Chronic Wound Care Management and Research最新文献_第3页

The utility of negative pressure wound therapy with instillation for wound bed preparation 负压伤口滴注治疗在创面准备中的应用

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2019-07-01 DOI: 10.2147/CWCMR.S198418

Luis Fernández

引用次数: 0

Rare chemical burns: first response, early hospitalization and first treatment: retrospective analysis from a single center 罕见化学烧伤：首次反应、早期住院和首次治疗：来自单个中心的回顾性分析

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2019-07-01 DOI: 10.2147/CWCMR.S213100

H. Akelma, Z. A. Karahan, Ebru Tarıkçı Kılıç

引用次数: 1

The safety of an autologous whole blood clot product applied to full thickness dermal wounds in a porcine model for up to 18 days 自体全血凝块产品应用于猪模型全厚真皮伤口长达18天的安全性

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2019-06-01 DOI: 10.2147/CWCMR.S189836

T. Serena, I. Kushnir, Alon Kushnir, R. Yaakov, K. Eckert

{"title":"The safety of an autologous whole blood clot product applied to full thickness dermal wounds in a porcine model for up to 18 days","authors":"T. Serena, I. Kushnir, Alon Kushnir, R. Yaakov, K. Eckert","doi":"10.2147/CWCMR.S189836","DOIUrl":"https://doi.org/10.2147/CWCMR.S189836","url":null,"abstract":"Introduction: Blood has become a major source for wound care products due to its primary role in wound healing. The blood clot provides a ﬁ brin scaffold that serves as a protective, provisional extracellular matrix. The clot dries out and becomes a protective scab, under which a moist wound environment can be maintained. In this study, the safety of an autologous whole blood clot product was evaluated in porcine models. Methods: A total of 24 full thickness dermal wounds were analyzed (6 wounds on each of the 4 porcine models). Eighteen wounds received the whole blood clot product and 6 were treated with saline soaked gauze for 18 days. Reapplications occurred on days 6 and 12. Histological evaluations were carried out to detect the presence of kaolin. Percentage area reduction and adverse events related to the whole blood clot product were assessed. Results: Microscopic evaluation revealed that the whole blood clot product was associated with partial to complete wound reepithelialization, whereas minimal reepithelialization was present with the control. The mean reepithelialization score for the control wounds was 1.0, or 2.3 times less than the mean score for the intervention group. By day 18, the mean reduction in wound area was 41% (SD: 3.8) for the control wounds versus 66% (SD: 6.4) for the wounds treated with the whole blood clot product ( P <0.0001).","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/CWCMR.S189836","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49484826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Assessment of acceptability and ease of use of gelling fiber dressings in the management of heavily exuding wounds 凝胶纤维敷料在严重渗出伤口治疗中的可接受性和易用性评估

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2019-05-29 DOI: 10.2147/CWCMR.S162687

G. Naik, K. Harding

引用次数: 6

Management of digital ulcers in systemic sclerosis 系统性硬化症患者手指溃疡的处理

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2019-05-23 DOI: 10.2147/CWCMR.S181326

S. Barsotti, M. Di Battista, V. Venturini, A. Della Rossa, M. Mosca

引用次数: 6

Hyperbaric oxygen therapy for the management of chronic wounds: patient selection and perspectives 高压氧治疗慢性创伤的患者选择与展望

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2019-05-01 DOI: 10.2147/CWCMR.S175721

E. Huang, Marvin Heyboer Iii, D. Savaser

引用次数: 10

The combination of high bacterial count and positive biofilm formation is associated with the inflammation of pressure ulcers 高细菌计数和阳性生物膜形成的结合与压疮的炎症有关

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2019-02-01 DOI: 10.2147/CWCMR.S187733

Mao Kunimitsu, G. Nakagami, A. Kitamura, Yuko Mugita, K. Akamata, S. Sasaki, Chieko Hayashi, Yukie Mori, H. Sanada

{"title":"The combination of high bacterial count and positive biofilm formation is associated with the inflammation of pressure ulcers","authors":"Mao Kunimitsu, G. Nakagami, A. Kitamura, Yuko Mugita, K. Akamata, S. Sasaki, Chieko Hayashi, Yukie Mori, H. Sanada","doi":"10.2147/CWCMR.S187733","DOIUrl":"https://doi.org/10.2147/CWCMR.S187733","url":null,"abstract":"Objective: Evaluating the bacterial bioburden of pressure ulcers through bacterial count and pathogenicity is important but is currently difficult to perform in the clinical setting. In order to address this problem, we proposed two methods: 1) measurement of bacterial count using a quantitative device and 2) detection of biofilm formation by wound blotting. The purpose of this study was to investigate the relationship between the bacterial bioburden, assessed by combining these two methods, and the presence of wound inflammation. Patients and methods: The participants of this cross-sectional study were patients aged > 20years with category II, III, IV, or unstageable pressure ulcers examined during a routine round in an interdisciplinary pressure ulcer team between July 2014 and April 2018. Relevant clinical information, including bacterial count, biofilm formation, and presence of inflammation, was collected from the pressure ulcer round record. The relationship between the bacterial bioburden and the presence of inflammation was analyzed using multilevel logistic regression analysis. Results: We included 273 samples obtained from 98 patients. High bacterial count was significantly associated with wound inflammation ( P = 0.009) and positive biofilm formation tended to be associated with wound inflammation ( P = 0.076). In terms of combining these parameters, high bacterial count and positive biofilm formation were significantly associated with wound inflammation (OR: 4.61, 95% CI: 1.37–15.46, P = 0.013). Conclusion: Assessment using both bacterial count and biofilm detection parameters may provide more accurate evaluation of the bacterial bioburden of the wound and contribute to appropriate wound care.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/CWCMR.S187733","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47499972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Sharp wound debridement: patient selection and perspectives 尖锐伤口清创术：患者选择与展望

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2018-10-01 DOI: 10.2147/CWCMR.S146747

C. Harris, P. Coutts, Rose Raizman, N. Grady

引用次数: 1

Observations made on three patients suffering from ulcers of the lower limbs treated with Blue Light 对三名用蓝光治疗的下肢溃疡患者的观察

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2018-10-01 DOI: 10.2147/cwcmr.s172060

G. Mosti, S. Gasperini

引用次数: 8

Epidermolysis bullosa: a case report 大疱性表皮松解症1例

IF 2.1

Chronic Wound Care Management and Research Pub Date : 2018-08-01 DOI: 10.2147/CWCMR.S162849

C. Fife, R. Yaakov, T. Serena

{"title":"Epidermolysis bullosa: a case report","authors":"C. Fife, R. Yaakov, T. Serena","doi":"10.2147/CWCMR.S162849","DOIUrl":"https://doi.org/10.2147/CWCMR.S162849","url":null,"abstract":": Epidermolysis bullosa (EB), often referred to as the butterfly disease, is a group of rare genetic conditions characterized by skin that is delicate and fragile as butterfly wings. The skin blisters in response to friction, minor injury, or trauma. In certain types of EB, other organs, such as the esophagus, can also be affected, and secondary complications may require multiple interventions. While there has been significant progress in classifying the disease – identifying genes and proteins involved – there have been few advances in the treatment of the disease. The care of the EB patient focuses on management of symptoms, protecting the skin, and preventing complications. In this case report, the use of a multivalent wound-healing ointment (Terrasil®) was evaluated in a 60-year-old patient with a history of junctional EB. A polymerase chain reaction-based culturing was utilized to quantitatively test for bacteria and fungi at baseline and follow-up visits. Pain assessment and wound area were also documented at each visit. Following the application of the wound care ointment, there was a reduction in wound surface area on central (96%) and distal mid-back (92%) by treatment visit three, and there was a 96% reduction on the left shoulder blade ulcer by treatment visit four. Moreover, there was a noticeable drop in the percentage of bacteria detected by polymerase chain reaction. The wound care ointment was also effective in eliminating the fungal species and reducing pain, itching, blistering, and cracking around the wound.","PeriodicalId":43306,"journal":{"name":"Chronic Wound Care Management and Research","volume":"1 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/CWCMR.S162849","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44579167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13