Chronic Wound Care Management and Research最新文献_第8页

Wound pruritus: pathophysiology and management 创面瘙痒:病理生理及处理

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-08-12 DOI: 10.2147/CWCMR.S70360

J. Paul

引用次数: 4

Wound care matrices for chronic leg ulcers: role in therapy 慢性腿部溃疡的伤口护理基质:在治疗中的作用

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-07-24 DOI: 10.2147/CWCMR.S54680

Hitomi Sano, S. Kouraba, R. Ogawa

{"title":"Wound care matrices for chronic leg ulcers: role in therapy","authors":"Hitomi Sano, S. Kouraba, R. Ogawa","doi":"10.2147/CWCMR.S54680","DOIUrl":"https://doi.org/10.2147/CWCMR.S54680","url":null,"abstract":"Chronic leg ulcers are a significant health care concern. Although deep wounds are usually treated by flap transfers, the operation is invasive and associates with serious complications. Skin grafts may be a less invasive means of covering wounds. However, skin grafts cannot survive on deep defects unless high-quality granulation tissue can first be gen - erated in the defects. Technologies that generate high-quality granulation tissue are needed. One possibility is to use wound care matrices, which are bioengineered skin and soft tissue substitutes. Because they all support the healing process by providing a premade extracellular matrix material, these matrices can be termed \"extracellular matrix replacement therapies\". The matrix promotes wound healing by acting as a scaffold for regeneration, attracting host cytokines to the wound, stimulating wound epithelialization and angiogenesis, and providing the wound bed with bioactive components. This therapy has lasting benefits as it not only helps large skin defects to be closed with thin skin grafts or patch grafts but also restores cosmetic appearance and proper function. In particular, since it acts as a layer that slides over the subcutaneous fascia, it provides skin elasticity, tear resistance, and texture. Several therapies and products employing wound care matrices for wound management have been developed recently. Some of these can be applied in combination with negative pressure wound therapy or beneficial materials that promote wound healing and can be incorporated into the matrix. To date, the clinical studies on these approaches suggest that wound care matrices promote spontaneous wound healing or can be used to facilitate skin grafting, thereby avoiding the need to use invasive surgical tissue transfer strategies.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"2 1","pages":"113-118"},"PeriodicalIF":2.1,"publicationDate":"2015-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/CWCMR.S54680","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68335764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical efficacy of dressings for treatment of heavily exuding chronic wounds 敷料治疗慢性重度渗液创面的临床疗效

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-06-10 DOI: 10.2147/CWCMR.S60315

C. Wiegand, J. Tittelbach, U. Hipler, P. Elsner

{"title":"Clinical efficacy of dressings for treatment of heavily exuding chronic wounds","authors":"C. Wiegand, J. Tittelbach, U. Hipler, P. Elsner","doi":"10.2147/CWCMR.S60315","DOIUrl":"https://doi.org/10.2147/CWCMR.S60315","url":null,"abstract":"The treatment of chronic ulcers is a complex issue and presents an increasing problem for caregivers everywhere. This is especially true in Germany, where more than 4 million chronic wounds are treated each year. Therapeutic decisions must be patient-centered and reflect wound etiology, localization, and healing status. The practice of using the same wound dressing during the entire healing period is no longer reasonable. Instead, multiple types of dressings may be needed for a single wound over its healing trajectory. Selection of the most appropriate dress- ing should be based on wound phase, depth, signs of infection, and level of exudate. Moisture balance is critical in wound care; dryness will hamper epithelial cell migration while excessive generation of fluid causes maceration at the wound margins. Hence, exudate management is a key issue in chronic wound therapy, particularly given that exudate from chronic wounds has a composition different from that of acute wound fluid. Several studies have shown that exudates from non-healing wounds contain significantly elevated levels of protease activity, increased formation of free radicals, and abundant amounts of proinflammatory cytokines, while concentra - tions of growth factors and protease inhibitors are markedly decreased. Application of dressings that remove and sequester excess amounts of wound fluid may not only help in restoring the correct balance of moisture, but also support the wound healing process by preventing tissue deterioration caused by abundant protease activity. Several types of dressings, such as hydrogels, hydrocolloids, alginates, hydrofibers, foams, and superabsorbent dressings, are reviewed here","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"61 1","pages":"101-111"},"PeriodicalIF":2.1,"publicationDate":"2015-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/CWCMR.S60315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68335949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Chronic venous leg ulcers – role of topical zinc 慢性静脉性腿部溃疡-局部锌的作用

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-06-03 DOI: 10.2147/CWCMR.S80750

Sara F. Maher

{"title":"Chronic venous leg ulcers – role of topical zinc","authors":"Sara F. Maher","doi":"10.2147/CWCMR.S80750","DOIUrl":"https://doi.org/10.2147/CWCMR.S80750","url":null,"abstract":": Topical zinc has been used in the treatment of wounds for over 3,000 years, and is reported to have antiseptic, astringent, anti-inflammatory, antimicrobial, and wound healing properties. Fourteen studies were identified and reviewed, to assess the efficacy of this treatment modality as either a bandage or skin protectant in the treatment of venous ulcers. The authors of three studies reported improved healing time or success rate in wounds treated with zinc-based products. However, the authors of one study attributed the faster healing rate mainly to the extra compression (that improved venous blood return), delivered by the non-elastic paste bandage, and not by the zinc oxide alone. The quality of evidence is fair, as 50% of the studies were conducted prior to 2000 and 50% of the studies utilized fewer than 45 patients randomized to two or more groups. Other treatments have been reported to be more cost-effective than zinc, including hydrocolloids, four-layer compression systems, and CircAid Thera-boots. Finally, zinc was reported to be less comfortable, less easy to use, and caused increased pain, in comparison to other products on the market. This literature review, therefore, demonstrated that current evidence is insufficient to determine the effectiveness of zinc-based products in the treatment of venous wounds. Future research is needed focusing on larger, high-quality trials with an emphasis on quality of life issues and cost-effectiveness of treatment.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"2 1","pages":"95-100"},"PeriodicalIF":2.1,"publicationDate":"2015-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/CWCMR.S80750","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68337241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Safety and efficacy of hyperbaric oxygen therapy in chronic wound management: current evidence 高压氧治疗在慢性伤口治疗中的安全性和有效性:目前的证据

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-04-22 DOI: 10.2147/CWCMR.S60319

P. Eggleton, A. Bishop, G. Smerdon

引用次数: 16

Negative pressure wound therapy: clinical utility 负压创伤治疗的临床应用

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-04-07 DOI: 10.2147/CWCMR.S48885

H. Sandoz

引用次数: 8

Economic benefit of a polyacrylate-based hydrogel compared to an amorphous hydrogel in wound bed preparation of venous leg ulcers 聚丙烯酸酯基水凝胶与无定形水凝胶在腿部静脉溃疡伤口床制备中的经济效益比较

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-04-07 DOI: 10.2147/CWCMR.S78580

D. Kaspar, Jörg Linder, P. Zöllner, U. Simon, H. Smola

引用次数: 1

Beneficial and deleterious bacterial–host interactions in chronic wound pathophysiology 慢性伤口病理生理学中有益和有害的细菌-宿主相互作用

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-04-02 DOI: 10.2147/CWCMR.S60317

C. Watters, Tony T. Yuan, K. Rumbaugh

引用次数: 22

Evaluation of an advanced pressure ulcer management protocol followed by trained wound, ostomy, and continence nurses: a non-randomized controlled trial 高级压疮管理方案的评估，随后训练伤口，造口和失禁护士:一项非随机对照试验

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-02-24 DOI: 10.2147/CWCMR.S73093

Toshiko Kaitani, G. Nakagami, J. Sugama, M. Tachi, Yutaka Matsuyama, Y. Miyachi, T. Nagase, Yukie Takemura, H. Sanada

引用次数: 2

Clinical utility of foam dressings in wound management: a review 泡沫敷料在伤口处理中的临床应用综述

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2015-02-17 DOI: 10.2147/CWCMR.S50832

J. Nielsen, K. Fogh

引用次数: 24