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FDA Approves First Dietary Supplement under New Drug Application with the Indication of Serious or Life-Threatening Illnesses FDA批准了首个针对严重或危及生命疾病的新药申请的膳食补充剂
Pharmacology & Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2022.1312038
Huu S. Tieu, M. Loeffler
{"title":"FDA Approves First Dietary Supplement under New Drug Application with the Indication of Serious or Life-Threatening Illnesses","authors":"Huu S. Tieu, M. Loeffler","doi":"10.4236/pp.2022.1312038","DOIUrl":"https://doi.org/10.4236/pp.2022.1312038","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology & Pharmacy","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123177390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Role of Polyethylene Glycol and Silica for Dissolution Enhancement of Cefuroxime Axetil: In-Vitro Performance Evaluation and Characterization 聚乙二醇和二氧化硅对增强头孢呋辛酯溶出的作用:体外性能评价和表征
Pharmacology & Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2023.145012
Mst. Boby Aktar Bithy, Milon Kumar Ghosh, Ashim Kumar, Md. Rafiqul Islam Khan, M. I. I. Wahed, R. Barman
{"title":"Role of Polyethylene Glycol and Silica for Dissolution Enhancement of Cefuroxime Axetil: <i>In-Vitro</i> Performance Evaluation and Characterization","authors":"Mst. Boby Aktar Bithy, Milon Kumar Ghosh, Ashim Kumar, Md. Rafiqul Islam Khan, M. I. I. Wahed, R. Barman","doi":"10.4236/pp.2023.145012","DOIUrl":"https://doi.org/10.4236/pp.2023.145012","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122886084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Effects of Crystallinity on Drug Release Behaviour in Itraconazole- or Miconazole-Loaded PLGA Microparticles Prepared Using a Co-Grinding Method 用共磨法制备的伊曲康唑或咪康唑负载PLGA微颗粒结晶度对药物释放行为的影响
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2023.149022
Kazuhiro Matsuura, Honami Kojima, Miyako Yoshida, Takahiro Uchida
{"title":"Evaluating the Effects of Crystallinity on Drug Release Behaviour in Itraconazole- or Miconazole-Loaded PLGA Microparticles Prepared Using a Co-Grinding Method","authors":"Kazuhiro Matsuura, Honami Kojima, Miyako Yoshida, Takahiro Uchida","doi":"10.4236/pp.2023.149022","DOIUrl":"https://doi.org/10.4236/pp.2023.149022","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129401869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identified Analytical Profile for Microelements, Trace Metals, Amino Acids and Screening of Anti-Diabetic Activity from Flower and Leaf Extracts of Moringa oleifera in Streptozotocin (STZ)-Induced Diabetic Rats 链脲佐菌素(STZ)诱导的糖尿病大鼠辣木花叶提取物微量元素、微量金属、氨基酸分析谱及抗糖尿病活性筛选
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2022.136012
Hemalatha Kamurthy, Sirajunisa Talath
{"title":"Identified Analytical Profile for Microelements, Trace Metals, Amino Acids and Screening of Anti-Diabetic Activity from Flower and Leaf Extracts of <i>Moringa oleifera</i> in Streptozotocin (STZ)-Induced Diabetic Rats","authors":"Hemalatha Kamurthy, Sirajunisa Talath","doi":"10.4236/pp.2022.136012","DOIUrl":"https://doi.org/10.4236/pp.2022.136012","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"15 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120950039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Promising Actions of Certain Medicinal Plants of Bangladesh against Diabetes and Oxidative Stress: A Review 孟加拉国某些药用植物抗糖尿病和氧化应激的研究进展
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2022.1310030
A. Sarkar, Sozoni Khatun, T. Enam, M. Jahan, A. Sarker, Nilay Saha, Md. Ariful Islam, Shantanu Saha Sani
{"title":"Promising Actions of Certain Medicinal Plants of Bangladesh against Diabetes and Oxidative Stress: A Review","authors":"A. Sarkar, Sozoni Khatun, T. Enam, M. Jahan, A. Sarker, Nilay Saha, Md. Ariful Islam, Shantanu Saha Sani","doi":"10.4236/pp.2022.1310030","DOIUrl":"https://doi.org/10.4236/pp.2022.1310030","url":null,"abstract":"Diabetes is a metabolic illness defined by hyperglycemia that affects 10% of the world’s population. Diabetic complications such as blindness, kidney failure, and heart failure can develop if left untreated and are made worse by oxidative stress. Oxidative stress contributes to the rise of diabetic complications, particularly type-2 diabetes. In the blood vessels of diabetic individuals, it causes endothelial dysfunction. Diabetes is one of the leading causes of death worldwide. Nowadays, it is alarming that the number of diabetic patients is increasing dramatically. There are plenty of anti-diabetic drugs available on the market, but they possess several adverse effects and do not completely cure diabetes. It has now become a financial burden on patients, their families, and society as well. Medicinal plants have gained popularity in developed and developing countries over the last two decades because of their vast natural sources and lack of harmful effects compared to modern allo-pathic medications. According to the World Health Organization, traditional medicines, which are mostly manufactured from plants, are still used by 80% of the population in developing countries for the management and curing of ti-diabetic and antioxidant capabilities so that the researchers can develop newer anti-diabetic medications with minimal side effects to treat metabolic dysfunction, diabetic complications, and oxidative stress more effectively.","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127024044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Centrum Multivitamin Content Analysis—Over the Counter—OTC Medicine on Facebook Centrum多种维生素含量分析-在Facebook上的非处方药
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2022.1311037
Euripedes Fernandes de Oliveira J.
{"title":"Centrum Multivitamin Content Analysis—Over the Counter—OTC Medicine on Facebook","authors":"Euripedes Fernandes de Oliveira J.","doi":"10.4236/pp.2022.1311037","DOIUrl":"https://doi.org/10.4236/pp.2022.1311037","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127884526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pramipexole in Treatment Resistant Depression: A Case Review 普拉克索治疗难治性抑郁症一例回顾
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2023.147016
N. Abdallah, J. Kahn
{"title":"Pramipexole in Treatment Resistant Depression: A Case Review","authors":"N. Abdallah, J. Kahn","doi":"10.4236/pp.2023.147016","DOIUrl":"https://doi.org/10.4236/pp.2023.147016","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129057967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contribution to the Valorization of Plants Used in the Management of Rheumatic Diseases in Burkina Faso 对布基纳法索用于风湿病管理的植物增值的贡献
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2022.133006
Aminata P. Nacoulma, Gontili Reine Elodie Karambiri, N. R. Meda, M. J. Bangou, Moussa Ouedraogo, D. Ouédraogo
{"title":"Contribution to the Valorization of Plants Used in the Management of Rheumatic Diseases in Burkina Faso","authors":"Aminata P. Nacoulma, Gontili Reine Elodie Karambiri, N. R. Meda, M. J. Bangou, Moussa Ouedraogo, D. Ouédraogo","doi":"10.4236/pp.2022.133006","DOIUrl":"https://doi.org/10.4236/pp.2022.133006","url":null,"abstract":"Joint pain is a real public health problem. According to recent studies, it is increasingly common in sub-Saharan Africa and represents a cause of greater loss of working days than accidents, heart disease and infections. The aim of this study was to study the pharmacochemical and therapeutic evidence of ten (10) plants used in the management of joint pain by traditional health practitioners in Ouagadougou. We conducted a meta-analysis of the data from December 2018 to September 2019. The anti-inflammatory activity of the ten (10) plants retained the maximum consensus internationally. Trichilia emetica Vahl (35.25%), Guiera senegalensis J.F.G.mel. (31%), Calotropis procera (Ait) Ait.F. (28.29%) and Crescientia cujete L. (25.12%) had more than 25% internationally reliability for their effects on joint pain. The structural analogy between conventional drugs and the molecules found in these plants has been confirmed. Additional studies should be carried out in order to improve and secure the use of these plants, which represent a prominent option in the therapeutic offer. identified in Trichilia emetica Vahl, Guiera senegalensis J.F.G.mel., Calotropis procera (Ait) Ait.F. These observations strengthen scientific basis for the use of Trichilia emetica Vahl, Guiera senegalensis J.F.G.mel., Calotropis procera (Ait) Ait.F. and Crescientia cujete L. in inflammatory joint pain treatment. The subsequent evaluation of therapeutic equivalences will allow the devel-opment of plant-based phytomedicines, standardized in therapeutic equivalent of modern treatments per gram of dry plant material. Evaluation of QSAR of plant compounds as indolic alkaloids and modified triterpenic compounds with potent anti-inflammatory properties could give models for drug design and dis-covery in the area of new therapies development.","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116234768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial Stewardship: Knowledge and Attitudes of Pharmacy Staff on Antibiotic Dispensing Patterns, Use and Resistance in Benin 抗菌药物管理:贝宁药房工作人员对抗生素调剂模式、使用和耐药性的知识和态度
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2023.146014
A. Allabi, Areine Gracidie Agbo, Bawa Boya, Steward Mudenda
{"title":"Antimicrobial Stewardship: Knowledge and Attitudes of Pharmacy Staff on Antibiotic Dispensing Patterns, Use and Resistance in Benin","authors":"A. Allabi, Areine Gracidie Agbo, Bawa Boya, Steward Mudenda","doi":"10.4236/pp.2023.146014","DOIUrl":"https://doi.org/10.4236/pp.2023.146014","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123346385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Synthesis, Photophysical Properties and DNA-Photocleavage Activity of Silicon Phthalocyanine Derivatives 酞菁硅衍生物的合成、光物理性质及dna -光裂解活性
Pharmacology &amp;amp; Pharmacy Pub Date : 1900-01-01 DOI: 10.4236/pp.2022.136014
Kunhui Sun, Yanli Ge, Jun Yang, Xuelei Hu
{"title":"Synthesis, Photophysical Properties and DNA-Photocleavage Activity of Silicon Phthalocyanine Derivatives","authors":"Kunhui Sun, Yanli Ge, Jun Yang, Xuelei Hu","doi":"10.4236/pp.2022.136014","DOIUrl":"https://doi.org/10.4236/pp.2022.136014","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp;amp; Pharmacy","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134338758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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