发布求助
文献互助 智能选刊 最新文献

Breast Cancer Management最新文献

筛选
英文 中文
Malignant phyllodes tumor of the breast: case report, tumor characteristics, treatment approach 乳腺恶性叶状肿瘤：病例报告、肿瘤特点、治疗方法
IF 0.7
Breast Cancer Management Pub Date : 2021-09-01 DOI: 10.2217/bmt-2020-0036
Ł. Strzępek, Patrycja Ciesielska, Katarzyna Karakiewicz-Krawczyk, A. Czerw
{"title":"Malignant phyllodes tumor of the breast: case report, tumor characteristics, treatment approach","authors":"Ł. Strzępek, Patrycja Ciesielska, Katarzyna Karakiewicz-Krawczyk, A. Czerw","doi":"10.2217/bmt-2020-0036","DOIUrl":"https://doi.org/10.2217/bmt-2020-0036","url":null,"abstract":"Due to the rarity of phyllodes breast tumors (particularly malignant tumors), a limited number of described cases and a lack of randomized studies, we currently do not have absolute guidelines for treating these types of tumors. The following article presents the case of a patient with a malignant phyllodes breast tumor, with numerous local recurrences after primary mastectomy and the effects of treatment. The course of the patient’s disease emphasizes the purposefulness and effectiveness of aggressive surgical treatment. In the article, the authors show that leaving even small abnormalities within the scar just to observation is not good practice; surgeons should try to remove all, even unclear, abnormalities.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44236697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of consanguinity on women's attitudes toward molecular testing of breast cancer in Saudi Arabia 血缘关系对沙特阿拉伯妇女对乳腺癌分子检测态度的影响
IF 0.7
Breast Cancer Management Pub Date : 2021-06-01 DOI: 10.2217/BMT-2021-0002
B. Suliman
{"title":"The impact of consanguinity on women's attitudes toward molecular testing of breast cancer in Saudi Arabia","authors":"B. Suliman","doi":"10.2217/BMT-2021-0002","DOIUrl":"https://doi.org/10.2217/BMT-2021-0002","url":null,"abstract":"","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":"10 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43601916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Male breast cancer diagnosis stages, treatment and survival in Uruguay: a retrospective analysis of a case series 乌拉圭男性癌症的诊断分期、治疗和生存率：一系列病例的回顾性分析
IF 0.7
Breast Cancer Management Pub Date : 2021-06-01 DOI: 10.2217/bmt-2020-0035
N. Camejo, C. Castillo, A. Schiavone, A. Alfonso, D. Amarillo, F. Xavier, Esteban Alvarez, G. Krygier, L. Delgado
{"title":"Male breast cancer diagnosis stages, treatment and survival in Uruguay: a retrospective analysis of a case series","authors":"N. Camejo, C. Castillo, A. Schiavone, A. Alfonso, D. Amarillo, F. Xavier, Esteban Alvarez, G. Krygier, L. Delgado","doi":"10.2217/bmt-2020-0035","DOIUrl":"https://doi.org/10.2217/bmt-2020-0035","url":null,"abstract":"Male breast cancer (MBC) is a rare condition which, while sharing some similarities with breast cancer in women, has a unique disease profile of its own. Aim: To understand the characteristics of MBC and its management in Uruguay. Patients & methods: Retrospective observational study that included patients diagnosed with MBC. Results: 22 cases of MBC were found. The median age at diagnosis was 62.5 years. Symptoms included self-detected lump in 17 patients (77.3%) and nipple retraction in seven (22.7%). Ductal carcinomas of histological grade 2–3 were found in 20 patients (90.9%) and stage I–II disease was most commonly encountered (15 patients, 68.1%). Neoadjuvant chemotherapy, adjuvant chemotherapy, adjuvant radiotherapy and tamoxifen were offered to 16 (73%), 12 (54.5%), 17 (65.4%) and 20 (90.9%) patients, respectively. Conclusion: MBC behaves and is treated in many aspects like postmenopausal breast cancer. Further multi-institutional, prospective studies are needed for better understanding and management of male breast cancers.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42912766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of intraoperative versus preoperative ultrasound-guided wire localization of nonpalpable breast lesions 术中与术前超声引导线定位不可触及乳腺病变的结果
IF 0.7
Breast Cancer Management Pub Date : 2021-05-10 DOI: 10.2217/BMT-2020-0013
P. Wignarajah, V. Papalouka, P. Forouhi
{"title":"Outcomes of intraoperative versus preoperative ultrasound-guided wire localization of nonpalpable breast lesions","authors":"P. Wignarajah, V. Papalouka, P. Forouhi","doi":"10.2217/BMT-2020-0013","DOIUrl":"https://doi.org/10.2217/BMT-2020-0013","url":null,"abstract":"Background: Nonpalpable breast lesions require localization, the gold standard for which is preoperative ultrasound-guided wire localization (PUGWL). Our unit also employs intraoperative ultrasound-guided wire localization (IUGWL). Here we evaluate PUGWL and IUGWL outcomes between 2014 and 2018. Primary outcomes were reoperation rates, complication rates and average specimen weights. Trainee feedback and cost analysis assessed IUGWL viability. Methods: Prospectively recorded data were collected. 511 patients were included (241 PUGWL and 270 IUGWL). Results: Reoperation rates: PUGWL 17.7% versus IUGWL 13.9% (p = 0.28) . Complication rates: PUGWL 5.8% versus IUGWL 6.6% (p = 0.72) . Average specimen weight: PUGWL 34.2 g versus IUGWL 24.3 g (p < 0.0001) . Trainees needed 15 supervised cases to be IUGWL competent. Performing IUGWL saves £289 per localization. Conclusion: IUGWL outcomes are comparable to those of PUGWL. IUGWL is cost-effective, patient-friendly and easy to learn and replicate. IUGWL merits wider dissemination and further planned research.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44002382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-world data of subcutaneous trastuzumab and intravenous pertuzumab as neoadjuvant therapy for localized HER2+ breast cancer in Panama 巴拿马皮下曲妥珠单抗和静脉注射帕妥珠单抗作为局部HER2+乳腺癌症新辅助治疗的真实世界数据
IF 0.7
Breast Cancer Management Pub Date : 2021-05-07 DOI: 10.2217/BMT-2021-0003
Franklin Castillero Rodriguez, O. Castillo-Fernandez, Maria Lim-Law, Cristiane Martin Palacios, L. Montano, Stephani Benitez, Jaime Samudio
{"title":"Real-world data of subcutaneous trastuzumab and intravenous pertuzumab as neoadjuvant therapy for localized HER2+ breast cancer in Panama","authors":"Franklin Castillero Rodriguez, O. Castillo-Fernandez, Maria Lim-Law, Cristiane Martin Palacios, L. Montano, Stephani Benitez, Jaime Samudio","doi":"10.2217/BMT-2021-0003","DOIUrl":"https://doi.org/10.2217/BMT-2021-0003","url":null,"abstract":"The aim of this study is to determine the effectiveness of subcutaneous trastuzumab in combination with intravenous pertuzumab and chemotherapy for patients with HER2-overexpressing localized breast cancer treated in our center. Methods: This was a descriptive, retrospective, real-world study. Results: Of 156 patients, pathological complete response (pCR) was achieved in 64.1%. A multivariate analysis showed a relationship with a negative hormone receptor (HR) expression and a HER2 score of 3+ by immunohistochemistry. Relapse-free survival (RFS) was higher in patients with pCR. Conclusion: Neoadjuvant therapy with dual blockade using intravenous pertuzumab and subcutaneous trastuzumab for HER2+ localized breast cancer in routine clinical practice resulted in a 64.1% pCR rate. Additionally, this outcome was related to a negative HR expression and HER2 overexpression, and correlated with higher relapse-free survival.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41428754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The utility of the tumor markers CA15.3, CEA, CA-125 and CA19.9 in metastatic breast cancer 肿瘤标志物CA15.3、CEA、CA-125和CA19.9在癌症转移中的应用
IF 0.7
Breast Cancer Management Pub Date : 2020-12-01 DOI: 10.2217/bmt-2020-0015
G. Gaughran, N. Aggarwal, B. Shadbolt, R. Stuart-Harris
{"title":"The utility of the tumor markers CA15.3, CEA, CA-125 and CA19.9 in metastatic breast cancer","authors":"G. Gaughran, N. Aggarwal, B. Shadbolt, R. Stuart-Harris","doi":"10.2217/bmt-2020-0015","DOIUrl":"https://doi.org/10.2217/bmt-2020-0015","url":null,"abstract":"Background: Cancer antigen 15.3 (CA15.3) is a commonly used tumor marker (TM) in metastatic breast cancer (MBC) but may not be raised. We assessed CA15.3, carcinoembryonic antigen (CEA), cancer antigen 125 (CA-125) and cancer antigen 19.9 in 193 MBC patients at diagnosis and follow-up. Materials & methods: This TM panel was measured approximately 3 monthly. Median follow-up was 29.3 months. Results: At diagnosis, the following TMs were raised: CA15.3 63.2%, CEA 37.3%, CA-125 45.0% and cancer antigen 19.9 17.3%. CA15.3 became raised later in 28/71. Raised TMs were less common in HER2+ tumors. CA-125 was frequently raised in triple negative tumors and was associated with pleural metastases. More raised TMs correlated with more sites of metastases and shorter survival. Conclusion: CEA and CA-125 showed benefit over CA15.3 alone in MBC and all three should be considered in MBC.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/bmt-2020-0015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45628189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
An evaluation of the risk factors of breast cancer in women in Ilam Province: a case–control study based on hospital 伊兰省女性癌症危险因素评估：基于医院的病例对照研究
IF 0.7
Breast Cancer Management Pub Date : 2020-12-01 DOI: 10.2217/bmt-2020-0026
S. Rahmati, M. Azami, Z. Jaafari, Nasrin Pouratar, Khairollah Asodollahi
{"title":"An evaluation of the risk factors of breast cancer in women in Ilam Province: a case–control study based on hospital","authors":"S. Rahmati, M. Azami, Z. Jaafari, Nasrin Pouratar, Khairollah Asodollahi","doi":"10.2217/bmt-2020-0026","DOIUrl":"https://doi.org/10.2217/bmt-2020-0026","url":null,"abstract":"Aims: The present study aimed to identify the most associated risk factors of breast cancer in Ilam province in 2015–2016. Materials & methods: In this case–control study, the case group consisted of 50 women with breast cancer with a definitive diagnosis from date 23 September 2015 to 22 September 2016. The two groups were group matched in terms of age. Data were collected through interviews and medical records. Results: According to the results, there was a significant relationship between the disease status and variables of family history, history of irregular menstrual cycles, history of breastfeeding, menopausal status, history of oral contraceptive pill consumption, BMI, menarche and number of pregnancies (p < 0.05). Conclusion: Regarding decisive risk factors of breast cancer, more studies with larger sample sizes that take into account more risk factors are necessary.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47985405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Special considerations of breast cancer management in the elderly 老年乳腺癌治疗的特殊考虑
IF 0.7
Breast Cancer Management Pub Date : 2020-12-01 DOI: 10.2217/bmt-2020-0023
Lauren F Cornell, S. Mclaughlin, S. Pruthi, Dawn M. Mussallem
{"title":"Special considerations of breast cancer management in the elderly","authors":"Lauren F Cornell, S. Mclaughlin, S. Pruthi, Dawn M. Mussallem","doi":"10.2217/bmt-2020-0023","DOIUrl":"https://doi.org/10.2217/bmt-2020-0023","url":null,"abstract":"There are increasing numbers of elderly patients diagnosed with breast cancer. These patients are under-represented in available clinical trials, and as such, there are limited evidence-based guidelines for treatment in this population. Elderly patients have unique needs and management strategies should be tailored accordingly. This article reviews available literature regarding breast cancer management and special considerations in elderly patients.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46882451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effects of major lifestyle factors on breast cancer risk: impact of weight, nutrition, physical activity, alcohol and tobacco 主要生活方式因素对乳腺癌风险的影响:体重、营养、体育活动、酒精和烟草的影响
IF 0.7
Breast Cancer Management Pub Date : 2020-09-30 DOI: 10.2217/BMT-2020-0033
Suneela Vegunta, S. Lester, S. Pruthi, Dawn M. Mussallem
{"title":"Effects of major lifestyle factors on breast cancer risk: impact of weight, nutrition, physical activity, alcohol and tobacco","authors":"Suneela Vegunta, S. Lester, S. Pruthi, Dawn M. Mussallem","doi":"10.2217/BMT-2020-0033","DOIUrl":"https://doi.org/10.2217/BMT-2020-0033","url":null,"abstract":"Breast cancer (BC) is the most commonly diagnosed cancer and second most common cause of cancer death in US women. Family history and genetics are well-known BC risk factors, but they only account for 15–20% of BC cases. Therefore, in addition to family history, healthcare providers must consider a woman’s modifiable and nonmodifiable personal risk factors that are associated with an increase in BC risk. The World Cancer Research Fund/American Institute for Cancer Research estimate that 30% of BC cases in the US are preventable. Lifestyle education is imperative given the magnitude of BC occurrence. Evidence supports prevention as an effective, long-term strategy for reducing risk. Healthcare providers are key stakeholders in empowering patients to adopt a healthy lifestyle for primary BC prevention. In this paper, we review the available evidence on modifiable BC risk including weight management, nutrition, physical activity, alcohol and tobacco use and provide strategies to counsel patients on lifestyle modifications.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/BMT-2020-0033","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45767205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Papillary lesions of the breast: a review 乳腺乳头状病变:综述
IF 0.7
Breast Cancer Management Pub Date : 2020-09-28 DOI: 10.2217/BMT-2020-0028
D. Nuñez, F. C. González, Mónica Chapa Ibargüengoitia, Rosaura Eugenia Fuentes Corona, Antonio Carlos Hernández Villegas, Mariana Licano Zubiate, S. E. V. Manjarrez, Carlos Casian Ruiz Velasco
{"title":"Papillary lesions of the breast: a review","authors":"D. Nuñez, F. C. González, Mónica Chapa Ibargüengoitia, Rosaura Eugenia Fuentes Corona, Antonio Carlos Hernández Villegas, Mariana Licano Zubiate, S. E. V. Manjarrez, Carlos Casian Ruiz Velasco","doi":"10.2217/BMT-2020-0028","DOIUrl":"https://doi.org/10.2217/BMT-2020-0028","url":null,"abstract":"Papillary breast lesions are rare breast tumors that comprise a broad spectrum of diseases. Pathologically they present as mass-like projections attached to the wall of the ducts, supported by fibrovascular stalks lined by epithelial cells. On mammogram they appear as masses that can be associated with microcalcifications. Ultrasound is the most used imaging modality. On ultrasound papillary lesions appear as homogeneous solid lesions or complex intracystic lesions. A nonparallel orientation, an echogenic halo or posterior acoustic enhancement associated with microcalcifications are highly suggestive of malignancy. MRI has proven to be useful to establish the extent of the lesion. Core needle biopsy is the gold standard for diagnosis. Surgical excision is usually recommended, although treatment for papillomas without atypia is still controversial.","PeriodicalId":43086,"journal":{"name":"Breast Cancer Management","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/BMT-2020-0028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43397495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信