Journal of Pediatrics Review最新文献_第6页

The Prevalence of Obesity in Iranian Children: A Systematic Review and Meta-analysis 伊朗儿童肥胖患病率的系统评价和荟萃分析

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-04-01 DOI: 10.32598/jpr.10.2.875.2

H. Akbari, M. Mohammadi

{"title":"The Prevalence of Obesity in Iranian Children: A Systematic Review and Meta-analysis","authors":"H. Akbari, M. Mohammadi","doi":"10.32598/jpr.10.2.875.2","DOIUrl":"https://doi.org/10.32598/jpr.10.2.875.2","url":null,"abstract":"Background: The prevalence of childhood obesity has been on an increasing trend in the world during the past decades, with studies in Iran showing different and inconsistent prevalence rates. Objectives: This study was done to determine the prevalence of obesity in children through a meta-analysis approach. Methods: This study was done to determine the prevalence of obesity in children through a meta-analysis approach from January 2000 to January 2021. Articles related to the subject were obtained by searching Scopus, ScienceDirect, SID, Magiran, Barakat Knowledge Network System, Medline (PubMed), and Google Scholar databases. The heterogeneity of the studies was evaluated using the I2 index and the data were analyzed by Comprehensive Meta-analysis software. Results: In a study on 2,637,912 individuals aged 2-15 years, the overall prevalence of obesity in Iranian children was 11.4% (95% CI: 9.4-13.7%) based on a meta-analysis. Also, in order to investigate the effects of potential factors (sample size and year of study) on the heterogeneity of obesity prevalence in Iranian children, meta-regression was used. It was reported that the prevalence of obesity in Iranian children decreased and increased with increasing sample size and increasing years of the study, respectively, and both were significantly different from each other (P<0.05). Conclusions: Considering the high prevalence of obesity in Iranian children, it is necessary for health policymakers to take effective educational measures.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48984935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total Insights on Goiter in Children: A Mini-review 儿童甲状腺肿的全面见解:一个小型综述

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-04-01 DOI: 10.32598/jpr.10.2.967.1

Setila Dalili, D. Zamanfar, A. Hassanzadeh Rad, Saber Najafi Chakoosari

{"title":"Total Insights on Goiter in Children: A Mini-review","authors":"Setila Dalili, D. Zamanfar, A. Hassanzadeh Rad, Saber Najafi Chakoosari","doi":"10.32598/jpr.10.2.967.1","DOIUrl":"https://doi.org/10.32598/jpr.10.2.967.1","url":null,"abstract":"Background: Thyroid disorder is one of the main endocrine problems in childhood. In children with thyroid disorders, goiter is common. Objectives: In this mini-review, the authors aimed to present total insights on goiter in children. Methods: This is a mini-review about total insights on goiter in children. This review included articles assessing goiter in children. Web of Science, PubMed, and Google Scholar were investigated to find appropriate articles regarding goiter in children from 1988 to 2021. The keywords were thyroid, goiter, hyperthyroidism, hypothyroidism, and thyroid nodule. The authors included all study types assessing the pathophysiology, evaluation, and treatment of goiter in childhood. Results: Through taking the medical history and performing a physical examination, clinicians can differentiate types of goiter, including diffuse or nodular toxic or non-toxic, which can present themselves in euthyroid, hypothyroid, and hyperthyroid states. When taking a medical history, clinicians have to ask patients about their food intake, place of residence, and nutrient deficiencies to abstain from goitrogens. Diverse treatment methods are required for goiter in euthyroidism, hypophyroidism, and hyperthyroidism. In patients with euthyroidism, whenever there is iodine deficiency, a history of irradiation to the neck, or Hashimoto’s disease, suppressive therapy is needed. Both clinical and subclinical hypothyroidism need levothyroxine. Besides, in hyperthyroidism, antithyroid drugs, iodine therapy, or surgery are needed. Both clinical and subclinical hypothyroidism need levothyroxine. Conclusions: In hyperthyroidism, antithyroid drugs, iodine therapy, or surgery are needed. Based on the importance of managing goiter in children, clinicians have to consider food intake, vitamin deficiency, and iodine status in these patients.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47931305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrocardiography Adverse Effects Systemic Glucantime in a Child With Cutaneous Leishmaniosis: A Case Report and Brief Review 小儿皮肤利什曼病中系统性葡聚糖的心电图不良反应:1例报告及简要回顾

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-04-01 DOI: 10.32598/jpr.10.2.913.3

Y. Ghandi, S. Mehrabi, M. Safaei

{"title":"Electrocardiography Adverse Effects Systemic Glucantime in a Child With Cutaneous Leishmaniosis: A Case Report and Brief Review","authors":"Y. Ghandi, S. Mehrabi, M. Safaei","doi":"10.32598/jpr.10.2.913.3","DOIUrl":"https://doi.org/10.32598/jpr.10.2.913.3","url":null,"abstract":"Background: Antimonial compounds are the most common choice for the treatment of cutaneous Leishmaniosis (CL). Antimonial toxicities are common and cardiac toxicity is one of them, which leads to the electrocardiogram (ECG) changes. In this study, ECG changes in a patient with CL, who received systemic glucantime, were evaluated. Objectives: A 7-year-old girl was admitted to Amir-Kabir Hospital with the complaint of skin lesions (CL) on her left leg from ten months ago. The patient had received glucantime (10-20mg/kg/day) as a treatment for two 15-day periods and unfortunately, she had not responded to the treatment. Due to the cardiac side effects of glucantime, cardiology consultation was requested and an ECG was performed for the patients during the administration of treatment for the third time. Several ECG changes were detected, including first-degree block, right bundle branch block (RBBB), and QTc prolongation. The cardiologist stopped the treatment with glucantime to improve the ECG changes, and an ECG was taken every week. Even though prolonged QT interval and RBBB improved after a month, the first-degree block was present for ten months. Conclusions: ECG monitoring is necessary prior to and during the treatment with this drug. Moreover, RBBB has not been commonly reported in other studies. Thus, it should be considered as one of the cardiac side effects of glucantime and needs more attention.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44592019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emergency Evacuation Related Challenges in Specialized Hospitals for Children and Neonates: A Narrative Review 儿童和新生儿专科医院紧急疏散相关挑战:述评

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-04-01 DOI: 10.32598/jpr.10.2.1037.1

Mohammad Javad Ghazanfari, Samad Karkhah, T. Yaghoubi

{"title":"Emergency Evacuation Related Challenges in Specialized Hospitals for Children and Neonates: A Narrative Review","authors":"Mohammad Javad Ghazanfari, Samad Karkhah, T. Yaghoubi","doi":"10.32598/jpr.10.2.1037.1","DOIUrl":"https://doi.org/10.32598/jpr.10.2.1037.1","url":null,"abstract":"Background: In recent years, the number of emergencies in hospitals has increased. Hospitals are one of the main assets for successful disaster management. One of the significant challenges in a disaster is the evacuation of training wards. There are anatomical and physiological differences between adults and children that make children more vulnerable to accidents and disasters. Rapid transfer of sick children on a large scale has always been challenging in this respect. Objectives: This study pursued the goal to determine the challenges of emergency evacuation in specialized hospitals for children and neonates. Methods: Searching online databases, such as Google Scholar, PubMed, Scopus, and Web of Science was done from December 1 to December 20, 2021. The keywords used for the search were based on Medical Subject Headings (MESH) and were combined with other keywords, including evacuation, disaster, pediatric, and patient transfer. All English language studies consistent with the study goal (emergency evacuation challenges in specialized hospitals for children and neonatal) were included in this study. Results: Out of 2,145 studies, the full text of 11 studies was finally reviewed. The measures taken during natural disasters are divided into three levels: local, state, and national. Emergency evacuation challenges are also divided into five categories: communication, training, transportation, equipment and energy, and management. Conclusions: This study provided essential perspectives for developing appropriate intervention strategies for the managers and policymakers of health care systems to better prepare in case of natural disasters breaking out in children and neonatal wards.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41846953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Immunoglobulins Status In Splenectomized And Non-Splenectomized Patients With Major Beta-Thalassemia 严重β地中海贫血脾切除和非脾切除患者免疫球蛋白状态的比较

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-04-01 DOI: 10.32598/jpr.10.2.951.2

G. Miri-Aliabad, A. Rezaeifar, Mahdi Salarzaei

{"title":"Comparison of Immunoglobulins Status In Splenectomized And Non-Splenectomized Patients With Major Beta-Thalassemia","authors":"G. Miri-Aliabad, A. Rezaeifar, Mahdi Salarzaei","doi":"10.32598/jpr.10.2.951.2","DOIUrl":"https://doi.org/10.32598/jpr.10.2.951.2","url":null,"abstract":"Background: Thalassemia is one of the most prevalent genetic disorders globally, and infections are one of the major causes of death in these patients. Various studies have attributed the increased susceptibility to bacterial infections in thalassemia patients to changes in their immunological status. Objectives: This research aimed to measure serum levels of immunoglobulins (Igs) in Thalassemia Major (TM) patients and in the control group. Methods: The study included forty TM patients (20 splenectomized and 20 non-splenectomized) and 20 healthy participants (the control group). Three groups were matched for age and gender. Mean serum levels of immunoglobulins (IgG, IgA and IgM) were measured for all individuals by ELISA. P<0.05 was considered the significance level. Results: Increased serum IgG and IgA levels and significantly reduced serum IgM levels were observed in the splenectomized patients compared to the non-splenectomized ones. A comparison of the study groups revealed that serum IgG and IgA levels in the splenectomized patients and the mean serum IgM and IgG levels in the non-splenectomized patients were higher than those of the healthy participants. The mean serum IgM levels in the splenectomized patients and the mean serum IgG levels in the non-splenectomized patients were lower than those of the control group. Conclusions: The results showed that splenectomy could change the immunological status of thalassemia patients. Nevertheless, the exact mechanism for this change was not clear. Studying the serum levels of immunoglobulins might be useful in determining the severity of infections in TM patients.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47534338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Nutrition Support among Critically Ill Pediatric Patients: The Current Practice 危重儿科患者的营养支持:当前的实践

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-04-01 DOI: 10.32598/jpr.10.2.919.3

F. Roudi, M. Sezavar, M. Naseri, Fahimeh Azadeh, G. Khademi

{"title":"Nutrition Support among Critically Ill Pediatric Patients: The Current Practice","authors":"F. Roudi, M. Sezavar, M. Naseri, Fahimeh Azadeh, G. Khademi","doi":"10.32598/jpr.10.2.919.3","DOIUrl":"https://doi.org/10.32598/jpr.10.2.919.3","url":null,"abstract":"Background: Pediatric Intensive Care Unit (PICU) admitted patients are considered as a nutritionally high-risk population, for whom optimum energy and nutrient delivery is an important treatment strategy preventing organ dysfunction and subsequently poor clinical outcomes. Objectives: The present study aimed to investigate the nutritional adequacy indices and their probable relations to clinical outcomes in critically ill children. Methods: This project was a retrospective cross-sectional study carried out at the Akbar Children’s Hospital, Mashhad, Iran. All critically ill children with PICU stay >48 hours during May-June 2019 were enrolled. Age, gender, medical diagnosis, nutritional status, energy and protein requirements and deliveries, and clinical outcomes of patients were extracted. Results: Seventy-one patients were included, among whom 39 subjects (54.9%) were male. The prevalence of malnutrition was 45.3% and 52.4% in PICU patients with surgical and non-surgical underlying diseases, respectively. There were significant associations between the nutritional status of the patients (upon the PICU admission time), infection, and mortality rate. Mean±SEM values of the estimated energy requirement and delivered energy were 85.7±1.6 and 68.3±2.1 kcal/kg/d, respectively. In addition, the estimated protein requirement and protein delivery were 2.5±0.08 and 1.8±0.03 gr/kg/d, respectively. Energy intake had a negative association with infection rate and lower protein delivery was negatively associated with prolonged duration of mechanical ventilation. Conclusions: Significant associations were found between energy/protein delivery and some clinical outcomes. The findings indicated the necessity of immediate further studies on the efficacy of different nutritional interventions as well as monitoring of optimal nutrition support barriers in critically ill children.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46130772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Growth in Pediatric Chronic Renal Failure: A Narrative Review 儿童慢性肾衰竭的生长管理:叙述性回顾

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-04-01 DOI: 10.32598/jpr.10.2.584.4

Manijeh Tabrizi, Seyyedeh Azadeh Hoseini Nouri, M. Zarkesh, A. Hassanzadeh Rad, Elham Hashemi Dehkordi, Setila Dalili

{"title":"Management of Growth in Pediatric Chronic Renal Failure: A Narrative Review","authors":"Manijeh Tabrizi, Seyyedeh Azadeh Hoseini Nouri, M. Zarkesh, A. Hassanzadeh Rad, Elham Hashemi Dehkordi, Setila Dalili","doi":"10.32598/jpr.10.2.584.4","DOIUrl":"https://doi.org/10.32598/jpr.10.2.584.4","url":null,"abstract":"Background: Growth impairment is a common problem in Chronic Kidney Disease (CKD) children. Approximately 40% of children with CKD have a reduced final height. Growth impairment affects school attendance, duration of hospitalization, adult height, and even risk of death. Objectives: Various studies have shown that patients with moderate to severe growth failure have higher mortality rates (three folds) than those with normal growth. This narrative review aimed to define the management of growth in pediatric chronic renal failure. Methods: This study was conducted through a literature search with the keywords of chronic renal failure, kidney transplant, Glomerular Filtration Rate (GFR) combined with growth, short stature, and growth hormone using PubMed, Scopus, Web of Sciences, Cochrane, and Embase databases. Results: Growth impairment in children with CKD occurs due to diverse etiologies, such as uremia, anemia, metabolic acidosis, etc. It becomes more prominent in GFR<75 ml/min/1.73 m2. Growth hormone (GH) therapy seems to be a safe and effective therapeutic modality consequent to the correction of associated metabolic disturbances. Conclusions: This study indicated that pretransplant GH therapy in children with CKD and its temporary discontinuation at kidney transplantation up to one year after transplantation leads to improved growth velocity. Therefore, it seems that considering GH therapy in children with CKD is mandatory.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46890065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of a Novel Mutation in an Iranian Family with 17-β Hydroxysteroid Dehydrogenase Type 3 Deficiency; A case series 伊朗17-β羟基类固醇脱氢酶3型缺乏家族新突变的鉴定案例系列

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-03-06 DOI: 10.32598/jpr.10.1.960.2

A. Heidari, A. Homaei, F. Saffari

引用次数: 0

Effect of vitamin D supplementation on serum lipid profiles in children and adolescence: A meta-analysis 补充维生素D对儿童和青少年血脂水平的影响：一项荟萃分析

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-03-06 DOI: 10.32598/jpr.10.1.987.1

B. Amiri, K. Namakin, M. Soltani, Sameep S. Shetty, S. Riahi

{"title":"Effect of vitamin D supplementation on serum lipid profiles in children and adolescence: A meta-analysis","authors":"B. Amiri, K. Namakin, M. Soltani, Sameep S. Shetty, S. Riahi","doi":"10.32598/jpr.10.1.987.1","DOIUrl":"https://doi.org/10.32598/jpr.10.1.987.1","url":null,"abstract":"Background: Vitamin D deficiency is an important risk factor for some chronic disease. Some reports suggested that there is an interrelationship between lipids and cholecalciferol. Objectives: This meta-analysis was conducted to summarize the existing evidence of randomized controlled trial (RCTs) to evaluate the effect of vitamin D supplementation on lipid profiles in children and adolescents. Methods: In this systematic review and meta-analysis data base such as Web of Science, PubMed, Scopus, Google Scholar, EMBASE, Science Direct, Magiran, SID were searched for studies prior up to December 21st, 2019. This study was conducted according to PRISMA guidelines. I-square was used to measure the existing heterogeneity through included articles. Considering heterogeneity among articles, random-effect models were applied to pool standardized mean differences (SMD) as overall effect size. P-value <0.05 was considered statistically significant. The analyses were conducted by STATA v 14.0. Study eligibility criteria included Children and adolescents (<18 years) and evaluated the association between vitamin D and lipid profile. Results: A total of 13 trials (number of participant=173) were included in the current meta-analysis. The SMD is 0.23, the vitamin D supplementation is associated with significant slight increase in high-density lipoproteins (HDL) levels in children and adolescent (SMD 0.23; 95% CI, 0.02, 0.45, P= 0.036; I2= 57.7%, Egger’s P=0.554). We found no significant association between vitamin D supplementation and LDL-cholesterol levels (SMD -0.10; 95% CI, − 0.29, 0.09, P = 0.310 ; I2 = 0.0%, Egger’s P=0.689), Total cholesterol levels (SMD –0.01; 95% CI, − 0.20, 0.18, P = 0.926 ; I2 = 0.0%, Egger’s P=0.005) and triglycerides levels (SMD -0.10; 95% CI, − 0.22, 0.02, P = 0.093 ; I2 = 0.0%, Egger’s P=0.160). Conclusions and implications: vitamin D could marginally increase HDL level, without any significant effect on LDL-C, TG, and TC levels.","PeriodicalId":43059,"journal":{"name":"Journal of Pediatrics Review","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47282893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Predisposing factors of cerebral edema in Pediatric Diabetic Ketoacidosis: A systematic review 儿童糖尿病酮症酸中毒脑水肿的易发因素：系统综述

IF 0.4

Journal of Pediatrics Review Pub Date : 2022-03-06 DOI: 10.32598/jpr.10.1.994.1

H. Jafari, Pooneh Dadashian, J. Ghaffari, D. Zamanfar

引用次数: 0