Male breast cancer diagnosis stages, treatment and survival in Uruguay: a retrospective analysis of a case series

IF 0.4 Q4 ONCOLOGY

Breast Cancer Management Pub Date : 2021-06-01 DOI:10.2217/bmt-2020-0035

N. Camejo, C. Castillo, A. Schiavone, A. Alfonso, D. Amarillo, F. Xavier, Esteban Alvarez, G. Krygier, L. Delgado

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引用次数: 0

Abstract

Male breast cancer (MBC) is a rare condition which, while sharing some similarities with breast cancer in women, has a unique disease profile of its own. Aim: To understand the characteristics of MBC and its management in Uruguay. Patients & methods: Retrospective observational study that included patients diagnosed with MBC. Results: 22 cases of MBC were found. The median age at diagnosis was 62.5 years. Symptoms included self-detected lump in 17 patients (77.3%) and nipple retraction in seven (22.7%). Ductal carcinomas of histological grade 2–3 were found in 20 patients (90.9%) and stage I–II disease was most commonly encountered (15 patients, 68.1%). Neoadjuvant chemotherapy, adjuvant chemotherapy, adjuvant radiotherapy and tamoxifen were offered to 16 (73%), 12 (54.5%), 17 (65.4%) and 20 (90.9%) patients, respectively. Conclusion: MBC behaves and is treated in many aspects like postmenopausal breast cancer. Further multi-institutional, prospective studies are needed for better understanding and management of male breast cancers.

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乌拉圭男性癌症的诊断分期、治疗和生存率：一系列病例的回顾性分析

男性癌症（MBC）是一种罕见的疾病，虽然与女性癌症有一些相似之处，但有其独特的疾病特征。目的：了解乌拉圭MBC的特点及其管理。患者和方法：回顾性观察研究，包括诊断为MBC的患者。结果：发现MBC 22例。诊断时的中位年龄为62.5岁。症状包括17名患者（77.3%）自行发现肿块，7名患者（22.7%）乳头退缩。20名患者（90.9%）发现组织学级别为2-3的导管癌，最常见的是I-II期疾病（15名患者，68.1%）。16名患者（73%）、12名患者（54.5%）接受了新辅助化疗、辅助化疗、，分别为17例（65.4%）和20例（90.9%）。结论：MBC在绝经后乳腺癌症等多方面表现和治疗。需要进一步的多机构前瞻性研究，以更好地了解和管理男性乳腺癌。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Breast Cancer Management ONCOLOGY-

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： Breast Cancer Management (ISSN: 1758-1923) addresses key issues in disease management by exploring the best patient-centered clinical research and presenting this information both directly, as clinical findings, and in practice-oriented formats of direct relevance in the clinic. The journal also highlights significant advances in basic and translational research, and places them in context for future therapy. Breast Cancer Management provides oncologists and other health professionals with the latest findings and opinions on reducing the burden of this widespread disease. Recent research findings and advances clinical practice in the field are reported and analyzed by international experts. The journal presents this information in clear, accessible formats. All articles are subject to independent review by a minimum of three independent experts. Unsolicited article proposals are welcomed and authors are required to comply fully with the journal’s Disclosure & Conflict of Interest Policy as well as major publishing guidelines, including ICMJE and GPP3. Coverage includes: Diagnosis and imaging, Surgical approaches, Radiotherapy, Systemic therapies, Cancer clinical trials, Genetic aspects of disease, Personalized medicine, Translational research and biomarker studies, Management of psychological distress, Epidemiological studies, Pharmacoeconomics, Evidence-based treatment guidelines.