Journal of Pediatrics Review最新文献_第8页

Gastrointestinal Symptoms and Hepatopancreatic Involvement in COVID-19 Children: A Narrative Review COVID-19儿童胃肠道症状和肝胰腺受累:叙述性综述

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-01-01 DOI: 10.32598/jpr.10.specialissue.344.2

S. Mehrabani, M. Nikpour, L. Moslemi

{"title":"Gastrointestinal Symptoms and Hepatopancreatic Involvement in COVID-19 Children: A Narrative Review","authors":"S. Mehrabani, M. Nikpour, L. Moslemi","doi":"10.32598/jpr.10.specialissue.344.2","DOIUrl":"https://doi.org/10.32598/jpr.10.specialissue.344.2","url":null,"abstract":"Background: To the best of our knowledge, limited studies explored gastrointestinal (GI) symptoms and hepatopancreatic involvement in children with coronavirus disease 2019 (COVID- 19) infection. Objectives: This review study aimed to evaluate the GI symptoms and abnormal liver and pancreas function in children with COVID-19 infection. Methods: In this review study, databases of Scopus, PubMed, Google Scholar, and Web of Science were searched using the relevant keywords of “COVID-19,” “children,” “gastrointestinal,” “liver,” and “pancreas.” Descriptive and cross-sectional studies were reviewed in the current study, with the main focus on GI symptoms and elevated liver enzymes in children with COVID-19 infection. Results: Overall, 27 studies from countries of Iran, Spain, Turkey, Italy, and the United States were selected. Although the prevalence of GI symptoms varied in different studies, our review showed that most children with COVID-19 infection experienced GI symptoms. In addition to GI symptoms, there is the possibility of elevated liver enzymes, such as alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, and creatine phosphokinase in children with COVID-19 infection. Conclusions: COVID-19 infection may present various GI, hepatic, and pancreatic manifestations in children. The difference in the prevalence of these symptoms can probably be attributed to the geographical region of the study and the history of the disease.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41593556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Pleural Effusion in a Child With COVID-19: A Case Report COVID-19患儿胸腔积液1例

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-01-01 DOI: 10.32598/jpr.10.specialissue.935.1

M. Abedini, P. Ataei, M. Ghaderi, Avat Karimi, Farima Zakaryaei

引用次数: 0

Respiratory Manifestations of COVID-19 in Children: A Narrative Review 儿童新冠肺炎的呼吸道表现：叙述性回顾

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-01-01 DOI: 10.32598/jpr.10.specialissue.309.1

F. Masiha, Abbas Dabbaghzadeh, Negar Ghaffari, J. Ghaffari

{"title":"Respiratory Manifestations of COVID-19 in Children: A Narrative Review","authors":"F. Masiha, Abbas Dabbaghzadeh, Negar Ghaffari, J. Ghaffari","doi":"10.32598/jpr.10.specialissue.309.1","DOIUrl":"https://doi.org/10.32598/jpr.10.specialissue.309.1","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID‐19, the seventh coronavirus) is a new infectious disease that spread worldwide and rapidly became a pandemic. COVID‐19 is rare in children and often asymptomatic. The respiratory system is mainly involved in COVID-19 infection. Objectives: This study aimed to review respiratory manifestations in children with COVID-19. Methods: We searched for studies published from January 2020 to January 2021 in PubMed, Google Scholar, and Scopus in English. The search words were “2019-nCoV,” “novel coronavirus,” “COVID-19,” “SARS-CoV-2,” “severe acute respiratory syndrome coronavirus 2,” “children,” “child,” “infant,” “teenager,” “adolescent,” “pediatric,” and “neonate.” Results: Cough was a common symptom in our study (18.8%-100%, mean=64%). Pneumonia prevalence in children with COVID-19 is 11%-67% (mean=46%). Mild respiratory symptoms (14% - 60%) and severe respiratory distress syndromes (14%) were reported in some studies. Upper respiratory tract infection (URTI) was reported in 4 studies ranging from 11.1% to 34.4% (mean=24.1%). Ground-glass opacities (GGO) was reported in 12.2% to 81% of cases (mean=49.01%). Isolated consolidations were reported in 17% and 58% of patients in two studies. Enhanced lung texture was reported in 1.3% to 50% (mean=20.07%) of patients. Bilateral patchy shadowing was seen in 12.3% to 68% (mean=46.58%) of patients. Conclusions: Cough is the most common manifestation of respiratory system involvement in children with COVID-19. GGO and bilateral patchy involvement are the most common finding on lung CT scans in children with COVID-19.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44714262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran 伊朗儿童COVID-19感染的流行病学研究

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-01-01 DOI: 10.32598/jpr.10.specialissue.919.2

M. Naseri, G. Khademi, Majid Khadem Rezaeian, Shahabaldin Sorouri, M. Sezavar

{"title":"COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran","authors":"M. Naseri, G. Khademi, Majid Khadem Rezaeian, Shahabaldin Sorouri, M. Sezavar","doi":"10.32598/jpr.10.specialissue.919.2","DOIUrl":"https://doi.org/10.32598/jpr.10.specialissue.919.2","url":null,"abstract":"Background: COVID-19 is a highly infectious and contagious disease. Since the outbreak of COVID-19, most studies on children have focused on the incidence and prognosis of the disease, and few studies have investigated the epidemiological characteristics of the disease. Objectives: This study aimed to investigate some epidemiological aspects of the disease in children with COVID-19. Methods: We examined children with COVID-19 (under 18 years) hospitalized in the North East of Iran from the beginning of the outbreak until the end of September 2020. Study information was collected from patients’ medical records and interviews with their parents. We recorded demographic data; history of diseases and taking medicine in children; educational, occupational, and smoking status of parents; patients’ residence conditions; and any report of COVID-19 in patients’ families and relatives. Results: Of 107 children studied, 57% were male, and 52.3% had no underlying disease. The mean age of patients was 67 months. The Mean±SD weight of the children was 20.36±13.75 kg, and their Mean±SD length of hospital stay was 9±8 days. Multisystem inflammatory syndrome in children (MIS-C) was observed in 34.6% of patients, and its relationship with death was highly significant (P=0.001). The length of hospital stay was influenced by the history of medication consumption (P=0.013) and underlying disease (P=0.001), and its increase was associated with an increased risk of MIS-C (P=0.032) and death (P=0.047). Conclusions: Male sex, length of hospital stay, and MIS-C were identified as risk factors associated with worsening the outcome of COVID-19 disease in children.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41424533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Related Eye Manifestations: A Narrative Review COVID-19相关眼部表现:述评

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-01-01 DOI: 10.32598/jpr.10.specialissue.970.1

Yousef Alizadeh, A. Medghalchi, Reza Soltani Moghaddam, Hasan Behboodi, Ebrahim Azaripour, Amirhossein Tamimi

{"title":"COVID-19 Related Eye Manifestations: A Narrative Review","authors":"Yousef Alizadeh, A. Medghalchi, Reza Soltani Moghaddam, Hasan Behboodi, Ebrahim Azaripour, Amirhossein Tamimi","doi":"10.32598/jpr.10.specialissue.970.1","DOIUrl":"https://doi.org/10.32598/jpr.10.specialissue.970.1","url":null,"abstract":"Background: The COVID-19 pandemic has affected human beings in many ways. The presence of SARS-CoV-2 in conjunctival cells and its secretion has been reported in the literature. In addition, there were significant reports of ocular complications that coincide with COVID-19 disease. This study aims to evaluate the COVID-19 symptoms associated with ocular manifestations. Context: Evidence Acquisition: We conducted a literature search with the keywords of “SARS-CoV-2,” “COVID-19,” “nCoV-19,” “SARS,” “MERS,” and “severe acute respiratory syndrome coronavirus‐2” combined with key terms of “eye,” “ocular,” “ophthalmologic,” “ophthalmic,” “conjunctivitis,” “conjunctiva,” “uveitis,” “optic,” “retina,” “retinitis,” “cornea,” “scleritis,” and “glaucoma” in LitCovid hub, PubMed, Scopus, ISI Web of Sciences, Cochrane, and Embase databases, as well as non-review articles. Results: The COVID-19 pandemic and its lockdown has drastically changed people’s lifestyles and health. The pandemic has also affected medical performance in various fields, including ophthalmology. This study summarized some findings in several areas of ophthalmology, including: 1) The surface of the eye (conjunctivae, cornea), 2) Intraocular manifestations (uveitis, retinitis), 3) Neurological features of the eye, 4) COVID-related ocular coagulopathy (retinal vein occlusion), 5) Ophthalmological follow-up failure due to lockdown, 6) Rare manifestations, and 7) Diagnostic and protective measures. Data collection about the ophthalmological experience was done during this respiratory viral infection pandemic, and the most relevant literature was reviewed. Conclusions: Data findings showed a wide range of ocular manifestations and complications associated with COVID-19 and its pandemic. Conjunctivitis is the most common ocular manifestation of COVID-19.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49222431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

COVID-19 – Associated Acute Transverse Myelitis in Children: A Case Report and Review of Literature 儿童COVID-19相关急性横断面脊髓炎1例报告及文献复习

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-01-01 DOI: 10.32598/jpr.10.specialissue.992.2

M. Naseri, F. Ashrafzadeh, G. Khademi, Shima Imannezhad, S. Sorouri, M. Sezavar

引用次数: 2

Clinical Characteristics of Multisystem Inflammatory Syndrome in Children and Young Adults With COVID-19: A Rapid Systematic Review 新冠肺炎儿童和青年多系统炎症综合征的临床特征：快速系统评价

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-01-01 DOI: 10.32598/jpr.10.specialissue.1008.1

Manish Kumar, S. Swarnim, Pallavi Pallavi

{"title":"Clinical Characteristics of Multisystem Inflammatory Syndrome in Children and Young Adults With COVID-19: A Rapid Systematic Review","authors":"Manish Kumar, S. Swarnim, Pallavi Pallavi","doi":"10.32598/jpr.10.specialissue.1008.1","DOIUrl":"https://doi.org/10.32598/jpr.10.specialissue.1008.1","url":null,"abstract":"Background: The associated multisystem inflammatory syndrome in children (MIS-C) with coronavirus disease (COVID-19) is a novel syndrome that has phenotypic similarity to Kawasaki disease (KD). Objectives: This study systematically reviewed the demographic profile, clinical spectrum, treatment options, and outcomes of children and young adults under 21 years of age suffering from MIS-C. Methods: PubMed and Embase databases were searched from inception to July 3, 2020. A total of 39 studies involving 799 participants were included in the review. Critical appraisal of included studies was done using Joanna Briggs Institute Critical Appraisal Checklist for studies reporting prevalence data. A narrative synthesis was performed through descriptive summaries of demographic variables, clinical features, investigations, treatment details, and clinical outcomes. Results: The main complaints of the patients were fever (96.4%) followed by gastrointestinal symptoms. Serological evidence of preceding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was documented in 79.1% of the participants. Ventricular dysfunction (50.2%) was the most common echocardiographic finding. Intensive care was required for 77% of included participants, with 27.2% being mechanically ventilated. Also, 78.1% of the participants received intravenous immunoglobulins. The overall mortality rate was 1.5%. Conclusions: MIS-C associated with COVID-19 clinically resembles a hyperinflammatory state. More extensive studies will help in better defining this entity and delineating its phenotypic subtypes.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47133449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Genetics of Legg-Calvé-Perthes Disease: A Review Study legg - calv<s:1> - perthes病的遗传学研究综述

IF 0.4

Journal of Pediatrics Review Pub Date : 2021-10-01 DOI: 10.32598/JPR.9.4.964.1

Samira Asadollahi, H. Neamatzadeh, N. Namiranian, M. Sobhan

引用次数: 2

Vitamin D Intoxication in Three Children With Varied Manifestations: A Case Series and Review 三例不同表现的儿童维生素D中毒病例系列及综述

IF 0.4

Journal of Pediatrics Review Pub Date : 2021-10-01 DOI: 10.32598/JPR.9.4.937.1

M. Behera, C. Behera, S. Patnaik, B. Meher

{"title":"Vitamin D Intoxication in Three Children With Varied Manifestations: A Case Series and Review","authors":"M. Behera, C. Behera, S. Patnaik, B. Meher","doi":"10.32598/JPR.9.4.937.1","DOIUrl":"https://doi.org/10.32598/JPR.9.4.937.1","url":null,"abstract":"Background: Inadvertent and erroneous prescription of vitamin D beyond the recommended dosage and route of administration can cause vitamin D intoxication in children. Infants are particularly vulnerable to such toxicity. Clinical features are due to hypercalcemia, ranging from mild to life-threatening symptoms. We report two infants and one child who had varied manifestations due to hypercalcemia resulting from empirical treatment with high doses of vitamin D. We discuss the management strategies in these cases along with a brief review of the literature. Case Presentation: Our first case was a 10-month-old infant who presented with fever, vomiting, and failure to thrive. Our detailed clinical examination and investigation revealed hypertension and bilateral nephrocalcinosis along with urinary tract infection. The second child was a 2-year-old girl with severe hypercalcemia with clinical features mimicking acute bacterial meningitis. The third infant had mild symptoms like constipation and irritability, and investigations showed moderate hypercalcemia. All had a history of inappropriate vitamin D administration, either in oral or parenteral form, and they were all successfully treated. Conclusions: These case series highlight the importance of proper dosage, avoidance of parenteral route, along with appropriate clinical and biochemical monitoring during the course, whenever a dose of vitamin D is advised.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43059305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orbital Lymphangioma: A Case Report and Review of Management Modalities 眼眶淋巴管瘤1例报告及治疗方法综述

IF 0.4

Journal of Pediatrics Review Pub Date : 2021-10-01 DOI: 10.32598/JPR.9.4.449.1

N. Jafari, R. Jafari

{"title":"Orbital Lymphangioma: A Case Report and Review of Management Modalities","authors":"N. Jafari, R. Jafari","doi":"10.32598/JPR.9.4.449.1","DOIUrl":"https://doi.org/10.32598/JPR.9.4.449.1","url":null,"abstract":"Background: Generally presents in childhood, orbital lymphangioma is an uncommon unencapsulated vascular malformation of the lymphatic system. These benign cystic lesions represent 1%-4% of all orbital masses and may appear after an upper respiratory infection or minor trauma. Because of its nature, the management can be challenging and depends on the clinical presentation. We report an 8-year-old boy with orbital lymphangioma presented with acute proptosis. Then, we discuss different features of this disorder plus its management Case Presentation: An 8-year-old boy was presented with sudden left eye proptosis. He had normal visual acuity and color vision without ocular pain or diplopia. An infiltrative and diffused intraconal plus extraconal mass was detected in orbital computed tomography. Contrast-enhanced MRI revealed a multilobulated infiltrative heterogeneous lesion with fluid-fluid levels. The diagnosis was made on imaging, and he went under treatment with an oral corticosteroid. The symptoms were entirely resolved, and no recurrence occurred during the follow-up. There are several surgical and nonsurgical therapies for orbital lymphangioma. Still, the priority is conservative management, such as sclerotherapy (including OK-432, doxycycline, sodium tetradecyl sulfate, etc.), bleomycin, carbon dioxide laser, systemic corticosteroids, and so on. Conclusions: In most cases, the current imaging methods make a noninvasive diagnosis of orbital lymphangioma possible. Conservative management should be considered the first treatment.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44944341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1