Cerebral hematoma associated with EBV infection: case report.

Abstract

Structural vascular lesions are the biggest risk factor for spontaneous intracranial hemorrhage in children and many concomitant factors can trigger parenchymal hemorrhage. If neonatal intraventricular hemorrhage and traumatic lesions are excluded, cerebral hemorrhage is more common than ischemic infarct in childhood. Atherosclerotic disease, ischemic heart disease and hemorrhages caused by hypertension are frequently seen in adults but infectious and inflammatory causes of stroke is more common in children. Although primary Epstein Barr virus (EBV) infection usually causes infectious mononucleosis in patients who developed neurologic complications of EBV infection, usually clinical findings of infectious mononucleosis can not be detected. In this report, we presented a 13-year-old girl with acute hemorrhagic stroke accompanied by central venous angioma and concomitant asymptomatic acute EBV infection. Though rarely seen infectious etiology of stroke should be considered in childhood stroke cases.