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The role of healthcare provider trust in reducing COVID-19 vaccine hesitancy among caregivers in the Philippines 医疗保健提供者信任在减少菲律宾护理人员COVID-19疫苗犹豫中的作用
IF 2.5
Vaccine: X Pub Date : 2026-08-01 Epub Date: 2026-07-17 DOI: 10.1016/j.jvacx.2026.100877
Darin Jan C. Tindowen
{"title":"The role of healthcare provider trust in reducing COVID-19 vaccine hesitancy among caregivers in the Philippines","authors":"Darin Jan C. Tindowen","doi":"10.1016/j.jvacx.2026.100877","DOIUrl":"10.1016/j.jvacx.2026.100877","url":null,"abstract":"","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"31 ","pages":"Article 100877"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148634281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Science-based exit from stringent countermeasures against COVID-19: Mortality prediction using immune landscape between 2021 and 2022 in Japan” [Vaccine: X 20 (2024) 100547] “基于科学退出严格的COVID-19对策:日本2021年至2022年免疫景观死亡率预测”的勘误表[疫苗:X 20 (2024) 100547]
IF 2.5
Vaccine: X Pub Date : 2026-08-01 Epub Date: 2026-06-30 DOI: 10.1016/j.jvacx.2026.100865
Taishi Kayano, Misaki Sasanami, Hiroshi Nishiura
{"title":"Corrigendum to “Science-based exit from stringent countermeasures against COVID-19: Mortality prediction using immune landscape between 2021 and 2022 in Japan” [Vaccine: X 20 (2024) 100547]","authors":"Taishi Kayano, Misaki Sasanami, Hiroshi Nishiura","doi":"10.1016/j.jvacx.2026.100865","DOIUrl":"10.1016/j.jvacx.2026.100865","url":null,"abstract":"","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"31 ","pages":"Article 100865"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148634285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of body mass index with COVID-19 risk and vaccine effectiveness in children 儿童体重指数与COVID-19风险和疫苗有效性的关系
IF 2.5
Vaccine: X Pub Date : 2026-08-01 Epub Date: 2026-07-16 DOI: 10.1016/j.jvacx.2026.100878
Karen Donceras Nadua, Janice Yu Jin Tan, Chia Yin Chong, Jiahui Li, Benjamin Ong, David Lye, Kelvin Bryan Tan, Chee Fu Yung
{"title":"Association of body mass index with COVID-19 risk and vaccine effectiveness in children","authors":"Karen Donceras Nadua,&nbsp;Janice Yu Jin Tan,&nbsp;Chia Yin Chong,&nbsp;Jiahui Li,&nbsp;Benjamin Ong,&nbsp;David Lye,&nbsp;Kelvin Bryan Tan,&nbsp;Chee Fu Yung","doi":"10.1016/j.jvacx.2026.100878","DOIUrl":"10.1016/j.jvacx.2026.100878","url":null,"abstract":"<div><h3>Background</h3><div>Real-world COVID-19 risk and COVID-19 vaccine effectiveness (VE) data in children with obesity, as measured by body mass index (BMI), remain scarce. Our objectives were to study the association of BMI and incidence of COVID-19 and related hospitalization in children and evaluate the effectiveness of the mRNA COVID-19 vaccine (COMIRNATY, Pfizer-BioNTech) two-dose primary series and booster according to BMI.</div></div><div><h3>Methods</h3><div>We conducted a population-based cohort study of children aged 5–11 years in Singapore, from 1st September 2021 until 15th August 2023, covering the delta and omicron wave periods, using data extracted from national databases. Children were categorized according to BMI: underweight (BMI &lt;5th centile), acceptable weight and overweight (BMI &gt; 90th centile). The main outcomes were incidence of COVID-19 and related hospitalization. Multivariable adjusted analysis was conducted to measure association of outcomes and BMI category. Vaccine effectiveness (VE) was calculated using incidence rate ratios.</div></div><div><h3>Results</h3><div>A total of 255,477 children (48.7% male) were included in the study, with the following distribution: underweight, <em>n</em> = 17,612 (6.9%), acceptable weight, <em>n</em> = 211,819 (82.9%), and overweight, <em>n</em> = 26,046 (10.2%). Children who were overweight were more likely to be infected compared to children with acceptable weight during delta (OR 1.26, 95% confidence interval [CI] 1.18–1.34) and omicron periods (OR 1.20, 95% CI 1.17–1.23).</div><div>Primary vaccination was effective against infection compared to unvaccinated (VE range 18–20%) and hospitalization (VE range 65–71%) in all 3 BMI categories. Booster dose improved slightly in children with overweight VE (VE 27%, 95% CI 10%–41%) but was not effective against hospitalization (VE 95% CI 0–58%). Compared to acceptable weight, cumulative COVID-19 incidence rate was higher in overweight regardless of vaccination throughout the study.</div></div><div><h3>Conclusions</h3><div>Children who were overweight had increased risk of COVID-19 throughout the delta and omicron periods. While primary series vaccination and booster dose were effective against infection in children who were overweight, despite vaccination, their incidence rate remained higher compared to vaccinated children with acceptable weight.</div></div>","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"31 ","pages":"Article 100878"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148634283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-stratified measles IgG seropositivity among measles IgM-negative children aged <15 years during the 2022–2024 outbreaks in Tanzania 坦桑尼亚2022-2024年疫情期间15岁以下麻疹igm阴性儿童的年龄分层麻疹IgG血清阳性
IF 2.5
Vaccine: X Pub Date : 2026-08-01 Epub Date: 2026-07-16 DOI: 10.1016/j.jvacx.2026.100879
Fausta S. Michael, Stephen E. Mshana, Kelvin Tenga, Gerald Misinzo, Mariam M. Mirambo
{"title":"Age-stratified measles IgG seropositivity among measles IgM-negative children aged <15 years during the 2022–2024 outbreaks in Tanzania","authors":"Fausta S. Michael,&nbsp;Stephen E. Mshana,&nbsp;Kelvin Tenga,&nbsp;Gerald Misinzo,&nbsp;Mariam M. Mirambo","doi":"10.1016/j.jvacx.2026.100879","DOIUrl":"10.1016/j.jvacx.2026.100879","url":null,"abstract":"<div><h3>Background</h3><div>Interruption of measles virus transmission requires sustained population immunity of ≥95%. This study assessed measles immunoglobulin G (IgG) seropositivity and antibody levels among measles IgM-negative children during the 2022–2024 measles outbreaks in Tanzania.</div></div><div><h3>Methods</h3><div>A total of 526 measles IgM-negative samples were analyzed using a quantitative measles IgG enzyme-linked immunosorbent assay. Seropositivity was defined as an IgG concentration ≥200 mIU/mL. Data were analyzed using STATA version 15.</div></div><div><h3>Results</h3><div>Overall measles IgG seropositivity rate was 82.7% (95% CI: 79.4–85.9). Seropositivity was similar among children who received two doses of measles-containing vaccine (MCV) (83.6%) and those who received one dose (82.1%). Seropositivity rates did not differ significantly across age groups (1–&lt;2 years: 83.7%, 2–4 years: 83.8%, 5–9 years: 78.1%, and 10–14 years: 83.3%; <em>p</em> = 0.632). However, children who received two MCV doses had significantly higher geometric mean concentrations (GMCs) of measles IgG antibodies than those who received one dose (637.8 mIU/mL [95% CI: 582.6–698.4] vs. 538.4 mIU/mL [95% CI: 506.0–571.8]; <em>p</em> = 0.002). GMCs were higher among children vaccinated at 9 months than among those vaccinated later (616.0 mIU/mL [95% CI: 570.8–665.6] vs. 539.0 mIU/mL [95% CI: 503.4–577.2]; <em>p</em> = 0.008). Samples collected during the 2022 outbreak were independently associated with IgG seronegativity (aOR = 2.56, <em>p</em> = 0.002).</div></div><div><h3>Conclusion</h3><div>IgG seropositivity remained below the ≥95% herd immunity threshold, indicating persistent immunity gaps among measles IgM negative children investigated during measles outbreaks. Strengthening timely uptake of two MCV doses is essential to interrupt measles transmission.</div></div>","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"31 ","pages":"Article 100879"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148634282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Predictors of willingness to use an HIV vaccine among gay, bisexual, and other men who have sex with men, and transgender and non-binary persons: evaluating the role of vaccine confidence, altruistic motivations, social concerns, and conspiracy beliefs” [Vaccine: X 30 (2026) 100796] “同性恋、双性恋和其他男男性行为者、跨性别者和非双性恋者愿意使用艾滋病毒疫苗的预测因素:评估疫苗信心、利他动机、社会关注和阴谋信念的作用”[疫苗:X 30(2026) 100796]的勘误。
IF 2.5
Vaccine: X Pub Date : 2026-08-01 Epub Date: 2026-06-20 DOI: 10.1016/j.jvacx.2026.100852
Amanda A. Tomaz, Thiago S. Torres, Cristina Pimenta, Silvana P. Giozza, Beatriz Grinsztejn, Valdilea G. Veloso, Paula M. Luz
{"title":"Corrigendum to “Predictors of willingness to use an HIV vaccine among gay, bisexual, and other men who have sex with men, and transgender and non-binary persons: evaluating the role of vaccine confidence, altruistic motivations, social concerns, and conspiracy beliefs” [Vaccine: X 30 (2026) 100796]","authors":"Amanda A. Tomaz,&nbsp;Thiago S. Torres,&nbsp;Cristina Pimenta,&nbsp;Silvana P. Giozza,&nbsp;Beatriz Grinsztejn,&nbsp;Valdilea G. Veloso,&nbsp;Paula M. Luz","doi":"10.1016/j.jvacx.2026.100852","DOIUrl":"10.1016/j.jvacx.2026.100852","url":null,"abstract":"","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"31 ","pages":"Article 100852"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148634284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A qualitative exploration of stakeholders' views on vaccines for the elderly in South Africa 对利益攸关方对南非老年人疫苗的看法进行定性探讨
IF 2.2
Vaccine: X Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.jvacx.2026.100779
Mncengeli Sibanda , Rosemary J. Burnett , Brian Godman , Edina Amponsah-Dacosta , Johanna C. Meyer
{"title":"A qualitative exploration of stakeholders' views on vaccines for the elderly in South Africa","authors":"Mncengeli Sibanda ,&nbsp;Rosemary J. Burnett ,&nbsp;Brian Godman ,&nbsp;Edina Amponsah-Dacosta ,&nbsp;Johanna C. Meyer","doi":"10.1016/j.jvacx.2026.100779","DOIUrl":"10.1016/j.jvacx.2026.100779","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Advancements in healthcare and living standards have led to increased life expectancy globally, including in South Africa. Despite considerable evidence from high-income countries that vaccination is a cost-effective strategy for healthy ageing, South Africa currently does not have a formal policy for vaccination of the elderly. This study explored the opinions, experiences and recommendations of South African stakeholders (experts and key opinion leaders) in the field of vaccines and healthy ageing.</div></div><div><h3>Methodology</h3><div>Online qualitative in-depth interviews with 16 stakeholders (vaccinologists, infectious disease specialists, policymakers, geriatricians and epidemiologists) were conducted. Interviews were recorded, transcribed, coded and analysed thematically using NVivo 12.0™ software.</div></div><div><h3>Results</h3><div>The overarching unanimous theme was that a national immunisation programme for the elderly (NIPE) is warranted. Aligned to this were the themes: (i) Immunisation schedule for the elderly; (ii) Health system NIPE readiness; and (iii) Strategies ensuring adequate vaccine uptake by the elderly. Participants recommended a coordinated NIPE, which could build on the successes of the Expanded Programme on Immunisation of South Africa (EPI-SA) and the recent COVID-19 vaccination programme. The NIPE should ideally be integrated into the existing primary healthcare (PHC) system programmes for the elderly. Concurrently, interventions to increase access to vaccines and reduce vaccine hesitancy among the elderly and their healthcare providers must be implemented.</div></div><div><h3>Conclusion</h3><div>A NIPE needs to be prioritised, understood, communicated, and implemented within EPI-SA and integrated into the PHC system. This should be accompanied by the requisite logistical and financial support for such a programme. The NIPE should build on the success and achievements of EPI-SA and the COVID-19 vaccination programme. Interventions that increase vaccine access and address vaccine hesitancy should also be implemented to enhance uptake by the elderly.</div></div>","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"29 ","pages":"Article 100779"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sociodemographic factors of knowledge, conspiracy beliefs, and attitudes toward Mpox among healthcare workers in Sierra Leone 塞拉利昂卫生保健工作者对麻疹的知识、阴谋信念和态度的社会人口因素
IF 2.2
Vaccine: X Pub Date : 2026-03-01 Epub Date: 2026-02-22 DOI: 10.1016/j.jvacx.2026.100799
Augustus Osborne , Alhaji Mustapha Abu , Ahmed Vandy
{"title":"Sociodemographic factors of knowledge, conspiracy beliefs, and attitudes toward Mpox among healthcare workers in Sierra Leone","authors":"Augustus Osborne ,&nbsp;Alhaji Mustapha Abu ,&nbsp;Ahmed Vandy","doi":"10.1016/j.jvacx.2026.100799","DOIUrl":"10.1016/j.jvacx.2026.100799","url":null,"abstract":"<div><h3>Background</h3><div>Mpox, a re-emerging zoonotic disease, poses a global health threat. In Sierra Leone, healthcare workers (HCWs) are central to outbreak response, yet little is known about their knowledge, conspiracy beliefs, and attitudes. This study assessed these factors and identified associated sociodemographic characteristics.</div></div><div><h3>Methods</h3><div>This cross-sectional study recruited 318 HCWs from three hospitals in Freetown using stratified random sampling. Eligible participants had at least one year of professional experience; those on leave or unwilling to participate were excluded. Data was collected using a researcher-developed questionnaire. Multivariable logistic regression identified factors, while correlation and linear regression examined interrelationships, with significance set at <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>The mean knowledge score was 65.8% (±23.7), with 53.8% showing good knowledge. Urban residence (AOR: 5.70, 95% CI: 3.01–10.80) and older age (AOR: 8.92, 95% CI: 1.76–45.15) predicted better knowledge, while clinical staff scored lower (AOR: 0.06, 95% CI: 0.02–0.15). Conspiracy beliefs were high in 44.7% of HCWs, with females more susceptible (AOR: 2.41, 95% CI: 1.31–4.43), while higher education was protective (AOR: 0.32, 95% CI: 0.16–0.63). Attitudes were polarized (49.7% positive, 50.3% negative), with good knowledge (AOR: 3.90, 95% CI: 2.01–7.54) and urban residence (AOR: 2.13, 95% CI: 1.24–3.67) predicting positive attitudes. Knowledge and attitudes were positively correlated (<em>r</em> = 0.323, <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Moderate knowledge, widespread conspiracy beliefs, and divided attitudes among HCWs underscore the need for targeted training and communication strategies. Addressing misinformation and strengthening knowledge, particularly among rural and clinical staff, are essential for Mpox preparedness in resource-limited settings.</div></div>","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"29 ","pages":"Article 100799"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147420334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying factors associated with acceptance of the fourth COVID-19 vaccine dose: A multicentre cross-sectional study in Indonesia 确定与接受第四剂COVID-19疫苗相关的因素:印度尼西亚的一项多中心横断面研究
IF 2.2
Vaccine: X Pub Date : 2026-03-01 Epub Date: 2026-01-16 DOI: 10.1016/j.jvacx.2026.100784
Muh. Akbar Bahar , Abd. Rafik Mohi , Ikhwan Yuda Kusuma , Dezső Csupor , Muh. Nasrum Massi
{"title":"Identifying factors associated with acceptance of the fourth COVID-19 vaccine dose: A multicentre cross-sectional study in Indonesia","authors":"Muh. Akbar Bahar ,&nbsp;Abd. Rafik Mohi ,&nbsp;Ikhwan Yuda Kusuma ,&nbsp;Dezső Csupor ,&nbsp;Muh. Nasrum Massi","doi":"10.1016/j.jvacx.2026.100784","DOIUrl":"10.1016/j.jvacx.2026.100784","url":null,"abstract":"<div><h3>Background</h3><div>Although the World Health Organization declared the end of COVID-19 as a global health emergency in May 2023, COVID-19 remains a public health concern due to continued transmission, variants, and waning immunity. However, the number of individuals who have received a complete series of COVID-19 vaccinations in developing countries, such as Indonesia, is still limited.</div></div><div><h3>Objective</h3><div>This study aimed to explore the factors influencing the acceptance of the fourth dose of the COVID-19 vaccine in Indonesia.</div></div><div><h3>Methods</h3><div>A multicentre cross-sectional study using an online questionnaire was conducted from June to September 2023 among the Indonesian population aged 18 years and older. The validated self-administered questionnaire consists of three parts: sociodemographic variables, clinical history, and domains of the Health Belief Model (perceived severity, perceived susceptibility, perceived clinical barriers, perceived barriers to access to booster vaccination and perceived benefits of booster vaccine). Multivariate logistic regression was employed to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for independent variables associated with acceptance of the fourth dose of the COVID-19 vaccine.</div></div><div><h3>Results</h3><div>Of 1850 eligible participants, only 11% had received the fourth dose of the COVID-19 vaccine. The independent determinants of the acceptance of the fourth dose of the COVID-19 vaccine were as follows: age groups 26–35 years (OR: 1.73, 95%CI: 1.00–3.01), 36–45 years (OR: 2.65, 95%CI: 1.35–5.21), and over 45 years (OR: 3.68, 95%CI: 2.05–6.63); working as a healthcare worker (OR: 2.03, 95%CI: 1.11–3.69); having a chronic disease (OR: 1.71, 95%CI: 1.07–2.73); history of COVID-19 infection (OR: 1.64, 95%CI: 1.12–2.41); perceived susceptibility to COVID-19 (OR: 1.31, 95%CI: 1.09–1.57); and perceived benefits of the booster vaccine (OR: 1.27, 95%CI: 1.04–1.56).</div></div><div><h3>Conclusion</h3><div>The acceptance of the fourth COVID-19 vaccine booster in Indonesia remained low, despite substantial evidence demonstrating its effectiveness and safety, particularly in protecting vulnerable populations. Vaccine coverage could be improved by campaigns based on key determinants of acceptance such as age, chronic disease, COVID-19 infection history and perceptions of vulnerability to infection and benefits of the vaccine.</div></div>","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"29 ","pages":"Article 100784"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of religious affiliation and political news on parental vaccination intent during COVID-19 pandemic COVID-19大流行期间宗教信仰和政治新闻对父母疫苗接种意向的影响
IF 2.2
Vaccine: X Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.jvacx.2026.100781
Jake Stevens, Kallysta Strong, Ella Madsen, Jeffrey Glenn, Erik J. Nelson
{"title":"Influence of religious affiliation and political news on parental vaccination intent during COVID-19 pandemic","authors":"Jake Stevens,&nbsp;Kallysta Strong,&nbsp;Ella Madsen,&nbsp;Jeffrey Glenn,&nbsp;Erik J. Nelson","doi":"10.1016/j.jvacx.2026.100781","DOIUrl":"10.1016/j.jvacx.2026.100781","url":null,"abstract":"<div><h3>Background</h3><div>In May 2021, COVID-19 vaccines became available for adolescents aged 12–15. However, safety concerns, misinformation, and politicization surrounding the vaccine left some parents hesitant to vaccinate their children. This study analyzes how media sources and religious affiliation were associated with parental COVID-19 vaccination intent.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional analysis of 5552 parents in the May 2021 COVID-19 Rapid Research Response Survey of the Adolescent Brain Cognitive Development (ABCD) study, which collected data on parental intention to vaccinate their children against COVID-19 just before the FDA approved the first vaccine for children aged 12–15. Parental vaccination intent was analyzed by media sources, religious affiliation, and other sociodemographic factors. We also fit a log-binomial regression model to examine the impact of media sources and religious affiliation on parental vaccination intent, controlling for sociodemographic factors.</div></div><div><h3>Results</h3><div>We found that, compared to parents consuming balanced media sources, parents consuming right-leaning media sources were less likely to plan to vaccinate their children [PR = 0.53 (0.47, 0.6)], while parents consuming left-leaning media sources were not significantly different from parents consuming balanced media [PR = 1.06 (0.99, 1.12)]. We also found differences in vaccination intent by religious affiliation. Compared to Christian parents, Agnostic/Atheist parents were more likely to plan to vaccinate their children [PR = 1.41 (1.35, 1.47)], as were Jewish parents [PR = 1.32 (1.22, 1.43)], and parents with no religious affiliation [(PR = 1.18 (1.14, 1.23)].</div></div><div><h3>Conclusions</h3><div>Our study highlights the multifaceted factors influencing vaccine hesitancy among parents of adolescents during the COVID-19 pandemic. To create effective public health strategies for future outbreaks, it is crucial to better understand the complex interplay of religious affiliation and media bias with vaccine hesitancy.</div></div>","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"29 ","pages":"Article 100781"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145980700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding divergent parental decisions: Declining pertussis vaccination during pregnancy while accepting infant immunisation - A qualitative study. 理解不同的父母的决定:减少百日咳疫苗接种在怀孕期间,同时接受婴儿免疫-一项定性研究。
IF 2.2
Vaccine: X Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI: 10.1016/j.jvacx.2026.100800
Daniël C.M. Huijten , Saskia den Ambtman , Liesse M.L. Vanderhoven , Veja Widdershoven , Christian J.P.A. Hoebe , Rianne P. Reijs
{"title":"Understanding divergent parental decisions: Declining pertussis vaccination during pregnancy while accepting infant immunisation - A qualitative study.","authors":"Daniël C.M. Huijten ,&nbsp;Saskia den Ambtman ,&nbsp;Liesse M.L. Vanderhoven ,&nbsp;Veja Widdershoven ,&nbsp;Christian J.P.A. Hoebe ,&nbsp;Rianne P. Reijs","doi":"10.1016/j.jvacx.2026.100800","DOIUrl":"10.1016/j.jvacx.2026.100800","url":null,"abstract":"<div><h3>Background</h3><div>Pertussis vaccination during pregnancy (VdP) is around 90% effective in protecting infants against pertussis. Passive immunisation protects infants until they are old enough to receive active immunisation themselves. Over a quarter of Dutch infants participating in the National Immunisation Program have mothers who did not receive pertussis VdP. This study aimed to identify factors related to vaccination care that influenced mothers' decision not to receive the pertussis VdP, while accepting a pertussis vaccination for their infants.</div></div><div><h3>Methods</h3><div>Semi-structured in-depth interviews were conducted with Dutch mothers, within six months postpartum, across four regions in the Netherlands: The Hague, Utrecht, and southern parts of the Dutch provinces Gelderland and Limburg. Interviews were analysed with the use of the Thematic Codebook Analysis method.</div></div><div><h3>Results</h3><div>A total of 22 participants were interviewed. The participants were diverse in age (range: 23–41) and thirteen were of Western-European origin. All participants indicated that there was not one specific reason for rejecting pertussis VdP yet accepting infant vaccination against pertussis. Their decision-making process was complex, influenced by prior experiences and pre-established views, outcome expectations, information service, trust in vaccinations and professionals, decision-making abilities, and organisational determinants.</div></div><div><h3>Conclusion</h3><div>Both decisions to decline the pertussis VdP and to accept infant pertussis vaccination take place within a dynamic societal context. Open conversations between pregnant women and healthcare professionals about VdP and infant vaccinations are essential to support informed decision-making. Understanding this process can help healthcare organisations tailor and personalise vaccination services, moving away from standardised procedures.</div></div>","PeriodicalId":43021,"journal":{"name":"Vaccine: X","volume":"29 ","pages":"Article 100800"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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