{"title":"Typhoid epidemic in Hakkari - March 2007: evaluation of affected pediatric patients.","authors":"R. Ozdemir, Emine Kayatas","doi":"10.5222/BUCHD.2012.137","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.137","url":null,"abstract":"Objective: Salmonella typhi is a food and water-borne agent of a serious human disease, and it is transmitted by faecal-oral route. In the presence of inadequate infrastructure facilities; poor sanitation and health care; outbreaks of typhoid fever via contamination of drinking water were reported. In this study; pediatric cases of typhoid fever outbreak were reviewed in Hakkari and we also emphasized that typhoid fever is still a serious health problem in East and Southeast Anatolia region. Methods: In this article children who were diagnosed and treated for typhoid fever were reviewed. Totally 118 children who were admitted to Hakkari State Hospital and a private medical center, diagnosed as typhoid fever were included during the period between 5. and 30. of March 2007. The diagnosis of typhoid fever was based on the results of Gruber Widal agglutination tests. Results: Sixty eight patients were male (57.6%) and 50 were female (42.4%). Mean age was 8.4 years (10 months-17 years). Presenting symptoms in order of decreasing frequency were fever (100%), malaise (100%), headache (74%), abdominal pain (39.8%), vomiting (29.6%), diarrhea (21.1%), cough (16.9%), and epistaxis (5%). Hepatomegaly was remarkable compared to splenomegaly in physical examination of the cases. The most common laboratory features were elevated acute phase reactants, anemia (81%), leukopenia (56%), thrombocytopenia (3.5%), and elevated transaminase levels (28%). Conclusion: Forty four patients (37.2%) were hospitalized and treated for deydration due to vomiting and poor oral intake. One patient had developed a clinical picture of subileus as a complication.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122711849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dyke-Davidoff-Masson syndrome: a case report.","authors":"Hande Turan, A. Ünalp, E. Toprak, N. Ünal","doi":"10.5222/buchd.2012.194","DOIUrl":"https://doi.org/10.5222/buchd.2012.194","url":null,"abstract":"Dyke-Davidoff-Masson Syndrome is a condition characterized by seizures, facial asymmetry, contralateral hemiplegia or hemiparesis and mental retardation. Radiological features are typical, such as unilateral loss of cerebral volume and associated compensatory bone alterations in the calvarium,ventricular asimmetry, skull vault thickening, hyperpneumatization of the frontal sinuse and mastoid cells. A 46-year-old female presented with seizures, right-sided hemiparesis, hemiatrophy of the right side of the body and mental retardation.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121472131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An uncommon cause of respiratory distress in infancy: right aortic arch anomaly.","authors":"M. Doğru, T. Giniş, I. Bostanci","doi":"10.5222/BUCHD.2012.191","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.191","url":null,"abstract":"Right aortic arch anomaly is a rare vascular pathology. It may cause respiratory and gastrointestinal tract symptoms by compressing adjacent structures. Here, we presented a case who admitted with complaints of rapid breathing, cough and wheezing in our clinic who was diagnosed as right aortic arch anomaly. Anatomical abnormalities should be considered in cases with wheezing persisting since birth which does not respond to treatment with bronchodilators.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116638467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ö. Olukman, Ş. Çalkavur, F. Kılıç, D. Okur, F. Atlihan, A. Ünalp
{"title":"A rare chronic progressive leukoencephalopathy of childhood: Two newborn cases with vanishing white matter disease","authors":"Ö. Olukman, Ş. Çalkavur, F. Kılıç, D. Okur, F. Atlihan, A. Ünalp","doi":"10.5222/BUCHD.2012.170","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.170","url":null,"abstract":"Vanishing white matter disease, which is one of the most prevalent inherited childhood leukoencephalopathies, has an extremely wide phenotypic variation. The classical phenotype is characterized by early childhood onset of chronic neurological deterioration, dominated by cerebellar ataxia. However cases with antenatal onset, severe clinical course in the neonatal period and early demise have been also defined in the literature. Almost all diagnosed newborns present with rapid neurological deterioration and unexplained coma soon after birth. Other symptoms include feeding intolerance, hypotonia, seizures, apnea and severe respiratory distress. The exact pathogenesis is not known. Cerebral magnetic resonance imaging and spectroscopy are diagnostic. Differential diagnosis is difficult in the neonatal period and the disease may be misdiagnosed as hypoxic ischemic encephalopathy, congenital infections and inborn errors of metabolism. Here we present two premature infants with unexplained comatose state and severe neurological symptoms whose cerebral imaging studies were indicative of rarefaction and cystic degeneration of the cerebral white matter, and particularly emphasize on the differential diagnosis and the importance of cerebral imaging studies in the newborn period.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128984517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Kılıç, Ş. Çalkavur, Ö. Olukman, Gulten Ercan, Y. Oruç, Dilek Ozkok, D. Okur, Gamze Gülfidan, I. Devrim, F. Atlihan
{"title":"Management of vancomycin-resistant enterococci colonization in a neonatal intensive care unit: lessons from an outbreak.","authors":"F. Kılıç, Ş. Çalkavur, Ö. Olukman, Gulten Ercan, Y. Oruç, Dilek Ozkok, D. Okur, Gamze Gülfidan, I. Devrim, F. Atlihan","doi":"10.5222/BUCHD.2012.148","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.148","url":null,"abstract":"Objective: Vancomycin-resistant enterococci (VRE) have emerged as important causes of nosocomial infections in high-risk patients. Asymptomatic VRE colonized patients may act as potential reservoirs for other patients via hands. Infectious agents can spread rapidly within the same hospital. NICU are accepted to be at high-risk in terms of VRE colonization. We aimed to present our experience of a VRE colonization outbreak in the level-II NICU in 2010 and share the lessons we took from management of an outbreak. Methods: Rectal swab samples were collected from 506 infants following isolation of VRE from the index case and VRE colonization ratio was calculated. Active surveillance studies were sustained to determine the colonization ratios after the implementation of infection control measures. Results: A total of 3163 rectal swab samples were collected from 1155 infants. The VRE colonization ratio was calculated as 0.6% (n=7). Conclusion: It’s important to be aware of VRE colonization in hospitalized patients both for preventing sepsis, and for taking necessary infection control measures. Results of active surveillance studies in NICUs indicate a VRE colonization ratio of 0.5-2.2%. With the help of strict isolation measures and surveillance studies that we had implemented immediately after VRE isolation, we managed to get the outbreak under control in a short period of time. Glycopeptides have become irrevocable agents for late-onset sepsis of the newborn. VRE positivity was found to be 8.1% during the outbreak. Despite the modification of antibiotherapy protocols, we could reduce this ratio to 0.6% with the help of other precautions. We wanted to emphasize the restriction of unnecessary glycopeptide usage and the importance of strict adherence to infection control measures, especially handwashing and isolation.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131098573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Bayram, Y. Topçu, Gulcin Akinci, H. Çakmakçı, S. Kurul
{"title":"Cerebral hematoma associated with EBV infection: case report.","authors":"E. Bayram, Y. Topçu, Gulcin Akinci, H. Çakmakçı, S. Kurul","doi":"10.5222/BUCHD.2012.187","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.187","url":null,"abstract":"Structural vascular lesions are the biggest risk factor for spontaneous intracranial hemorrhage in children and many concomitant factors can trigger parenchymal hemorrhage. If neonatal intraventricular hemorrhage and traumatic lesions are excluded, cerebral hemorrhage is more common than ischemic infarct in childhood. Atherosclerotic disease, ischemic heart disease and hemorrhages caused by hypertension are frequently seen in adults but infectious and inflammatory causes of stroke is more common in children. Although primary Epstein Barr virus (EBV) infection usually causes infectious mononucleosis in patients who developed neurologic complications of EBV infection, usually clinical findings of infectious mononucleosis can not be detected. In this report, we presented a 13-year-old girl with acute hemorrhagic stroke accompanied by central venous angioma and concomitant asymptomatic acute EBV infection. Though rarely seen infectious etiology of stroke should be considered in childhood stroke cases.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127429551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Gozmen, H. Apa, Ilker Gunay, E. Ozbek, F. Genel, S. Bayram, I. Devrim
{"title":"Our experience in neonatal varicella.","authors":"S. Gozmen, H. Apa, Ilker Gunay, E. Ozbek, F. Genel, S. Bayram, I. Devrim","doi":"10.5222/BUCHD.2012.154","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.154","url":null,"abstract":"Objective: Varicella infection is common in childhood but it is less common in the neonatal period. Varicella infection in pregnancy and neonatal period is clasified as congenital, perinatal and neonatal varicella. Characteristics of patients, routes of transmission and course of the disease were evaluated retrospectively in newborns with neonatal varicella in this study. Methods: Charts of neonates admitted to Dr. Behçet Uz Children’s Hospital between October 2011 and May 2012 with varicella eruption after postnatal ten days were retrospectively reviewed. Results: Thirteen neonates were enrolled in this study. Mean age was 23±5.7 days. Eight patients were female and five patients were male. Mean gestational age was 38.2±1.1 weeks. Seven patients had a history of contact with a person with active varicella infection. Five of them were siblings. Six patients had no contact. Two mothers had varicella eruption after the third day of delivery. All patients had received intravenous acyclovir injections three times a day with a dose of 10 mg/kg for three to five days and after discharge they had taken oral acyclovir with the same dose until the seventh day. One patient with infiltration in chest x-ray and one with infected lesions of varicella had ampicillin-sulbactam in addition to acyclovir. Conclusion: It is important to start acyclovir treatment within twenty four-hours with the first sign of eruption in the patients with a diagnosis of neonatal varicella. Acyclovir in the treatment of neonatal varicella decreases the morbidity and mortality and has a good safety profile. But, larger scale controlled studies are needed.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"03 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131012048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of iron deficiency in children with attention deficit/hpyperactivity disorder.","authors":"H. Oğrag, Ö. Bağ, A. Kutlu, A. Öztürk","doi":"10.5222/BUCHD.2012.127","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.127","url":null,"abstract":"Objective: Attention Deficit-Hyperactivity Disorder is a common neurobiological syndrome of the childhood. Iron deficiency is suggested to be an etiologic factor of Attention Deficit-Hyperactivity Disorder because of its role in the dopamine metabolism. The objective of this study is to evaluate iron deficiency in patients with Attention Deficit-Hyperactivity Disorder in comparison with healty children and to predict the severity of the symptoms on admission with reference to serum ferritin levels. Methods: Fifty children with Attention DeficitHyperactivity Disorder and fifty age and sex-matched control subjects were evaluated. Ferritin levels in both groups and their relationship with DSM-4 score were investigated. Results: The mean serum ferritin level in the patient group was 27±13.2 ng/ml which was significantly lower than the control group with a mean value of 41±26 ng/ml. In Attention Deficit-Hyperactivity Disorder group, serum ferritin levels did not correlate with the score of the disease described in DSM-4 (r=0.09; p>0.05). Conclusion: In conclusion, iron deficiency is an etiologic factor in Attention DeficitHyperactivity Disorder but the severity of the symptoms on admission did not correlate with serum ferritin levels.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121671852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Bulut, Şevket Balli, F. Atlihan, T. Meşe, Ş. Çalkavur, Ö. Olukman
{"title":"Retrospective evaluation of patients with congenital heart disease monitored in the neonatology department.","authors":"G. Bulut, Şevket Balli, F. Atlihan, T. Meşe, Ş. Çalkavur, Ö. Olukman","doi":"10.5222/BUCHD.2012.141","DOIUrl":"https://doi.org/10.5222/BUCHD.2012.141","url":null,"abstract":"Amaç: Hastanemiz yenidoğan yoğun bakım ünitesinde doğumsal kalp hastalığı tanısı alan yenidoğanların sıklık, risk faktörleri ve tanısal ipuçları açısından geriye dönük değerlendirilmesi. Yöntemler: Eylül 2007-Eylül 2009 tarihleri arasında yenidoğan yoğun bakım servisinde yatırılarak tedavi gören 6297 yeni doğandan 367’si ekokardiyografi yapılarak değerlendirildi. Sürekli değişkenler ile ilgili farklılıkların varlığı student t-testi ile kategorik değişkenler arasında farklılık olup olmadığı ise ki-kare testi ile araştırıldı. Bulgular: Ortalama anne yaşı 27±8 (17-42) olarak bulundu. Yüz beş hastada doğumsal kalp hastalığı bulunduğu görüldü. Hastaların %21.9’u matür, %78.1’i prematürdü. Doğumsal kalp hastalığı sıklığı sıklığı %1.6 olarak belirlendi. Ailelerin %16’sında akraba evliliği bulunuyordu. Tanı alan hastaların %61.9’unu siyanotik grup oluşturuyordu. Doğumsal kalp hastalığı tanısı alan bebeklerin %83.9’u solunum sıkıntısı nedeniyle yatmaktaydı. Doğumsal kalp hastalığı tanısı alan yenidoğanlardan en sık kardiyoloji konsültasyonu istenme nedeni %39.3 ile üfürümdü. Doğumsal kalp hastalığı tanısı alan hastalar içinde en sık saptanan kardiak defektler ventriküler septal defekt (%34.3), siyanotik doğumsal kalp hastalıkları içerisinde ise en sık büyük arterlerin komplet transpozisyonu tespit edildi. Otuz dört hasta kalp cerrahisi geçirdi. On bir hasta cerrahi öncesi, 2’si de cerrahi sonrası komplikasyonlar nedeniyle kaybedildi. En sık ölüm nedeni kalp yetmezliği ve sepsis iken en sık eşlik eden kardiyak defektin hipoplastik sol kalp olduğu tespit edildi. Sonuç: Yenidoğanların kardiyak hemodinamiği farklı olduğu için yatırılan her hastaya belirgin kardiyak semptom olmasa bile dikkatli kardiyak muayene ve ekokardiyografik değerlendirme yapılması önemlidir.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"618 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131508545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The evaluation of pediatric patients with tularemia.","authors":"O. Ceylan, M. Kose, M. Öztürk","doi":"10.5222/buchd.2012.131","DOIUrl":"https://doi.org/10.5222/buchd.2012.131","url":null,"abstract":"Objective: Tularemia is a zoonotic infectious disease which is caused by Francisella tularensis. In recent years, the changes in the population and distribution of reservoirs and vectors in parallel to the climatic changes and inclusion of tularemia in the list of diseases whose notification are compulsory since 2005 caused an increasing number of cases reported from different regions. As a result, it is understood that F. Tularensis is endemic in Turkey. In that study,13 children with tularemia are presented. The aim of the study is to determine the effects of elapsed time between the onset of symptoms and the admission to the hospital on prognosis. Methods: Thirteen patients diagnosed with tularemia in Children Infection Polyclinic between the years of 2009 and 2011 were taken to the study. They were diagnosed by microagglutination test. The titers of 1/160 and more were accepted as positive. Results: Six patients were female. The median age was 10 years (6-14 yrs). The most common complaints of patients were swellings of the neck and armpits, sore throat and fever. Streptomycin (30 mg/kg/day) was used for 11 patients and gentamicin (5 mg/kg/day) for 1 patient. The median treatment period was 14 days (7-20) for 5 patients who were admitted to the hospital within 7 days and no complications occurred. The median treatment period was calculated as 39 days (24-60) for 8 patients who are admitted to the hospital after 14 days. Conclusions: The treatment period was short for the patients admitted to the hospital within 7 days after the beginning of complaints and any complications did not occur Therefore, when faced with patients who are required distinctive diagnosis of tonsillopharyngitis or lymphadenopathy, the history of living in endemic regions or not and travelling to those regions should be taken into consideration, and in suspect case of tularemia, the treatment should be applied immediately.","PeriodicalId":428200,"journal":{"name":"Journal of Dr. Behcet Uz Children's Hospital","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123877466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}