IF 0.7

Pneumon Pub Date : 2022-12-07 DOI: 10.18332/pne/157014

P. Bakakos, E. Fouka, P. Galanakis, K. Katsoulis, K. Kostikas, S. Loukides, N. Mathioudakis, Konstantinos Porpodis, K. Samitas, P. Steiropoulos, E. Zervas

{"title":"Protocol, rationale and design of the PHOLLOW\u0000cross-sectional and retrospective chart review\u0000study to assess the prevalence and characterize the\u0000patient profile, clinical features and disease burden\u0000of type-2 low severe asthma in routine care settings\u0000in Greece","authors":"P. Bakakos, E. Fouka, P. Galanakis, K. Katsoulis, K. Kostikas, S. Loukides, N. Mathioudakis, Konstantinos Porpodis, K. Samitas, P. Steiropoulos, E. Zervas","doi":"10.18332/pne/157014","DOIUrl":"https://doi.org/10.18332/pne/157014","url":null,"abstract":"Type 2 (T2)-low severe asthma (SA) presents a distinct subpopulation for which, in lack of a consistent classification system, epidemiological and clinical outcome data remain unclear and therapeutic needs remain largely unmet. The aim of the PHOLLOW real-world study is to assess the prevalence and predictors of T2-low SA, and depict the patient profile, clinical features, treatment patterns and disease burden using clinical and patient-reported outcomes (PROs) in routine settings in Greece. This is a cross-sectional and retrospective chart review 2-part study that will enroll 600 adult outpatients with SA over a 1-year period by 20–30 asthma specialists. A new SA phenotype classification system and two different definitions proposed herein will be used to categorize patients into definite or possible T2-low (unlikely or least likely T2-high) SA, and definite/most likely or possible/likely T2-high SA, based on a composite measure of airway inflammation markers (blood eosinophil counts, fractional exhaled nitric oxide), allergic/atopic status and age-of-onset phenotype, taking into consideration the current receipt of biologic and/or maintenance oral corticosteroid treatment and response to it. Part A will collect top-level data for all participants to assess T2-low SA prevalence and predictors. T2-low SA patients will proceed to part B, where further data and PROs assessing asthma symptom control, quality of life, anxiety, depression, work productivity and activity impairment will be collected.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90484706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inhalers and the Environment: Pollution, Plastics and Policy 吸入器和环境:污染、塑料和政策

IF 0.7

Pneumon Pub Date : 2022-11-29 DOI: 10.18332/pne/154608

Monbi Chakma, O. Usmani

引用次数: 0

Outcomes of hospitalized COVID-19 patients belonging to ethnic/racial minorities in Greece 希腊少数民族/种族住院COVID-19患者的结局

IF 0.7

Pneumon Pub Date : 2022-11-04 DOI: 10.18332/pne/154601

Michaella Alexandrou, S. Daskalopoulou, Anna-Louiza Haliassou, E. Kranidioti, E. Margellou, A. Panagopoulos, E. Papageorgiou, Artemis Rodopoulou, G. Stavropoulou, Apostolos G. Pappas, I. Kalomenidis

{"title":"Outcomes of hospitalized COVID-19 patients belonging to ethnic/racial minorities in Greece","authors":"Michaella Alexandrou, S. Daskalopoulou, Anna-Louiza Haliassou, E. Kranidioti, E. Margellou, A. Panagopoulos, E. Papageorgiou, Artemis Rodopoulou, G. Stavropoulou, Apostolos G. Pappas, I. Kalomenidis","doi":"10.18332/pne/154601","DOIUrl":"https://doi.org/10.18332/pne/154601","url":null,"abstract":"INTRODUCTION Research suggests that racial minorities are overrepresented in the number of COVID-19 related deaths compared to people of White origin. This is the first study to assess racial differences in the clinical characteristics and outcomes of COVID-19 positive patients, hospitalized in Greece. METHODS This retrospective, cross-sectional study included 628 COVID-19 hospitalized patients, from 10 September to 31 December 2020. We compared data concerning gender, age, comorbidities and outcome, between patients of European and non-European origin. Moreover, we applied logistic regression in which the outcome, in our case in-hospital death, was assessed with race, age, sex, and Charlson Comorbidity Index (CCI) score. RESULTS In the first and unadjusted race-only logistic regression model, non-Europeans (OR=0.057;95% CI: 0.008-0.411, p=0.005) were less likely than European patients to die in the hospital. However, controlling for sex, age and CCI score resulted in non-significant differences. CONCLUSIONS There are a lot of statistically significant differences between European and non-European COVID-19 hospitalized patients regarding their clinical characteristics, with the second presenting a lower hospital mortality rate, but after adjusting for age, sex and CCI score, race seems to be not significant. Copyright © 2022 Alexandrou M. et al.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82912110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Capturing patient-centered outcomes using innovative technologies in adults with severe eosinophilic asthma on benralizumab: Τhe EMPOWAIR real-world study design 使用创新技术在使用benralizumab治疗的成人严重嗜酸性粒细胞哮喘患者中获取以患者为中心的结果:Τhe EMPOWAIR真实世界研究设计

IF 0.7

Pneumon Pub Date : 2022-10-07 DOI: 10.18332/pne/154605

K. Kostikas, P. Bakakos, Petros A. Galanakis, G. Hillas, G. Konstantinou, M. Makris, N. Mathioudakis, Konstantinos Porpodis, N. Rovina, E. Zervas, S. Loukides

{"title":"Capturing patient-centered outcomes using innovative technologies in adults with severe eosinophilic asthma on benralizumab: Τhe EMPOWAIR real-world study design","authors":"K. Kostikas, P. Bakakos, Petros A. Galanakis, G. Hillas, G. Konstantinou, M. Makris, N. Mathioudakis, Konstantinos Porpodis, N. Rovina, E. Zervas, S. Loukides","doi":"10.18332/pne/154605","DOIUrl":"https://doi.org/10.18332/pne/154605","url":null,"abstract":"Severe eosinophilic asthma (SEA) is associated with poor disease control and compromised health-related quality of life (HRQoL), leading to a substantial psychosocial and economic disease burden. Benralizumab, an interleukin-5-alpha receptor monoclonal antibody, is approved as an add-on maintenance treatment for SEA, yet real-world evidence of its effectiveness is limited. EMPOWAIR is a non-interventional, multicenter, 48-week prospective cohort study aiming to evaluate the clinical effectiveness and the patient-perceived impact of benralizumab on HRQoL, sleep quality, depression, anxiety, work productivity and activity impairment among SEA patients treated in routine care settings in Greece. The study will also engage advanced remote patient monitoring technologies using portable spirometers and wearable activity trackers to collect data on lung function parameters and physical activity. The study plans to consecutively enroll 150 adult patients treated by lung specialists practicing in various healthcare settings across the country over an 18-month recruitment Eligible patients must be newly prescribed benralizumab per the approved label. Primary data will be collected at enrollment and 4, 16, 32, and 48 weeks after initiation through routine clinic or as the standard clinical assess the change from baseline in HRQoL, as measured by the St. George’s Respiratory Questionnaire (SGRQ), and to estimate the proportion of patients achieving a minimum clinically important improvement in respiratory health status, defined as ≥ 4-point reduction from baseline in SGRQ total score, after 16 weeks of benralizumab treatment. The study rationale, design and protocol, are described herein.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80479196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The role of private primary care pulmonologists network in Greece in the first year of COVID-19 pandemic 在2019冠状病毒病大流行的第一年，希腊私营初级保健肺病学家网络的作用

IF 0.7

Pneumon Pub Date : 2022-09-16 DOI: 10.18332/pne/153021

Stylianos Vittorakis *, Vasiliki Georgakopoulou *, G. Apollonatos, S. Loukides, A. Liapikou

{"title":"The role of private primary care pulmonologists network in Greece in the first year of COVID-19 pandemic","authors":"Stylianos Vittorakis *, Vasiliki Georgakopoulou *, G. Apollonatos, S. Loukides, A. Liapikou","doi":"10.18332/pne/153021","DOIUrl":"https://doi.org/10.18332/pne/153021","url":null,"abstract":"INTRODUCTION The COVID-19 pandemic has overwhelmed the capacities of healthcare systems. Primary care physicians had a pivotal role in reducing the unnecessary access of suspected and confirmed cases to hospitals, and they substantially contributed to the success of vaccination programs. In this study, we aim to determine the role of the Greek private primary care pulmonologists (PPCPs) network during the first year of the pandemic. METHODS An electronic questionnaire consisting of 28 simple questions was administered to PPCPs by e-mail or by sharing a link in private social networking groups. RESULTS A total of 150 PPCPs completed the study. According to their answers, they examined a significant portion of suspected and confirmed COVID-19 cases, and they offered to several patients blood testing and chest radiography. PPCPS maintained close contact with both patients that had faceto-face assessment and patients managed remotely with a great number of telephone contacts. The majority of PPCPs provided information for COVID-19 vaccination by telephone for more than 20 patients weekly. CONCLUSIONS PPCPs offered high quality and specialized support for COVID-19 patients. Besides, they supported the national vaccination program by informing a substantial number of patients.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90886013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A life-threatening massive hemoptysis case in the course of dual antiplatelet therapy with ticagrelor 替格瑞洛双重抗血小板治疗过程中危及生命的大咯血病例

IF 0.7

Pneumon Pub Date : 2022-09-15 DOI: 10.18332/pne/152774

Dimitrios Molyvas, M. Kipourou, S. Lampridis, K. Kipourou, P. Koutoukoglou, I. Tsanaktsidis, G. Spyropoulos, K. Katsoulis

{"title":"A life-threatening massive hemoptysis case in the course of dual antiplatelet therapy with ticagrelor","authors":"Dimitrios Molyvas, M. Kipourou, S. Lampridis, K. Kipourou, P. Koutoukoglou, I. Tsanaktsidis, G. Spyropoulos, K. Katsoulis","doi":"10.18332/pne/152774","DOIUrl":"https://doi.org/10.18332/pne/152774","url":null,"abstract":"A chest computed tomography (chest CT) revealed diffuse ground glass infiltrates in the apical and posterior segments of the right upper lobe and alveolar infiltrates in the remainder of the lungs, findings compatible with diffuse alveolar hemorrhage (images could not be retrieved due to technical reasons). Recent bleeding originating from the right bronchial tree was the finding of ABSTRACT Massive hemoptysis is a life-threatening medical condition which usually occurs in the course of parenchymal destructive diseases. We herein report the case of a 61-year-old male patient who presented with massive hemoptysis six months after commencement of dual antiplatelet therapy with acetylsalicylic acid and ticagrelor, for drug-eluting coronary stents. Control of bleeding with discontinuation of both antiplatelet agents, as well as negative imaging and laboratory studies for other pulmonary hemorrhage causes, indicate that either of the antiplatelet drugs or combination thereof was the cause of the pulmonary hemorrhage. In contrast to the previous limited case reports with pulmonary hemorrhage early during antiplatelet therapy with ticagrelor, this case highlights that it can even occur later in the course of antiplatelet therapy.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89253853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Investigating the factors affecting hookah smoking during the COVID-19 pandemic: Application of Protection Motivation Theory 新冠肺炎大流行期间水烟吸烟影响因素研究:保护动机理论的应用

IF 0.7

Pneumon Pub Date : 2022-08-04 DOI: 10.18332/pne/147970

S. Bashirian, Hossein Effatpanah, M. Barati, Salman Khazaee, A. Farhadinasab, Mojdeh Shokri, A. Poormohammadi, E. Ezati

{"title":"Investigating the factors affecting hookah smoking during the COVID-19 pandemic: Application of Protection Motivation Theory","authors":"S. Bashirian, Hossein Effatpanah, M. Barati, Salman Khazaee, A. Farhadinasab, Mojdeh Shokri, A. Poormohammadi, E. Ezati","doi":"10.18332/pne/147970","DOIUrl":"https://doi.org/10.18332/pne/147970","url":null,"abstract":"INTRODUCTION In recent decades, hookah use has been considered a common method of smoking. Since hookah use is one of the factors exacerbating the coronavirus disease, COVID-19, the present study aimed to determine the factors affecting hookah smoking during the COVID-19 pandemic using protection motivation theory (PMT). METHODS This is a cross-sectional study and conducted on 560 people aged ≥13 years living in Hamedan. Data were collected electronically using a researcher-made questionnaire consisting of three parts. The first, second, and third parts included demographic information, questions about hookah use, and information about the constructs of PMT, respectively. Data were analyzed using SPSS 22 software. RESULTS The mean age of the participants was 28.8 ± 9.6 years. In the regression analysis of perceived reward structures (β=0.378), perception sensitivity (β=0.208), self-efficacy (β=0.0166) were respectively the important predictors for the intention of hookah use behavior. Overall, the constructs of the PMT explain 71% of the variance of the changes in the behavioral intention construct in the participants. No significant relationship was observed between self-efficacy constructs (r=0.039) and perceived cost. The prevalence of hookah use before the COVID-19 pandemic in participants was 41.8%, which decreased to 35% during the COVID-19 pandemic. CONCLUSIONS A greater correlation between the constructs of the PMT concerning protective behaviors against COVID-19 emphasizes designing educational programs based on this theory and the role of media to increase people’s knowledge in preventive behaviors.","PeriodicalId":42353,"journal":{"name":"Pneumon","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78401998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Atypical presentation and progression of scleroderma associated interstitial lung disease 硬皮病相关间质性肺疾病的不典型表现和进展

IF 0.7

Pneumon Pub Date : 2022-08-04 DOI: 10.18332/pne/149901

Mackenzie Skov, S. Anees

引用次数: 1

Surgical approaches in obstructive sleep apnea syndrome: A review of techniques 阻塞性睡眠呼吸暂停综合征的手术入路:技术综述

IF 0.7

Pneumon Pub Date : 2022-07-25 DOI: 10.18332/pne/147971

Agathi Spyropoulou, Vassilis Spiropoulos, Georgia Spiropoulou, Christos Tsilivigos, K. Spiropoulos, N. Mastronikolis

引用次数: 1

Urinothorax: A pleural effusion that might not alwaysbe like urine 尿胸:不像尿液的胸腔积液