Pneumon最新文献

{"title":"Lung infiltrates and fever: Is it pneumonia or not?","authors":"K. Lyroni, E. Vasarmidi, N. Tzanakis, K. Antoniou","doi":"10.18332/pne/157587","DOIUrl":"https://doi.org/10.18332/pne/157587","url":null,"abstract":"1 A 62-year-old man presented in the emergency department with fever and dry cough. He was a current smoker (20 pack-years), obese (ΒΜΙ: 43 kg/m2), and he started treatment for benign prostate hyperplasia following an episode of macroscopic hematuria about two months ago (unavailable laboratory tests at that time). No other past medical history was reported. Physical examination on admission revealed crackles in lung lower parts. PCR test for SARS-CoV-2 was negative. Blood tests showed increased C-reactive protein, anemia, and hypoalbuminemia, while arterial blood gas analysis displayed hypoxemia (pO2: 69 mmHg, pCO2: 36 mmHg, pH: 7.47, HCO3: 26 mmol/L). The chest X-ray showed infiltrates in both lungs (Figure 1). He was admitted at the Respiratory Department, and he was treated with antibiotics with a provisional diagnosis of community acquired pneumonia. In less than 24 hours after admission, he experienced hemoptysis. A thorough work-up was initiated measuring urine dipstick, which showed proteinuria and hematuria, and blood autoantibodies titers were ordered. Chest CT scan findings included ground glass opacities (GGOs) and crazy paving; and patchy GGOs associated with smooth septal thickening. Additionally, ‘air bronchogram’; visualization of bronchial structures containing air in the context of consolidation areas, and ‘dark bronchus sign’; and darker bronchus in the context of GGOs, are shown (Figure 2). These findings indicate hemorrhagic alveolitis or edema, thus the provisional diagnosis was alveolar hemorrhage. Vasculitis was put forward as the most probable diagnosis, as those abnormalities, along with the bilateral, para-hilar distribution (Figure 2), are common in diffuse alveolar hemorrhage associated with vasculitis. Therefore, the patient was to be subjected to plasma exchange. At that time he was rapidly deteriorating, experiencing massive hemoptysis and severe respiratory failure, and was transferred to the intensive care unit. The patient was intubated but did not manage to be stabilized and died a few hours later. The next day, serology revealed high titer of MPO/p-ANCA antibodies and the final diagnosis was ANCA-associated vasculitis with lung and renal involvement. Herein, we described a patient who presented with symptoms typical for pneumonia, who deteriorated a few hours after admission. The rapid progression and the presence of hemoptysis led to a rethink of the provisional diagnosis. ANCA-associated vasculitis (AAV) represents systemic, small-vessel vasculitis and is characterized by the loss of tolerance to neutrophil antigens and the development of autoantibodies to the neutrophil proteins MPO and PR3. They are considered to be rare with a prevalence of 46–184 per million people1. Lung involvement is well described in ANCA-associated small vessel vasculitis2, and a recent study found that the majority of patients with ANCA-associated small vessel vasculitis, who were admitted with acute respiratory failure, experience","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83782701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgery for pulmonary giant bullae","authors":"R. Costa, Anita Paiva, J. Maciel, P. Fernandes, A. Magalhães","doi":"10.18332/pne/159280","DOIUrl":"https://doi.org/10.18332/pne/159280","url":null,"abstract":"Elective bullectomy is rarely performed in chronic obstructive pulmonary disease patients. Selecting patients who will benefit the most from surgery is a challenging process. We report a case of a patient who underwent elective bullectomy to reduce symptoms and the severity of the exacerbations. One year after surgery he maintains improvement in quality of life despite the underlying emphysema. It is hard to identify only one test to predict which patients will benefit from the surgical treatment, but relief of symptoms in chronic obstructive pulmonary disease patients should be a priority over pulmonary function.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78232840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy in cystic fibrosis in the era of CFTR modulators: A case series","authors":"M. Sionidou","doi":"10.18332/pne/157586","DOIUrl":"https://doi.org/10.18332/pne/157586","url":null,"abstract":"Table 2, her respiratory","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74628310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive hemoptysis in a patient with pulmonary tuberculosis complicated by cavitation with an air crescent sign","authors":"M. Tavares, Filipa Fernandes, É. Almeida","doi":"10.18332/pne/157585","DOIUrl":"https://doi.org/10.18332/pne/157585","url":null,"abstract":"the air crescent sign is a characteristic imaging finding of aspergilloma, it can be found in other entities including tuberculosis 2 , neoplasms (particularly bronchial carcinoma), Rasmussen’s aneurysm, and intracavitary clots. Other, rarer causes include foreign bodies, thick pus, dehydrated caseous material, teratoma, and hydatid disease 3,4 .","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89917776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of fractional exhaled nitric oxide use among doctors working in a local respiratory department","authors":"Etienne Ceci Bonello, Rebecca Bianco, C. Gouder","doi":"10.18332/pne/157588","DOIUrl":"https://doi.org/10.18332/pne/157588","url":null,"abstract":"cut-off of <12 months and ≥12 months working in our respiratory department was set to check whether there is a statistical significance in the knowledge of FeNO testing amongst these two categories. The participants working in the department for <12 months are junior trainees currently rotating in the ABSTRACT INTRODUCTION The aim of this survey is to assess the knowledge regarding fractional exhaled nitric oxide (FeNO) testing among our junior and senior physicians currently working within the respiratory department. METHODS All medical doctors above foundation level working in the respiratory department for at least 3 months at Mater Dei Hospital were asked to complete a questionnaire with a total of 19 true or false questions. Questions were based on current international guidelines and recommendations. RESULTS Our cohort included a total of 25 doctors. The mean age of experience working as a physician was 8 years; 84% of doctors (n=21) were aware that FeNO testing is available at our hospital. Questions assessing clinical indications and interpretation of FeNO in asthma and different respiratory conditions showed overall significantly better results between junior and senior trainees (p=0.013), though still lacking in certain aspects especially in conditions unrelated to asthma. CONCLUSIONS Our results show that doctors working in our department are overall knowledgeable about the use of FeNO in relation to the diagnosis and management of asthma. However, its use and interpretation in relation to other respiratory conditions and co-morbidities is lacking. This emphasizes the need to educate local respiratory trainees further on FeNO testing.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85359138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ten years of the website for patients with asthma (www.myasthma.gr) by the Asthma Working Group of\u0000the Hellenic Thoracic Society","authors":"E. Fouka, K. Samitas, P. Bakakos","doi":"10.18332/pne/157584","DOIUrl":"https://doi.org/10.18332/pne/157584","url":null,"abstract":"","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83714083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment for tuberculosis due to sensitive strains: To shorten or not to shorten?","authors":"K. Manika, A. Loukeri, M. Sionidou, C. Moschos, A. Papavasileiou","doi":"10.18332/pne/156697","DOIUrl":"https://doi.org/10.18332/pne/156697","url":null,"abstract":"","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88328209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of tracheobronchial amyloidosis presenting\u0000with acute myeloid leukemia","authors":"S. Demir, A. Kansu, A. Gemici, İrem Özöver Çelik","doi":"10.18332/pne/155919","DOIUrl":"https://doi.org/10.18332/pne/155919","url":null,"abstract":"Flexible","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73357187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes mellitus and hypertension as risk factors of acute kidney injury induced by COVID-19: A systematic review and meta-analysis","authors":"Ilham Setiawan, Sirin Salsabila, Buyung Prasetyawan, M. Ilmawan, Atma Gunawan, B. Daryanto, J. Fajar","doi":"10.18332/pne/154602","DOIUrl":"https://doi.org/10.18332/pne/154602","url":null,"abstract":"INTRODUCTION Acute kidney injury (AKI) is one of the severe complications of COVID-19. The two distinct medical conditions sharing similar comorbidities are diabetes and hypertension. However, the correlation between AKI and COVID-19 patients with diabetes and/or hypertension, has not been extensively discussed. This study aims to assess the risk factors of AKI induced by COVID-19, using a meta-analysis approach. METHODS A meta-analysis was carried out by reviewing the latest relevant studies on online databases such as PubMed, Google Scholar and Medline, up to 21 March 2022. The required information related to hypertension and diabetes as the potential risk factors of AKI induced by COVID-19, was extracted. The association was analyzed using pooled odds ratio (OR) and a 95% confidence interval (95% CI). RESULTS We analyzed 29 studies consisting of 10698 AKI patients with COVID-19 and 20917 controls. Our results show that patients with diabetes test)=0.0001, pE (Egger test)=0.8074) and hypertension (OR=1.7921;95% develop AKI when infected with COVID-19. CONCLUSIONS Diabetes and hypertension are prominent risk factors of acute kidney injury induced by COVID-19.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73911652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survival analysis of cutaneous metastases in lung cancer: A 25-year experience","authors":"R. Natal, M. Oliveira, Adelino Amaral, Fátima Cabral, R. Gomes, Luís Ferreira","doi":"10.18332/pne/155918","DOIUrl":"https://doi.org/10.18332/pne/155918","url":null,"abstract":"lesion confirmed histologically to be a cutaneous metastasis. Patients with suspicious cutaneous lesions without a skin biopsy, were excluded. Methods A retrospective study was conducted with patients diagnosed with lung cancer and cutaneous metastases, from January ABSTRACT INTRODUCTION Cutaneous metastases from lung cancer are rare and their presence has been considered a sign of an already disseminated and poor-prognosis disease. The main objective of this study is to evaluate the survival of the patients with cutaneous metastases from lung cancer. METHODS A retrospective study was conducted with patients diagnosed with cutaneous metastases from lung cancer, confirmed by skin biopsy, from January 1995 to December 2020, in our local health unit. Descriptive and survival analysis were performed, considering a level of significance of 5%. RESULTS From a total of 1172 cases of lung cancer, eleven patients (0.94%) had a skin tissue confirmation of cutaneous metastasis, predominantly male (63.6%) with median age of 78 years, and past or active smoking history in 63.6%. In 6 patients (54.5%), this finding was diagnosed simultaneously with primary lung cancer, and adenocarcinoma was the main histological type (63.6%). The most frequent presentation was a single nodule in the anterior chest wall, and all skin lesions had histological concordance with lung cancer. The median overall survival was 2 months (range: 0–27) and from the diagnosis of cutaneous metastasis was 1 month (range: 0–18). Survival analysis revealed that the simultaneous diagnosis of cutaneous metastases and lung cancer shortens survival (2.50 vs 13.20 months; p=0.032).","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74377073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}