{"title":"A Moisture-Balancing Hydropolymer Gel Dressing with a Tissue Boost Effect - Experimental and Clinical Evidence","authors":"Cornelia Wiegand, Ulrike Wesenberg, Jan Heggemann","doi":"10.2147/cwcmr.s422493","DOIUrl":"https://doi.org/10.2147/cwcmr.s422493","url":null,"abstract":"Purpose: Chronic wounds are impaired in their healing processes and often require a tissue boost to restart healing progression. Dressings of all forms have been used extensively for decades and a variety of dressings was specifically designed for chronic wounds. A dressing based on a hydropolymer gel matrix with a semi-permeable polyurethane backing is thought to provide an optimal balanced wound moisture environment and could hence positively affect the biochemical composition of exudate. However, the mechanism behind the technology is described sparsely. Patients and Methods: We herein report in vitro data to support the mode of action of the hydropolymer gel dressing concerning fluid management, protease binding and thermal insulation. Moreover, a non-interventional prospective study examined the use of the unique hydropolymer gel dressing on pain levels. Results: Data demonstrated a possible tissue boost by retaining as well as providing fluid, depending on the exudate amount, and by binding proinflammatory proteases. The dressing was further able to stabilize growth factors and provide thermal insulation, thereby positively supporting keratinocyte proliferation and migration in vitro. Furthermore, a significant reduction of the pain level after application could be observed clinically. Conclusion: Together, these factors provide a beneficial environment for wound healing and restarting stagnating wounds (or providing optimal conditions for acute wounds). In addition, the dressing appeared to be a good choice for painful wounds.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134935928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kate Meredith, Alison Jones, Victoria Towers, Daniel Metcalf
{"title":"Ability of Different Non-Antimicrobial Wound Dressings to Remove Bacteria from Surfaces Using in vitro Planktonic and Mature Biofilm Models","authors":"Kate Meredith, Alison Jones, Victoria Towers, Daniel Metcalf","doi":"10.2147/cwcmr.s421986","DOIUrl":"https://doi.org/10.2147/cwcmr.s421986","url":null,"abstract":"","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"1 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46212124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic Wound Management: The Significance of Evidence and Technology","authors":"","doi":"10.1007/978-3-031-26110-7","DOIUrl":"https://doi.org/10.1007/978-3-031-26110-7","url":null,"abstract":"","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"68 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87837110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Ciprandi, Serena Crucianelli, Francesca Grussu, G. Spuntarelli, Simone Di Marino, U. Urbani, P. Bernaschi, A. Sisto, M. I. Rizzo, M. Zama
{"title":"Meeting the Challenges in Pediatric Wound Care: Our 15-Year Experience with Dialkylcarbamoyl Chloride-Coated Dressing Technology in Acute and Chronic Wounds","authors":"G. Ciprandi, Serena Crucianelli, Francesca Grussu, G. Spuntarelli, Simone Di Marino, U. Urbani, P. Bernaschi, A. Sisto, M. I. Rizzo, M. Zama","doi":"10.2147/cwcmr.s376889","DOIUrl":"https://doi.org/10.2147/cwcmr.s376889","url":null,"abstract":": Although similar in structure, pediatric skin is more delicate and vulnerable compared with adult skin and, as a result, is more prone to wounding. The immune response in pediatric skin is underdeveloped because of immature inflammatory cells and lower number of bone marrow progenitor cells. Therefore, pediatric patients, particularly newborns, have weak responses to microorganisms. The use of antimicrobial agents (eg, antibiotics, antimicrobial wound dressings, etc.) to aid in the prevention and/or treatment of wounds prone to or which are infected is one treatment option. Antimicrobial wound dressings using DACC technology physically bind bacteria and reduce the need for chemically active antimicrobial agents . This perspective is intended to highlight the benefit of DACC technology wound dressings for the prevention and treatment of pediatric wounds related to wound infection. We have found that DACC technology dressings are of benefit in the treatment of pediatric wounds and offer a significant resource for the treatment","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45407997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Magnitude and Associated Factors of Diabetic Foot Ulcer Among Patients with Chronic Diabetic Mellitus in Northeast Ethiopia, 2021","authors":"Bantalem Tilaye Atinafu, Fetene Nigussie Tarekegn, G. Mulu, Worku Misganaw Kebede, Yideg Abinew, Yalew Mossie","doi":"10.2147/cwcmr.s364288","DOIUrl":"https://doi.org/10.2147/cwcmr.s364288","url":null,"abstract":"Introduction: Diabetic disease and its complications are major public health problems that result in long-term hospitalization, amputation, and poor quality of life for patients. This study aimed to determine the magnitude and associated factors of diabetic foot ulcers among patients with chronic diabetic mellitus in northeast Ethiopia. Methods: An institutional-based cross-sectional study was conducted. The sample was selected using a systematic random sampling technique based on inclusion criteria. Data were collected using a self-administered pre-tested structured questionnaire. The collected data were entered into EpiData 3.1 and exported to SPSS 25 for statistical analysis. A binary logistic regression model was used to analyze the association between dependent and independent variables. All variables with P -value <0.25 were included in multivariable logistic regression. Adjusted odds ratio at 95% confidence intervals and considered significant with P -value <0.05 in final statistical significance was used to determine the level of association. Results: The overall 283 samples of diabetic cases in the follow-up were included. The magnitude of diabetic foot ulcer was 7.1% (95% CI=3.92, 47.2%). Duration greater than 5 years (AOR=2.28, 95% CI=3.04, 17.69), history of ulceration (AOR=7.24, 95%, CI=1.25, 11.78), peripheral neuropathy (AOR=5.77, 95% CI=1.33, 12.155), oral hypoglycemic (AOR=3.2, 95% CI=4.02, 4.36) and insulin (AOR=2.6, 95% CI=1.75, 4.36) were found to be the significant factors of diabetic foot ulcer. Conclusion: The magnitude of diabetic foot ulcer patients was 7.2% and associated with duration of diabetes mellitus, history of ulceration, peripheral neuropathy, and oral hypoglycemic medication. Therefore, attention is needed for prevention, early detection, and caring for foot ulcers.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"1 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43801074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and Practice of Wound Care and Associated Factors among Nurses Working in South Wollo Zone Government Hospitals, Ethiopia","authors":"Belachew Tegegne, Feruza Yimam, Zemen Mengesha Yalew, Mekuriaw Wuhib, Leul Mekonnen, Yibeltal Asmamaw Yitayew, Sewunet Ademe, D. Tsegaye, Yeshiambaw Eshetie, M. Chanie","doi":"10.2147/cwcmr.s366322","DOIUrl":"https://doi.org/10.2147/cwcmr.s366322","url":null,"abstract":"","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48901492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathological Scar and Its Associated Factors Among Survivor of Burn Victim Pediatrics Admitted to South Gondar Zone Public Hospitals, Amhara Regional State, Ethiopia, 2020 – A Multi-Center Cross-Sectional Study","authors":"Chalie Marew Tiruneh, Amare Belachew, Sileshi Mulatu, Tigabu Desie, Moges Wubneh Abate, Adane Birhanu Nigat, Nigusie Selomon Tibebu, Belete Gelaw Walle, Agimasie Tigabu, Amsalu Belete","doi":"10.2147/CWCMR.S322794","DOIUrl":"https://doi.org/10.2147/CWCMR.S322794","url":null,"abstract":"of are at risk of burn-related to escape from the object, a with the with a resultant injury and Methods: Institutional cross-sectional study was used to study 375 hospitalized burn injury survivor pediatrics from 2015 to 2019. A simple random sampling method was used to select participants. Data were exported from Epidata version 4.6 to SPSS version 25 for analysis. In multivariable analysis, significant of the variables were considered at p-value of ≤0.05. Results: In total, 353 were included in the study. Of 353 burn injury survivors, the prevalence of pathological scar was 125 (35.4%). In multivariable analysis, depth of burn injury, time since burn injury, a patient who have a referred to physiotherapy by the surgeon, and surgical procedure is done after burn were statistically significant with a complication of burn injury survivors. Conclusion and Recommendation: This study revealed that the burden of pathological scar among survivors of burn injury was unacceptably high, which needs intervention from the concerned bodies. Since this high burden of complication might result from the limitation of applying Interburn recommendation, the Amhara regional health bureau and the South Gondar health department shall work in collaboration with Interburn to provide essential burn care and advanced burn care training for health care providers. The timely intervention of those who have a second- and third-degree burn, promoting early presentation to hospital, providing appropriate physiotherapy, and proper care for those who have surgical intervention may help to decrease pathological scar for burn victim children.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"1 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47000912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effectiveness of Topical Aid Sliding Sheet Potentially Used for Pressure Injury Treatment","authors":"M. Kohta, Yoshinori Nakamura, Shunji Yunoki","doi":"10.2147/CWCMR.S284180","DOIUrl":"https://doi.org/10.2147/CWCMR.S284180","url":null,"abstract":"Purpose: This study evaluated the effect of a new secondary dressing used as a topical aid sliding sheet for friction and shear force reduction on the mechanical stresses generated on human skin, including interface friction and internal shear force and pressure, using a polyurethane gel-based skin model. A case study was conducted to propose on how to clinically use the topical aid sliding sheet for pressure injury treatment in a home-care setting. Methods: A polyurethane gel-based skin model mimicking the mechanical properties of human skin was prepared. In parallel measurement of interface friction and internal shear force and pressure was performed using an experimental model consisting of the skin model, primary wound dressing, topical aid sliding sheet, and three-axis tactile sensor. The skin model was covered with the following single or combined dressings: group A, silicone-faced absorbent dressing (control); group B, silicone-faced absorbent dressing plus film dressing; and group C, silicone-faced absorbent dressing plus topical aid sliding sheet. Clinically, a standard primary wound dressing was applied to a female patient (age, 101 years) with pressure injury on the sacral region, and the dressing was overwrapped with the topical aid sliding sheet. Results: The static and dynamic coefficients of friction were significantly lower in group C than in groups A and B ( p < 0.05). The detected shear force in the skin model was reduced to approximately 66% and 62% in group C versus groups A and B, respectively ( p < 0.05). Clinically, the patient’s ulcer underwent complete epithelialization without wound-related complications. Conclusion: The topical aid sliding sheet significantly reduced interface friction and internal shear forces in the present skin model. The case study’s result showed the topical aid sliding sheet had the potential to use for pressure injury treatment at a home care.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48163960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manal M. Khan, V. R. Cheruvu, D. Krishna, Reena Minz, Michael Laitonjam, Rishabh Joshi
{"title":"A Current Overview of Chronic Wounds Presenting to a Plastic Surgery Unit in Central India","authors":"Manal M. Khan, V. R. Cheruvu, D. Krishna, Reena Minz, Michael Laitonjam, Rishabh Joshi","doi":"10.2147/CWCMR.S267428","DOIUrl":"https://doi.org/10.2147/CWCMR.S267428","url":null,"abstract":"Purpose: To analyze the demographic, clinical, and microbiological profile of patients presenting to our unit with chronic wounds of various etiologies with an intent to give a current overview of chronic wounds. Patients and Methods: We performed a prospective observational study of patients presenting with chronic wounds from October 2018 to September 2019. The study was conducted at the Department of Burns and Plastic Surgery of a tertiary care institute in a non-metropolitan city in Central India. A total of 103 patients were included in the study. Data collected from the patients included demographic details, history, clinical features, and relevant laboratory reports. Wound swabs obtained by Levine’s technique were sent for culture and sensitivity studies. Treatment was instituted according to the clinical picture and modified if necessary. Progress was monitored until the wound healed, either by conservative management or by surgical intervention. Patients were followed up for six months thereafter. Results: Most of the patients presented with lower limb wounds (n=81, 78.64%). Swab specimens from 103 wounds were cultured. Among the isolates, gram-negative organisms were more common than gram-positive organisms. Staphylococcus aureus was the most common species isolated, followed by Pseudomonas aeruginosa . The frequency of infections caused by other gram-negative organisms like Klebsiella pneumoniae, Escherichia coli , and Proteus mirabilis was on the rise. There were significant differences in the patterns of antimicrobial resistance in our patients. Sharp debridements were required in almost all cases for wound preparation. Most of the patients (n=74, 71.84%) underwent surgical intervention for achieving wound closure. Split-thickness skin grafting (STSG) was the most common surgical intervention performed (n=45, 43.68% patients), followed by local and distant flaps. Conclusion: Our study gives a current overview of the causes, clinical presentation, prevalent microbial flora, and their antibiotic susceptibilities prevalent in chronic wounds presenting to our unit. Treatments administered are discussed with emphasis on the different reconstructions performed.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"1 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/CWCMR.S267428","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42436997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Behnammoghadam, Zhila Fereidouni, Mostafa Keshavarz Rad, Abdolhadi Jahanfar, H. Rafiei, N. Kalal
{"title":"Nursing Students’ Attitudes Toward the Medical Device-Related Pressure Ulcer in Iran","authors":"Mohammad Behnammoghadam, Zhila Fereidouni, Mostafa Keshavarz Rad, Abdolhadi Jahanfar, H. Rafiei, N. Kalal","doi":"10.2147/cwcmr.s264576","DOIUrl":"https://doi.org/10.2147/cwcmr.s264576","url":null,"abstract":"Objective: Attitudes toward medical device-related pressure ulcers can affect the performance of nursing students in this regard. To date, no studies have examined nursing students’ attitudes toward medical device-related pressure ulcers. Therefore, this study aimed to examine nursing students’ attitudes toward medical device-related pressure ulcers. Methods: The present study was conducted in 2020 in Iran. The sample size was 187 nursing students who were in one of 5, 6, 7, or 8 semesters. To examine the nursing students’ attitudes, a specific questionnaire was used. The questionnaire consists of 11 questions that assess the attitudes of nursing students toward medical device-related pressure in two dimensions of “prevention” and “care”. The final score of this questionnaire ranged from 11 to 55. A higher score indicates a more positive attitude toward medical device-related pressure. Results: A total of 187 nursing students participated in the study. Eighty-eight participants (41.7%) reported that they received training on medical device-related pressure ulcers. A total of 163 participants (88%) reported that their training was not sufficient for medical device-related pressure ulcers. Out of the total, 155 students stated that they need to hold a training workshop on medical device-related pressure ulcers. The mean overall score of nursing students’ attitudes toward medical device-related pressure ulcers was 42.1±5.2. The mean scores of prevention and care dimensions were 21.8 and 20.2, respectively. No significant relationship was found between the mean score of the overall attitude and the student’s demographic variables ( p <0.05). Conclusion: The results of the present study showed that nursing students, despite insuffi-cient education, exhibited a positive attitude toward the prevention and care of medical device-related pressure ulcers. However, further studies are needed in this regard with different settings.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44420785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}