Dita Münzová, Petra Bretová, Martin Pešl, Vít Weinberger, Luboš Minář, Michal Felsinger
{"title":"Risk of atrial fibrillation in endometrial cancer patients.","authors":"Dita Münzová, Petra Bretová, Martin Pešl, Vít Weinberger, Luboš Minář, Michal Felsinger","doi":"10.48095/cccg2024439","DOIUrl":"https://doi.org/10.48095/cccg2024439","url":null,"abstract":"<p><strong>Objective: </strong>The study aimed to define atrial fibrillation frequency in endometrial cancer patients, identify risk factors, and propose preventive steps for early detection and treatment leading to decreasing cardiovascular risk. Secondly, we aimed to highlight this topic by presenting a systematic literature review.</p><p><strong>Methodology: </strong>Retrospective analysis of endometrial cancer patients treated at the Department of Gynecology and Obstetrics at University Hospital Brno between 2006 and 2023 complemented by a systematic literature review.</p><p><strong>Results: </strong>The incidence of atrial fibrillation in endometrial cancer patients in our study group (1,101 patients) was 10.4%. Overall, 27% of patients suffered from obesity, hypertension, and diabetes, 26% from both hypertension and obesity, and 10% from diabetes and obesity. The incidence of other risk factors and their combination was less than 10%.</p><p><strong>Conclusion: </strong>Endometrial cancer patients are at a higher risk of developing atrial fibrillation compared with the general population. The risk is enhanced by the presence of other common risk factors such as hypertension, diabetes, and obesity.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 6","pages":"439-444"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pandemic fear and psychological resilience in pregnant women after the pandemic - a study in Turkey.","authors":"Merve Akkuş, Fatih Akkuş","doi":"10.48095/cccg202422","DOIUrl":"10.48095/cccg202422","url":null,"abstract":"<p><strong>Aims: </strong>The aim of this study was to investigate the levels of pandemic-related fear, depression, stress and anxiety in pregnant women in different trimesters after the pandemic and to examine their relationship with psychological resilience. Methods: A total of 250 women were included in the study, including 125 pregnant women and 125 healthy controls. The participants were divided into three groups according to their trimester of pregnancy. The Depression-Anxiety-Stress Scale 21 (DASS-21), the Epidemic Disease Anxiety Scale (EDAS) and the Short Psychological Resilience Scale (SPRS) were used to measure depression, anxiety, stress and psychological resilience. Results: Pregnant women had significantly higher DASS-21 total scores [19 (4-42) ] than healthy controls [11 (1-42) ], P = 0.001. The prevalence of depression, anxiety and stress was 23.2%, 44% and 20% respectively in pregnant women compared to 12.8%, 31.2% and 9.6% in healthy controls. DASS-21 total scores were highest in the 1st (21.2 ± 5.8) and 3rd (22.8 ± 8.9) trimesters and lowest in the 2nd (16.1 ± 6.9) trimesters. The DASS-21 total score was positively correlated with the EDAS total score and the pandemic perception subscale. SPRS total score was negatively correlated with anxiety, stress and DASS-21 total score. Conclusion: Pregnant women experienced higher levels of depression, anxiety, stress, and pandemic anxiety than non-pregnant women in the post-pandemic period. Psychological resilience was negatively associated with depression, anxiety, and stress in pregnant women. These findings indicate that the pandemic negatively affects the mental health of pregnant women and the importance of providing psychological support services to protect their mental health.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 1","pages":"22-28"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139991451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosekeila Simões Nomelini, Priscylla Kelliny Aparecida Antão, Millena Prata Jammal, Cid Almeida De Lima, Paula Carolina Arvelos Crispim, Agrimaldo Martins-Filho, Renata Margarida Etchebehere, Eddie Fernando Candido Murta
{"title":"Evaluation of cytokine immunostaining in ovarian neoplasms and endometriomas.","authors":"Rosekeila Simões Nomelini, Priscylla Kelliny Aparecida Antão, Millena Prata Jammal, Cid Almeida De Lima, Paula Carolina Arvelos Crispim, Agrimaldo Martins-Filho, Renata Margarida Etchebehere, Eddie Fernando Candido Murta","doi":"10.48095/cccg2024377","DOIUrl":"10.48095/cccg2024377","url":null,"abstract":"<p><strong>Objective: </strong>The objective of our study was to quantify and compare the immunostaining of IL-2, IL-5, IL-6, IL-8, and TNF-α in endometriomal tissue, non-neoplastic tumors, benign neoplasms, and malignant ovarian neoplasms.</p><p><strong>Materials and methods: </strong>The study involved 90 patients: 15 non-neoplastic ovarian lesions, 28 ovarian benign neoplasms, 28 ovarian malignant neoplasms, and 19 ovarian endometriomas were diagnosed. Immunohistochemistry was performed for cytokines IL-2, IL-5, IL-6, IL-8, and TNF-α and their concentrations were compared in these groups. Fisher's exact test was used, requiring a P-value of < 0.05 for significance.</p><p><strong>Results: </strong>IL-5 and IL-8 epithelial immunostaining is stronger in endometriomas than in ovarian cancer (P-values of 0.0046 and 0.0149, resp.). The stromal immunostaining of TNF-α, IL-5, IL-6, and IL8 is stronger in endometriomas than in ovarian cancer (P-values of 0.0008, < 0.0001, 0.0003, and 0.0006, resp.).</p><p><strong>Conclusions: </strong>Stronger immunostaining of some cytokines in endometriomas compared to ovarian cancer reflects an inflammatory and immune response that could be future targets for new discoveries about the infiltrative behavior of endometriosis.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 5","pages":"377-384"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Jouzová, Lukáš Hruban, Jakub Turek, Martin Jouza, Romana Gerychová, Tereza Tureková, Petr Janků
{"title":"Prenatal diagnosis in estimating the prognosis of sacrococcygeal teratoma.","authors":"Anna Jouzová, Lukáš Hruban, Jakub Turek, Martin Jouza, Romana Gerychová, Tereza Tureková, Petr Janků","doi":"10.48095/cccg2024219","DOIUrl":"https://doi.org/10.48095/cccg2024219","url":null,"abstract":"<p><p>: Sacrococcygeal teratoma is a rare congenital malformation, the prognosis depends on factors affecting foetal development. The diagnosis is based on ultrasound examination, especially the evaluation of the detailed morphology of the foetus in the 20th week of pregnancy. Therefore, it is crucial to keep looking for ultrasound markers that would prenatally determine the most accurate prognosis for the foetus. Now, we rely on a small number of studies with a predominance of case reports. We offer a literature review of the essential information concerning sacrococcygeal teratoma diagnostics, therapy, and complications of sacrococcygeal teratomas in connection with prenatal diagnosis. It turns out that in cases with a favourable prognosis according to prenatal ultrasound examination and adequate surgical treatment after childbirth, the prognosis of this congenital malformation is excellent.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 3","pages":"219-223"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Brandejsová, Hynek Heřman, Petra Hanulíková, Lubomír Hašlík, Alexandra Regendová, Ladislav Krofta, L Feyereisel
{"title":"Hydrops of a fetus of unknown etiology with the development of severe intracranial hemorrhage.","authors":"Anna Brandejsová, Hynek Heřman, Petra Hanulíková, Lubomír Hašlík, Alexandra Regendová, Ladislav Krofta, L Feyereisel","doi":"10.48095/cccg2024479","DOIUrl":"https://doi.org/10.48095/cccg2024479","url":null,"abstract":"<p><p>Prenatally diagnosed intracranial hemorrhage in the fetus is associated with a wide range of neonatal disorders, from completely uncomplicated physiological development to severe neurological impairment or death. The incidence is 0.6-1/1,000 births. Intracranial hemorrhage, depending on the anatomical location, is classified as intraventricular, intracerebral, cerebral, subarachnoid, and subdural. In this case report, we describe a rare case of spontaneous intracranial hemorrhage in a fetus monitored for hydrops and pregnancy complicated by polyhydramnios. A literature research was carried out. In the discussion, we present the diagnostic algorithm and the results of the examinations performed. To complete the case report, we add information about the management of childbirth and early death of the newborn.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 6","pages":"479-481"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiří Špaček, Petr Hoffmann, Miroslav Lojík, Igor Guňka, Miloš Broďák, Jiří Petera, Jiří Špaček
{"title":"Ureteroarterial fistula - a severe manifestation of urological toxicity with possibly fatal consequences.","authors":"Jiří Špaček, Petr Hoffmann, Miroslav Lojík, Igor Guňka, Miloš Broďák, Jiří Petera, Jiří Špaček","doi":"10.48095/cccg2024293","DOIUrl":"10.48095/cccg2024293","url":null,"abstract":"<p><strong>Aim: </strong>A retrospective audit from a urological center focused on urological fistulas that directly connect with the treatment of gynecological malignancy. Ureteroarterial fistulas, i.e., pathological communication between the ureter and the artery, are discussed in more detail.</p><p><strong>Materials and methods: </strong>Over a period of ten years, from 2011 to 2020, a group of 47 patients with a diagnosis of urinary fistula was retrospectively evaluated. These patients, with a history of treatment for gynecological malignancy, were sent to our clinic from local and non-regional departments in the Czech Republic. We found three cases of ureteroarterial fistula in the presented analysis that focused on urological toxicity of oncogynecological treatment.</p><p><strong>Results: </strong>Within the mentioned period of ten years, we recorded 64 cases of urinary fistulas, and 47 patients (73.4%) were directly related to oncogynecological treatment. In the group with gynecological tumors, we found three patients (6.4%) with a diagnosis of ureteroarterial fistula, two of whom died directly related to this complication (exsanguination). These patients were treated for cervical cancer. All of them underwent radiotherapy during the treatment.</p><p><strong>Conclusion: </strong>Ureteroarterial fistulas are the most severe complications that can occur in medicine. This work confirms that we have encountered these cases even recently. Management is highly demanding for patients affected in this way and requires multidisciplinary cooperation. Endovascular intervention methods can control bleeding in emergency situations with non-surgical approaches. However, they are usually the first step towards a definitive surgical solution.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 4","pages":"293-297"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fecal incontinence risk factors and pregnancy.","authors":"Serhii Vasyliuk, Andrii Cheredarchuk, Mariana Rymarchuk, Rostislav Bondarev, Olha Proshchenko, Artem Mykytyuk","doi":"10.48095/cccg2024102","DOIUrl":"10.48095/cccg2024102","url":null,"abstract":"<p><strong>Materials and methods: </strong>We conducted an analysis on 231 pregnant women. A proctologist examined the patients three times: in the 1st trimester (within the first 15 weeks), in the 3rd trimester (29-40 weeks), and 12 months after childbirth.</p><p><strong>Results: </strong>The total number of fecal incontinence observations among women included in the study was 66 cases (28.6%), detected at the final visit. Risk factors for fecal incontinence with a high probability were age over 36 years (P = 0.001), low physical activity (P = 0.034), three or more pregnancies resulting in childbirth (P = 0.022), history of hemorrhoids (P = 0.027), perianal discomfort on the first visit (P = 0.045), and constipation on the first visit (P = 0.006). Factors such as being overweight, marital status, education, living conditions, living area, and infant size did not have significance for fecal incontinence.</p><p><strong>Discussion: </strong>Pregnancy- and obstetric-related risk factors contributing to fecal incontinence are multifactorial, including factors such as multiple childbirths with trauma to the pelvic muscles or anal sphincter muscles, chronic constipation, age, and vaginal deliveries. However, currently, there is no clear concept for the prevention of fecal incontinence in pregnant women.</p><p><strong>Conclusion: </strong>The prevalence of fecal incontinence among pregnant women is 12.9%, which increases to 28.6% one year after childbirth. The most common complaint was involuntary passage of intestinal gas. Risk factors for fecal incontinence with a high probability included being over 36-years old, low physical activity, three or more pregnancies resulting in childbirth, a history of hemorrhoids, perianal discomfort, and constipation in the 1st trimester of pregnancy.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 2","pages":"102-106"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Female orgasm, reproduction and couple relationships.","authors":"Zlatko Pastor","doi":"10.48095/cccg202452","DOIUrl":"10.48095/cccg202452","url":null,"abstract":"<p><p>A deficit or problematic achievement of female orgasm is often classified as a sexual disorder that creates complications in the sex life of couples. This assumption is generally accepted, even though vaginal anorgasmia is an accepted statistical norm and non-coital methods of generating female orgasm are not as easy as they are for men. Female orgasms manifest themselves in different ways; they are variable and can be dependent on a number of variable factors. Some theories suggest a high degree of correlation between the capacity for orgasmic experience, sexual attitudes and behaviour, but also with reproductive potential or the stability of the given couple's relationship. Female orgasm is often seen as a discriminatory mechanism influencing attitudes towards sexuality or even as a kind of fertility catalyst. There is no consensus on the importance of female orgasm. The results of some relevant studies refute theories about the female orgasm's positive influence on adaptive functions of the couple's relationship, as well as its influence on fertility. The orgasm in women is most likely an evolutionary by-product of its male variant, since the clitoris and penis have an identical embryonic basis of development. Female anorgasmia should not be considered an unquestioned diagnosis, let alone a psychiatric construct leading to a paradigm in which anorgasmia is categorically the cause of frustration or other problems.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 1","pages":"52-55"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139991407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paolo Meloni, Terenzia Simari, Lai Roberta, Ilaria Cassella, Rodolfo Brizio, Roberto Conturso, Davide Russo, Edward Araujo Júnior, Gabriele Tonni
{"title":"Occult invasive cervical cancer, FIGO stage III, with a negative Pap smear test - clinical presentation and brief review of the literature.","authors":"Paolo Meloni, Terenzia Simari, Lai Roberta, Ilaria Cassella, Rodolfo Brizio, Roberto Conturso, Davide Russo, Edward Araujo Júnior, Gabriele Tonni","doi":"10.48095/cccg202434","DOIUrl":"10.48095/cccg202434","url":null,"abstract":"<p><p>Occult cervical cancer is rare and is diagnosed incidentally after a simple hysterectomy. The staging upon histological examination is usually International Federation of Gynecology and Obstetrics (FIGO) stage I, rarely higher with negative preoperative diagnostic tests such as a Pap smear. The clinical case in question is a rare case of cervical carcinoma diagnosed at the time of hysterectomy with a negative exo-endocervical Pap smear, diagnostic tests including transvaginal ultrasound, abdominal magnetic resonance imaging and abdominal computed tomography with a diagnosis of degenerating myoma or suspected sarcoma. In the operating theatre, the surgical radicality was modified and the operation was completed with removal of the parameters, vaginal collar and bilateral pelvic lymphadenectomy. The final histological examination indicated FIGO stage III, for which the patient underwent radiotherapy and chemotherapy.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 1","pages":"34-39"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139991449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usage of the levonorgestrel releasing intrauterine system in perimenopause.","authors":"Tomáš Fait","doi":"10.48095/cccg2024156","DOIUrl":"10.48095/cccg2024156","url":null,"abstract":"<p><p>Levonorgestrel releasing intrauterine system have excellent contraceptive efficacy with simultaneous lowering of menstruation's blood loss. It could be used for therapy of endometrial hyperplasia in perimenopause. In position of gestagen part of the hormone replacement therapy it has high control of endometrial proliferation. It is conjoined with the zero increasing of risk of thromboembolic disease in combination with transdermal oestrogen's application.</p>","PeriodicalId":43333,"journal":{"name":"Ceska Gynekologie-Czech Gynaecology","volume":"89 2","pages":"156-159"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141559963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}