Case Reports in Immunology最新文献_第10页

Fever of unknown origin: an unusual presentation of kikuchi-fujimoto disease. 不明原因发热:菊chi-fujimoto病的不寻常表现。

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Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-03-22 DOI: 10.1155/2015/314217

Piyush Ranjan, Manish Soneja, Nellai Krishnan Subramonian, Vivek Kumar, Shuvadeep Ganguly, Tarun Kumar, Geetika Singh

引用次数: 4

Hereditary Angioedema and Gastrointestinal Complications: An Extensive Review of the Literature. 遗传性血管性水肿和胃肠道并发症:广泛的文献综述。

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Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-08-03 DOI: 10.1155/2015/925861

Napoleon Patel, Lisbet D Suarez, Sakshi Kapur, Leonard Bielory

{"title":"Hereditary Angioedema and Gastrointestinal Complications: An Extensive Review of the Literature.","authors":"Napoleon Patel, Lisbet D Suarez, Sakshi Kapur, Leonard Bielory","doi":"10.1155/2015/925861","DOIUrl":"https://doi.org/10.1155/2015/925861","url":null,"abstract":"Hereditary Angioedema (HAE) is a rare autosomal dominant (AD) disease characterized by deficient (type 1) or nonfunctional (type 2) C1 inhibitor protein. The disorder is associated with episodes of angioedema of the face, larynx, lips, abdomen, or extremities. The angioedema is caused by the activation of the kallikrein-kinin system that leads to the release of vasoactive peptides, followed by edema, which in severe cases can be life threatening. The disease is usually not diagnosed until late adolescence and patients tend to have frequent episodes that can be severely impairing and have a high incidence of morbidity. Gastrointestinal involvement represents up to 80% of clinical presentations that are commonly confused with other gastrointestinal disorders such as appendicitis, cholecystitis, pancreatitis, and ischemic bower. We present a case of an HAE attack presenting as colonic intussusception managed conservatively with a C1 esterase inhibitor. Very few cases have been reported in the literature of HAE presentation in this manner, and there are no reports of any nonsurgical management of these cases. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2015 ","pages":"925861"},"PeriodicalIF":1.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/925861","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33977951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Successful desensitization of a patient with rituximab hypersensitivity. 1例利妥昔单抗过敏患者成功脱敏。

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Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-01-20 DOI: 10.1155/2015/524507

Pinar Ataca, Erden Atilla, Resat Kendir, Sevim Bavbek, Muhit Ozcan

引用次数: 14

Behcet's Disease with Intracardiac Thrombus Presenting with Fever of Unknown Etiology. 白塞病合并心内血栓以不明原因的发热为表现。

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Case Reports in Immunology Pub Date : 2015-01-01 Epub Date: 2015-09-03 DOI: 10.1155/2015/149359

Sajal Ajmani, Durga Prasanna Misra, Deep Chandh Raja, Namita Mohindra, Vikas Agarwal

引用次数: 1

Infectious and noninfectious granulomatosis in patient with multiple sclerosis: diagnostic dilemmas and followup. 多发性硬化症患者感染性和非感染性肉芽肿:诊断困境和随访。

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Case Reports in Immunology Pub Date : 2014-01-01 Epub Date: 2014-02-17 DOI: 10.1155/2014/876525

Jelena Paovic, Predrag Paovic, Vojislav Sredovic

引用次数: 0

Recurrent Skin and Lung Infections in Autosomal Dominant Hyper IgE Syndrome with Transactivation Domain STAT3 Mutation. 常染色体显性高IgE综合征伴转激活域STAT3突变的复发性皮肤和肺部感染。

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Case Reports in Immunology Pub Date : 2014-01-01 Epub Date: 2014-03-05 DOI: 10.1155/2014/136752

Chad J Cooper, Sarmad Said, German T Hernandez

{"title":"Recurrent Skin and Lung Infections in Autosomal Dominant Hyper IgE Syndrome with Transactivation Domain STAT3 Mutation.","authors":"Chad J Cooper, Sarmad Said, German T Hernandez","doi":"10.1155/2014/136752","DOIUrl":"https://doi.org/10.1155/2014/136752","url":null,"abstract":"Background. Hyper IgE is a rare systemic disease characterized by the clinical triad of high serum levels of IgE (>2000 IU/mL), eczema, and recurrent staphylococcal skin and lung infections. The presentation of hyper IgE syndrome is highly variable, which makes it easy to confuse the diagnosis with that of severe atopy or other rare immunodeficiency disorders. Case Report. A 23-year-old Hispanic presented with history of frequent respiratory and gastrointestinal infections as a child and multiple episodes of skin and lung infections (abscess) with Staphylococcus aureus throughout his adult life. He had multiple eczematous lesions and folliculitis over his entire body, oral/esophageal candidiasis, and retention of his primary teeth. The IgE was elevated (>5000 IU/mL). Genetic mutation analysis revealed a mutation affecting the transactivation domain of the STAT3 gene. Conclusion. The hallmark of hyper IgE syndrome is serum IgE of >2000 IU/mL. Hyper IgE syndrome is a genetic disorder that is either autosomal dominant or recessive. A definite diagnosis can be made with genetic mutation analysis, and in this case, it revealed a very rare finding of the transactivation domain STAT3 mutation. Hyper IgE syndrome is a challenge for clinicians in establishing a diagnosis in suspected cases. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2014 ","pages":"136752"},"PeriodicalIF":1.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/136752","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32800659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Systemic lupus erythematosus with hepatosplenic granuloma: a rare case. 系统性红斑狼疮合并肝脾肉芽肿1例。

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Case Reports in Immunology Pub Date : 2014-01-01 Epub Date: 2014-11-20 DOI: 10.1155/2014/737453

Anju Bharti, Lalit Prashant Meena

引用次数: 4

Lepra reaction with lucio phenomenon mimicking cutaneous vasculitis. Lepra反应伴lucio现象，模拟皮肤血管炎。

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Case Reports in Immunology Pub Date : 2014-01-01 Epub Date: 2014-12-17 DOI: 10.1155/2014/641989

Durga Prasanna Misra, Jyoti Ranjan Parida, Abhra Chandra Chowdhury, Krushna Chandra Pani, Niraj Kumari, Narendra Krishnani, Vikas Agarwal

引用次数: 18

Periodic Fever and Neutrophilic Dermatosis: Is It Sweet's Syndrome? 周期性发热与中性粒细胞性皮肤病:是斯威特综合征吗?

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Case Reports in Immunology Pub Date : 2014-01-01 Epub Date: 2014-12-04 DOI: 10.1155/2014/320920

Raheleh Assari, Vahid Ziaee, Nima Parvaneh, Mohammad-Hassan Moradinejad

{"title":"Periodic Fever and Neutrophilic Dermatosis: Is It Sweet's Syndrome?","authors":"Raheleh Assari, Vahid Ziaee, Nima Parvaneh, Mohammad-Hassan Moradinejad","doi":"10.1155/2014/320920","DOIUrl":"https://doi.org/10.1155/2014/320920","url":null,"abstract":"A 7-year-old boy with high grade fever (39°C) and warm, erythematous, and indurated plaque above the left knee was referred. According to the previous records of this patient, these indurated plaques had been changed toward abscesses formation and then spontaneous drainage had occurred after about 6 to 7 days, and finally these lesions healed with scars. In multiple previous admissions, high grade fever, leukocytosis, and a noticeable increase in erythrocyte sedimentation rate and C-reactive protein were noted. After that, until 7th year of age, he had shoulder, gluteal, splenic, kidney, and left thigh lesions and pneumonia. The methylprednisolone pulse (30 mg/kg) was initiated with the diagnosis of Sweet's syndrome. After about 10-14 days, almost all of the laboratory data regressed to nearly normal limits. After about 5 months, he was admitted again with tachypnea and high grade fever and leukocytosis. After infusion of one methylprednisolone pulse, the fever and tachypnea resolved rapidly in about 24 hours. In this admission, colchicine (1 mg/kg) was added to the oral prednisolone after discharge. In the periodic fever and neutrophilic dermatosis, the rheumatologist should search for sterile abscesses in other organs. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2014 ","pages":"320920"},"PeriodicalIF":1.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/320920","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32938071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Bilateral lung transplantation in a patient with humoral immune deficiency: a case report with review of the literature. 体液免疫缺陷患者的双侧肺移植一例报告并复习文献。

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Case Reports in Immunology Pub Date : 2014-01-01 Epub Date: 2014-10-15 DOI: 10.1155/2014/910215

Jocelyn R Farmer, Caroline L Sokol, Francisco A Bonilla, Mandakolathur R Murali, Richard L Kradin, Todd L Astor, Jolan E Walter

{"title":"Bilateral lung transplantation in a patient with humoral immune deficiency: a case report with review of the literature.","authors":"Jocelyn R Farmer, Caroline L Sokol, Francisco A Bonilla, Mandakolathur R Murali, Richard L Kradin, Todd L Astor, Jolan E Walter","doi":"10.1155/2014/910215","DOIUrl":"https://doi.org/10.1155/2014/910215","url":null,"abstract":"Humoral immune deficiencies have been associated with noninfectious disease complications including autoimmune cytopenias and pulmonary disease. Herein we present a patient who underwent splenectomy for autoimmune cytopenias and subsequently was diagnosed with humoral immune deficiency in the context of recurrent infections. Immunoglobulin analysis prior to initiation of intravenous immunoglobulin (IVIG) therapy was notable for low age-matched serum levels of IgA (11 mg/dL), IgG2 (14 mg/L), and IgG4 (5 mg/L) with a preserved total level of IgG. Flow cytometry was remarkable for B cell maturation arrest at the IgM+/IgD+ stage. Selective screening for known primary immune deficiency-causing genetic defects was negative. The disease course was uniquely complicated by the development of pulmonary arteriovenous malformations (AVMs), ultimately requiring bilateral lung transplantation in 2012. This is a patient with humoral immune deficiency that became apparent only after splenectomy, which argues for routine immunologic evaluation prior to vaccination and splenectomy. Lung transplantation is a rare therapeutic endpoint and to our knowledge has never before been described in a patient with humoral immune deficiency for the indication of pulmonary AVMs. ","PeriodicalId":42865,"journal":{"name":"Case Reports in Immunology","volume":"2014 ","pages":"910215"},"PeriodicalIF":1.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/910215","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32799518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3