Journal of Breast Imaging最新文献

{"title":"Artificial Intelligence and Interval Cancers in Screening Mammography.","authors":"Javier L Galvan, Niki Nourmohammadi, Hannah S Milch, Tiffany T Yu","doi":"10.1093/jbi/wbag042","DOIUrl":"https://doi.org/10.1093/jbi/wbag042","url":null,"abstract":"<p><p>Interval breast cancers are diagnosed between screening rounds. Because they portend a worse diagnosis than screen-detected cancers, decreasing the interval cancer rate is a key measure of screening program effectiveness. Artificial intelligence (AI) tools for breast cancer detection are rapidly emerging with potential to provide earlier detection or even prediction of interval cancers. This article reviews the importance of interval cancers in screening mammography, current evidence for AI performance related to interval cancers, and considerations for interpreting the findings and implications of the current literature.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Male Invasive Pleomorphic Lobular Breast Carcinoma.","authors":"Kyla Manja, Isabella Tondi Resta, Samantha P Zuckerman","doi":"10.1093/jbi/wbaf071","DOIUrl":"10.1093/jbi/wbaf071","url":null,"abstract":"","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"467-469"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatty Breasts and Palpable Lumps: Diagnostic Mammogram Alone May Be Sufficient to Exclude Cancer.","authors":"Dawn C Nwamuo, Grace H Lin, Shivani Gillon, Caitlin M Lydon, Amethyst Leimpeter, Jun Shan, Laurel A Habel, Ninah S Achacoso, Mark Westley, Tony Xu, Denis Mak, Catherine Lee, Dorota Wisner, Vignesh A Arasu","doi":"10.1093/jbi/wbaf080","DOIUrl":"10.1093/jbi/wbaf080","url":null,"abstract":"<p><strong>Objective: </strong>To assess whether diagnostic mammogram alone is sufficient to identify breast cancer in women with a palpable lump and almost entirely fatty breast density.</p><p><strong>Methods: </strong>All 2D full-field diagnostic mammograms performed in a large health system were retrospectively identified for patients assigned \"almost entirely fatty\" breast density from January 2014 through December 2018 who presented with a palpable lump and had at least 2 years of follow-up. Women were excluded if they had a history of breast cancer, ipsilateral surgery, or clinical suspicion of abscess. Other exclusions included axillary lumps, lumps located in the retroareolar or posterior one-third of the breast, and lumps in which the lump marker was visible in only 1 view. The investigators performed image-only review of the diagnostic mammogram, with blinding of the image reports and any ensuing outcomes. Subsequently, the associated US was assessed. Cancer outcomes were ascertained via linkage with the regional tumor registry.</p><p><strong>Results: </strong>A total of 1552 eligible women, mean age 58.7 years ± 13.4, with 1791 lumps, were identified. Of these, 1139 women (73%) had no mammographic correlate, and 86 women (6%) had cancers corresponding to their lump, with 1 cancer having no mammographic correlate. The risk of cancer with no mammographic correlate to the palpable lump was 0.1% (1/1139 ; 95% CI, 0.0-0.3).</p><p><strong>Conclusion: </strong>Diagnostic mammography alone has very low risk of missed cancer and is sufficient for evaluation of palpable symptoms in most women with fatty breast density.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"366-375"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unknown Case: Young Woman With a Palpable Retroareolar Mass.","authors":"Atima Huria, Cherie M Kuzmiak","doi":"10.1093/jbi/wbaf035","DOIUrl":"10.1093/jbi/wbaf035","url":null,"abstract":"","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"460-463"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Cancer Risk and Screening in Active Duty Military Members and Veterans.","authors":"Claire Widule, Andrew Cibulas, Allen Betts, Bethany Niell","doi":"10.1093/jbi/wbag004","DOIUrl":"10.1093/jbi/wbag004","url":null,"abstract":"<p><p>Women represent a growing demographic within the United States military, both active duty and veterans. Breast cancer is the most prevalent non-dermatologic malignancy among female active duty members and veterans. Military service members, specifically women aged 40-59 years, have a higher incidence of breast cancer compared to the general population. Retrospective cohort studies of military members suggest that work-related reproductive factors, including higher frequency of contraceptive use and shorter duration of breastfeeding, may account for at least part of the higher incidence. The impact, if any, of military environmental exposures, such as volatile organic compounds, endocrine disrupting chemicals, pesticides, airborne hazards, and open burn pits, on breast cancer risk is an area of ongoing investigation. This article aims to advance understanding of breast cancer, risk, treatment, and outcomes in military populations while examining current screening practices and ongoing efforts to strengthen prevention and early detection among active duty service members and veterans. The potential of the SERVICE Act to increase screening access in certain military members under age 40 years will be emphasized. Efforts to improve breast cancer prevention and early detection for active duty service members and veterans are imperative for preserving military force readiness and essential for the health of the all-volunteer force of the United States military.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"419-427"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are You MAD (Mammographic Architectural Distortion)? Introducing Subtypes of Synthetic Mammography/Tomosynthesis-Detected Architectural Distortion: Radiating Distortion and Nonradiating Tissue Alteration.","authors":"Steven P Poplack, Meng Hao, Tie Liang, Brittany Z Dashevsky","doi":"10.1093/jbi/wbaf077","DOIUrl":"10.1093/jbi/wbaf077","url":null,"abstract":"<p><strong>Objective: </strong>The goals of this study are to introduce subtypes of mammographic architectural distortion (MAD), designated as radiating distortion (RD) and nonradiating tissue alteration (TA), and evaluate the clinical outcomes, interobserver agreement, and predictive capability of these newly defined subtypes.</p><p><strong>Methods: </strong>Radiating distortion, TA, and 7 mammographic features of MAD were prospectively defined. Three breast radiologists reviewed consecutive screening synthetic mammography/tomosynthesis examinations recalled for MAD between January 1, 2021, and December 31, 2021. Reviewers reclassified MAD as RD, TA, or Neither (RD nor TA) and rated mammographic features. Majority classification was used for analyses. Clinical outcomes were established with ≥2 year follow-up and compared using Fisher's exact test. Logistic regression was performed for feature prediction of MAD subtypes and malignancy. Interobserver agreement was assessed using Gwet's agreement coefficient (AC).</p><p><strong>Results: </strong>Eighty-nine eligible cases were majority classified as RD in 22.5% (20/89), TA in 48.3% (43/89), and Neither in 29.2% (26/89). Malignancy was found in 45% (9/20) of RD, 11.6% (5/43) of TA, and 0% (0/26) of Neither. There were significant differences in diagnostic imaging findings, assessment, and recommendation between subtypes. In all, 80.8% (21/26) of Neither designations represented superimposition. There was substantial interobserver agreement for MAD subtype, Gwet's AC = 0.65. The following features were significantly predictive of RD: ≥7 dense lines, straight-line type, and point convergence. Radiating distortion was predictive of malignancy, and nondense center was associated with benignity in this limited sample.</p><p><strong>Conclusion: </strong>Synthetic mammography/tomosynthesis screen-detected MAD classified as RD and TA demonstrated substantial interobserver agreement and significantly different clinical outcomes.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"406-418"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening Breast MRI and Genetic Testing Utilization in High-risk Population: Analysis of National Health Interview Survey.","authors":"Ishana Maini, Kevin Gilotra, Maedeh Sharifian, Nina Capiro, Gelareh Sadigh","doi":"10.1093/jbi/wbaf084","DOIUrl":"10.1093/jbi/wbaf084","url":null,"abstract":"<p><strong>Objective: </strong>For individuals at increased risk of breast cancer, additional tests, such as screening breast MRI and genetic testing, are recommended. We assessed the utilization of screening breast MRI and genetic testing among high-risk individuals and identified associated patient factors.</p><p><strong>Methods: </strong>This retrospective, cross-sectional study used 2023 National Health Interview Survey data. Women aged 25 or older with at least 1 first-degree relative diagnosed with breast cancer before age 50 were included. A survey weight was applied to generate weighted samples representing national estimates. Multivariable logistic regression analysis was used to identify factors associated with screening breast MRI, genetic test discussions, and genetic test completion.</p><p><strong>Results: </strong>The weighted sample included 6 851 757 women (unweighted n = 920) (mean age, 60.2; 3.1% [199 883/6 486 458] Asian, 14.4% [932 502/6 486 458] Black, 78.1% [5 063 194/6 486 458] White, and 4.4% [290 879/6 486 458] other races). Overall, 12.5% (855 463/6 851 757) were of Hispanic ethnicity. Screening MRI use was reported by 7.9% (506 672/6 417 453) , while 28.8% (1 963 524/6 822 303) discussed and 17.7% (1 209 406/6 830 229) completed genetic testing. Having 2 or more first-degree relatives with breast cancer increased the likelihood of screening MRI (odds ratio [OR], 2.94; 95% CI, 1.56-5.54) and genetic testing completion (OR, 2.74; 95% CI, 1.68-4.48). The odds of discussing genetic testing were lower for Black individuals (OR, 0.43; 95% CI, 0.20-0.91) and those with Medicaid or no insurance (OR, 0.45; 95% CI, 0.23-0.87). Concern about medical bills was associated with lower odds of genetic testing completion (OR, 0.54; 95% CI, 0.33-0.90).</p><p><strong>Conclusions: </strong>Screening breast MRI and genetic testing are underutilized among high-risk women. Expanding insurance coverage and provider education may help increase uptake of recommended screening practices.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"395-405"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12993720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2025-2026 Editor's Recognition Awards.","authors":"Michael A Cohen","doi":"10.1093/jbi/wbag047","DOIUrl":"https://doi.org/10.1093/jbi/wbag047","url":null,"abstract":"","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":"8 4","pages":"353"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ductal Carcinoma In Situ Active Monitoring Trials: Do Eligibility Criteria Identify Patients at Low Risk for Upgrade to Invasive Carcinoma?","authors":"Dana K Ataya, K Ruwani M Fernando, Jasmine Brainerd, Yarelis De La Cruz, Mahmoud Abdalah, Olya Stringfield, Elaheh Sobhani, Natarajan Raghunand, Marilyn Bui, Issam El Naqa, Bethany Lynn Niell","doi":"10.1093/jbi/wbaf085","DOIUrl":"10.1093/jbi/wbaf085","url":null,"abstract":"<p><strong>Background: </strong>Ongoing active monitoring (AM) trials for women with ductal carcinoma in situ (DCIS) are investigating the safety and efficacy of monitoring DCIS lesions vs the current standard of care (surgical treatment). The frequency of upgrade in women undergoing AM for DCIS remains unknown.</p><p><strong>Objective: </strong>To evaluate the frequency of upgrade of DCIS at core-needle biopsy to invasive carcinoma at surgical excision among women who meet eligibility criteria for AM trials.</p><p><strong>Methods: </strong>A retrospective review between 2010 and 2023 was performed of women at an National Cancer Institute-designated comprehensive cancer center with a diagnosis of DCIS at core-needle biopsy who underwent subsequent surgical excision. Medical records were reviewed for clinical presentation, imaging findings, core biopsy, and final surgical pathology. Each patient was evaluated for AM trial eligibility based on published criteria for the LORD, LORIS, and COMET trials. Fisher's exact test compared proportions, with a P-value <.05 considered statistically significant.</p><p><strong>Results: </strong>Of 264 women, 10/264 (3.8%) were eligible for the LORD trial, 24/264 (9.1%) for the LORIS trial, and 64/264 (24.2%) for the COMET trial. Invasive carcinoma was found at surgical excision in 1/10 (10%) patients eligible for the LORD trial, 2/24 (8.3%) for the LORIS trial, and 9/64 (14.1%) for the COMET trial. All occult invasive carcinomas detected at surgical excision in trial-eligible patients were node-negative, with a median size of invasive cancer measuring 3.5 mm (interquartile range, 1-7 mm).</p><p><strong>Conclusion: </strong>A subset of women who meet eligibility criteria for DCIS AM trials are at risk for occult invasive carcinoma, with frequency of upgrade ranging from 8% to 14%.</p><p><strong>Clinical impact: </strong>More precise criteria and predictive biomarkers are needed to better stratify DCIS lesions and exclude women harboring invasive carcinomas from AM regimens.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"387-394"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147345388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tattoo Pigment Migration Within the Breast and Axilla: Radiologic-Pathologic Correlation.","authors":"Elizabeth G Lane, Andy V Phan, Katerina Dodelzon","doi":"10.1093/jbi/wbag022","DOIUrl":"10.1093/jbi/wbag022","url":null,"abstract":"<p><p>Tattoo pigment migration can appear on breast imaging, including mammography and ultrasound, where it may mimic malignant findings. In the literature, 19 cases have been reported. Here, we describe an additional three cases. Most published cases involve women undergoing screening mammography with incidental identification of pigment migration. On imaging, pigment can present as high-density deposits on mammography and echogenic foci on ultrasound, mimicking calcifications. Reported sites of deposition most commonly include axillary lymph nodes and intramammary nodes. If no other morphologic abnormalities are identified and the findings can be confidently attributed to tattoo pigment, biopsy is not necessary. Histopathologically, tattoo pigment appears as aggregates of granular exogenous material. If biopsy is performed and confirms pigment migration, patients may resume risk-appropriate screening without further intervention.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"452-459"},"PeriodicalIF":1.7,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}