively. After 88 days of life, the infant was weighing 4,580 grams and a definitive bicameral epicardial pacemaker was implanted without complications. Even if there is a transient increase in fetal ventricular rate with the use of terbutaline, a pacemaker is indicated. Delivery should be at term to allow the fetus to achieve adequate weight and pulmonary maturity for definitive pacemaker implantation.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 1","pages":"52-57"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of kisspeptin, neurokinin, and dynorphin neurons on regulation of reproduction.","authors":"Jana Racková","doi":"10.48095/cccg2025413","DOIUrl":"https://doi.org/10.48095/cccg2025413","url":null,"abstract":"<p><p>Gonadotropin-releasing hormone pulsatility is under the influence of hypothalamic neuropeptides, especially neurons expressing kisspeptin, neurokinin B, and dynorphin. These hypothalamic cells are called KNDy neurons. By integrating hormonal and environmental stimuli in the brain, they modulate the effects on neuropeptide release and control the frequency and amplitude of pulses. The relationship between KNDy neurons and gonadal hormones is essential for the initiation of puberty, regulation of the menstrual cycle, and reproduction. Steroid hormones have a feedback effect on the modulation of the activity of KNDy neurons, as their membrane and cell nucleus express receptors for estradiol, progesterone, and testosterone. Recent research suggests a close relationship with the pathophysiology of infertility, pathological pregnancy, menstrual cycle disorders, polycystic ovary syndrome, endometriosis, and vasomotor symptoms in perimenopause.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"90 5","pages":"413-417"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}