Journal of Contemporary Medical Sciences最新文献

{"title":"Determine Biofilm Genes in Pseudomonas Aeruginosa Isolated from Clinical and Environmental Samples","authors":"Riyam Khalid Attallah AL-Mashhadani, Mohammed Fadhil AboKsour, O. Dakhil","doi":"10.22317/jcms.v10i3.1557","DOIUrl":"https://doi.org/10.22317/jcms.v10i3.1557","url":null,"abstract":"Objective: Isolates of Pseudomonas aeruginosa are an extremely adaptable bacterium that causes opportunistic diseases because of its varied metabolic pathways, genes, virulence factors, and considerable antibiotic resistance. \u0000Methods: A total of 293 samples were collected from different places: 193 samples (% 65.87) of human samples and 100 samples (% 34.13) of wastewater samples in the period between 3rd September to 15th November 2023). Bacterial isolates were identified according to microscopic, cultural, and genetic characteristics. Antibiotic susceptibility of bacterial isolates was determined against twelve of the selected antibiotics. The biofilm production was done by using phenotypic ways (Congo red agar and Microtiter plate methods) as well as genotypic ways by detection of biofilm genes (algD, pelf, and pslD genes). \u0000Results: Hundred-forty eight bacterial isolates were obtained, and sixty of these isolates were identified as Pseudomonas spp. (40.9%), twenty-six isolates of E. coli (17.9%), seventeen isolates of K. pneumoniae (11.3%), and forty-five isolates were beyond to other types of bacteria (30.1%), and out of sixty isolates of Pseudomonas spp., forty-two were identified as P. aeruginosa isolates. P. aeruginosa isolates revealed various resistance levels to antimicrobial agents gradually, ranging from 83.87% to Trimethoprim-sulfamethoxazole (SXT) to 3.22% to Aztreonam (AZT). Biofilm production by using the Congo red method showed that 27 isolates (64.28%) were positive results, while in the microtiter method, all forty-two isolates were positive (100%), the genetic detection showed that the AlgD gene was recognized in thirty-one isolates (73.8%), followed by Pelf and PslD genes in four isolates each (9.5%). \u0000Conclusion: The isolation percentage showed a high occurrence of multi-drug resistance biofilm forming Pseudomonas spp. isolates which could be a critical indicator. Methods of biofilm detection showed that the microtiter plate method has accuracy more than the Congo red method; as well AlgD gene was prevalent compared with both other genes Pelf, and PslD.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Inflammatory Markers in Patients with Fibromyalgia Syndrome in King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia: A Cross-Sectional Study","authors":"Y. Bawazir, Mohammad Mustafa, Bushra Almusally, Rola Hassan, I. Jali, Roaa Alsolaimani, Deyaa A. Mukhtar, Mohammed K. Alharazi, Ammar Assadullah Bokhari","doi":"10.22317/jcms.v10i3.1580","DOIUrl":"https://doi.org/10.22317/jcms.v10i3.1580","url":null,"abstract":"Objectives: The goal of this study was to examine various markers in patients with FMS, including the neutrophil/lymphocyte ratio (NLR),platelet/lymphocyte ratio (PLR), platelet distribution width (PDW), and mean platelet volume (MPV). \u0000Methods: This was a cross-sectional, retrospective study conducted at King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia,involving the examination of inflammatory markers, such as PDW, NLR, and MPV. The results were evaluated with IBM SPSS version 25, and a P-value of <0.05 was used to reject the null hypothesis. \u0000Results: In total, 396 participants were included in this study: 235 in the FMS group and 161 in the control group. MPV, PDW and NLR values are 10.31 ± 1.6 fL, 124.57 ± 70.0, 2.30 ± 3.2, respectively. The PDW in the control group (12.47 ± 2.5) was significantly higher than that in the FMS group (11.84 ± 2.4) (P = 0.003). Erythrocyte sedimentation rate and Vitamin D levels (P = 0.001) were significantly higher in the control group than in the FMS group, with values of 31.71 and 24.2 and 75.60 and 39.4, respectively. No significant differences were found in MPV and NLR values between the FMS and control groups. \u0000Conclusion: The findings in this study suggest that PDW and PLR are important inflammatory markers that may be beneficial in FMSdiagnosis.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Diabetes and Hyperuricemia in Zakho city – Kurdistan region of Iraq: A Retrospective Cross-Sectional Study","authors":"Brisik Gardi","doi":"10.22317/jcms.v10i3.1568","DOIUrl":"https://doi.org/10.22317/jcms.v10i3.1568","url":null,"abstract":"Objective: This retrospective cross-sectional study aimed to explore the prevalence of hyperuricemia among patients with type 2 diabetes mellitus and identify associated factors.\u0000Methods: A total of 228 adult patients diagnosed with type 2 diabetes mellitus were included in this study. Data including demographic characteristics, clinical parameters, and serum uric acid levels were collected from medical records. Patients were categorized into two groups based on uric acid levels: hyperuricemia (≥7 mg/dL for males, ≥6 mg/dL for females) and non-hyperuricemic. Descriptive statistics and unpaired t-tests were utilized for analysis.\u0000Results: A total of 228 patient were included (60.53% of them were female), according to standard guidelines hyperuricemia was defined as (≥ 7 mg/dl for male and ≤ 6 mg/dl for female) among them, 39.47% exhibited hyperuricemia. Mean uric acid level was 5.84±2.03. Significant associations were observed between uric acid levels and age (p = 0.0003), marital status (p = 0.0358), duration of diabetes (p = 0.0013), and HbA1c levels (p < 0.0001). However, other factors such as gender, smoking status, family history of diabetes, body mass index, and waist circumference did not show significant associations with uric acid levels.\u0000Conclusion: This study highlights a notable prevalence of hyperuricemia among patients with type 2 diabetes mellitus. Factors such as older age, longer duration of diabetes, and poorer glycemic control were associated with higher uric acid levels. These findings underscore the importance of monitoring and managing uric acid levels in diabetic patients to mitigate potential metabolic complications. Further prospective studies are warranted to elucidate the underlying mechanisms and clinical implications of this relationship.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Fungal and Bacterial Bioagent Formula Antagonists to Combat Fusarium Oxysporum f. sp. Lycopersici Under Greenhouse Conditions","authors":"N. Bouqellah, N. Muhanna, Said Mohamed Kamel, T. Essa, Hisham Abd Elmonim Mohamed, Sabry Shahen, H. Ketta","doi":"10.22317/jcms.v10i3.1554","DOIUrl":"https://doi.org/10.22317/jcms.v10i3.1554","url":null,"abstract":"Objective: This study aimed to test fungal and bacterial bioagents as formula antagonists of Fusarium oxysporum f. sp. lycopersici under greenhouse conditions.   \u0000  \u0000Methods: The fungal and bacterial formulations' shelf life under different temperatures as well as under growth chamber and greenhouse conditions, as well as their effects on biochemical alterations involved in the induction of plant defense against the causative pathogen were investigated. \u0000  \u0000Results: In-vitro antagonist screening of bacterial and fungal isolates on radial growth, reduction and inhibition percentages revealed that T. harzianum exhibited 45.6% of inhibition followed by B. pumilus with 36.7%. Among the fungal and bacterial bio-agents, the highest effect on disease incidence and efficiency against pathogenic fungus under greenhouse conditions was B. pumilus 27 and 69%, respectively followed by T. harzianum 33 and 62% when applied before pathogen inoculation. Under greenhouse conditions, the effects of bio-fungicides also affected defense enzymes like peroxidase and polyphenol oxidase. The shelf life of the wettable powder formulation of bio-agents under different temperature was very important factor and established that the most suitable temperature for long term storage is 25 ºC for both B. pumilus and T. harzianum. \u0000Conclusion: Target application of disease control techniques in tomato plants demonstrated the efficacy of B. pumilus and T. harzianum in reducing Fusarium wilt. These results pave the way for the development of bio-agents that can replace fungicides in agriculture, offering a practical substitute.        ","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Risk of Acute Kidney Injury in Patients Undergoing Coronary Angiography","authors":"H. Alhozali, Mohammed Qutub, Nada Mohammed Alharbi, Ghram W Awlia, Meiral I Alraddadi, Areej Algarni, Renad A Almutiry","doi":"10.22317/jcms.v10i3.1509","DOIUrl":"https://doi.org/10.22317/jcms.v10i3.1509","url":null,"abstract":"Objective: This study was conducted to estimate the risk of contrast-induced AKI (CI-AKI), among Saudi patients who underwent CA or PCI at a tertiary care hospital, to understand the incidence and the underlying contributory factors of CI-AKI.\u0000Methods: We conducted a retrospective review of patients who underwent CA or PCI from 1st January 2018 to 31st December 2020, at the King Abdulaziz University Hospital, Jeddah, Saudi Arabia.  \u0000The exclusion criteria comprised age <18 years, preexisting chronic kidney disease (stage III–V), prior renal transplantation and records with missing key clinical information. Occurrence of AKI was defined using the “Kidney Disease: Improving Global Outcomes” (KDIGO) consensus definition. Statistical Package for the Social Sciences (SPSS) software, version 21 was used for statistical analysis. The prevalence is presented as a percentage with a 95% confidence level. P-value <0.05 was considered statistically significant.\u0000Results: We reviewed 825 patient files, of which 754 met the inclusion criteria. According to the KDIGO classification, the mean overall incidence of Stage I CI-AKI in our study cohort was 8.1%, while no patients developed stage II and III AKI. The incidence of CI-AKI was 6.4% in patients <55 years of age (n=264) and 7.8% in the age group of 55-70 years. A significantly higher incidence of 13.3% was seen in patients above the age of 70 years. The increase in the incidence of CI-AKI in patients above 70 years, versus their younger counterparts was statistically significant (P = 0.075).\u0000Conclusions: Based on the results of this study and past literature, the overall incidence of CI-AKI is around ≤10%, among patients undergoing CA or PCI; which seems lower than the high risk perception among cardiologists. While CI-AKI is a known post-procedural complication of CA or PCI, the apprehension of the potential risk of CI-AKI, should not defer or obstruct the decision to perform CA or PCI for deserving and needy candidates. Exercising caution among high-risk patients, individual risk-benefit assessment and employing well-established pre and peri-procedural prevention protocols can significantly mitigate the risk of CI-AKI; even among high-risk patients.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Mediating Role of the REJ Region: PC1 and Extracellular Matrix Dynamics in ADPKD","authors":"Aljazi Abdullah Alrashidi, H. S. Sonbol","doi":"10.22317/jcms.v10i1.1508","DOIUrl":"https://doi.org/10.22317/jcms.v10i1.1508","url":null,"abstract":"Objective: This study aimed to investigate the interactions of PC1 with extracellular matrix proteins (ECM) to gain insights into its role in ADPKD onset. This exploration objective is to unravel the significance of these interactions in both the healthy development of kidneys and the underlying mechanisms of ADPKD, potentially identifying therapeutic targets. \u0000Methods: We cloned and expressed the receptor of the egg jelly (REJ) domain as a maltose-binding protein-fusion protein (PET21-MBP(TEV)-REJ). Subsequently, we utilized this construct in a pulldown assay involving HEK 293 cells. In vitro, pull-down assays were conducted to evaluate the binding of the REJ fusion to various ECM components. \u0000Results: The REJ fusion protein effectively binds to vitronectin, Fibulin-1, and actin filament-associated protein (AFAP) 1. These findings indicate that the REJ region acts as a mediator for the interaction between polycystin-1 and the ECM, shedding light on the functional role of polycystin-1 in both cell-matrix and cell-cell interactions. \u0000Conclusion: The detailed characterization of REJ-ECM interactions offers a valuable foundation for future research aimed at systematically studying the effects of disease-causing mutations within the REJ module of human PC-1.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140428976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vildagliptin Nephroprotective Effect in Rats Model with Cisplatin-Induced Nephrotoxicity","authors":"Abeer T. Watife, A. Bairam, N. H. Al-Ghuraibawi","doi":"10.22317/jcms.v10i1.1481","DOIUrl":"https://doi.org/10.22317/jcms.v10i1.1481","url":null,"abstract":"Objective: To evaluate the nephroprotective effect of vildagliptin against cisplatin-induced nephrotoxicity in rats. \u0000Methods and Materials: Twenty-eight male rats have been divided into four groups: Control (received distal water), cisplatin treated group (received single dose of cisplatin (7mg/kg) intraperitoneally (IP) on day eight), vildagliptin plus cisplatin treated group (received vildagliptin 10mg/kg/day orally for 14 days, seven days before and seven days after the dose of cisplatin on day eight), and vildagliptin treated group (received the same dose and duration of vildagliptin mentioned previously). At the end, blood samples were collected to evaluate tumor necrotic factor-α (TNF-α), caspase-3, total antioxidant capacity (TAOC), urea, and creatinine. The serum levels of these biomarkers were expressed as mean ± standard error of mean. Additionally, kidneys were fixed in formalin for histopathological examination. \u0000Result: Vildagliptin treatment significantly reduced the serum levels of TNF-α, caspase-3, urea, and creatinine as well as increased the TAOC level in rats treated with vildagliptin plus cisplatin when compared with cisplatin treated group. Histopathological examination further supported the nephroprotective effect of vildagliptin in rats with cisplatin induced nephrotoxicity.  \u0000Conclusion: Vildagliptin improved kidney function and reduced cisplatin nephrotoxicity which may highlight the nephroprotective effect of this DPP-4 inhibitor against cisplatin-induced nephrotoxicity.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting Healthier Futures: A Six-Month Program for Childhood Obesity Reduction and Lifestyle Enhancement","authors":"Sabah Mohammed, Sherzad Abdulahad Shabu","doi":"10.22317/jcms.v10i1.1462","DOIUrl":"https://doi.org/10.22317/jcms.v10i1.1462","url":null,"abstract":"Objective: This study aimed to evaluate the impact of a six-month family-based intervention and follow-up intervention on the body mass index and children's lifestyle in Erbil City among 5 to 19 years old. The intervention specifically targeted parents to the educational program and intended to reduce the Body Mass Index of children and change sedentary behavior. On the other hand, the educational program included minimizing the consumption of high-fat and carbohydrate-containing, increasing the consumption of fruits and vegetables, and soft drinks. In addition, it assessed exposure to multi-screen devices and evaluated sleep quality.\u0000Methods: Weight, height, waist circumference, and hip circumference were measured by portable stadiometer and weight-calibrated electronic scales and BMI was calculated at the baseline and after six months of intervention. The research employed various methodologies and conducted a family-based educational program through a printed booklet. The questionnaire was used at baseline and after six months of intervention, and IBM SPSS Statistics version 25 was used for data analysis, paired sample t-test and MacNemar Chi-square were used.\u0000Results: The BMI was reduced after six months of intervention. The mean difference was 0.435, however, there were no more differences for hip and waist circumference, on the other hand, the sedentary behaviour lifestyle was changed from poor daily lifestyle practice to good practice.\u0000Conclusion: The results of this research suggest that the implementation of a complete intervention produces favourable outcomes in terms of lifestyle modifications and a decrease in BMI among children who are obese or overweight. Although, daily practice was notable changed from poor daily practice to good practice.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using a Rapid, Accurate, and Cost-Effective QiaXcel Advanced Platform for Microsatellite Instability Detection in Colorectal Carcinoma in North of Iraq","authors":"Nigar A Abdalrahman, Dlnya A. Mohamad","doi":"10.22317/jcms.v10i1.1469","DOIUrl":"https://doi.org/10.22317/jcms.v10i1.1469","url":null,"abstract":"Objective: The objective of this investigation was to address the limitations of the most popular microsatellite instability (MSI) detectionmethod, which uses fluorescent capillary sequencers.\u0000Methods: Using the QiaXcel Advanced system (Qiagen, Hilden, Germany) based on capillary electrophoresis, the MSI status of 53 IraqiFormalin Fixed Paraffin Embedded (FFPE) CRC samples was examined. BAT25, BAT26, BAT40, D2S123, D5S346, D17S250, NR21, NR22, NR27,Mycl1, TPOX, and TH01 were among the panel of twelve polymorphic markers that were used.\u0000Results: Using a QiaXcel Advanced platform was successfully established to determine the MSI status. Among 53 cases of CRC, MSI wasobserved in 12 cases (22.64%) who had MSI-H.\u0000Conclusion: Due to MSI’s significance in the progression of cancer, this quick and inexpensive PCR-based technique can enhance theclinical management of CRC, which may further alter the patient’s outcome.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140429675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic Insights: Examining CNTNAP2 rs7794745 Gene Polymorphism and Its Impact on ABLLS Assessment in Middle Euphrates Children in Iraq with Autism Spectrum Disorder","authors":"Safaa R. M. AL-Safar, Haydar F. S. AL-Zubaidy, Roaa Hameed Alwaidh","doi":"10.22317/jcms.v10i1.1511","DOIUrl":"https://doi.org/10.22317/jcms.v10i1.1511","url":null,"abstract":"Objective:  examine the effect of CNTNAP2 gene polymorphism on behavioral therapy response in Iraqi children with autism spectrum disorder using ABLLS-r. \u0000Methods: In this study, 150 samples for autism spectrum disorder were obtained from AL-SIBTEIN ACADEMY, however owing to many challenges, the final number of samples was 50 patients. Polymerase Chain Reaction-Restriction refers to a technique that combines the use of polymerase chain reaction (PCR) with restriction enzymes to amplify and analyze certain DNA sequences. Fragment Length Polymorphism (PCR-RFLP) was used to genotype the CNTNAP2 gene at rs7794745. All 25 ABLLS-R repertoires and all four primary components had their dependent parameters determined by aggregating and converting the ABLLS data to a percentage. This provided us with the proportion of finished assignments from each repertoire. \u0000Results: After correlating the genotype data (AA/AT/TT) with the behavioral therapy response as indicated by ABLLS-R, we only discovered a statistically significant difference between the frequency of AA/TT genotypes in the rs7794745 variant in patients and the social interaction domain. Conversely, the remaining 24 subdomains exhibited no discernible correlation. \u0000Conclusion: This research topic could provide significant information on targeting and categorizing which skill areas need to be developed based on genetic models' influence.","PeriodicalId":42860,"journal":{"name":"Journal of Contemporary Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}