{"title":"Leucocytic Response In Pigs Experimentally Infected With Trypanosoma brucei and Subsequently Treated With Diffluoromethylornithine (DFMO) alone and in Combination with Diminazene Aceturate","authors":"G. Jibike, S. Anika","doi":"10.4314/TV.V21I4.4542","DOIUrl":"https://doi.org/10.4314/TV.V21I4.4542","url":null,"abstract":"The effect of dl-%- Diffluoromethylornithine (DFMO) alone and its combination with Diminazene aceturate (Berenil®) treatments on the leucocytic response of T.b. brucei infected pigs was investigated. Weaning pigs were experimentally infected with T. b. brucei and monitored pre and post treatment with the test drugs for parasitaemia and leucogramic changes. The infection caused overall increases in leucocyte numbers which remained high even after treatment. The leucocytosis was characterized by lymphocytosis which did not normalize with treatment, neutropaenia which rose to pre-infection level with treatments, eosinophilia and monocytosis which slowly returned to pre-infection values following treatments. It is concluded that pigs's response to T.b. bruce i infections may include a lymphocyte dominated leucocytosis which is partially sensitive to DFMO or its combination with Berenil® treatments. Key Words: Trypanosoma brucei, pigs, diffluoromethylornithine, diminazene aceturate. \u0000Trop. Vet. Vol. 21: (4) 192-199 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117251567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nafis Sadiq, J. Adejinmi, O. Adedokun, S. Fashanu, A. Alimi, Yt Sofunmade
{"title":"Ectoparasites and Haemoparasites of Indigenous Chicken ( Gallus domesticus ) In Ibadan And Environs","authors":"Nafis Sadiq, J. Adejinmi, O. Adedokun, S. Fashanu, A. Alimi, Yt Sofunmade","doi":"10.4314/TV.V21I4.4541","DOIUrl":"https://doi.org/10.4314/TV.V21I4.4541","url":null,"abstract":"This research undertook the study of ectoparasites and haemoparasites found on and in the body of indigenous chicken ( Gallus domesticus ). Six hundred and nineteen ectoparasites were collected from 375 chicken from 28 households in and around Ibadan city between February and November, 1999. Of these, 455 (72.72%) were lice, among which 253 (40.12%) were Menopon gallinae , 53 (8.4%) were Columbicola columbae , 48 (7.75%) were Goniocotes hologaster , 33 (5.33%) were Goniodes gigas , 31 (5%) were Chelopistes meleagridis , 23 (3.7%) were Liperus caponis and 15 (2.42%) were Cuclotogaster heterographus . One hundred and twenty one (19.55%) were identified as the soft tick Argas persicus . Fourty three (6.94%) mites, identified as Dermanyssus gallina e were also found. Giemsa stained smears from 150 uncoagulated chicken blood samples examined at x 1,000 magnification, revealed presence of Plasmodium species (spp.) in 48 (32%) of the samples. Leucocytozoon spp accounted for 30 (20%), while Haemoproteus spp was identified in two (1.3%) of the samples. Mixed infection with Plasmodium spp and Leucocytozoon spp were identified in 14 (9.33%), while Leucocytozoon spp and Haemoproteus spp were identified in four (2.67%) of the blood samples. Six (4%) of the blood samples have the three haemoparasites. The need to control these ectoparasites was stressed. Key Words: Ectoparasitism, haemoparasitism, Gallus domesticus. \u0000Trop. Vet. Vol. 21: (4) 187-191 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133473033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differences in the Tropism and Nitric Oxide Production by Goat Brain Cells Infected with Caprine Arthritis Encephalitis Virus","authors":"I. Adebayo, O. Adeyemo","doi":"10.4314/TV.V21I4.4543","DOIUrl":"https://doi.org/10.4314/TV.V21I4.4543","url":null,"abstract":"Different types of brain cells prepared from goat-kid cerebrum explant cultures were infected by direct application of Caprine Arthritis Encephalitis Virus (CAEV). Predominantly, cells of the monocyte-macrophage lineage were specifically infected by the virus as proviral DNA was detected in infected cultures by amplification of a 414 base-pair (bp) fragment of the viral gag-gene by Reverse Transcription-Polymerase Chain Reaction (RT-PCR). Nitric oxide (NO) production by infected brain cells under different treatment groups was quantified by photometric methods. Infected enriched microglia cells produced more NO than any other group of cells cultured from the goat brain cerebrum. The present study shows that microglia are targets cells infected by the CAE virus in the brain of goats. It is believed that this finding will assist in devising immuno-prophylactic and immuno-therapeutic measures to be adopted in the management of neurological dysfunctions resulting from retroviral infections. It is also possible that the present observation on the tropism of the virus with the attendant NO production may have important implications in the pathogenesis of retroviral and other viral infections of man and animals. Key Words: CAEV, RT-PCR, gag gene, microglia cells. \u0000Trop. Vet. Vol. 21: (3) 200-206 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133701144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of high oral magnesium chloride supplementation on the pathogenicity of Trypanosoma brucei brucei and T. congolense infections in rats","authors":"T. Egbe-Nwiyi, S. Nwaosu, Rd Tsuya","doi":"10.4314/TV.V21I3.4537","DOIUrl":"https://doi.org/10.4314/TV.V21I3.4537","url":null,"abstract":"Eighty healthy adult albino rats of both sex weighing 200-240 grams were used to assess the effect of high oral Magnesium chloride (100mg/kg body weight) supplementation on the pathogenicity of T. b. brucei (Basa strain) or T, congolense (Gboko strain) infections. Two studies were carried out and the rats were divided into 4 groups of 10 rats each (per study) namely; Group A (uninfected, unsupplemented control), Group B (uninfected and supplemented with Magnesium chloride), Group C (T.b. brucei or T. congolense infected, 1x10 6 trypanosomes and supplemented), Group D (T.b. brucei or T, congolense infected, 1x10 6 trypanosomes and unsupplemented). Each rat in groups B and C received approximately 0.2ml of MgCl2 intragastrically daily for 10 days before and during the course of the infection. The prepatent period and survival times were shorter (P \u0000Key words: Magnesium chloride; Supplementation; Trypanosomes; Pathogenicity; Rats. \u0000Trop. Vet. Vol. 21: (3) 152-159 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134479210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observation on the age at initial infection of Zebu Calves by Toxocara vitulorum in Northern Nigeria","authors":"A. Sackey, J. George, M. Sale","doi":"10.4314/TV.V21I3.4531","DOIUrl":"https://doi.org/10.4314/TV.V21I3.4531","url":null,"abstract":"A study was carried out to determine the mode of infection of neonatal zebu calves by Toxocara vitulorum in Northern Nigeria under both the extensively nomadic and the semi-intensively Institutional or Private Managements. Of the 90 calves from the 12 nomadic and 70 calves from the 8 Institutional/Private herds sampled, 20 and 10 respectively were positive for Toxocara (Neoascaris) vitulorum eggs in their faeces by the age of one week. This is a strong indication of the early infection of zebu calves by T. vitulorum, in Northern Nigeria as reported for calves of similar ages in other countries. This early infections could have been through intra-uterine route or postnatally via colostrum. Some of the calves voided mature stages of the helminth in their faeces between the ages of 7 and 8 weeks, which might be suggestive of either prenatal (intra-uterine) or postnatal (intra-mammary) modes of infections. Also, an infection rate among the calves of 91.1% for the nomadic and 61.4% for the Institutional/Private farms were observed in this study. The implications of these findings for the success of the cattle industry in Nigeria are discussed. \u0000Key Words: Toxocara vitulorum, neonatal zebu-calves; Initial age of infection. \u0000Trop. Vet. Vol. 21: (3) 124-128 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125008088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of antibodies to Toxoplasma gondii in four breeds of cattle at Ibadan, Nigeria","authors":"R. Joshua, K. Akinwumi","doi":"10.4314/TV.V21I3.4533","DOIUrl":"https://doi.org/10.4314/TV.V21I3.4533","url":null,"abstract":"Five hundred, and eighty six serum samples collected from four indigenous breeds of cattle, slaughtered at the Ibadan Municipal abattoir, were assayed for Toxoplasma antibodies by the latex agglutination technique. Ninety-nine (16.9%) of the samples were found infected at an antibody titre of 1/64. The distribution of antibodies titre to Toxoplasma gondii varied in the different breeds of cattle investigated. The highest sero-prevalence of 20.9% was detected in the White Fulani breed while the least, 6.3% was detected in the N'Dama breed. Antibodies to toxoplasma detected in other breeds were Sokoto gudali 14.7% and Red Bororo 11.7%. Neither overt clinical signs nor breed predisposition was observed in the samples investigated. Sero-epidemiological data are discussed in relation to toxoplasmosis morbidity in cattle. \u0000Key Words: Prevalence, Toxoplasma, antibody, cattle \u0000Trop. Vet. Vol. 21: (3) 134-137 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132176232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bovine Dermatophilosis in Borno State: prevalence, cultural isolation and antibiotic sensitivity pattern","authors":"B. A. Dikwa, L. Zaria","doi":"10.4314/TV.V21I3.4536","DOIUrl":"https://doi.org/10.4314/TV.V21I3.4536","url":null,"abstract":"One thousand, one hundred and ninety seven cattle were examined bacteriologically for the presence of Dermatophilosis. The result of the investigation revealed a prevalence rate of 4.5%. Bacteriological examination of the scabs and crust samples of affected cattle showed considerable variation in the cultural appearance of the various strains. Cultural comparison showed that all isolates grew at 37oC in CO2 atmosphere with differences in haemolysis pattern on bovine and ovine blood agar. Biochemical reactions showed that all strains were catalase positive and actively positive for the fermentation of glucose while most isolates fermented fructose, maltose and mannitol. Few isolates fermented xylose and sucrose and non-fermented lactose and sorbitol within 24 hours when incubated anaerobically at 37oC. Antibiotic sensitivity pattern of the isolates indicated that all strains examined were susceptible to nitrofurantoin, gentamycin, kanamycin, co-trimoxazole and tetracycline with few isolates being susceptible to colistin sulphate and ampicillin. Meanwhile all isolates were resistant to sulphafurazole. Investigations revealed that bovine dematophilosis is prevalent in Borno State. A review of present control measures is recommended. \u0000Key words: Bovine dermatophilosis, antibiotics, Borno State, Nigeria. \u0000Trop. Vet. Vol. 21: (3) 146-151 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124548445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence, abundance and intensity of Clinostomum tilapiae on cultured Oreochromis niloticus","authors":"A. Adeyemo, S. Agbede, V. Taiwo, O. Adedeji","doi":"10.4314/TV.V21I3.4532","DOIUrl":"https://doi.org/10.4314/TV.V21I3.4532","url":null,"abstract":"Clinostomum tilapiae infestation in cultured Oreochromis niloticus in fish farms within Oyo State, Nigeria is highly significant and the prevalence is normally distributed. The abundance and intensity of the parasite on the skin and within viscera of cultured O. niloticus was closely correlated while intensity was independent of prevalence at 0.05 significance level. C. tilapiae hitherto associated with wild fish species is now well recognized in cultural systems and may pose both economic and public health risks in these areas. \u0000Key Words: Prevalence, abundance, intensity, Clinostomum tilapiae, Oreochromis niloticus. \u0000Trop. Vet. Vol. 21: (3) 129-133 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133695643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effects Of Feeding Processed Cassava Meals In Growing Pigs","authors":"P. Olubunmi, T. Adenowo, O. Olagbaju","doi":"10.4314/TV.V21I3.4538","DOIUrl":"https://doi.org/10.4314/TV.V21I3.4538","url":null,"abstract":"The effects of feeding processed cassava meals in growing pigs were investigated. The average daily weight gain of control animals (40% maize was 0.34+0.06kg those of animals on processed cassava meals were 0.38+0.04kg, 0.40+0.03kg and 0.39+0.06kg for diets 2, 3 and 4 respectively. The packed cell volume of the blood of the experimental animal showed that the control diet had higher values than the other diets. Various degrees of histological lesions were observed in the livers of the experimental animals on the different cassava meals. The most pronounced lesions were noticed in animals fed with 40% sun-dried cassava meals (SDCM). Tribecular fibrosis and cellular infiltration of the portal spaces, kidney lesions including prominent glomerulonephritis were noticed in various degrees which was most prominent in animals fed on sun-dried cassava meal. Various degree of disruption of epithelial architecture of the small intestine were observed in the animals placed on the cassava-based diets; the most pronounced lesions were observed in animals fed on sun-dried cassava meal. These findings suggests that prolonged feeding of sun-dried cassava at high levels in the diet of growing pigs may result in histopathological lesions in the livers, kidneys and the small intestine of growing pigs. \u0000Key Words: Histopathology, Growing pigs, cassava meals. \u0000Trop. Vet. Vol. 21: (3) 160-167 (2003)","PeriodicalId":428776,"journal":{"name":"Tropical veterinarian","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131331197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}