Case Reports in Immunology最新文献_第9页

Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis. 大麻对危及生命的特发性复发性血管性水肿的反应。

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-07-16 DOI: 10.1155/2015/780824

Amit Frenkel, Aviel Roy-Shapira, Brotfain Evgeni, Koyfman Leonid, Abraham Borer, Moti Klein

{"title":"Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis.","authors":"Amit Frenkel, Aviel Roy-Shapira, Brotfain Evgeni, Koyfman Leonid, Abraham Borer, Moti Klein","doi":"10.1155/2015/780824","DOIUrl":"https://doi.org/10.1155/2015/780824","url":null,"abstract":"We present a case of a 27-year-old man with recurrent episodes of angioedema since he was 19, who responded well to treatment with medical grade cannabis. Initially, he responded to steroids and antihistamines, but several attempts to withdraw treatment resulted in recurrence. In the last few months before prescribing cannabis, the frequency and severity of the attacks worsened and included several presyncope events, associated with scrotal and neck swelling. No predisposing factors were identified, and extensive workup was negative. The patient reported that he was periodically using cannabis socially and that during these periods he was free of attacks. Recent data suggest that cannabis derivatives are involved in the control of mast cell activation. Consequently, we decided to try a course of inhaled cannabis as modulators of immune cell functions. The use of inhaled cannabis resulted in a complete response, and he has been free of symptoms for 2 years. An attempt to withhold the inhaled cannabis led to a recurrent attack within a week, and resuming cannabis maintained the remission, suggesting a cause and effect relationship. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2015 ","pages":"780824"},"PeriodicalIF":1.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/780824","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33906852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Systemic Sarcoidosis Presenting with Headache and Stroke-Like Episodes. 系统性结节病表现为头痛和卒中样发作。

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-09-29 DOI: 10.1155/2015/619867

J Campbell, R Kee, D Bhattacharya, P Flynn, M McCarron, A Fulton

{"title":"Systemic Sarcoidosis Presenting with Headache and Stroke-Like Episodes.","authors":"J Campbell, R Kee, D Bhattacharya, P Flynn, M McCarron, A Fulton","doi":"10.1155/2015/619867","DOIUrl":"https://doi.org/10.1155/2015/619867","url":null,"abstract":"Sarcoidosis is a multisystem granulomatous disorder. Neurological manifestations as a presenting symptom are relatively rare. A 26-year-old male presented with a five-week history of headache suggestive of raised intracranial pressure. He subsequently developed transient episodes of mild right-sided hemiparesis and numbness. Magnetic resonance imaging (MRI) of brain revealed widespread inflammatory white matter lesions, an ischaemic focus in the left corona radiata, and widespread microhaemorrhages consistent with a more diffuse vasculopathy. Serum angiotensin-converting enzyme (ACE) level was normal. Lumbar puncture revealed an elevated opening pressure (36 cmH2O) and inflammatory cerebrospinal fluid (CSF). Computerised tomography (CT) of chest, abdomen, and pelvis revealed widespread lymphadenopathy and biopsy of axillary lymph nodes revealed the presence of noncaseating granulomata in keeping with systemic sarcoidosis. The patient responded well to corticosteroids. This case highlights the importance of considering sarcoidosis to be a rare but potentially treatable cause of stroke in younger patients. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2015 ","pages":"619867"},"PeriodicalIF":1.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/619867","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34176657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Brain Abscess and Keratoacanthoma Suggestive of Hyper IgE Syndrome. 提示高IgE综合征的脑脓肿和角棘瘤。

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-04-28 DOI: 10.1155/2015/341898

Soheyla Alyasin, Reza Amin, Alireza Teymoori, Hamidreza Houshmand, Gholamreza Houshmand, Mohammad Bahadoram

{"title":"Brain Abscess and Keratoacanthoma Suggestive of Hyper IgE Syndrome.","authors":"Soheyla Alyasin, Reza Amin, Alireza Teymoori, Hamidreza Houshmand, Gholamreza Houshmand, Mohammad Bahadoram","doi":"10.1155/2015/341898","DOIUrl":"https://doi.org/10.1155/2015/341898","url":null,"abstract":"Hyper immunoglobulin-E (IgE) syndrome is an autosomal immune deficiency disease. It is characterized by an increase in IgE and eosinophil count with both T-cell and B-cell malfunction. Here, we report an 8-year-old boy whose disease started with an unusual skin manifestation. When 6 months old he developed generalized red, nontender nodules and pathologic report of the skin lesion was unremarkable (inflammatory). Then he developed a painless, cold abscess. At the age of 4 years, he developed a seronegative polyarticular arthritis. Another skin biopsy was taken which was in favor of Keratoacanthoma. Laboratory workup for immune deficiency showed high eosinophil count and high level of immunoglobulin-E, due to some diagnostic criteria (NIH sores: 41 in 9-year-olds), he was suggestive of hyper IgE syndrome. At the age of 8, the patient developed an abscess in the left inguinal region. While in hospital, the patient developed generalized tonic colonic convulsion and fever. Brain computed tomography scan revealed an abscess in the right frontal lobe. Subsequently magnetic resonance imaging (MRI) of the brain indicated expansion of the existing abscess to contralateral frontal lobe (left side). After evacuating the abscesses and administrating intravenous antibiotic, the patient's condition improved dramatically and fever stopped. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2015 ","pages":"341898"},"PeriodicalIF":1.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/341898","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33376379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

CVID Associated with Systemic Amyloidosis. CVID与系统性淀粉样变性有关。

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-08-04 DOI: 10.1155/2015/879179

Saliha Esenboga, Deniz Çagdas Ayvaz, Arzu Saglam Ayhan, Banu Peynircioglu, Ozden Sanal, Ilhan Tezcan

{"title":"CVID Associated with Systemic Amyloidosis.","authors":"Saliha Esenboga, Deniz Çagdas Ayvaz, Arzu Saglam Ayhan, Banu Peynircioglu, Ozden Sanal, Ilhan Tezcan","doi":"10.1155/2015/879179","DOIUrl":"https://doi.org/10.1155/2015/879179","url":null,"abstract":"Common variable immunodeficiency (CVID) is a frequent primary immune deficiency (PID), which consists of a heterogeneous group of disorders and can present with recurrent infections, chronic diarrhea, autoimmunity, chronic pulmonary and gastrointestinal diseases, and malignancy. Secondary amyloidosis is an uncommon complication of CVID. We report an unusual case of a 27-year-old male patient who presented with recurrent sinopulmonary infections, chronic diarrhea, and hypogammaglobulinemia and was diagnosed with CVID. The patient was treated with intravenous immunoglobulin (IVIg) therapy once every 21 days and daily trimethoprim-sulfamethoxazole for prophylaxis. Two years after initial diagnosis, the patient was found to have progressive decline in IgG levels (as low as 200-300 mg/dL) despite regular Ig infusions. The laboratory tests revealed massive proteinuria and his kidney biopsy showed accumulation of AA type amyloid. We believe that the delay in the diagnosis of CVID and initiation of Ig replacement therapy caused chronic inflammation due to recurrent infections in our patient and this led to an uncommon and life-threatening complication, amyloidosis. Patients with CVID require regular follow-up for the control of infections and assessment of adequacy of Ig replacement therapy. Amyloidosis should be kept in the differential diagnosis when managing patients with CVID. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2015 ","pages":"879179"},"PeriodicalIF":1.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/879179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34051008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Allergen Immunotherapy in an HIV+ Patient with Allergic Fungal Rhinosinusitis. 1例HIV+患者变应性真菌性鼻窦炎的过敏原免疫治疗。

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-04-14 DOI: 10.1155/2015/875260

Ian A Myles, Satyen Gada

引用次数: 2

Nocardia Brain Abscess and CD4(+) Lymphocytopenia in a Previously Healthy Individual. 先前健康个体的诺卡菌脑脓肿和CD4(+)淋巴细胞减少症。

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Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-09-16 DOI: 10.1155/2015/374956

Norair Adjamian, Adeline Kikam, Kathryn Ruda Wessell, Jason Casselman, Erin Toller-Artis, Olapeju Olasokan, Robert W Hostoffer

引用次数: 7

Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? 一抗缺乏孕妇血清IgG水平是否影响新生儿IgG水平?

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-08-27 DOI: 10.1155/2015/286380

Vasantha Nagendran, Noel Emmanuel, Amolak S Bansal

引用次数: 6

A Case Report of Allergic Contact Dermatitis due to Mandragora Radix. 甘露菊致过敏性接触性皮炎1例。

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-08-04 DOI: 10.1155/2015/591438

Sevim Baysak, Müzeyyen Gönül, Damla Atacan, Can Ergin

引用次数: 2

Immunodeficiency in a Child with Rapadilino Syndrome: A Case Report and Review of the Literature. 儿童Rapadilino综合征的免疫缺陷:1例报告及文献回顾。

IF 1

Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-05-06 DOI: 10.1155/2015/137368

M M G Vollebregt, A Malfroot, M De Raedemaecker, M van der Burg, J E van der Werff Ten Bosch

引用次数: 3

Combined treatment with antiviral therapy and rituximab in patients with mixed cryoglobulinemia: review of the literature and report of a case using direct antiviral agents-based antihepatitis C virus therapy. 抗病毒治疗和利妥昔单抗联合治疗混合冷球蛋白血症患者:文献综述和使用直接抗病毒药物治疗丙型肝炎的病例报告

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Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-03-01 DOI: 10.1155/2015/816424

Teresa Urraro, Laura Gragnani, Alessia Piluso, Alessio Fabbrizzi, Monica Monti, Elisa Fognani, Barbara Boldrini, Jessica Ranieri, Anna Linda Zignego

引用次数: 31